TANAKA Tomohisa 田中智久

… Alternative Names

Tanaka Tomohisa 田中智久

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Researcher Number	30585310
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 准教授
Affiliation (based on the past Project Information) *help	2025: 山梨大学, 大学院総合研究部, 准教授 2023: 山梨大学, 大学院総合研究部, 准教授 2019 – 2022: 山梨大学, 大学院総合研究部, 助教 2017: 山梨大学, 大学院総合研究部, 特任助教 2017: 山梨大学, 大学院総合研究部, 助教 … More 2016: 山梨大学, 総合研究部, 特任助教 2014 – 2015: 山梨大学, 総合研究部, 助教 2013: 山梨大学, 医学工学総合研究部, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Veterinary medical science / Virology Except Principal Investigator Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields / Virology
Keywords	Principal Investigator 抗ウイルス薬 / ゲノム複製 / ウイルス / 病原性発現 / スクリーニング / レプリコン / COVID-19 / SARS-CoV-2 / 阻害剤 / エントリー … More / B型肝炎 / HBV / C型肝炎ウイルス / 翻訳開始 / 疫学 / ヘパシウイルス / 非翻訳領域 / 多様性 / 翻訳 / へパシウイルス / 翻訳阻害 / RNA / 感染症 / ナンセンスRNA分解 / 宿主因子 / コロナウイルス / RNA分解 / 病原性 / RNAウイルス … More Except Principal Investigator 感染実験 / 古代DNA / HBVゲノム / 抗ウイルス化合物 / 宿主因子 / 宿主蛋白質 / 抗ウイルス剤 / B型肝炎 / HBV / C型肝炎 / HCV Less

ヘパシウイルス持続感染における自然免疫系の機能解析Principal Investigator
- Principal Investigator
  
  田中智久
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  University of Yamanashi
新型コロナウイルスのnsp1依存性細胞傷害機構の解明とレプリコンモデルへの応用Principal Investigator
- Principal Investigator
  
  田中智久
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  University of Yamanashi
History of humans and pathogens revealed by ancient viral genome analysis
- Principal Investigator
  
  安達登
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields
- Research Institution
  University of Yamanashi
Study on the molecular mechanism of HBV entry and screening of HBV entry inhibitorsPrincipal Investigator
- Principal Investigator
  
  Tanaka Tomohisa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  University of Yamanashi
Analysis of genetic diversity and host-specificity of non-primate hepacivirusPrincipal Investigator
- Principal Investigator
  
  TANAKA Tomohisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  University of Yamanashi
Development of anti-hepatitis virus strategy based on proteomics
- Principal Investigator
  
  MORIISHI Kohji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  University of Yamanashi
The analysis of the mechanism of SARS coronavirus nsp1-mediated mRNA decayPrincipal Investigator
- Principal Investigator
  
  TANAKA Tomohisa
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  University of Yamanashi

All 2023 2021 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Other

[Journal Article] Inhibitory effect of a novel thiazolidinedione derivative on hepatitis B virus entry2021
- Author(s)
  Tanaka Tomohisa、Okuyama-Dobashi Kaori、Motohashi Ryoji、Yokoe Hiromasa、Takahashi Kazunori、Wiriyasermkul Pattama、Kasai Hirotake、Yamashita Atsuya、Maekawa Shinya、Enomoto Nobuyuki、Ryo Akihide、Nagamori Shushi、Tsubuki Masayoshi、Moriishi Kohji
- Journal Title
  
  Antiviral Research
  
  Volume: 194 Pages: 105165-105165
- DOI
  10.1016/j.antiviral.2021.105165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07574, KAKENHI-PROJECT-19K08439, KAKENHI-PROJECT-20K08281, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-21H03365
[Journal Article] Roles of the 5' Untranslated Region of Nonprimate Hepacivirus in Translation Initiation and Viral Replication.2018
- Author(s)
  Tanaka T, Otoguro T, Yamashita A, Kasai H, Fukuhara T, Matsuura Y, Moriishi K.
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 7
- DOI
  10.1128/jvi.01997-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-15K18779
[Journal Article] Seroepidemiology of non-primate hepacivirus (NPHV) in Japanese native horses2018
- Author(s)
  Hayashi Shizuka、Tanaka Tomohisa、Moriishi Kohji、Hirayama Kazuhiro、Yamada Akio、Hotta Kozue
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 80 Issue: 1 Pages: 186-189
- DOI
  10.1292/jvms.17-0527
- NAID
  130006331060
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18779
[Journal Article] Cinnamic acid derivatives inhibit hepatitis C virus replication via the induction of oxidative stress.2017
- Author(s)
  Amano R, Yamashita A, Kasai H, Hori T, Miyasato S, Saito S, Yokoe H, Takahashi K, Tanaka T, Otoguro T, Maekawa S, Enomoto N, Tsubuki M, Moriishi K.
- Journal Title
  
  Antiviral Research
  
  Volume: 145 Pages: 123-130
- DOI
  10.1016/j.antiviral.2017.07.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09348, KAKENHI-PROJECT-16K09349, KAKENHI-PROJECT-15K08493
[Journal Article] Inhibitory effect of presenilin inhibitor LY411575 on maturation of hepatitis C virus core protein, production of the viral particle and expression of host proteins involved in pathogenicity.2016
- Author(s)
  Otoguro T, Tanaka T, Kasai H, Yamashita A, Moriishi K.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 60 Issue: 11 Pages: 740-753
- DOI
  10.1111/1348-0421.12448
- NAID
  40021031203
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-16K09348
[Journal Article] Inhibitory effect of CDK9 inhibitor FIT-039 on hepatitis B virus propagation2016
- Author(s)
  T. Tanaka, K. Okuyama-Dobashi, S. Murakami, W. Chen, T. Okamoto, K. Ueda, T. Hosoya, Y. Matsuura, A. Ryo, Y. Tanaka, M. Hagiwara and K. Moriishi
- Journal Title
  
  Antiviral Research
  
  Volume: 133 Pages: 156164-156164
- DOI
  10.1016/j.antiviral.2016.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-15K08493
[Journal Article] Hepatitis B virus efficiently infects non-adherent hepatoma cells via human sodium taurocholate cotransporting polypeptide.2015
- Author(s)
  Okuyama-Dobashi K, Kasai H, Tanaka T, Yamashita A, Yasumoto J, Chen W, Okamoto T, Maekawa S, Watashi K, Wakita T, Ryo A, Suzuki T, Matsuura Y, Enomoto N, Moriishi K.
- Journal Title
  
  Scientific reports
  
  Volume: 5 Issue: 1 Pages: 17047-17047
- DOI
  10.1038/srep17047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15H04735, KAKENHI-PROJECT-25460985
[Journal Article] Identification of antiviral agents targeting hepatitis B virus promoter from extracts of Indonesian marine organisms by a novel cell-based screening assay.2015
- Author(s)
  Yamashita A, Fujimoto Y, Tamaki M, Setiawan A, Tanaka T, Okuyama-Dobashi K, Kasai H, Watashi K, Wakita T, Toyama M, Baba M, de Voogd NJ, Maekawa S, Enomoto N, Tanaka J, Moriishi K
- Journal Title
  
  Marine Drug
  
  Volume: 13 Issue: 11 Pages: 6759-6773
- DOI
  10.3390/md13116759
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-26350973, KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-25460985
[Presentation] HBV/HCV共感染による宿主代謝・遺伝子発現への影響2023
- Author(s)
  赤池康範、田中智久、山下篤哉、葛西宏威、森石恆司
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19343
[Presentation] 古代ウイルスゲノムが明らかにする後期旧石器時代人の日本列島への渡来ルート2023
- Author(s)
  深澤眞楠、神澤秀明、河合洋介、田中智久、森石恆司、安達　登
- Organizer
  第77回日本人類学会大会
- Data Source
  KAKENHI-PROJECT-22K19343
[Presentation] 大腸菌人工染色体を使ったSARS-CoV-2レプリコンモデルの変異株への適用2023
- Author(s)
  田中智久
- Organizer
  第1回新型コロナウイルス研究集会
- Data Source
  KAKENHI-PROJECT-22K07098
[Presentation] 大腸菌人工染色体を使ったSARS-CoV-2レプリコンモデルの変異株への適用2023
- Author(s)
  田中智久、森石恆司
- Organizer
  第１回新型コロナウイルス研究集会
- Data Source
  KAKENHI-PROJECT-22K07098
[Presentation] HBV Enhancer I-X promoterをターゲットとした抗HBV化合物の同定2021
- Author(s)
  山下　篤哉, 田中　智久, 葛西　宏威, 森石　恆司
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07574
[Presentation] B型および C型肝炎ウイルス感染を許容する培養細胞の樹立2019
- Author(s)
  乙黒光姫、田中智久、葛西宏威、山下篤哉、福原崇介、松浦善治、森石恆司
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07574
[Presentation] HBV感染に関与する cyclin-dependent kinaseの解析2019
- Author(s)
  田中智久、乙黒光姫、葛西宏威、山下篤哉、福原崇介、松浦善治、森石恆司
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07574
[Presentation] HBV core promoter をターゲットとした新規抗HBV化合物4,4'-bis(cyclohexylmethyl)biphenyl-2,2',5,5'-tetraol2019
- Author(s)
  山下篤哉、田中智久、乙黒光姫、葛西宏威、森石恆司
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07574
[Presentation] Involvement of a novel cyclin-dependent kinase in HBV infection2019
- Author(s)
  Tomohisa Tanaka, Kohji Moriishi
- Organizer
  2019 International HBV Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07574
[Presentation] 国内におけるげっ歯類へパシウイルスの遺伝的特徴とへパシウイルス非翻訳領域の機能比較2018
- Author(s)
  田中智久
- Organizer
  第6回肝炎ウイルス研修会
- Data Source
  KAKENHI-PROJECT-15K18779
[Presentation] 5’-terminal stem-loop of equine hepacivirus RNA permits miR-122-independent replication2017
- Author(s)
  Tomohisa Tanaka, Teruhime Otoguro, Kaori Okuyama-Dobashi, Hirotake Kasai, Atsuya Yamashita, Kohji Moriishi
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K18779
[Presentation] Establishment of hepatitis B and C virus co-infection cell line.2017
- Author(s)
  Teruhime Otoguro, Tomohisa Tanaka, Hirotake Kasai, Atsuya Yamashita, Kohji Moriishi
- Organizer
  第65回日本ウイルス学会総会
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] Cross-species compatibility of hepacivirus 5’ untranslated region2016
- Author(s)
  Tomohisa Tanaka, Teruhime Otoguro, Hirotake Kasai, Atsuya Yamashita, Kaori Okuyama-Dobashi and Kohji Moriishi
- Organizer
  日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K18779
[Presentation] Hepatitis C virus infection impairs mono-ubiquitination of histone H2A and activates expression of homeobox genes.2016
- Author(s)
  Kasai H, Tanaka T, Yamashita A, Dobashi-Okuyama K, Moriishi K.
- Organizer
  第64回日本ウイルス学会総会
- Place of Presentation
  札幌コンベンションセンター（札幌白石区）
- Year and Date
  2016-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] Establishment of highly HBV-permissible HepG2 cell line to facilitate screening of antiviral compounds2016
- Author(s)
  Otoguro T, Tanaka T, Chen W, Kasai H, Yamashita A, Okuyama-Dobashi K, Moriishi K
- Organizer
  第64回日本ウイルス学会総会
- Place of Presentation
  札幌コンベンションセンター（札幌白石区）
- Year and Date
  2016-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] Inhibition of HBV propagation by treatment with CDK9 inhibitor FIT-0392016
- Author(s)
  Tanaka T, Okuyama-Dobashi K, Chen W, Okamoto T, Ueda K, Hosaya T, Matsuura Y, Ryo A, Tanaka Y, Hagiwara M and Moriishi K
- Organizer
  2016　International HBV meeting
- Place of Presentation
  ソウル、韓国
- Year and Date
  2016-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] CDK9 inhibitor FIT-039 suppresses HBV propagation2016
- Author(s)
  Moriishi K, Tanaka T, Okuyama-Dobashi K, Chen W, Okamoto T, Ueda K, Hosaya T, Matsuura Y, Ryo A, Tanaka Y, Hagiwara M
- Organizer
  第64回日本ウイルス学会総会
- Place of Presentation
  札幌コンベンションセンター（札幌白石区）
- Year and Date
  2016-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] Cross-species compatibility of hepacivirus 5’ untranslated region2016
- Author(s)
  Tanaka T, Otoguro T, Kasai H, Yamashita A, Okuyama-Dobashi K, Moriishi K
- Organizer
  第64回日本ウイルス学会総会
- Place of Presentation
  札幌コンベンションセンター（札幌白石区）
- Year and Date
  2016-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] Functional homology of hepacivirus 5’ UTRs in IRES activity and replication2016
- Author(s)
  Tomohisa Tanaka, Teruhime Otoguro, Atsuya Yamashita, Hirotake Kasai, and Kohji Moriishi
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都国際会館（京都府・京都市）
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18779
[Presentation] Characterization of the IRES activity in equine hepacivirus 5’UTR2015
- Author(s)
  Tomohisa Tanaka, Wenjia Chen, Teruhime Otoguro, Hirotake Kasai, Atsuya Yamashita, Kohji Moriishi
- Organizer
  日本ウイルス学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] ウマヘパシウイルスが有するIRES活性の特徴2015
- Author(s)
  田中智久、陳文家、乙黒光姫、葛西宏威、山下篤哉、森石恆司
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡県・福岡市
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K18779
[Presentation] プレセニリン阻害剤のC型肝炎ウイルス増殖抑制効果の検討2015
- Author(s)
  乙黒光姫、田中智久、葛西宏威、山下篤哉、森石恆司
- Organizer
  日本ウイルス学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] Characterization of equine hepacivirus 5’ UTR regarding IRES activity2015
- Author(s)
  田中智久、森石恆司
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Strasbourg, France
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18779
[Presentation] Infection of equine hepacivirus in a closed colony of Japanese native hors（2015
- Author(s)
  Tomohisa Tanaka, Wenjia Chen, Teruhime Otoguro, Hirotake Kasai, Atsuya Yamashita, Kohji Moriishi
- Organizer
  22nd International meeting on hepatitis C virus and related viruses
- Place of Presentation
  Palais de la Musique et des Congres (フランス、ストラスブール)
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493
[Presentation] Metachromin A, sesquiterpene from marine sponge Dactylospongia metachromia, exerts anti-HBV activity via inhibition of HBV core promoter2015
- Author(s)
  Atsuya Yamashita, Tomohisa Tanaka, Kaori Okuyama-Dobashi, Hirotake Kasai, Koichi Watashi, Takaji Wakita,, Masaaki Toyama, Masanori Baba, Mayumi Tamaki, Junichi Tanaka, Kohji Moriishi
- Organizer
  日本ウイルス学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08493
[]

1. MORIISHI Kohji (90260273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. YAMASHITA Atsuya (00334871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. KASAI Hirotake (20324189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
4. 安達登 (60282125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 神澤秀明 (80734912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. ENOMOTO Nobuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. OKAMOTO Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 松浦善治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TANAKA Tomohisa 田中 智久

Tanaka Tomohisa 田中 智久

Research Projects

Research Products

Co-Researchers

ヘパシウイルス持続感染における自然免疫系の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新型コロナウイルスのnsp1依存性細胞傷害機構の解明とレプリコンモデルへの応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

History of humans and pathogens revealed by ancient viral genome analysis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the molecular mechanism of HBV entry and screening of HBV entry inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of genetic diversity and host-specificity of non-primate hepacivirusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of anti-hepatitis virus strategy based on proteomics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of the mechanism of SARS coronavirus nsp1-mediated mRNA decayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibitory effect of a novel thiazolidinedione derivative on hepatitis B virus entry2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of the 5' Untranslated Region of Nonprimate Hepacivirus in Translation Initiation and Viral Replication.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Seroepidemiology of non-primate hepacivirus (NPHV) in Japanese native horses2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Cinnamic acid derivatives inhibit hepatitis C virus replication via the induction of oxidative stress.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitory effect of presenilin inhibitor LY411575 on maturation of hepatitis C virus core protein, production of the viral particle and expression of host proteins involved in pathogenicity.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Inhibitory effect of CDK9 inhibitor FIT-039 on hepatitis B virus propagation2016

Author(s)

Journal Title

DOI

TANAKA Tomohisa 田中智久

Tanaka Tomohisa 田中智久