TAKASHIMA Yukiko 高島由紀子

Researcher Number	30589768
Affiliation (based on the past Project Information) *help	2019: 岡山大学, 歯学部, 博士研究員 2018: 岡山大学, 大学病院, 講師 2016 – 2017: 岡山大学, 医歯薬学総合研究科, 助教 2013 – 2015: 岡山大学, 医歯(薬)学総合研究科, 助教
Review Section/Research Field	Principal Investigator Orthodontics/Pediatric dentistry Except Principal Investigator Orthodontics/Pediatric dentistry
Keywords	Principal Investigator バイオインフォマティクス / 齲蝕 / グルカン結合タンパク / Streptococcus mutans / Gbp / 結合ドメイン / バイオフィルム / gbpC 遺伝子 / う蝕 / GbpC … More / グルカン結合タンパクC / Gbpc / 唾液タンパク / バイオインフォマティックス / デキストラン結合能 … More Except Principal Investigator 歯周病 / 齲蝕 / 口腔内細菌 / 小児 / 乳酸桿菌 / Streptococcus mutans / 悪性腫瘍 / 口腔レンサ球菌 / 周術期 / ミュ-タンスレンサ球菌 / 歯周病菌 / 造血幹細胞移植 / 周術期歯科治療 / ミュ-タンス連鎖球菌 / 歯周病細菌 / 幹細胞移植 / 小児がん / プロテオーム / 微生物 / トランスポーター / Porphyromonas gingivalis / シグナル伝達システム / 膜トランスポーター / バイオフィルム / ABCトランスポーター / リスク特定 / 日本 / リスク / リスク判定 / ミュータンス菌 / 歯科健診 / う蝕 / 保育園 / 幼稚園 / タイ / 分子疫学的手法 Less

Dental caries prevention methods using GbpC glucan-binding domain in S. mutans.Principal Investigator
- Principal Investigator
  
  TAKASHIMA YUKIKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Okayama University
ABC transporter function in biofilm formation and its application for dental caries prevention
- Principal Investigator
  
  NAKANO Michiyo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Okayama University
Development of novel caries suppression method targeting polymer binding domain of plaque constituting bacteriaPrincipal Investigator
- Principal Investigator
  
  Takashima Yukiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Okayama University
Construction of global standard molecular epidemiological method for identification of the children at risk for severe dental caries
- Principal Investigator
  
  Nakano Kazuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Osaka University
Clinical effects of hematopoietic stem cell transplantation on oral microflora using microbiological analysis
- Principal Investigator
  
  Hirano keiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Okayama University
Establishment of method for search of functional domain in Streptococcus mutansPrincipal Investigator
- Principal Investigator
  
  TAKASHIMA Yukiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Okayama University

All 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Cariogenic properties of Streptococcus mutans clinical isolates with sortase defects.2017
- Author(s)
  Lapirattanakul J, Takashima Y, Tantivitayakul P, Maudcheingka T, Leelataweewud P, Nakano K, Matsumoto-Nakano M.
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 81 Pages: 7-14
- DOI
  10.1016/j.archoralbio.2017.04.018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05300, KAKENHI-PROJECT-16H05550
[Journal Article] Contributions of Streptococcus mutans Cnm and PA antigens to aggravation of non-alcoholic steatohepatitis in mice2016
- Author(s)
  Naka S, Hatakeyama R, Takashima Y, Matsumoto-Nakano M, Nomura R, Nakano K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 36886-36886
- DOI
  10.1038/srep36886
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20586, KAKENHI-PROJECT-15K20591
[Journal Article] Characterization of the dextran-binding domain in the glucan-binding protein C of Streptococcus mutans.2015
- Author(s)
  Takashima Y, Fujita K, Ardin AC, Nagayama K, Nomura R, Nakano K, Matsumoto-Nakano M.
- Journal Title
  
  Journal of Applied Microbiology
  
  Volume: 119 Issue: 4 Pages: 1148-1157
- DOI
  10.1111/jam.12895
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20591
[Journal Article] Role of ABC transpoter proteins in stress responses of Streptococcus mutans.2014
- Author(s)
  Nagayama K, Fujita K, Takashima Y, Ardin AC, Ooshima T, Matsumoto-Nakano M.
- Journal Title
  
  Oral Health Dent Manag.
  
  Volume: 13 Pages: 359-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25862013
[Journal Article] Contribution of glucan-binding protein A to firm and stable biofilm formation by Streptococcus mutans.2014
- Author(s)
  Matsumi Y, Fujita K, Takashima Y, Yanagida K, Morikawa Y, Matsumoto-Nakano M.
- Journal Title
  
  Mol Oral Microbiol.
  
  Volume: - Issue: 3 Pages: 1-10
- DOI
  10.1111/omi.12085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24593089, KAKENHI-PROJECT-25670874, KAKENHI-PROJECT-25862013
[Presentation] Streptococcus mutans の Gbps 結合ドメインに対する抗体の齲蝕への影響2019
- Author(s)
  高島由紀子、浅海春華、後藤花奈、森川優子、仲周平、仲野道代
- Organizer
  第３８回日本小児歯科学会中四国地方会大会および総会
- Data Source
  KAKENHI-PROJECT-17K11961
[Presentation] Role of molecular chaperon DnaK in Streptococcus mutans biofilm formation2018
- Author(s)
  Matsumoto-Nakano M, Yoshida E, Matsumi Y, Takashima Y
- Organizer
  第96回国際歯科研究学会（IADR）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] 乳酸菌由来のバクテリオシンがStreptococcus mutansのバイオフィルム形成に与える影響2018
- Author(s)
  森本節代, 森川優子, 高島由紀子, 仲周平, 稲葉裕明, 仲野道代
- Organizer
  第56回日本小児歯科学会
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] Streptococcus mutansのバイオフィルム形成におけるDnaKの影響と役割2018
- Author(s)
  吉田衣里, 松三友紀, 森川優子, 仲　周平, 高島由紀子, 仲野道代
- Organizer
  第56回日本小児歯科学会
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] 造血幹細胞移植患者の口腔内より分離した細菌叢の継時的変化2017
- Author(s)
  高島由紀子、吉田衣里、平野慶子、角田陽子、仲野道代
- Organizer
  第55回日本小児歯科学会大会
- Data Source
  KAKENHI-PROJECT-15K11366
[Presentation] 乳酸菌が産生するバクテリオシンが口腔バイフォイルム形成に与える影響2017
- Author(s)
  森本節代、森川優子、高島由紀子、仲周平、稲葉裕明、仲野道代
- Organizer
  第36回日本小児歯科学会中四国地方会大会および総会
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] Expression of molecular chaperon DnaK on biological functions in Streptococcus mutans2017
- Author(s)
  E. Yoshida, Y. Matsumi, Y. Takashima, and M. Matsumoto-Nakano
- Organizer
  95th General Session & Exhibition of the IADR
- Place of Presentation
  San Francisco, USA
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] Streptococcus mutansにおける分子シャペロンDnaKの役割2017
- Author(s)
  吉田衣里、松三友紀、高島由紀子、仲野道代
- Organizer
  第55回日本小児歯科学会大会
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] 小児口腔より分離されたラクトバシラスがStreptococcus mutansのバイフォフィルム形成に与える影響2017
- Author(s)
  森本節代、高島由紀子、仲野道代
- Organizer
  第55回日本小児歯科学会大会
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] 小児がん患者の口腔内細菌叢に対する造血幹細胞移植の影響について2017
- Author(s)
  平野慶子、吉田衣里、森川優子、高島由紀子、仲野道代
- Organizer
  第64回日本小児保健協会学術集会
- Data Source
  KAKENHI-PROJECT-15K11366
[Presentation] Streptococcus mutansにおける分子シャペロンDnaKの役割2017
- Author(s)
  吉田衣里、松三友紀、高島由紀子、仲野道代
- Organizer
  第５５回日本小児歯科学会大会
- Data Source
  KAKENHI-PROJECT-17K11961
[Presentation] Interactions between Lactobacillus strains and Streptococcus mutans for biofilm formation2017
- Author(s)
  S. Morimoto, Y. Takashima, and M. Matsumoto-Nakano
- Organizer
  95th General Session & Exhibition of the IADR
- Place of Presentation
  San Francisco, USA
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] Glucan-binding domain in GbpC of Streptococcus mutans contributes to binding to type I collagen2016
- Author(s)
  Yukiko Takashima, Yuko Morikawa, Kazuyo Fujita, and Michiyo Matsumoto-Nakano
- Organizer
  94th General Session & Exihibition of the IADR
- Place of Presentation
  Seoul, Republic of Korea
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20591
[Presentation] Perioperative Oral Bacterial Population in Patients Undergoing Hematopoietic Cell Transplantation2016
- Author(s)
  Keiko Hirano, Youko Tsunoda, Yukiko Takashima, Michiyo Nakano
- Organizer
  2016 IADR General Session
- Place of Presentation
  ソウル
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11366
[Presentation] Perioperative oral bacterial population in patients undergoing hematopoietic cell2016
- Author(s)
  Keiko Hirano, Yoko Tsunoda, Yukiko Takashima, Michiyo Matsumoto-Nakano
- Organizer
  16th International Asossiate foe Dental Research general session
- Place of Presentation
  Seoul（Korea)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11366
[Presentation] Functional analysis of role of glutamine metabolism-related gene in biofilm formation by Streptococcus mutans2016
- Author(s)
  Yuko Morikawa, Yukiko Takashima, Kazuyo Fujita, Michiyo Matsumoto-Nakano
- Organizer
  10th Biennial Conference of the Pediatric Dentistry Association of Asia
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] Effects of molecular chaperon DnaK on Biolfilm formation by Streptococcus mutans2016
- Author(s)
  E. Yoshida, Y. Matsumi, Y. Takashima, and M. Matsumoto-Nakano
- Organizer
  10th Biennial Conference of the Pediatric Dentistry Association of Asia
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05550
[Presentation] 本院小児医療センター開設後の当科における患者実態調査2016
- Author(s)
  高島由紀子、吉田翔、森本節代、吉田衣里、角田陽子、平野慶子、稲葉裕明、仲野道代
- Organizer
  第35回日本小児歯科学会中四国地方会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-15K20591
[Presentation] 造血幹細胞移植患者における口腔内細菌叢の変化2016
- Author(s)
  吉田衣里、森川優子、高島由紀子、森本節代、平野慶子、仲野道代
- Organizer
  第63回日本小児保健学術集会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-15K11366
[Presentation] Role of glucan-binding domain of GbpC in biofilm formation by Streptococcus mutans.2015
- Author(s)
  Yukiko Takashima, Yuko Morikawa, Kazuyo Fujita, Michiyo Matsumoto-Nakano
- Organizer
  The 25th Congress of the International Association of Paediatric Dentistry
- Place of Presentation
  The Scottish Exhibition & Conference Centre (SECC)
- Year and Date
  2015-07-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20591
[Presentation] Streptococcus mutans のバイオフィルム形成におけるグルカン結合領域の役割2015
- Author(s)
  高島由紀子, 森川優子, 藤田一世, 仲野道代
- Organizer
  第53回日本小児歯科学会大会
- Place of Presentation
  広島国際会議場
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K20591
[Presentation] Binding mechanism of Streptococcus mutans glucan-binding domain of GbpC to saliva proteins.2015
- Author(s)
  Yukiko Takashima, Yuko Morikawa, Kazuyo Fujita, Michiyo Matsumoto-Nakano
- Organizer
  The 63rd Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20591
[Presentation] Identification of Functional Biological Domains of GbpC in Streptococcus mutans.2013
- Author(s)
  Y.Takashima, K. Fujita, A. C. Ardin, and M. Matsumoto-Nakano
- Organizer
  2nd Meeting of the International Association for Dental Research Asia Pacific Region
- Place of Presentation
  Plaza Athenee, Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-25862013
[Presentation] Streptococcus mutans のグルカン結合タンパク C の構造による性状の比較2013
- Author(s)
  高島由紀子、藤田一世、仲野道代
- Organizer
  第５１回　日本小児歯科学会大会
- Place of Presentation
  長良川国際会議場
- Data Source
  KAKENHI-PROJECT-25862013
[Presentation] Function of dextran-binding domain encoding peptide in Streptococcus mutans
- Author(s)
  Takashima Y, Fujita K, Matsumoto-Nakano M.
- Organizer
  92th International Association for Dental Research General Session and Exhibition
- Place of Presentation
  Cape Town, South Africa
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PROJECT-25862013
[Presentation] Streptococcus mutansのバイオフィルム形成におけるグルカン結合領域の役割
- Author(s)
  高島由紀子、森川優子、藤田一世、仲野道代
- Organizer
  第５３回日本小児歯科学会大会
- Place of Presentation
  広島
- Year and Date
  2015-05-21 – 2015-05-22
- Data Source
  KAKENHI-PROJECT-25862013

1. NAKANO Michiyo (30359848)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
2. Hirano keiko (50335618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 藤田一世 (00437386)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. Nakano Kazuhiko (00379083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 仲周平 (10589774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 大川玲奈 (80437384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 野村良太 (90437385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 稲葉裕明 (70359850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. LAPIRATTANAKUL Jinthana

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

TAKASHIMA Yukiko 高島 由紀子

Research Projects

Research Products

Co-Researchers

Dental caries prevention methods using GbpC glucan-binding domain in S. mutans.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ABC transporter function in biofilm formation and its application for dental caries prevention

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel caries suppression method targeting polymer binding domain of plaque constituting bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of global standard molecular epidemiological method for identification of the children at risk for severe dental caries

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical effects of hematopoietic stem cell transplantation on oral microflora using microbiological analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of method for search of functional domain in Streptococcus mutansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cariogenic properties of Streptococcus mutans clinical isolates with sortase defects.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Contributions of Streptococcus mutans Cnm and PA antigens to aggravation of non-alcoholic steatohepatitis in mice2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of the dextran-binding domain in the glucan-binding protein C of Streptococcus mutans.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of ABC transpoter proteins in stress responses of Streptococcus mutans.2014

Author(s)

Journal Title

Data Source

[Journal Article] Contribution of glucan-binding protein A to firm and stable biofilm formation by Streptococcus mutans.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Streptococcus mutans の Gbps 結合ドメインに対する抗体の齲蝕への影響2019

Author(s)

Organizer

Data Source

[Presentation] Role of molecular chaperon DnaK in Streptococcus mutans biofilm formation2018

Author(s)

Organizer

Data Source

[Presentation] 乳酸菌由来のバクテリオシンがStreptococcus mutansのバイオフィルム形成に与える影響2018

Author(s)

Organizer

Data Source

[Presentation] Streptococcus mutansのバイオフィルム形成におけるDnaKの影響と役割2018

Author(s)

Organizer

Data Source

TAKASHIMA Yukiko 高島由紀子