Takagi Naoyuki 高木尚之

Researcher Number	30569471
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 非常勤講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 東北大学, 医学系研究科, 非常勤講師 2021: 東北大学, 医学系研究科, 講師 2017 – 2020: 東北大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery Except Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 58050:Fundamental of nursing-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator バイオフィルム / シリコンインプラント / 被膜拘縮 / 乳房再建 / シリコン人工乳房 / インプラント / BIA-ALCL / 人工乳房 / 慢性炎症 / 被膜恐縮 … More / ティッシュエキスパンダー / 人工物再建 / 異物反応 / 慢性潰瘍 / 創傷治癒学 / 慢性創傷 / 創傷治癒 … More Except Principal Investigator 創傷治癒 / 慢性創傷 / 好中球 / 難治性皮膚潰瘍 / C型レクチン受容体 / 感染 / 糖尿病性足壊疽 / 炎症 / 免疫 / ネトーシス (NETosis) / 創傷ケア / 好中球細胞外トラップ / 血管新生 / 創傷治癒促進 / エンドトキシン / 細胞毒性 / 抗菌作用 / 創傷被覆材 / 難治性潰瘍 / 糖尿病性足潰瘍 / プロタミン / 皮膚潰瘍 / ナノ型乳酸菌 / デフィブラーゼ / バトロキソビン / 乳酸菌 / 腸管免疫 / 皮膚-腸管ネットワーク / 褥瘡 / 糖尿病 / IFN-γ / 肝臓 / NKT細胞 / クオラムセンシング機構 / クオラムセンシング / Biofilm / Dectin-1 / C型レクチン受容体 (CLRs) / 免疫療法 / Dectin-2 / Dectin（デクチン）-2 / ネトーシス / NETs / 好中球エラスターゼ / NETosis（ネトーシス） Less

Snake venom heals wounds -Inhibition of NETs by batroxobin and induction of CD34positive cells-
- Principal Investigator
  
  福士彩記子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Analysis of wound healing responses through skin-intestine networks
- Principal Investigator
  
  Kanno Emi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Tohoku University
Development of protamine-containing wound dressing for diabetic foot gangrene
- Principal Investigator
  
  Umeyama Hirokatsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Elucidation of Chronic Inflammatory Mechanisms and Development of Control Methods Focusing on Biofilm Formation on Silicon Artificial BreastPrincipal Investigator
- Principal Investigator
  
  Takagi Naoyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Development of Novel Universal Wound Care by Inhibition of "Neutrophil Extracellular Trap" for Chronic Wounds
- Principal Investigator
  
  Tanno Hiromasa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Tohoku University
The crosstalk between bacterial communities and biofilm formation
- Principal Investigator
  
  Shimodera Saeko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Elucidation of the mechanism and control of capsular contracture after breast reconstruction after breast reconstructionPrincipal Investigator
- Principal Investigator
  
  Takagi Naoyuki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Development of immunotherapy through C-type lectin receptors for chronic wounds
- Principal Investigator
  
  TACHI Masahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Contribution of invariant natural killer T cells and IFN-gamma to neutrophilic inflammation in skin wounds
- Principal Investigator
  
  Kanno Emi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tohoku University
Development of wound care for regulating inflammatory responses using nano-type lactic acid bacteria
- Principal Investigator
  
  Kanno Emi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Tohoku University
Contribution of C-type lectin receptor-mediated signaling to neutrophil extracellular traps in skin ulcers
- Principal Investigator
  
  Akiko Yano
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Involvement of NETosis on the diabetic ulcers and development of novel wound care
- Principal Investigator
  
  Tachi Masahiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
Elucidation of environment in wound with biofilms and development of efficient therapiesPrincipal Investigator
- Principal Investigator
  
  Takagi Naoyuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Tohoku University

All 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Topical Administration of Heat-Killed Enterococcus faecalis Strain KH2 Promotes Re-Epithelialization and Granulation Tissue Formation during Skin Wound-Healing2021
- Author(s)
  Tanno Hiromasa、Kanno Emi、Kurosaka Shiho、Oikawa Yukari、Watanabe Takumi、Sato Ko、Kasamatsu Jun、Miyasaka Tomomitsu、Ishi Shinyo、Shoji Miki、Takagi Naoyuki、Imai Yoshimichi、Ishii Keiko、Tachi Masahiro、Kawakami Kazuyoshi
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 11 Pages: 1520-1520
- DOI
  10.3390/biomedicines9111520
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03918, KAKENHI-PROJECT-21K10598
[Journal Article] Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses2021
- Author(s)
  Yamaguchi Kenji、Kanno Emi、Tanno Hiromasa、Sasaki Ayako、Kitai Yuki、Miura Takayuki、Takagi Naoyuki、Shoji Miki、Kasamatsu Jun、Sato Ko、Sato Yuka、Niiyama Momoko、Goto Yuka、Ishii Keiko、Imai Yoshimichi、Saijo Shinobu、Iwakura Yoichiro、Tachi Masahiro、Kawakami Kazuyoshi
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 141 Issue: 1 Pages: 164-176
- DOI
  10.1016/j.jid.2020.04.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-18K09473, KAKENHI-PROJECT-19K19494, KAKENHI-PROJECT-19H03812, KAKENHI-PROJECT-21K07063
[Journal Article] Dectin-2-Mediated Signaling Leads to Delayed Skin Wound Healing through Enhanced Neutrophilic Inflammatory Response and Neutrophil Extracellular Trap Formation.2019
- Author(s)
  Miura T, Kawakami K, Kanno E, Tanno H, Tada H, Sato N, Masaki A, Yokoyama R, Kawamura K, Kitai Y, Takagi N, Yamaguchi K, Yamaguchi N, Kyo Y, Ishii K, Imai Y, Saijo S, Iwakura Y, Tachi M.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 139(3) Issue: 3 Pages: 702-711
- DOI
  10.1016/j.jid.2018.10.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09473, KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K11909, KAKENHI-PROJECT-17K19710, KAKENHI-PROJECT-17K17393, KAKENHI-PROJECT-19K10143, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16K11824
[Journal Article] Defect of interferon γ leads to impaired wound healing through prolonged neutrophilic inflammatory response and enhanced MMP-2 activation.2019
- Author(s)
  Kanno E, Tanno H, Masaki A, Sasaki A, Sato N, Goto M, Shisai M, Yamaguchi K, Takagi N, Shoji M, Kitai Y, Sato K, Kasamatsu J, Ishii K, Miyasaka T, Kawakami K, Imai Y, Iwakura Y, Maruyama R, Tachi M, Kawakami K.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 20(22) Issue: 22 Pages: 5657-5657
- DOI
  10.3390/ijms20225657
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17913, KAKENHI-PROJECT-19K19494, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-19K22649
[Journal Article] Experimental Wound Ischemia Does Not Promote Pseudomonas aeruginosa Biofilm Formation2018
- Author(s)
  Emi Kannno, Naoyuki Takagi
- Journal Title
  
  Journal of Dermatology and Dermatologic Surgery
  
  Volume: 22 Pages: 68-71
- Open Access
- Data Source
  KAKENHI-PROJECT-17K17009
[Journal Article] Contribution of CARD9-mediated signaling to wound healing in skin2017
- Author(s)
  Emi Kanno, Kazuyoshi Kawakami, Hiromasa Tanno, Aiko Suziki, Noriko Sato, Airi Masaki, Ayano Imamura, Naoyuki Takagi, Takayuki Miura, Hideki Yamamoto, Keiko Ishii, Hiromitsu Hara, Yoshimichi Imai, Ryoko Maruyama, Masahiro Tachi
- Journal Title
  
  Experimental Dermatology
  
  Volume: 26 Issue: 11 Pages: 1097-1104
- DOI
  10.1111/exd.13389
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11909, KAKENHI-PROJECT-17K12530, KAKENHI-PROJECT-17K17009, KAKENHI-PROJECT-16K15744
[Presentation] 皮膚創傷治癒におけるDectin-1，2の役割とNETs形成との関連2019
- Author(s)
  山口賢次，川上和義，菅野恵美，佐々木綾子，庄司未樹，三浦孝行，丹野寛大，高木尚之，今井啓道，館正弘
- Organizer
  第49回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-18K09473
[Presentation] 皮膚創傷治癒におけるDectin-1，2の役割とNETs形成との関連2019
- Author(s)
  山口賢次，川上和義，菅野恵美，佐々木綾子，庄司未樹，三浦孝行，丹野寛大，高木尚之，今井啓道，館正弘
- Organizer
  第49回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-19H03812
[Presentation] 皮膚創傷治癒におけるDectin-1、2シグナル活性化の影響の違い.2018
- Author(s)
  山口賢次，川上和義，菅野恵美，丹野寛大，佐々木綾子，三浦考行，高木尚之, 館正弘
- Organizer
  第48回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-17K19710
[Presentation] 皮膚創傷治癒におけるDectin-1、2シグナル活性化の影響の違い2018
- Author(s)
  山口賢次，川上和義，菅野恵美，丹野寛大，佐々木綾子，三浦考行，高木尚之, 館正弘
- Organizer
  第48回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-18K09473
[Presentation] 皮膚創傷におけるDectin-2を介した治癒過程およびNETosisの制御2017
- Author(s)
  三浦考行，川上和義, 菅野恵美，丹野寛大，多田浩之, 佐藤紀子，正木愛梨，高木尚之, 山口賢次, 石井恵子, 館正弘
- Organizer
  第47回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-17K19710

1. KANNO Emi (10431595)

# of Collaborated Projects: 12 results

# of Collaborated Products: 9 results
2. Tanno Hiromasa (10755664)

# of Collaborated Projects: 10 results

# of Collaborated Products: 8 results
3. Tachi Masahiro (50312004)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
4. KAWAKAMI kazuyoshi (10253973)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
5. 佐藤光 (20832124)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 丸山良子 (10275498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 山口賢次 (70897892)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Akiko Yano (70612224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Shimodera Saeko (10868227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Umeyama Hirokatsu (40770334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 笠松純 (60567345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 福士彩記子 (10747091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 庄司未樹 (90645293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 岩倉洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 宮坂智充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takagi Naoyuki 高木 尚之

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Elucidation of Chronic Inflammatory Mechanisms and Development of Control Methods Focusing on Biofilm Formation on Silicon Artificial BreastPrincipal Investigator

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Elucidation of the mechanism and control of capsular contracture after breast reconstruction after breast reconstructionPrincipal Investigator

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Elucidation of environment in wound with biofilms and development of efficient therapiesPrincipal Investigator

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[Journal Article] Topical Administration of Heat-Killed Enterococcus faecalis Strain KH2 Promotes Re-Epithelialization and Granulation Tissue Formation during Skin Wound-Healing2021

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[Journal Article] Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses2021

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Takagi Naoyuki 高木尚之