Nakajima Takero 中嶌岳郎

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NAKAJIMA Takero 中嶌岳郎

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Researcher Number	30581011
Other IDs
Affiliation (Current)	2025: 信州大学, 学術研究院医学系, 助教
Affiliation (based on the past Project Information) *help	2015 – 2023: 信州大学, 学術研究院医学系, 助教 2011 – 2013: 信州大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / General medical chemistry / Medical pharmacy Except Principal Investigator Basic Section 38050:Food sciences-related / Food science / Experimental pathology
Keywords	Principal Investigator スルファチド / 老化促進モデルマウス / 硫酸化糖脂質 / 老化 / PPARα / 生体分子 / 酸化ストレス / 分子薬理学 / 臨床用量 / ミトコンドリアβ酸化 / 脂肪酸代謝 / 脂質代謝 … More Except Principal Investigator … More 血圧 / テレメトリー法 / 神経活動 / 機能性食品 / 抗ストレス / 乳酸発酵 / 発酵食品 / ex vivo / in vivo / 血管 / 相乗効果 / フラグメントペプチド / 組織蓄積 / ペプチド / ACE阻害 / 栄養学 / 病理学 / 脂質 / 肝臓病学 / 疾患モデル動物 / 腸管・肝臓連関 / マイクロアレイ解析 / CD44 / コレステロール毒性 / メタボロミクス / 核内受容体 / 非アルコール性脂肪肝炎 Less

The study on novel brain aging mechanisms related to brain-specific lipids and development of preventive methodsPrincipal Investigator
- Principal Investigator
  
  中嶌岳郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Shinshu University
Effect of anti-stress ingredients on rat endocrine system via nerve
- Principal Investigator
  
  Nakamura Kozo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Shinshu University
Evaluating the pathogenesis of non-alcoholic steatohepatitis from the viewpoint of xenobiotic metabolism
- Principal Investigator
  
  TANAKA Naoki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Shinshu University
Studies on a novel oxidative stress-reducing effect resulting from generation/excretion of sulfated glycolipidsPrincipal Investigator
- Principal Investigator
  
  Nakajima Takero
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Shinshu University
Clarification of the blood pressure lowering mechanism of novel peptides identified from fermented buckwheat sprouts
- Principal Investigator
  
  NAKAMURA Kozo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shinshu University
Studies on molecular mechanisms of PPARalpha-independent triglyceride-lowering effects of fibrate drugsPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Takero
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Shinshu University

All 2023 2022 2021 2017 2016

All Journal Article

[Journal Article] Establishment of Novel Mouse Model of Dietary NASH Rapidly Progressing into Liver Cirrhosis and Tumors.2023
- Author(s)
  Zheng Q, Kawaguchi M, Mikami H, Diao P, Zhang X, Zhang Z, Nakajima T, Iwadare T, Kimura T, Nakayama J, and Tanaka N
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 14 Pages: 3744-3744
- DOI
  10.3390/cancers15143744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11618
[Journal Article] 多機能性分子・硫酸化糖脂質の機能と制御2023
- Author(s)
  中嶌岳郎、田中直樹
- Journal Title
  
  信州医学雑誌
  
  Volume: 71 Pages: 137-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11618
[Journal Article] Serum sulfatide level is associated with severe systemic vasculitis with kidney involvement.2023
- Author(s)
  Aomura D, Harada M, Nakajima T, Nimura T, Yamaka K, Yamada Y, Hashimoto K, Tanaka N, Kamijo Y
- Journal Title
  
  Front. Immunol.
  
  Volume: 14 Pages: 1271741-1271741
- DOI
  10.3389/fimmu.2023.1271741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11618
[Journal Article] Serum Sulfatide Levels as a Biomarker of Active Glomerular Lesion in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single Center Pilot Study2022
- Author(s)
  Harada Makoto、Nakajima Takero、Yamada Yosuke、Aomura Daiki、Yamaguchi Akinori、Sonoda Kosuke、Tanaka Naoki、Hashimoto Koji、Kamijo Yuji
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 3 Pages: 762-762
- DOI
  10.3390/jcm11030762
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17736, KAKENHI-PROJECT-18K08204, KAKENHI-PROJECT-21K11618
[Journal Article] Clinically Relevant Dose of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα), Lowers Serum Triglyceride Levels by Targeting Hepatic PPARα in Mice2022
- Author(s)
  Zhang Zhe、Diao Pan、Zhang Xuguang、Nakajima Takero、Kimura Takefumi、Tanaka Naoki
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 7 Pages: 1667-1667
- DOI
  10.3390/biomedicines10071667
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11618
[Journal Article] Acidic activated charcoal prevents obesity and insulin resistance in high-fat diet-fed mice.2022
- Author(s)
  Zhang X, Diao P, Yokoyama H, Inoue Y, Tanabe K, Wang X, Hayashi C, Yokoyama T, Zhang Z, Hu X, Nakajima T, Kimura T, Nakayama J, Nakamuta M, and Tanaka N.
- Journal Title
  
  Front. Nutr.
  
  Volume: 9 Pages: 852767-852767
- DOI
  10.3389/fnut.2022.852767
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11618
[Journal Article] Mechanisms of Steatosis-Derived Hepatocarcinogenesis: Lessons from HCV Core Gene Transgenic Mice.2021
- Author(s)
  Diao P, Jia F, Wang X, Hua X, Kimura T, Nakajima T, Aoyama T, Moriya K, Koike K, Tanaka N.
- Journal Title
  
  Engineering
  
  Volume: 7 Issue: 12 Pages: 1797-1805
- DOI
  10.1016/j.eng.2021.08.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11618
[Journal Article] Pemafibrate Protects against Fatty Acid-Induced Nephropathy by Maintaining Renal Fatty Acid Metabolism2021
- Author(s)
  Aomura Daiki、Harada Makoto、Yamada Yosuke、Nakajima Takero、Hashimoto Koji、Tanaka Naoki、Kamijo Yuji
- Journal Title
  
  Metabolites
  
  Volume: 11 Issue: 6 Pages: 372-372
- DOI
  10.3390/metabo11060372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17736, KAKENHI-PROJECT-21K11618
[Journal Article] Decreased Fatty Acid <i>β</i>-Oxidation Is the Main Cause of Fatty Liver Induced by Polyunsaturated Fatty Acid Deficiency in Mice2017
- Author(s)
  Nakajima T, Yang Y, Lu Y, Kamijo Y, Yamada Y, Nakamura K, Koyama M, Yamaguchi S, Sugiyama E, Tanaka N, Aoyama T
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 242 Issue: 3 Pages: 229-239
- DOI
  10.1620/tjem.242.229
- NAID
  130005808367
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08264
[Journal Article] Age-dependent PPARα activation induces hepatic sulfatide accumulation in transgenic mice carrying the hepatitis C virus core gene.2016
- Author(s)
  Tian Y, Yang Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Lu Y, Moriya K, Koike K, Gonzalez FJ, Aoyama T.
- Journal Title
  
  Glycoconj J
  
  Volume: 33 Issue: 6 Pages: 927-936
- DOI
  10.1007/s10719-016-9703-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08264, KAKENHI-PROJECT-16K08616
[Journal Article] Activation of PPARα by Fatty Acid Accumulation Enhances Fatty Acid Degradation and Sulfatide Synthesis.2016
- Author(s)
  Yang Y, Feng Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Aoyama T.
- Journal Title
  
  Tohoku J Exp Med
  
  Volume: 240 Issue: 2 Pages: 113-22
- DOI
  10.1620/tjem.240.113
- NAID
  130005245903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08264

1. TANAKA Naoki (80419374)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. NAKAMURA Kozo (20345763)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. AOYAMA Toshifumi (50231105)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. KAMIJO Yuji (50377636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. KOYAMA Masahiro (00726656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Gonzalez Frank j

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAHASHI Shogo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山田洋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Nakajima Takero 中嶌 岳郎

NAKAJIMA Takero 中嶌 岳郎

Research Projects

Research Products

Co-Researchers

The study on novel brain aging mechanisms related to brain-specific lipids and development of preventive methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of anti-stress ingredients on rat endocrine system via nerve

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluating the pathogenesis of non-alcoholic steatohepatitis from the viewpoint of xenobiotic metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on a novel oxidative stress-reducing effect resulting from generation/excretion of sulfated glycolipidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of the blood pressure lowering mechanism of novel peptides identified from fermented buckwheat sprouts

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on molecular mechanisms of PPARalpha-independent triglyceride-lowering effects of fibrate drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment of Novel Mouse Model of Dietary NASH Rapidly Progressing into Liver Cirrhosis and Tumors.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 多機能性分子・硫酸化糖脂質の機能と制御2023

Author(s)

Journal Title

Data Source

[Journal Article] Serum sulfatide level is associated with severe systemic vasculitis with kidney involvement.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum Sulfatide Levels as a Biomarker of Active Glomerular Lesion in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single Center Pilot Study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinically Relevant Dose of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα), Lowers Serum Triglyceride Levels by Targeting Hepatic PPARα in Mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acidic activated charcoal prevents obesity and insulin resistance in high-fat diet-fed mice.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanisms of Steatosis-Derived Hepatocarcinogenesis: Lessons from HCV Core Gene Transgenic Mice.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pemafibrate Protects against Fatty Acid-Induced Nephropathy by Maintaining Renal Fatty Acid Metabolism2021

Author(s)

Journal Title

DOI

Data Source

Nakajima Takero 中嶌岳郎

NAKAJIMA Takero 中嶌岳郎