Takagi Naoyuki 高木尚之

Researcher Number	30569471
Other IDs
Affiliation (Current)	2022: 東北大学, 医学系研究科, 非常勤講師
Affiliation (based on the past Project Information) *help	2022: 東北大学, 医学系研究科, 非常勤講師 2021: 東北大学, 医学系研究科, 講師 2017 – 2021: 東北大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery Except Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 58050:Fundamental of nursing-related / Surgery related to the biological and sensory functions and related fields / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Medium-sized Section 58:Society medicine, nursing, and related fields
Keywords	Principal Investigator バイオフィルム / 創傷治癒 / 慢性創傷 / 創傷治癒学 / 慢性潰瘍 / 乳房再建 / 被膜拘縮 / 異物反応 / シリコンインプラント / 人工物再建 … More / ティッシュエキスパンダー / 被膜恐縮 / シリコン人工乳房 / 慢性炎症 … More Except Principal Investigator 創傷治癒 / 好中球 / 慢性創傷 / 糖尿病性足壊疽 / 感染 / ネトーシス (NETosis) / 炎症 / C型レクチン受容体 / 難治性皮膚潰瘍 / NETosis（ネトーシス） / 好中球エラスターゼ / NETs / ナノ型乳酸菌 / 皮膚潰瘍 / NKT細胞 / 肝臓 / IFN-γ / 糖尿病 / ネトーシス / Dectin（デクチン）-2 / 免疫療法 / C型レクチン受容体 (CLRs) / Dectin-1 / Dectin-2 / プロタミン / 抗菌作用 / 創傷治癒促進 / 創傷被覆材 / 好中球細胞外トラップ / 創傷ケア / Biofilm / 腸管免疫 / バトロキソビン / デフィブラーゼ Less

Snake venom heals wounds -Inhibition of NETs by batroxobin and induction of CD34positive cells-
- Principal Investigator
  
  福士彩記子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
糖尿病性足壊疽に対する切り札-プロタミン含有創傷被覆材の開発-
- Principal Investigator
  
  梅山広勝
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
シリコン人工乳房へのバイオフィルム形成に注目した慢性炎症機序の解明、制御法の開拓Principal Investigator
- Principal Investigator
  
  高木尚之
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
慢性創傷に対する「好中球細胞外トラップ」阻害によるユニバーサル創傷ケアの開発
- Principal Investigator
  
  丹野寛大
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Tohoku University
飲む褥瘡予防法の確立に向けた、皮膚－腸管ネットワークによる創傷治癒制御機構の解明
- Principal Investigator
  
  菅野恵美
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Tohoku University
Biofilm形成に関わる免疫と細菌間クロストークの解明、新規治療法の開発
- Principal Investigator
  
  下寺佐栄子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
難治性皮膚潰瘍に対する「ナノ型乳酸菌」による炎症制御効果の解明、新規ケア法の開発
- Principal Investigator
  
  菅野恵美
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Tohoku University
Contribution of invariant natural killer T cells and IFN-gamma to neutrophilic inflammation in skin wounds
- Principal Investigator
  
  Kanno Emi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tohoku University
慢性創傷に対する免疫療法の開発～CLRsを介したアクセル・ブレーキ理論の応用～
- Principal Investigator
  
  館正弘
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Elucidation of the mechanism and control of capsular contracture after breast reconstruction after breast reconstructionPrincipal Investigator
- Principal Investigator
  
  Takagi Naoyuki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Contribution of C-type lectin receptor-mediated signaling to neutrophil extracellular traps in skin ulcers
- Principal Investigator
  
  Akiko Yano
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tohoku University
Involvement of NETosis on the diabetic ulcers and development of novel wound care
- Principal Investigator
  
  Tachi Masahiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tohoku University
Elucidation of environment in wound with biofilms and development of efficient therapiesPrincipal Investigator
- Principal Investigator
  
  Takagi Naoyuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Tohoku University

All 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses2021
- Author(s)
  Yamaguchi Kenji、Kanno Emi、Tanno Hiromasa、Sasaki Ayako、Kitai Yuki、Miura Takayuki、Takagi Naoyuki、Shoji Miki、Kasamatsu Jun、Sato Ko、Sato Yuka、Niiyama Momoko、Goto Yuka、Ishii Keiko、Imai Yoshimichi、Saijo Shinobu、Iwakura Yoichiro、Tachi Masahiro、Kawakami Kazuyoshi
- Journal Title
  
  J Invest Dermatol
  
  Volume: 141 Pages: 164-176
- DOI
  10.1016/j.jid.2020.04.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-18K09473, KAKENHI-PROJECT-19K19494
[Journal Article] Dectin-2?Mediated Signaling Leads to Delayed Skin Wound Healing through Enhanced Neutrophilic Inflammatory Response and Neutrophil Extracellular Trap Formation2019
- Author(s)
  Miura T, Kawakami K, Kanno E, Tanno H, Tada H, Sato N, Masaki A, Yokoyama R, Kawamura K, Kitai Y, Takagi N, Yamaguchi K, Yamaguchi N, Kyo Y, Ishii K, Imai Y, Saijo S, Iwakura Y, Tachi M.
- Journal Title
  
  The Journal of investigative dermatology
  
  Volume: 139(3) Pages: 702-711
- DOI
  10.1016/j.jid.2018.10.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09473, KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K11909, KAKENHI-PROJECT-17K19710, KAKENHI-PROJECT-17K17393, KAKENHI-PROJECT-19K10143, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16K11824
[Journal Article] Experimental Wound Ischemia Does Not Promote Pseudomonas aeruginosa Biofilm Formation2018
- Author(s)
  Emi Kannno, Naoyuki Takagi
- Journal Title
  
  Journal of Dermatology and Dermatologic Surgery
  
  Volume: 22 Pages: 68-71
- Open Access
- Data Source
  KAKENHI-PROJECT-17K17009
[Journal Article] Contribution of CARD9-mediated signalling to wound healing in skin2017
- Author(s)
  Emi Kanno, Kazuyoshi Kawakami, Hiromasa Tanno, Aiko Suziki, Noriko Sato, Airi Masaki, Ayano Imamura, Naoyuki Takagi, Takayuki Miura, Hideki Yamamoto, Keiko Ishii, Hiromitsu Hara, Yoshimichi Imai, Ryoko Maruyama, Masahiro Tachi
- Journal Title
  
  Experimental Dermatology
  
  Volume: 26 Pages: 1097-1104
- DOI
  10.1111/exd.13389
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11909, KAKENHI-PROJECT-17K12530, KAKENHI-PROJECT-17K17009, KAKENHI-PROJECT-16K15744
[Presentation] 皮膚創傷治癒におけるDectin-1，2の役割とNETs形成との関連2019
- Author(s)
  山口賢次，川上和義，菅野恵美，佐々木綾子，庄司未樹，三浦孝行，丹野寛大，高木尚之，今井啓道，館正弘
- Organizer
  第49回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-18K09473
[Presentation] 皮膚創傷治癒におけるDectin-1，2の役割とNETs形成との関連2019
- Author(s)
  山口賢次，川上和義，菅野恵美，佐々木綾子，庄司未樹，三浦孝行，丹野寛大，高木尚之，今井啓道，館正弘
- Organizer
  第49回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-19H03812
[Presentation] 皮膚創傷治癒におけるDectin-1、2シグナル活性化の影響の違い.2018
- Author(s)
  山口賢次，川上和義，菅野恵美，丹野寛大，佐々木綾子，三浦考行，高木尚之, 館正弘
- Organizer
  第48回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-17K19710
[Presentation] 皮膚創傷治癒におけるDectin-1、2シグナル活性化の影響の違い2018
- Author(s)
  山口賢次，川上和義，菅野恵美，丹野寛大，佐々木綾子，三浦考行，高木尚之, 館正弘
- Organizer
  第48回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-18K09473
[Presentation] 皮膚創傷におけるDectin-2を介した治癒過程およびNETosisの制御2017
- Author(s)
  三浦考行，川上和義, 菅野恵美，丹野寛大，多田浩之, 佐藤紀子，正木愛梨，高木尚之, 山口賢次, 石井恵子, 館正弘
- Organizer
  第47回日本創傷治癒学会
- Data Source
  KAKENHI-PROJECT-17K19710

1. KANNO Emi (10431595)

# of Collaborated Projects: 12 results

# of Collaborated Products: 9 results
2. 丹野寛大 (10755664)

# of Collaborated Projects: 10 results

# of Collaborated Products: 8 results
3. Tachi Masahiro (50312004)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
4. KAWAKAMI kazuyoshi (10253973)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
5. 丸山良子 (10275498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 佐藤光 (20832124)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 山口賢次 (70897892)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Akiko Yano (70612224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 笠松純 (60567345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 梅山広勝 (40770334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 下寺佐栄子 (10868227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 福士彩記子 (10747091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 庄司未樹 (90645293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TADA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 吉川慧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 岩倉洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 西城忍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takagi Naoyuki 高木 尚之

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シリコン人工乳房へのバイオフィルム形成に注目した慢性炎症機序の解明、制御法の開拓Principal Investigator

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Elucidation of the mechanism and control of capsular contracture after breast reconstruction after breast reconstructionPrincipal Investigator

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Elucidation of environment in wound with biofilms and development of efficient therapiesPrincipal Investigator

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[Journal Article] Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses2021

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[Journal Article] Dectin-2?Mediated Signaling Leads to Delayed Skin Wound Healing through Enhanced Neutrophilic Inflammatory Response and Neutrophil Extracellular Trap Formation2019

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Takagi Naoyuki 高木尚之