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Ishise Hisako  石瀬 久子

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ISHISE Hisako  石瀬 久子

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Researcher Number 30567194
Other IDs
Affiliation (Current) 2025: 兵庫医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2020 – 2024: 兵庫医科大学, 医学部, 講師
2018 – 2019: 兵庫医科大学, 医学部, 助教
2017: 兵庫医科大学, 医学部, その他(移行)
2016: 兵庫医科大学, 医学部, 研究生(研究員)
2015: 兵庫医科大学, 医学部, 病院助手
2012 – 2013: 兵庫医科大学, 医学部, 病院助手
Review Section/Research Field
Principal Investigator
Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery
Except Principal Investigator
Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery
Keywords
Principal Investigator
創傷治癒 / 慢性炎症 / セノリティクス / 炎症 / 細胞老化 / 老化細胞 / ケロイド / NFκB / IL-6 / TRPC … More / Ca channel / 皮膚線維芽細胞 / 機械的伸展刺激 / 肥厚性瘢痕 … More
Except Principal Investigator
創傷治癒 / TRPC3 / 機械的刺激 / 酸化ストレス / エクソソーム / DICOM / CT / ディープラーニング / 自動診断 / 顔面骨骨折 / 難治性潰瘍 / 持続閉鎖陰圧療法 / 微弱電流刺激療法 / Endothelin Receptor B / NFAT / end-to-side neurorrhaphy / facial nerve / 端側神経縫合 / ハイブリッド型人工神経 / 顔面神経再建 / 顔面神経 / 末梢神経 / 人工神経 / 神経再建 / 顔面神経麻痺 / 免疫 / 炎症 / EDNRB / 肥厚性瘢痕 / 機械的伸展刺激 / Calreticulin / Adiponectin / 糖尿病 / 血清由来Nanoparticle / 血清由来nanoparticle / イオンチャネル / カルシウム動態 / カルシウムイオンチャネル / TRPCチャネル Less
  • Research Projects

    (10 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (8 People)
  •  微弱電流刺激療法と閉鎖陰圧療法の併用による難治性潰瘍の新たな治療法の開発

    • Principal Investigator
      藤原 敏宏
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Hyogo Medical University
  •  Development of a computer assisting diagnostic system for facial bone fracture.

    • Principal Investigator
      西本 聡
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Hyogo Medical University
  •  Basic research on exosomes in the wound healing process

    • Principal Investigator
      河合 建一郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Hyogo Medical University
  •  Senescent cells can impact on chronic inflammation of keloids.Principal Investigator

    • Principal Investigator
      石瀬 久子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Hyogo Medical University
  •  Elucidation of the Mechanism for Acquiring Oxidative Stress Resistance during the Skin Wound Healing Process.

    • Principal Investigator
      Kawai Kenichiro
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Hyogo Medical University
  •  The relationship between the mechanical force and the interaction of skin-immune system during wound healing process

    • Principal Investigator
      Kawai Kenichiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Plastic surgery
    • Research Institution
      Hyogo Medical University
  •  Analysis of nerve regeneration in a hybrid artificial nerve containing basic-FGF

    • Principal Investigator
      Kakibuchi Masao
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Hyogo Medical University
  •  The role of the serum-derived Nanopaticle in the diabetic wound healing disorders

    • Principal Investigator
      Kawai Kenichiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Hyogo Medical University
  •  機械的伸展刺激が肥厚性瘢痕・ケロイドを発生させるメカニズムの解明Principal Investigator

    • Principal Investigator
      石瀬 久子
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Hyogo Medical University
  •  Effects of oxidative stress on wound healing and hypertrophic scar formation process

    • Principal Investigator
      FUJITA Kazutoshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Hyogo Medical University

All 2023 2015 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Stretching Promotes Wound Contraction Through Enhanced Expression of Endothelin Receptor B and TRPC3 in Fibroblasts2023

    • Author(s)
      Kenichiro Kawai, Hisako Ishise, Tateki Kubo, Barrett Larson, Toshihiro Fujiwara, Soh Nishimoto, Masao Kakibuchi
    • Journal Title

      Plastic and Reconstructive Surgery Global Open

      Volume: 11 Issue: 4 Pages: e4954-e4954

    • DOI

      10.1097/gox.0000000000004954

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09856
  • [Journal Article] Hypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation2015

    • Author(s)
      Hisako Ishise, Barrett Larson, Yutaka Hirata, Toshihiro Fujiwara, Soh Nishimoto, Tateki Kubo, Ken Matsuda, Shigeyuki Kanazawa, Yohei Sotsuka, Kazutoshi Fujita, Masao Kakibuchi & Kenichiro Kawai
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 11620-11620

    • DOI

      10.1038/srep11620

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] 皮膚創部における酸化ストレスとTRPCチャネルの関係2015

    • Author(s)
      河合建一郎, 石瀬久子, 西本聡, 藤原敏宏, 曽束洋平, 藤田和敏, 外岡真紀, 齋藤拓也, 垣淵正男
    • Organizer
      第7回日本創傷外科学会総会
    • Place of Presentation
      東京ドームホテル ( 東京・文京区)
    • Year and Date
      2015-07-24
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] Calcium Entry Via TRPC3 Channels Transduce Mechanical Force And Accerelate Wound Contraction2015

    • Author(s)
      Kenichiro Kawai, Hisako Ishise, Barrett Larson, Soh Nishimoto, Toshihiro Fujiwara, Masao Kakibuchi
    • Organizer
      Plastic Surgery Research Council 60th Annual Meeting
    • Place of Presentation
      Seattle (USA)
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] TRPC3 Channels Regulate Expression of Fibronectin Via NFκB Signling In Response to Cyclic Strain And Contribute to Hypertrophic Scar Formation2015

    • Author(s)
      Kenichiro Kawai, Hisako Ishise, Barrett Larson, Soh Nishimoto, Toshihiro Fujiwara, Masao Kakibuchi
    • Organizer
      Plastic Surgery Research Council 60th Annual Meeting
    • Place of Presentation
      Seattle (USA)
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] TRPCチャネルと創傷治癒2015

    • Author(s)
      河合建一郎, 石瀬久子, 西本聡, 藤原敏宏, 曽束洋平, 藤田和敏, 外岡真紀, 垣淵正男
    • Organizer
      第24回日本形成外科学会基礎学術集会
    • Place of Presentation
      岩手県民会館 ( 岩手・盛岡市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] Serum derived nanoparticles increase the rate of cataneous wound closure2013

    • Author(s)
      Kenichiro Kawai, Barrett Larson, Hisako Ishise, Antoine L. Carré, Soh Nishimoto, Michael T. Longaker, H Peter Lorenz, Masao Kakibuchi.
    • Organizer
      The 22nd China-Japan Joint Congress on Plastic Surgery
    • Place of Presentation
      Dalian, China
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] THE MECHANICAL STRECHING FORCE INCREASES IL-6 PRODUCTION IN TRPC3 OVEREXPRESSING FIBROBLASTS2012

    • Author(s)
      HISAKO ISHISE
    • Organizer
      4TH Congress of the World Union of Wound Healing Societies
    • Place of Presentation
      YOKOHAMA
    • Data Source
      KAKENHI-PROJECT-24791928
  • [Presentation] 機械的伸展刺激による肥厚性瘢痕を引き起こすメカニズムについて~TRPC3 channelの役割~2012

    • Author(s)
      石瀬久子
    • Organizer
      第42回日本創傷治癒学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24791928
  • [Presentation] 細胞力覚チャネルTRPC3が創収縮に果たす役割について

    • Author(s)
      河合建一郎、石瀬久子、藤田和敏、曽束洋平、藤原敏宏、西本聡、垣淵正男
    • Organizer
      第23回日本形成外科学会基礎学術集会
    • Place of Presentation
      長野県松本市
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] 創収縮におけるTRPC3の役割について

    • Author(s)
      河合建一郎、石瀬久子、西本聡、藤原敏宏、曽束洋平、藤田和敏、木下将人、齋藤拓也、大島遙、垣淵正男
    • Organizer
      第6回日本創傷外科学会総会・学術集会
    • Place of Presentation
      香川県高松市
    • Year and Date
      2014-07-24 – 2014-07-25
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] CALCIUM ENTRY VIA TRPC3 CHANNELS TRANSDUCE MECHANICAL FORCE AND ACCERELATE WOUND CONTRACTION

    • Author(s)
      Kenichiro Kawai, Hisako Ishise, Barrett Larson, Soh Nishimoto, Toshihiro Fujiwara, Masao Kakibuchi
    • Organizer
      The 60th Plastic Surgery Research Council
    • Place of Presentation
      Seattle, Washington USA
    • Year and Date
      2015-05-14 – 2015-05-16
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] 機械的刺激応答チャネルとしてのTRPC3の役割ーFibronectin発現制御機構についてー

    • Author(s)
      石瀬久子、河合建一郎、藤田和敏、曽束洋平、藤原敏宏、西本聡、垣淵正男
    • Organizer
      第23回日本形成外科学会基礎学術集会
    • Place of Presentation
      長野県松本市
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-25462808
  • [Presentation] TRPC3 CHANNELS REGULATE EXPRESSION OFFIBRONECTIN VIA NFκB SIGNLING IN RESPONSE TO CYCLIC STRAIN AND CONTRIBUTE TO HYPERTROPHIC SCAR FORMATION

    • Author(s)
      Hisako Ishise, Kenichiro Kawai, Barrett Larson, Soh Nishimoto, Toshihiro Fujiwara, Masao Kakibuchi
    • Organizer
      The 60th Plastic Surgery Research Council
    • Place of Presentation
      Seattle, Washington USA
    • Year and Date
      2015-05-14 – 2015-05-16
    • Data Source
      KAKENHI-PROJECT-25462808
  • 1.  KAWAI Kenichiro (80423177)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 12 results
  • 2.  KAKIBUCHI Masao (50252664)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 12 results
  • 3.  NISHIMOTO Soh (30281124)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 12 results
  • 4.  藤原 敏宏 (00423179)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 5.  FUJITA Kazutoshi (40461066)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 6.  曽束 洋平 (40437413)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  久保 盾貴 (00362707)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  中島 考陽 (00987951)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results

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