hiyoshi yukiharu 日吉幸晴

… Alternative Names

Hiyoshi Yukiharu 日吉幸晴

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Researcher Number	30573612
Other IDs
Affiliation (Current)	2025: 熊本大学, 病院, 助教
Affiliation (based on the past Project Information) *help	2025: 熊本大学, 病院, 助教 2020 – 2022: 公益財団法人がん研究会, 有明病院大腸外科, 副医長 2019: 熊本大学, 病院, 助教 2018: 熊本大学, 医学部附属病院, 助教 2017: 熊本大学, 医学部附属病院, 診療助手 … More 2016: 公益財団法人がん研究会, 有明病院消化器外科, 医員 2015: 公益財団法人がん研究会, その他部局等, その他 2014: 熊本大学, 医学部附属病院, 特任助教 2013: 九州大学, 医学(系)研究科(研究院), 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Digestive surgery / General surgery Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator microarray / microRNA / 直腸癌 / 血清 / real-time PCR / 側方リンパ節 / miRNA / CK19 / 手術 / 放射線化学療法 … More / OSNA / 微小転移 / リンパ節転移 / PCR / CRT / miR-143 / 効果予測 / 化学放射線療法 / lncRNA / lincRNA / 組織 / non-coding RNA / 消化器癌 … More Except Principal Investigator Predictive marker / 治療効果予測 / 化学療法 / AI / 機械学習 / CTテクスチャ解析 / 肝転移 / 切除不能大腸癌 / バイオマーカー / スタチン / 膵癌 / 難治癌 / Wnt inhibitor / simvastatin / BRAF / K-ras / TGFβ経路 / Wnt経路 / EGFR経路 / スタチンバイオマーカー / 薬物療法 / Wnt阻害薬 / シンバスタチン / BRAF遺伝子変異 / KRAS遺伝子変異 / 大腸癌 Less

空間トランスクリプトームとリキッドバイオプシーによる直腸癌新規バイオマーカー探索Principal Investigator
- Principal Investigator
  
  日吉幸晴
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
CT radiomics-based machine learning predicts objective response of first-line chemotherapy in patients with colorectal liver metastases.
- Principal Investigator
  
  Miyamoto Yuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
Detection of lymph node micrometastasis in rectal cancerPrincipal Investigator
- Principal Investigator
  
  HIYOSHI Yukiharu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
  Kumamoto University
Development of statin-based therapies for colorectal cancer along with biomarkers
- Principal Investigator
  
  Ishikawa Shinji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Identification of serum microRNA as novel response predictor of preoperative CRT for locally advanced recta cancerPrincipal Investigator
- Principal Investigator
  
  HIYOSHI Yukiharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
  Japanese Foundation for Cancer Research
Comprehensive analysis of expression and function of lincRNA in gastroenterological cancerPrincipal Investigator
- Principal Investigator
  
  Hiyoshi Yukiharu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Japanese Foundation for Cancer Research
  Kumamoto University
  Kyushu University

All 2022 2021 2020 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Non-operative management after chemoradiotherapy plus consolidation or sandwich (induction with bevacizumab and consolidation) chemotherapy in patients with locally advanced rectal cancer: a multicentre, randomised phase II trial (NOMINATE trial)2022
- Author(s)
  Akiyoshi Takashi、Shinozaki Eiji、Taguchi Senzo、Chino Akiko、Hiratsuka Makiko、Tominaga Tetsuro、Nonaka Takashi、Toda Shigeo、Matoba Shuichiro、Matsui Shimpei、Okabayashi Koji、Mukai Toshiki、Hiyoshi Yukiharu et al.
- Journal Title
  
  BMJ Open
  
  Volume: 12 Issue: 3 Pages: e055140-e055140
- DOI
  10.1136/bmjopen-2021-055140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07735, KAKENHI-PROJECT-22K08881, KAKENHI-PROJECT-20K09022
[Journal Article] Treatment outcome of laparoscopic surgery after self-expandable metallic stent insertion for obstructive colorectal cancer2021
- Author(s)
  Hiyoshi Yukiharu、Mukai Toshiki、Nagasaki Toshiya、Yamaguchi Tomohiro、Nagayama Satoshi、Akiyoshi Takashi、Sasaki Takashi、Saito Shoichi、Fukunaga Yosuke
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 11 Pages: 2029-2036
- DOI
  10.1007/s10147-021-01990-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07735, KAKENHI-PROJECT-20K09022
[Journal Article] The advantage of one‐step nucleic acid amplification for the diagnosis of lymph node metastasis in colorectal cancer patients2020
- Author(s)
  Hiyoshi Yukiharu、Akiyoshi Takashi、Fukunaga Yosuke
- Journal Title
  
  Annals of Gastroenterological Surgery
  
  Volume: 5 Issue: 1 Pages: 60-66
- DOI
  10.1002/ags3.12392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07735, KAKENHI-PROJECT-20K09022, KAKENHI-PROJECT-18K08664
[Journal Article] Late Recurrence After Radical Resection of Esophageal Cancer2016
- Author(s)
  Yukiharu Hiyoshi, Naoya Yoshida, Hideo Baba et al.
- Journal Title
  
  World Journal of Surgery
  
  Volume: 40(4) Issue: 4 Pages: 913-20
- DOI
  10.1007/s00268-015-3334-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461984
[Journal Article] Increased microRNA-34b and -34c predominantly expressed in stromal tissues is associated with poor prognosis in human colon cancer2015
- Author(s)
  Yukiharu Hiyoshi, Schetter Aaron, Harris Curtis et al.
- Journal Title
  
  PLoS One
  
  Volume: 10(4) Issue: 4 Pages: e0124899-e0124899
- DOI
  10.1371/journal.pone.0124899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461984
[Journal Article] Clinical significance of surgical resection for the recurrence of esophageal cancer after radical esophagectomy.2015
- Author(s)
  Hiyoshi Y, Morita M, Kawano H, Otsu H, Ando K, Ito S, Miyamoto Y, Sakamoto Y, Saeki H, Oki E, Ikeda T, Baba H, Maehara Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 22 Issue: 1 Pages: 206-240
- DOI
  10.1245/s10434-014-3970-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-25461984, KAKENHI-PROJECT-15K10127
[Journal Article] Autophagic degradation of the inhibitory p53 isoform Delta133p53alpha as a regulatory mechanism for p53-mediated senescence2014
- Author(s)
  Horikawa I, Fujita K, Jenkins LM, Hiyoshi Y, Mondal AM, Vojtesek B, Lane DP, Appella E, Harris CC
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 4706-4706
- DOI
  10.1038/ncomms5706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461984
[Presentation] 右側結腸癌に対する腹腔鏡下手術の治療成績: Inferior vs Medial approach2022
- Author(s)
  日吉幸晴、向井俊貴、長嵜寿矢、山口智弘、秋吉高志、福長洋介
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K07735
[Presentation] 脾彎曲部癌に対する腹腔鏡下結腸切除術2021
- Author(s)
  日吉幸晴、向井俊貴、長嵜寿矢、山口智弘、長山　聡、秋吉高志、福長洋介
- Organizer
  第76回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-19K07735
[Presentation] 閉塞性大腸癌に対するステント留置後腹腔鏡手術の治療成績2021
- Author(s)
  日吉幸晴、向井俊貴、長嵜寿矢、山口智弘、秋吉高志、福長洋介
- Organizer
  第34回日本内視鏡外科学会総会
- Data Source
  KAKENHI-PROJECT-19K07735
[Presentation] 高齢の大腸癌肝転移患者における Geriatric Nutritional Risk index（GNRI）の予後予測指標としての有用性2020
- Author(s)
  秋山貴彦、宮本裕士、坂本悠樹、大徳暢哉、徳永竜馬、江藤弘二郎、日吉幸晴、長井洋平、岩槻政晃、岩上志朗、馬場祥史、吉田直矢、馬場秀夫
- Organizer
  第75回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07702
[Presentation] 肝外転移を伴う大腸癌肝転移に対するConversion surgeryの可能性2020
- Author(s)
  宮本裕士、日吉幸晴、徳永竜馬、秋山貴彦、大徳暢哉、坂本悠樹、吉田直矢、馬場秀夫
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K07702
[Presentation] 原発巣の局在からみた大腸癌肝転移に対する術前化学療法の意義2020
- Author(s)
  松石梢、今井克憲、武末亨、丸野正敬、山尾宣暢、東孝暁、山村謙介、日吉幸春、宮本裕士、山下洋市、馬場秀夫
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K07702
[Presentation] 直腸癌術前CRTにおける効果予測マーカーとしての血清miR-143の有用性2017
- Author(s)
  日吉幸晴、秋吉高志、徳永竜馬、市原明子、牛込創、鈴木紳祐、南宏典、宮成淳、村橋賢、福岡宏倫、武田泰裕、三城弥範、小倉淳司、長嵜寿矢、小西毅、藤本佳也、長山聡、福長洋介、上野雅資
- Organizer
  第117回　日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10557
[Presentation] Serum microRNAs as a predictive marker for pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients2016
- Author(s)
  Yukiharu Hiyoshi
- Organizer
  European Society of Coloproctology
- Place of Presentation
  Milan, Itary
- Year and Date
  2016-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10557
[Presentation] 食道癌切除例における女性食道癌の特徴2015
- Author(s)
  日吉幸晴、吉田直矢、馬場秀夫
- Organizer
  第69回　日本食道学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-25461984
[Presentation] 食道癌切除後早期再発、晩期再発規定因子の解析2015
- Author(s)
  日吉幸晴、吉田直矢、馬場秀夫
- Organizer
  第115回　日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25461984
[Presentation] 食道扁平上皮癌に対する術前DCF療法の効果予測因子の検討2015
- Author(s)
  日吉幸晴、吉田直矢、馬場秀夫
- Organizer
  第70回　日本消化器外科学会総会
- Place of Presentation
  浜松
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-25461984

1. Miyamoto Yuji (80551259)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 今村裕 (70583045)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 清住雄希 (30827324)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 徳永竜馬 (20594881)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. WATANABE Masayuki (80254639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Ishikawa Shinji (80419639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 石本崇胤 (00594889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 別府透 (70301372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 秋吉高志 (50625598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 宮田辰徳 (80594887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中浦猛 (90437913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 森田勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 佐伯浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 沖英次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

hiyoshi yukiharu 日吉 幸晴

Hiyoshi Yukiharu 日吉 幸晴

Research Projects

Research Products

Co-Researchers

空間トランスクリプトームとリキッドバイオプシーによる直腸癌新規バイオマーカー探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CT radiomics-based machine learning predicts objective response of first-line chemotherapy in patients with colorectal liver metastases.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Detection of lymph node micrometastasis in rectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of statin-based therapies for colorectal cancer along with biomarkers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of serum microRNA as novel response predictor of preoperative CRT for locally advanced recta cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of expression and function of lincRNA in gastroenterological cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Non-operative management after chemoradiotherapy plus consolidation or sandwich (induction with bevacizumab and consolidation) chemotherapy in patients with locally advanced rectal cancer: a multicentre, randomised phase II trial (NOMINATE trial)2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Treatment outcome of laparoscopic surgery after self-expandable metallic stent insertion for obstructive colorectal cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The advantage of one‐step nucleic acid amplification for the diagnosis of lymph node metastasis in colorectal cancer patients2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Late Recurrence After Radical Resection of Esophageal Cancer2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased microRNA-34b and -34c predominantly expressed in stromal tissues is associated with poor prognosis in human colon cancer2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of surgical resection for the recurrence of esophageal cancer after radical esophagectomy.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autophagic degradation of the inhibitory p53 isoform Delta133p53alpha as a regulatory mechanism for p53-mediated senescence2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 右側結腸癌に対する腹腔鏡下手術の治療成績: Inferior vs Medial approach2022

Author(s)

Organizer

Data Source

hiyoshi yukiharu 日吉幸晴

Hiyoshi Yukiharu 日吉幸晴