TAKIYOSHI Noriko 滝吉典子

Researcher Number	30568895
Affiliation (based on the past Project Information) *help	2016 – 2017: 弘前大学, 医学部附属病院, 助教 2014: 弘前大学, 医学部附属病院, 助教 2013: 弘前大学, 医学(系)研究科(研究院), 研究員 2010 – 2012: 弘前大学, 医学部附属病院, 助手 2011: 弘前大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator パピヨン・ルフェーブル症候群 / カテプシンC / セリンプロテアーゼ / 過角化 / 掌蹠角化 / 手足症候群 / 外的刺激 / acanthosis / hyperkeratosis / inflamation … More / cathepsin C / セリンプレテアーゼ / 掌蹠 / 遺伝性疾患 / 角化 / メラノサイト / 表皮細胞 / 癌 / 遺伝子変異 … More Except Principal Investigator 抗体 / 唾液 / クロマト / 免疫 / 類天疱瘡 / ベッドサイド / ベットサイド / イムノクロマトグラフィー / ELISA / 水疱 / 皮膚 / 遺伝子 / 自己免疫 Less

Immunochromatographic method using the salive for rapid diagnosis of bullous pemhigoid
- Principal Investigator
  
  SAWAMURA Daisuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Hirosaki University
Research on the pathogenesis of hand-foot syndrome focosing on cathepsin CPrincipal Investigator
- Principal Investigator
  
  TAKIYOSHI Noriko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Hirosaki University
Factors inhibit serine protease activity and echance epidermal differentiation in Papillon-Lefevre syndromePrincipal Investigator
- Principal Investigator
  
  TAKIYOSHI Noriko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Hirosaki University
Serine proteinase dysfunction in keratinocyte of Papillon-Lefevre syndromePrincipal Investigator
- Principal Investigator
  
  TAKIYOSHI Noriko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Hirosaki University

All 2017 2016 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Juvenile temporal arteritis with eosinophilia associated with systemic sclerosis.2017
- Author(s)
  Matsui A, Kaneko T, Takiyoshi N, Rokunohe D, Nakano H, Sawamura D.
- Journal Title
  
  J Dermatol.
  
  Volume: 44 Issue: 3
- DOI
  10.1111/1346-8138.13508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461674, KAKENHI-PROJECT-16K19702
[Journal Article] 優性栄養障害型表皮水疱症（痒疹型）VS結節性痒疹2016
- Author(s)
  赤坂英二郎、滝吉典子、中野　創、澤村大輔
- Journal Title
  
  Visual Dermatol,
  
  Volume: 15 Pages: 924-926
- Data Source
  KAKENHI-PROJECT-16K19702
[Journal Article] Papillon- Lefevre症候群2016
- Author(s)
  滝吉典子
- Journal Title
  
  小児科診療
  
  Volume: 79(増） Pages: 387-387
- Data Source
  KAKENHI-PROJECT-16K19702
[Journal Article] Usefulness of ultrasonography in the diagnosis of ischemic fasciitis.2016
- Author(s)
  Kaneko T, Rokunohe D, Takiyoshi N, Minakawa S, Nakano H, Sawamura D.
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 41 Issue: 5 Pages: 502-505
- DOI
  10.1111/ced.12834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10122, KAKENHI-PROJECT-16K19702
[Journal Article] Elevated levels of circulating immunoglobulin E autoantibodies against BP180 and BP230 in an intractable case of bullous pemphigoid.2016
- Author(s)
  Akasaka E, Hagiwara C, Takiyoshi N, Aizu T, Nakano H, Sawamura D, Ota T
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 84 Issue: 1 Pages: 110-113
- DOI
  10.1016/j.jdermsci.2016.07.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293254, KAKENHI-PROJECT-16K15541, KAKENHI-PROJECT-16K19702
[Journal Article] 点状掌蹠角化症の２家系例2014
- Author(s)
  赤坂英二郎、中野　創、滝吉典子、澤村大輔
- Journal Title
  
  第28回角化症研究会記録集
  
  Volume: 28 Pages: 78-81
- Data Source
  KAKENHI-PROJECT-24591621
[Journal Article] Papillon-Lefèvre　syndrome:　Impact　of　cathepsin　C　activation　on　the　phenotypic expression.2013
- Author(s)
  Takiyoshi N, Nakano H, Sawamura D
- Journal Title
  
  Hirosaki Med J
  
  Volume: 64 Pages: 65-70
- NAID
  110009614131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591621
[Journal Article] Buschke-Ollendorff syndrome associated with hypertrophic scar formation : a possible role for LEMD3 mutation2012
- Author(s)
  Korekawa A, Nakano H, Toyomaki Y, Takiyoshi N, Rokunohe D, Akasaka E, Nakajima K, Sawamura D
- Journal Title
  
  Br J Dermatol
  
  Volume: 166 Issue: 4 Pages: 900-903
- DOI
  10.1111/j.1365-2133.2011.10691.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591427, KAKENHI-PROJECT-22791048, KAKENHI-PROJECT-23390279, KAKENHI-PROJECT-23791247
[Journal Article] Diffuse and focal palmoplantar keratoderma can be caused by a keratin 6c mutation2011
- Author(s)
  Akasaka E, Nakano H, Nakano A, Toyomaki Y, Takiyoshi N, Rokunohe D, Nishikawa Y, Korekawa A, Matsuzaki Y, Mitsuhashi Y, Sawamura D
- Journal Title
  
  Br J Dermatol
  
  Volume: 165(6) Issue: 6 Pages: 1290-1292
- DOI
  10.1111/j.1365-2133.2011.10552.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591427, KAKENHI-PROJECT-22791048, KAKENHI-PROJECT-23591611, KAKENHI-PROJECT-23659540
[Journal Article] Epidermolysis bullosa pruriginosa with marked phenotypic heterogeneity caused by a recurrent glycine substitution : incomplete penetrance or a latent case?2011
- Author(s)
  Takiyoshi N, Nakano H, Sawamura D
- Journal Title
  
  J Dermatol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791048
[Journal Article] Epidermolysis bullosa pruriginosa with marked phenotypic heterogeneity caused by a recurrent glycine substitution : incomplete penetrance or a latent case?2011
- Author(s)
  Takiyoshi N, Nakano H, et al.
- Journal Title
  
  The Journal of Dermatology
  
  Volume: (Epub) Issue: 8 Pages: 718-719
- DOI
  10.1111/j.1346-8138.2011.01392.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791048
[Presentation] 当科における過去12年の無症候性多発性基底細胞癌の統計2017
- Author(s)
  滝吉典子、金子高英、中野　創、澤村大輔
- Organizer
  第69回日本皮膚科学会西部支部学術大会
- Data Source
  KAKENHI-PROJECT-16K19702
[Presentation] Multiple miliary osteoma of the face2017
- Author(s)
  滝吉典子、金子高英、中野　創、澤村大輔
- Organizer
  日本皮膚科学会東北六県合同地方会第378 回例会
- Data Source
  KAKENHI-PROJECT-16K19702
[Presentation] Miescher母斑上に生じたlentigo maligna melanoma.2016
- Author(s)
  滝吉典子、会津隆幸、萩原千尋、金子高英、中野　創、澤村大輔
- Organizer
  日本皮膚科学会東北六県合同地方会学術大会第374回例会
- Place of Presentation
  仙台サンプラザホテル（宮城県・仙台市）
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-16K19702
[Presentation] BRAF/MEK阻害薬が奏功した進行性悪性黒色腫2016
- Author(s)
  滝吉典子、金子高英、高橋実か、原　憲司、福井智久、是川あゆ美、赤坂英二郎、中野　創、澤村大輔
- Organizer
  日本皮膚科学会青森地方会第376回例会
- Place of Presentation
  ホテル青森（青森県・青森市）
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-16K19702
[Presentation] LIPH遺伝子変異を同定した先天性縮毛症/乏毛症の2例2016
- Author(s)
  滝吉典子、赤坂英二郎、金子高英、中野　創、澤村大輔、野村和夫、平山隆士
- Organizer
  日本皮膚科学会青森地方会第375回例会
- Place of Presentation
  ホテルニューキャッスル（青森県・弘前市）
- Year and Date
  2016-08-28
- Data Source
  KAKENHI-PROJECT-16K19702
[Presentation] Impact of Cathepsin C activity on keratinaization2014
- Author(s)
  滝吉　典子
- Organizer
  表皮細胞研究会
- Place of Presentation
  鹿児島市
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24591621
[Presentation] Papillon-Lefèvre syndrome; five novel mutation of CTSC and functional analyses of a single nucleotide polymorphism.2012
- Author(s)
  Takiyoshi N
- Organizer
  The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okinawa（沖縄県）
- Data Source
  KAKENHI-PROJECT-24591621
[Presentation] カテプシンC遺伝子変異が同定されたPapillon-Lefèvre症候群：本邦4家系の報告2012
- Author(s)
  滝吉　典子
- Organizer
  第19回分子皮膚科学フォーラム
- Place of Presentation
  ホテル青森（青森県）
- Data Source
  KAKENHI-PROJECT-24591621
[Presentation] Papillon-Lefèvre syndrome ; total loss of cathepsin C activity may be required for disease expression．2012
- Author(s)
  Takiyoshi N
- Organizer
  42th Annual Meeting of the European Society for Dermatological Research (ESDR 2012)
- Place of Presentation
  Venice（Italy)
- Data Source
  KAKENHI-PROJECT-24591621
[Presentation] Mutational analyses in Papillon-Lefevre syndrome2011
- Author(s)
  Takiyoshi Noriko
- Organizer
  The 41st Annual Meeting of the European Society for Dermatological Research (ESDR)
- Place of Presentation
  バルセロナ(スペイン)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-22791048
[Presentation] Functional analyses in Papillon-Lefevre syndrome2011
- Author(s)
  滝吉典子
- Organizer
  日本研究皮膚科学会第36回年次学術大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22791048
[Presentation] カテプシンC遺伝子変異が同定されたPapillon-Lefevre症候群の2家系2011
- Author(s)
  滝吉典子
- Organizer
  第26回角化症研究会
- Place of Presentation
  東京商工会議所
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-22791048
[Presentation] カテプシンC遺伝子変異が同定されたPapillon-Lefevre症候群の1家系の報告及び、ケラチノサイト由来細胞におけるカテプシンC発現の検討2010
- Author(s)
  滝吉典子
- Organizer
  第17回分子皮膚科学フォーラム
- Place of Presentation
  ホテルオークラ福岡(福岡市)
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-22791048
[Presentation] Richner-Hanhart症候群；臨床症状と血中チロシン濃度との関係
- Author(s)
  滝吉　典子
- Organizer
  第27回角化症研究会
- Place of Presentation
  東京商工会議所（東京都）
- Data Source
  KAKENHI-PROJECT-24591621

1. NAKANO Hajime (90281922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. SAWAMURA Daisuke (60196334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 会津隆幸 (00400135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松崎康司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 沢村大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
6. 金子高英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 皆川智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKIYOSHI Noriko 滝吉 典子

Research Projects

Research Products

Co-Researchers

Immunochromatographic method using the salive for rapid diagnosis of bullous pemhigoid

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the pathogenesis of hand-foot syndrome focosing on cathepsin CPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Factors inhibit serine protease activity and echance epidermal differentiation in Papillon-Lefevre syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Serine proteinase dysfunction in keratinocyte of Papillon-Lefevre syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Juvenile temporal arteritis with eosinophilia associated with systemic sclerosis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 優性栄養障害型表皮水疱症（痒疹型）VS結節性痒疹2016

Author(s)

Journal Title

Data Source

[Journal Article] Papillon- Lefevre症候群2016

Author(s)

Journal Title

Data Source

[Journal Article] Usefulness of ultrasonography in the diagnosis of ischemic fasciitis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated levels of circulating immunoglobulin E autoantibodies against BP180 and BP230 in an intractable case of bullous pemphigoid.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 点状掌蹠角化症の２家系例2014

Author(s)

Journal Title

Data Source

[Journal Article] Papillon-Lefèvre syndrome: Impact of cathepsin C activation on the phenotypic expression.2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Buschke-Ollendorff syndrome associated with hypertrophic scar formation : a possible role for LEMD3 mutation2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diffuse and focal palmoplantar keratoderma can be caused by a keratin 6c mutation2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epidermolysis bullosa pruriginosa with marked phenotypic heterogeneity caused by a recurrent glycine substitution : incomplete penetrance or a latent case?2011

Author(s)

Journal Title

Data Source

[Journal Article] Epidermolysis bullosa pruriginosa with marked phenotypic heterogeneity caused by a recurrent glycine substitution : incomplete penetrance or a latent case?2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] 当科における過去12年の無症候性多発性 基底細胞癌の統計2017

TAKIYOSHI Noriko 滝吉典子

[Journal Article] Papillon-Lefèvre　syndrome:　Impact　of　cathepsin　C　activation　on　the　phenotypic expression.2013

[Presentation] 当科における過去12年の無症候性多発性基底細胞癌の統計2017