Unuma Kana 鵜沼香奈

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UNUMA Kana 鵜沼香奈

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Researcher Number	30586425
Other IDs
Affiliation (Current)	2023: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授(キャリアアップ)
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授(キャリアアップ) 2016 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2013 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 講師 2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 2010 – 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教 2008 – 2009: The University of Tokyo, 大学院・医学系研究科, 特別研究員(DC2)
Review Section/Research Field	Principal Investigator Legal medicine / Basic Section 58040:Forensics medicine-related Except Principal Investigator Legal medicine / Legal medicine / Basic Section 58080:Gerontological nursing and community health nursing-related / Medium-sized Section 58:Society medicine, nursing, and related fields
Keywords	Principal Investigator 敗血症 / 一酸化炭素 / 肝臓 / オートファジー / autophagy / リポポリサッカリド / プロテオーム / 法医学 / 心臓性突然死 / コネキシン … More / ギャップジャンクション / 情動ストレス / connexin43 / α-アドレナリン受容体 / 細胞間情報伝達 / ストレス / アドレナリン受容体 / miRNA / endotoxemia / heme oxygenase-1 / lipopolysaccharide / カルバモイルリン酸シンターゼ1 / CPS1 / 心臓 / ヘムオキシゲナーゼ / 酸化ストレス / LPS / hepatocyte / mitochondria / lysosomal exocytosis; / ミトコンドリア障害 / 活性酸素種 / ミトコンドリア / 硫化水素 / 敗血症性肝障害 / 急性肝障害 / ペルオキシレドキシン / Sepsis / Hepatocytes / Inflammation / GYY4137 / hepatocytes / inflammation / sepsis / コカイン / 心毒性 … More Except Principal Investigator sudden death / emotional stress / connexin43 / gap junction / arrhythmia / stress / gap junctions / 一酸化炭素 / CORM-3 / フィブロネクチン / p62 / 硫化水素 / メタボロミクス / プロテオミクス / ミトコンドリア / タンパク質凝集体 / ヘム / プロテオーム / 法医病理 / 高齢者虐待 / ピンク歯 Less

高齢者の身体的虐待の特徴と傾向に基づく関連機関の連携に関する研究
- Principal Investigator
  
  櫻田宏一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the cardiotoxic mechanism in rats after cocaine administration and the effect of carbon monoxidePrincipal Investigator
- Principal Investigator
  
  鵜沼香奈
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Tokyo Medical and Dental University
ピンク歯現象の発色および退色機序に関する検討
- Principal Investigator
  
  櫻田宏一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Tokyo Medical and Dental University
Molecular mechanism of H2S donor on liver damage in an animal model of sepsis.Principal Investigator
- Principal Investigator
  
  Unuma Kana
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of carbon monoxide toxicity using water-soluble CORMs
- Principal Investigator
  
  Aki Toshihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University
Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells.Principal Investigator
- Principal Investigator
  
  UNUMA Kana
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University
Cobalt protoporphyrin accelerates TFEB activation and lysosome reformation during LPS-induced septic insults in the rat heart.Principal Investigator
- Principal Investigator
  
  Unuma Kana
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University
Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liverPrincipal Investigator
- Principal Investigator
  
  UNUMA Kana
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University
Restraint stress induces connexin-43 translocation in rat heartPrincipal Investigator
- Principal Investigator
  
  UNUMA Kana
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University
拘束ストレスによるラット心筋コネクシン43(Connexin43)の動態。Research Fellow
- Research Fellow
  
  鵜沼香奈
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Legal medicine
- Research Institution
  The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] Autophagy in health and disease2018
- Author(s)
  Toshihiko Aki, Kanako Noritake, Kana Unuma, Koichi Uemura
- Total Pages
  18
- Publisher
  Humana press
- ISBN
  9783319981451
- Data Source
  KAKENHI-PROJECT-17H04147
[Book] Autophagy in Health and Disease2018
- Author(s)
  Aki T, Noritake K, Unuma K, Uemura K."
- Total Pages
  10
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-16K09203
[Book] 月刊「細胞」　THE CELL2016
- Author(s)
  鵜沼　香奈、秋　利彦
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-16K09203
[Journal Article] CT imaging of extraglottic airway device?pictorial review2021
- Author(s)
  Norii Tatsuya、Makino Yohsuke、Unuma Kana、Adolphi Natalie L.、Albright Danielle、Sklar David P.、Crandall Cameron、Braude Darren
- Journal Title
  
  Emergency Radiology
  
  Volume: 28(3) Pages: 665-673
- DOI
  10.1007/s10140-021-01909-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680
[Journal Article] Diagnosis by forensic autopsy of cannula malposition resulting in fatal tension pneumothorax after attempted percutaneous tracheostomy: A short communication2021
- Author(s)
  Wen Shuheng、Unuma Kana、Watanabe Ryo、Uemura Koichi
- Journal Title
  
  Journal of Forensic and Legal Medicine
  
  Volume: 81 Pages: 102177-102177
- DOI
  10.1016/j.jflm.2021.102177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680
[Journal Article] Inappropriate diet and fatal malnutrition in a 10-year-old child fed only infant formula throughout life: Novel pathological diagnostic criterion for starvation via lipophagy2021
- Author(s)
  Yamada Atsushi、Unuma Kana、Arai Nobutaka、Kitamura Osamu、Uemura Koichi
- Journal Title
  
  Forensic Science International
  
  Volume: 325 Pages: 110896-110896
- DOI
  10.1016/j.forsciint.2021.110896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680
[Journal Article] Altered cardiac mitochondrial dynamics and biogenesis in rat after short-term cocaine administration2021
- Author(s)
  Wen Shuheng、Unuma Kana、Funakoshi Takeshi、Aki Toshihiko、Uemura Koichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 24129-24129
- DOI
  10.1038/s41598-021-03631-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10680, KAKENHI-PROJECT-20H03955
[Journal Article] Fatal anaphylaxis due to alpha-gal syndrome after initial cetuximab administration: The first forensic case report2021
- Author(s)
  Wen Shuheng、Unuma Kana、Chinuki Yuko、Hikino Hajime、Uemura Koichi
- Journal Title
  
  Legal Medicine
  
  Volume: 51 Pages: 101878-101878
- DOI
  10.1016/j.legalmed.2021.101878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680
[Journal Article] Oxcarbazepine induces mitotic catastrophe and apoptosis in NRK-52E proximal tubular cells2021
- Author(s)
  Ota Momoka、Funakoshi Takeshi、Aki Toshihiko、Unuma Kana、Uemura Koichi
- Journal Title
  
  Toxicology Letters
  
  Volume: 350 Pages: 240-248
- DOI
  10.1016/j.toxlet.2021.07.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680, KAKENHI-PROJECT-19K10682
[Journal Article] Sustained splenic contraction after daily cocaine administration in rats2021
- Author(s)
  Nomura Moeka、Unuma Kana、Aki Toshihiko、Uemura Koichi
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 6 Pages: e0252853-e0252853
- DOI
  10.1371/journal.pone.0252853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680
[Journal Article] Fatal intracranial hemorrhage due to infantile acute lymphoblastic leukemia mimicking abusive head trauma2021
- Author(s)
  Unuma Kana、Makino Yohsuke、Yamamoto Kouhei、Hattori Shinya、Arai Nobutaka、Sakai Kentaro、Kitagawa Masanobu、Uemura Koichi、Kanegane Hirokazu
- Journal Title
  
  Journal of Forensic Sciences
  
  Volume: 66 Issue: 6 Pages: 2504-2510
- DOI
  10.1111/1556-4029.14815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680
[Journal Article] Presepsin: A potential superior diagnostic biomarker for the postmortem differentiation of sepsis based on the Sepsis-3 criteria2019
- Author(s)
  Unuma Kana、Makino Yohsuke、Sasaki Yoshiyuki、Iwase Hirotaro、Uemura Koichi
- Journal Title
  
  Forensic Science International
  
  Volume: 299 Pages: 17-20
- DOI
  10.1016/j.forsciint.2019.03.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09203
[Journal Article] Formation of high molecular weight p62 by CORM-32019
- Author(s)
  Aki Toshihiko、Unuma Kana、Noritake Kanako、Hirayama Naho、Funakoshi Takeshi、Uemura Koichi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 1 Pages: e0210474-e0210474
- DOI
  10.1371/journal.pone.0210474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
[Journal Article] Hydrogen sulfide donor NaHS causes bronchitis with enhanced respiratory secretion in rats2019
- Author(s)
  Unuma Kana、Aki Toshihiko、Yamashita Ayaka、Yoshikawa Ayaka、Uemura Koichi
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 44 Issue: 2 Pages: 107-112
- DOI
  10.2131/jts.44.107
- NAID
  130007590450
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203, KAKENHI-PROJECT-19K10680
[Journal Article] Increased circulating peroxiredoxin-4 in sepsis model rats involves secretion from hepatocytes and is mitigated by GYY41372019
- Author(s)
  Unuma Kana、Yoshikawa Ayaka、Aki Toshihiko、Uemura Koichi
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 32 Issue: 4 Pages: 305-310
- DOI
  10.1293/tox.2019-0030
- NAID
  130007731846
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10680, KAKENHI-PROJECT-18K19670, KAKENHI-PROJECT-17H04147
[Journal Article] The down-regulation of cardiac contractile proteins underlies myocardial depression during sepsis and is mitigated by carbon monoxide2018
- Author(s)
  Unuma Kana、Aki Toshihiko、Nagano Suguru、Watanabe Ryo、Uemura Koichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 2 Pages: 1668-1674
- DOI
  10.1016/j.bbrc.2017.12.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
[Journal Article] Necrosis in human neuronal cells exposed to paraquat2018
- Author(s)
  Naho Hirayama, Toshihiko Aki, Takeshi Funakoshi, Kanako Noritake, Kana Unuma, Koichi Uemura.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 43 Issue: 3 Pages: 193-202
- DOI
  10.2131/jts.43.193
- NAID
  130006507321
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
[Journal Article] Interaction of carbon monoxide-releasing ruthenium carbonyl CORM-3 with plasma fibronectin2018
- Author(s)
  Aki Toshihiko、Unuma Kana、Noritake Kanako、Kurahashi Hatsumi、Funakoshi Takeshi、Uemura Koichi
- Journal Title
  
  Toxicology in Vitro
  
  Volume: 50 Pages: 201-209
- DOI
  10.1016/j.tiv.2018.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
[Journal Article] Emerging roles of mitochondria and autophagy in liver injury during sepsis2017
- Author(s)
  Aki Toshihiko、Unuma Kana、Uemura Koichi
- Journal Title
  
  Cell Stress
  
  Volume: 1 Issue: 2 Pages: 79-89
- DOI
  10.15698/cst2017.11.110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09203, KAKENHI-PROJECT-17H04147
[Journal Article] A CO-releasing molecule prevents annexin A2 down-regulation and associated disorders in LPS-administered rat lung2017
- Author(s)
  Unuma Kana、Aki Toshihiko、Noritake Kanako、Funakoshi Takeshi、Uemura Koichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 487 Issue: 3 Pages: 748-754
- DOI
  10.1016/j.bbrc.2017.04.131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09203
[Journal Article] Restoration of YAP activation rescues HL-1 cardiomyocytes from apoptotic death by ethanol2017
- Author(s)
  Kanako Noritake, Toshihiko Aki, Moe Kimura, Takeshi Funakoshi, Kana Unuma, Koichi Uemura.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 42 Issue: 5 Pages: 545-551
- DOI
  10.2131/jts.42.545
- NAID
  130006076729
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15879, KAKENHI-PROJECT-17H04147
[Journal Article] Ataxia telangiectasia and rad3 related (ATR)-promyelocytic leukemia protein (PML) pathway of the DNA damage response in the brain of rats administered arsenic trioxide2017
- Author(s)
  Ryo Watanabe, Kana Unuma, Kanako Noritake, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura.
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 30 Issue: 4 Pages: 333-337
- DOI
  10.1293/tox.2017-0020
- NAID
  130006176567
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09201, KAKENHI-PROJECT-16K09203
[Journal Article] Necroptosis-like Neuronal Cell Death Caused by Cellular Cholesterol Accumulation.2016
- Author(s)
  Funakoshi T, Aki T, Tajiri M, Unuma K, Uemura K.
- Journal Title
  
  J Biol Chem
  
  Volume: 291(48) Pages: 25050-25065
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09203
[Journal Article] Hydrogen sulfide donor NaHS induces death of alveolar epithelial L2 cells that is associated with cellular shrinkage, transgelin expression and myosin phosphorylation2016
- Author(s)
  Fujii Y, Funakoshi T, Unuma K, Noritake K, Aki T, Uemura K.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 41 Issue: 5 Pages: 645-654
- DOI
  10.2131/jts.41.645
- NAID
  130005266228
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09203
[Journal Article] n Autopsy Case of Asphyxia Caused by Uncontrolled Hemorrhage Following Transbronchial Lung Biopsy.2016
- Author(s)
  3Watanabe M, Unuma K, Makino Y, Komatsu A, Yamada A, Nagai H, Uemura K.
- Journal Title
  
  J Clin Respir Dis Care
  
  Volume: 2 Issue: 3 Pages: 117-117
- DOI
  10.4172/2472-1247.1000117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09203
[Journal Article] Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse2016
- Author(s)
  Kimura-Kojima H, Unuma K, Funakoshi T, Kato C, Komatsu A, Aki T, Uemura K.
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 29 Issue: 2 Pages: 131-138
- DOI
  10.1293/tox.2015-0072
- NAID
  130005151012
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09203
[Journal Article] Lipopolysaccharide induces expression of collagen VI in the rat lung2015
- Author(s)
  Okawa S, Unuma K, Yamada A, Aki T, Uemura K
- Journal Title
  
  J Toxicol Pathol.
  
  Volume: 28(1) Issue: 1 Pages: 37-41
- DOI
  10.1293/tox.2014-0053
- NAID
  130004842606
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
[Journal Article] Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.2015
- Author(s)
  Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K.
- Journal Title
  
  PLoS One
  
  Volume: 10(8) Issue: 8 Pages: e0136952-e0136952
- DOI
  10.1371/journal.pone.0136952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06182, KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
[Journal Article] Lipopolysaccharide induces expression of collagen VI in the rat lung2015
- Author(s)
  Okawa S, Unuma K, Yamada A, Aki T, Uemura K.
- Journal Title
  
  J Toxicol Pathol.
  
  Volume: in press
- NAID
  130004842606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713024
[Journal Article] Immobilization Stress With <i>α</i><sub>2</sub>-Adrenergic Stimulation Induces Regional and Transient Reduction of Cardiac Contraction Through Gi Coupling in Rats2015
- Author(s)
  Kuroda R, Shintani-Ishida K, Unuma K, Yoshida KI.
- Journal Title
  
  Int. Heart J.
  
  Volume: 56 Issue: 5 Pages: 537-543
- DOI
  10.1536/ihj.15-034
- NAID
  130005102130
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26713024, KAKENHI-PROJECT-25293162
[Journal Article] Activation of Master Autophagy Regulator TFEB During Systemic LPS Administration in the Cornea2014
- Author(s)
  8.Kyoko Uchida, Kana Unuma, Takeshi Funakoshi, Toshihiko Aki, and Koichi Uemura
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 27 Issue: 2 Pages: 153-158
- DOI
  10.1293/tox.2014-0004
- NAID
  130003391349
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
[Journal Article] Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model2014
- Author(s)
  Sugihara M, Odagiri F, Suzuki T, Murayama T, Nakazato Y, Unuma K, Yoshida K, Daida H, Sakurai T, Morimoto S, Kurebayashi N.
- Journal Title
  
  PLoS One
  
  Volume: 8(1) Issue: 1 Pages: e55514-e55514
- DOI
  10.1371/journal.pone.0055514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249038, KAKENHI-PROJECT-23300145, KAKENHI-PROJECT-24590330, KAKENHI-PROJECT-24590331, KAKENHI-PROJECT-24790639, KAKENHI-PUBLICLY-25136718, KAKENHI-PUBLICLY-23136514
[Journal Article] Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis.2014
- Author(s)
  Mayumi Watanabe, Takeshi Funakoshi, Kana Unuma, Toshihiko Aki#, and Koichi Uemura
- Journal Title
  
  Toxicology
  
  Volume: 322 Pages: 43-50
- DOI
  10.1016/j.tox.2014.04.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-25460863, KAKENHI-PROJECT-26713024
[Journal Article] Immunohistochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic humanlivers2013
- Author(s)
  Kashima J, Shintani-Ishida K, Nakajima M, Maeda H, Unuma K, Uchiyama Y, Yoshida K
- Journal Title
  
  Hepatol Res
  
  Volume: 413 Issue: 7 Pages: 779-787
- DOI
  10.1111/hepr.12183
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249038, KAKENHI-PROJECT-24590851, KAKENHI-PROJECT-24659334, KAKENHI-PROJECT-24790639, KAKENHI-PROJECT-25293162, KAKENHI-PROJECT-26713024
[Journal Article] Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during LPS treatment inrat liver2013
- Author(s)
  Kana Unuma, Toshihiko Aki, Seiji Matsuda, Takeshi Funakoshi, Ken-ichi Yoshida, Koichi Uemura
- Journal Title
  
  Hepatology Res
  
  Volume: 43 Issue: 1 Pages: 91-96
- DOI
  10.1111/j.1872-034x.2012.01049.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590629, KAKENHI-PROJECT-22591637, KAKENHI-PROJECT-24790639
[Journal Article] Rho-Kinase Inhibitor Y-27632 Attenuates Arsenic Trioxide Toxicity in H9c2 Cardiomyoblastoma Cells.2013
- Author(s)
  Bessho M, Aki T, Funakoshi T, Unuma K, Noritake K, Kato C, Uemura K.
- Journal Title
  
  Cardiovasc Toxicol.
  
  Volume: 13(3) Issue: 3 Pages: 267-77
- DOI
  10.1007/s12012-013-9206-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790639
[Journal Article] Impairment of autophagy: From hereditary disorder to drug intoxication.2013
- Author(s)
  Aki T, Funakoshi T, Unuma K, Uemura K.
- Journal Title
  
  Toxicology.
  
  Volume: 311(3) Pages: 205-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790639
[Journal Article] Elimination and active extrusion of livermitochondrial proteins during LPS administration in rat2013
- Author(s)
  Kana Unuma, Toshihiko Aki, Seiji Matsuda, Takeshi Funakoshi, Ken-ichi Yoshida, Koichi Uemura
- Journal Title
  
  Hepatology Res
  
  Volume: 43 Issue: 5 Pages: 526-534
- DOI
  10.1111/j.1872-034x.2012.01084.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590629, KAKENHI-PROJECT-22591637, KAKENHI-PROJECT-24790639
[Journal Article] I n d u c e r o f h e me o x y g e n a s e - 1 c o b a l t p r o t o p o r p h y r i n a c c e l e r a t e s a u t o p h a g y a n d s u p p r e s s e s o x i d a t i v e d a ma g e s d u r i n g l i p o p o l y s a c c h a r i d e t r e a t me n t i n r a t l i v e r2013
- Author(s)
  Unuma K, A k i T, M a t s u d a S , F u n a k o s h i T, Yo s h i d a K , U e mu r a K
- Journal Title
  
  Hepatol Res
  
  Volume: 43(1) Pages: 91-6
- Data Source
  KAKENHI-PROJECT-24790639
[Journal Article] Lysosome vacuolation disrupts the completion of autophagy during norephedrine exposure in SH-SY5Y human neuroblastoma cells2013
- Author(s)
  Takeshi Funakoshi, Toshihiko Aki, Kana Unuma, Koichi Uemura
- Journal Title
  
  Brain Res
  
  Volume: 1490 Pages: 9-22
- DOI
  10.1016/j.brainres.2012.10.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590629, KAKENHI-PROJECT-24790639, KAKENHI-PROJECT-25860487
[Journal Article] Starch accumulation in the lungs of two infants following positive ventilation.2013
- Author(s)
  Unuma K, Harada K, Oka T, Uemura K.
- Journal Title
  
  Forensic Sci Med Pathol.
  
  Volume: 9(4) Issue: 4 Pages: 554-7
- DOI
  10.1007/s12024-013-9453-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790639
[Journal Article] Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes.2013
- Author(s)
  Funakoshi-Hirose I, Aki T, Unuma K, Funakoshi T, Noritake K, Uemura K.
- Journal Title
  
  Toxicology.
  
  Volume: 312(4) Pages: 74-82
- DOI
  10.1016/j.tox.2013.07.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790639, KAKENHI-PROJECT-25460862
[Journal Article] Connexin-43 redistribution and gap junction activation Buringforced restraint protects against sudden arrhythmic death in rats2010
- Author(s)
  Unuma K, Shintani-lshida K, Tsushima K, Shimosawa T, Ueyama T, Kuwahara M, Yoshida K.
- Journal Title
  
  Circ J.
  
  Volume: 74(6) Pages: 1087-1095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890049
[Journal Article] Connexin-43 redistribution and gap junction activation duringforced restraint protects against sudden arrhythmic death in rats2010
- Author(s)
  Unuma K, Shintani-Ishida K, Tsushima K, Shimosawa T, Ueyama T, Kuwahara M, Yoshida K
- Journal Title
  
  Circ J
  
  Volume: 74(6) Pages: 1087-1095
- Data Source
  KAKENHI-PROJECT-22890049
[Journal Article] Localization and mechanism of nephrocalcinosis in pseudo-Bartter's syndrome2010
- Author(s)
  Tojo A, Unuma K, Harada K, Yoshida K, Fujita T.
- Journal Title
  
  Kidney International 77(9)
  
  Pages: 831-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J08791
[Journal Article] Restraint stress induces connexin-43 translocation via a-adr enoceptors in rat heart2010
- Author(s)
  Unuma K, Shintani-lshida K, Yahagi N, Tsushima K, Shimosawa T, Ueyama T, Yoshida K.
- Journal Title
  
  Circ J.
  
  Volume: 74(12) Pages: 2693-2701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890049
[Journal Article] Connexin-43 redistribution and gap junction activation during forced restraint protects against arrhythmic death in rats2010
- Author(s)
  Unuma K, Shintani-Ishida K, Tsushima K, Shimosawa T, Ueyama T, Kuwahara M, Yoshida K.
- Journal Title
  
  Circ J (掲載確定(印刷中))
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J08791
[Journal Article] Restraint stress induces connexin-43 translocation viaα-adrenoceptors in ratheart2010
- Author(s)
  Unuma K, Shintani-Ishida K, Yahagi N, Tsushima K, Shimosawa T, Ueyama T, Yoshida K
- Journal Title
  
  Circ J
  
  Volume: 74(12) Pages: 2693-2701
- NAID
  10027424654
- Data Source
  KAKENHI-PROJECT-22890049
[Journal Article] Ischemia enhances translocation of connexin 43 and gap junction intercellular communication, thereby propagating contraction band necrosis after reperfusion2009
- Author(s)
  Shintani-Ishida K, Unuma K, Yoshida K.
- Journal Title
  
  Circ J 73
  
  Pages: 1661-1668
- NAID
  10025934936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J08791
[Journal Article] Autopsy report on pseudo-Bartter syndrome with renal calcification in duced by diuretics and diet pills. 2009,/bcr.12.2008.1380.2009
- Author(s)
  Unuma K, Tojo A, Harada K, Saka K, Nakajima M, Ishii T, Fujita T, Yoshida K.
- Journal Title
  
  BMJ Case Rep. doi:10((電子ジャーナル))
  
  Pages: 1136-1136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J08791
[Journal Article] An autopsy report on multiple system atrophy diagnosed immunohisto chemically despite severe ischaemic damage : a new approach for investigation of medical practice associated deaths in Japan2009
- Author(s)
  Nakajima M, Kojima H, Takazawa Y, Yahagi N, Harada K, Takahashi K, Unuma K, Yoshida K.
- Journal Title
  
  J Clin Pathol 62(11)
  
  Pages: 1029-1033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J08791
[Journal Article] Identification of active ingredients in dietary supplements using non-destructive massspectrometry and liquid chromatography-mass spectrometry2009
- Author(s)
  Saka K, Konuma K, Asai S, Unuma K, Nakajima M, Yoshida K.
- Journal Title
  
  Forensic Sci Int. 191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J08791
[Journal Article] An autopsy report on four sudden cardiac death cases by immobilization2008
- Author(s)
  Uemura K, Ueyama T, Shintani-Ishida K, Unuma K, Ken-ichi Y.
- Journal Title
  
  Inter. Med. J. 15(4)
  
  Pages: 301-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-08J08791
[Presentation] The Evaluation of the Routine Use of Postmortem Computed Tomography (PMCT) In a High-Volume United States Medical Examiner’s Office2021
- Author(s)
  Makino Y, Unuma K, Adolphi N, Nolte K.B.
- Organizer
  The Academy’s 73rdAnnual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10680
[Presentation] 敗血症性肝障害に対する硫化水素の影響2020
- Author(s)
  鵜沼香奈、秋利彦、吉川綾香、上村公一
- Organizer
  第103回法医学会全国集会
- Data Source
  KAKENHI-PROJECT-19K10680
[Presentation] 敗血症性肝障害に対する硫化水素の影響2019
- Author(s)
  鵜沼香奈、秋利彦、吉川綾香、上村公一
- Organizer
  第103回法医学会全国集会
- Data Source
  KAKENHI-PROJECT-19K10680
[Presentation] 敗血症性肝障害に対する硫化水素の影響2019
- Author(s)
  鵜沼香奈、秋利彦、吉川綾香、上村公一
- Organizer
  第103 次日本法医学会学術全国集会、仙台
- Data Source
  KAKENHI-PROJECT-17H04147
[Presentation] Down-regulation of cardiac contractile protein is involved in cardiac dysfunction during sepsis and is mitigated by carbon monoxide2018
- Author(s)
  Kana Unuma, Toshihiko Aki, Ryo Watanabe, Koichi Uemura
- Organizer
  The 24th Congress of the International Academy of Legal Medicine (IALM2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] Down-regulation of cardiac contractile protein is involved in cardiac dysfunction during sepsis and is mitigated by carbon monoxide.2018
- Author(s)
  Kana Unuma, Toshihiko Aki, Ryo Watanabe, Koichi Uemura
- Organizer
  IALM 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04147
[Presentation] 転倒による頭部打撲14時間後に急変した遅発性外傷性脳内出血の1剖検例2017
- Author(s)
  平山菜穂, 鵜沼香奈, 渡邊嶺, 上村公一
- Organizer
  第58回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] 乳幼児における薬物分析検査の重要性ー思いがけず薬物の寄与が明らかになった2剖検例2017
- Author(s)
  鵜沼香奈, 則竹香菜子, 船越丈司, 坂幹樹, 木村遥, 藤井祐介, 上村公一
- Organizer
  第101次日本法医学会全国集会
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] 交通事故後に見過ごされていた頭蓋外椎骨動脈の仮性動脈瘤破裂により死亡した一剖検例2017
- Author(s)
  渡邊嶺, 鵜沼香奈, 小松亜由美, 加世田莉奈, 永井みどり, 高橋蓮穂,古川真子, 上村公一
- Organizer
  第86回日本法医学会学術関東地方集会
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] 遊具の打撲に起因する延髄周囲の硬膜下血腫が見逃された例2017
- Author(s)
  平山菜穂, 鵜沼香奈, 槇野陽介, 渡邊嶺, 小松亜由美, 加世田莉奈, 佐野智美, 上村公一
- Organizer
  第101次日本法医学会全国集会
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] 覚せい剤原料ノルエフェドリン曝露による神経細胞内コレステロール異常蓄積とネクロトーシス誘導の解析2017
- Author(s)
  船越丈司, 秋利彦, 鵜沼香奈, 則竹香菜子, 上村公一
- Organizer
  第101 次日本法医学会全国集会
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] ノルエフェドリンによる神経細胞内コレステロール蓄積とネクロトーシス誘導の解析2017
- Author(s)
  船越丈司, 秋利彦, 鵜沼香奈, 則竹香菜子, 上村公一
- Organizer
  ConBio
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] CTにて明らかになった全身死蝋化を伴う頭部銃創の1例2016
- Author(s)
  鵜沼香奈,原田一樹,槇野陽介,小松亜由美,上村公一
- Organizer
  第100次日本法医学会学術全国集会
- Place of Presentation
  きゅりあん（東京都品川区）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] 遊具の打撲に起因する延髄周囲の硬膜下血腫が見逃された例遊具の打撲に起因する延髄周囲の硬膜下血腫が見逃された例2016
- Author(s)
  平山菜穂、鵜沼香奈、槇野陽介、渡邊　嶺、小松亜由美、上村公一
- Organizer
  第23回法医病理研究会
- Place of Presentation
  横浜市立大学医学部（神奈川県横浜市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] エンドトキシン刺激ラット肝細胞における障害ミトコンドリア処理機構の解析2016
- Author(s)
  鵜沼香奈
- Organizer
  第25回内毒素・LPS研究会
- Place of Presentation
  慶應義塾大学日吉キャンパス（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] 平滑筋細胞へのコカイン曝露による細胞毒性発現機構2016
- Author(s)
  木村遥,上村公一,秋利彦,鵜沼香奈,船越丈司
- Organizer
  第100次日本法医学会学術全国集会
- Place of Presentation
  きゅりあん（東京都品川区）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K09203
[Presentation] 敗血症性肺障害モデルにおけるコラーゲン分子の変動.2015
- Author(s)
  鵜沼香奈、大川紗由里、秋利彦、山田真嗣、上村公一.
- Organizer
  99次日本法医学会総会
- Place of Presentation
  高知市文化プラザ（高知県高知市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26713024
[Presentation] 覚せい剤原料ノルエフェドリン暴露による細胞内コレステロール蓄積とネクロトーシス誘導の解析2015
- Author(s)
  船越丈司、秋利彦、田尻正輝、鵜沼香奈、上村公一.
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26713024
[Presentation] Increase of MFG-E8 expression and its implications in vascular disorder by cocaine abuse.2015
- Author(s)
  木村　遥、鵜沼　香奈、秋　利彦、上村　公一.
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26713024
[Presentation] 敗血症モデルにおける各種臓器不全の分子学的検討2014
- Author(s)
  鵜沼　香奈
- Organizer
  第98次日本法医学会学術全国集会（学術奨励賞受賞講演）
- Place of Presentation
  福岡
- Year and Date
  2014-06-19
- Invited
- Data Source
  KAKENHI-PROJECT-26713024
[Presentation] ヘムオキシゲナーゼ誘導剤は敗血症ラットの心筋障害をオートファジー活性化を介して軽減する2013
- Author(s)
  鵜沼香奈、秋利彦、船越丈司、内田恭子、則竹香菜子、藤井祐介、上村公一
- Organizer
  97次日本法医学会総会
- Data Source
  KAKENHI-PROJECT-24790639
[Presentation] ヘムオキシゲナーゼ誘導剤は敗血症ラットの心筋障害をオートファジー活性化を介して軽減する2013
- Author(s)
  鵜沼香奈、秋利彦、船越丈司、内田恭子、則竹香菜子、藤井祐介、上村公一
- Organizer
  第97次日本法医学会学術全国集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24790639
[Presentation] プロテオーム及びin vivo系を用いた敗血症における新たなバイオマーカーの同定2012
- Author(s)
  鵜沼香奈,秋利彦,則竹香菜子,上村公一
- Organizer
  96次日本法医学会総会
- Data Source
  KAKENHI-PROJECT-24790639
[Presentation] プロテオーム及びin vivo系を用いた敗血症における新たなマーカーの同定2012
- Author(s)
  鵜沼香奈、秋利彦、則竹香菜子、上村公一
- Organizer
  96次日本法医学会総会
- Place of Presentation
  アクトシティ浜松
- Data Source
  KAKENHI-PROJECT-24790639
[Presentation] 硫化水素による心筋細胞障害の検討2010
- Author(s)
  白鳥典、船越丈司、鵜沼香奈、秋利彦、上村公一
- Organizer
  日本法医学会学術学会関東地方会
- Place of Presentation
  笹川記念会館東京
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22890049
[Presentation] 長期生存した Williams 症候群患者の一剖検例2009
- Author(s)
  鵜沼香奈、原田一樹、中嶋信、小林貴、永井恒志、黒田亮平、吉田謙一
- Organizer
  第78回日本法医学会学術関東地方会
- Place of Presentation
  東京歯科大学(東京都)
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-08J08791
[Presentation] ダイエット薬乱用による偽性バーター症候群の剖検例における結石形成機序の考察2009
- Author(s)
  鵜沼香奈、藤乗嗣泰、原田一樹、中嶋信、藤田敏郎、吉田謙一
- Organizer
  第41回臨床体液学会
- Place of Presentation
  東京逓信病院(東京都)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-08J08791
[Presentation] Effect of gap junction inhibitor on heart, in psychological stress-induced cardiac response in rat2008
- Author(s)
  Unuma K, Shintani-Ishida K, Tsushima K, Shimosawa T, Yoshida K
- Organizer
  7^<th> International Symposium Advances In Legal Medicine
- Place of Presentation
  Osaka, central public hall
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-08J08791
[Presentation] Activation of ubiquitin-proteasome system plays a protective role in arsenic trioxide-induced cardiotoxicity.
- Author(s)
  Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K.
- Organizer
  9th International Symposium on Advances in Legal Medicine
- Place of Presentation
  Fukuoka
- Year and Date
  2014-06-16 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-26713024
[Presentation] Secretion of mitochondrial contents through autophagolysosomal exocytosis from lipopolysaccharide-stimulated hepatocytes and embryonic fibroblasts
- Author(s)
  Kana Unuma, Toshihiko Aki, Takeshi Funakoshi, Koichi Uemura
- Organizer
  9th International Symposium on Advances in Legal Medicine
- Place of Presentation
  Fukuoka
- Year and Date
  2014-06-16 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-26713024
[Presentation] マウス心房由来HL-1 細胞の亜砒酸誘導性アポトーシスにおけるユビキチン―プロテアソーム系の抑制作用.
- Author(s)
  渡邉　まゆ美, 船越　丈司, 鵜沼　香奈, 秋　利彦, 上村　公一.
- Organizer
  第87 回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26713024

1. 櫻田宏一 (10334228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 峰岸沙希 (00882820)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 上村公一 (30244586)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. Aki Toshihiko (60304474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. 船越丈司 (40444715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 則竹香菜子 (40758067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 戸谷麻衣子 (10900045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 池谷博 (30292874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 井上郁 (60628642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MORIMOTO Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 吉田謙一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 国広なごみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Unuma Kana 鵜沼 香奈

UNUMA Kana 鵜沼 香奈

Research Projects

Research Products

Co-Researchers

高齢者の身体的虐待の特徴と傾向に基づく関連機関の連携に関する研究

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Elucidation of the cardiotoxic mechanism in rats after cocaine administration and the effect of carbon monoxidePrincipal Investigator

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ピンク歯現象の発色および退色機序に関する検討

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Molecular mechanism of H2S donor on liver damage in an animal model of sepsis.Principal Investigator

Principal Investigator

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Analysis of carbon monoxide toxicity using water-soluble CORMs

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Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells.Principal Investigator

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Cobalt protoporphyrin accelerates TFEB activation and lysosome reformation during LPS-induced septic insults in the rat heart.Principal Investigator

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Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liverPrincipal Investigator

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Restraint stress induces connexin-43 translocation in rat heartPrincipal Investigator

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拘束ストレスによるラット心筋コネクシン43(Connexin43)の動態。Research Fellow

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Research Institution

[Book] Autophagy in health and disease2018

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[Book] Autophagy in Health and Disease2018

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[Book] 月刊「細胞」 THE CELL2016

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Unuma Kana 鵜沼香奈

UNUMA Kana 鵜沼香奈

[Book] 月刊「細胞」　THE CELL2016