Kuwahara Yasumichi 桑原康通

… Alternative Names

KUWAHARA YASUMICHI 桑原康通

KUWAHARA Yasumichi 〓原康通

桑原康通クワハラヤスミチ

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Researcher Number	30590327
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2025: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2022 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2015 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2013 – 2014: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2011: 京都府立医科大学, 医学研究科, 助教 2010 – 2011: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator ラブドイド腫瘍 / SWI/SNF複合体 / RUNX1 / SNF5 / 悪性ラブドイド腫瘍 / Mcl-1 / NOXA / 治療抵抗性 / TRKA / スーパーエンハンサー … More / SWI/SNF / RUNX / クロマチンリモデリング因子 / 転写制御 / Rhabdoid腫瘍 / クロマチン免疫沈降法 / 薬剤耐性 / アポトーシス / 薬剤感受性 / クロマチンリモデリング / p53 / p21 / hSNF5 … More Except Principal Investigator 翻訳後修飾 / 転写因子 / 造血発生 / 白血病 / Yeast Two-Hybrid / RUNX1 / 染色体転座 / クロマチンリモデリング / キナーゼ / リン酸化 / 造血幹細胞 / Yeast two-hybrid / Yeast two hybrid / C11orf21 / TRAIL / 転写調節 / 遺伝子改変マウス / 分子標的薬 / AML1 / 転写制御 / 造血器腫瘍 / INI1 / 新規治療 / SMARCB1 / 癌幹細胞 / がん幹細胞 / CD44 / survivin / FOXM1 / 幹細胞 / ラブドイド腫瘍 / 融合遺伝子 / PD-1 / PD-L1 / 免疫チェックポイント / 横紋筋肉腫 / 免疫療法 / 小児がん / 再発 / ｽｰﾊﾟｰﾊｲﾘｽｸ / ハイリスク / スーパーハイリスク / 神経芽腫 Less

Molecular Dissection of Acquired Therapy Resistance in Rhabdoid Tumors and the Development of Targeted Therapeutic InterventionsPrincipal Investigator
- Principal Investigator
  
  桑原康通
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Functional analysis of transcription factors and novel SWI/SNF complexes in the tumorigenesis of rhabdoid tumors.Principal Investigator
- Principal Investigator
  
  桑原康通
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the molecular mechanisms of malignant rhabdoid tumors mediated by dysregulation of super-enhancer function.Principal Investigator
- Principal Investigator
  
  Kuwahara Yasumichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Search for novel intervention methods for hematopoietic transcription control and research for its clinical application
- Principal Investigator
  
  Okuda Tsukasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Identifying and analyzing biological characteristics of rhabdoid tumor stem cells to establish new treatment
- Principal Investigator
  
  Katsumi Yoshiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
The clarification of a tumorigenesis of malignant rhabdoid tumor through a understanding of control mechanism of RUNX1 by hSNF5Principal Investigator
- Principal Investigator
  
  Kuwahara Yasumichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Study of recurrence mechanism in super high-risk neuroblastoma
- Principal Investigator
  
  Tomoko Iehara
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
The establishment of peptide vaccine as a consolidation therapy for childhood cancer.
- Principal Investigator
  
  Hosoi Hajime
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
The Epigenome Analysis of the Mechanisms of Chemoresistance and Development new treatment in Rhabdoid TumorPrincipal Investigator
- Principal Investigator
  
  KUWAHARA YASUMICHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
The determination of the hSNF5 target genes and the clarification of the transcriptional mechanism of hSNF5Principal Investigator
- Principal Investigator
  
  KUWAHARA Yasumichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors2023
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 15 Pages: 16323-16336
- DOI
  10.1002/cam4.6255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07941, KAKENHI-PROJECT-22K08483
[Journal Article] C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO2022
- Author(s)
  Matsumoto Akifumi、Yoshida Tatsushi、Shima Takahiro、Yamasaki Kenta、Tadagaki Kenjiro、Kondo Noriko、Kuwahara Yasumichi、Zhang Dong-Er、Okuda Tsukasa
- Journal Title
  
  BBA Advances
  
  Volume: 2 Pages: 100047-100047
- DOI
  10.1016/j.bbadva.2022.100047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846
[Journal Article] Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors2022
- Author(s)
  Shinohara Haruka、Sawado Rie、Nakagawa Makoto、Hattori Ayuna、Yamagata Kazutsune、Tauchi Kimiharu、Ito Jumpei、Kuwahara Yasumichi、Okuda Tsukasa、Ogawa Chitose、Kitabayashi Issay
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 27 Pages: 14-25
- DOI
  10.1016/j.omto.2022.09.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08483
[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand is a novel transcriptional target of runt-related transcription factor 12022
- Author(s)
  Yoshida Tatsushi、Yamasaki Kenta、Tadagaki Kenjiro、Kuwahara Yasumichi、Matsumoto Akifumi、Sofovic Adem、Kondo Noriko、Sakai Toshiyuki、Okuda Tsukasa
- Journal Title
  
  International Journal of Oncology
  
  Volume: 60 Issue: 1 Pages: 1-1
- DOI
  10.3892/ijo.2021.5296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] Novel Two MRT Cell Lines Established from Multiple Sites of a Synchronous MRT Patient2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara, Eisuke Ichise, Yoshiki Katsumi, Kazutaka Ouchi, Kunihiko Tsuchiya, Mitsuru Miyachi, Eiichi Konishi, Hiroyasu Sasajima, Satoaki Nakamura, Shigehisa Fumino, Tatsuro Tajiri, Pascal D Johann, Michael Fruhwald, Tsukasa Okuda, Hajime Hosoi
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 11 Pages: 6159-6170
- DOI
  10.21873/anticanres.14636
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08257, KAKENHI-PROJECT-19K08846, KAKENHI-PROJECT-19K09053, KAKENHI-PROJECT-19H03719
[Journal Article] A NOXA/MCL-1 Imbalance Underlies Chemoresistance of Malignant Rhabdoid Tumor Cells.2015
- Author(s)
  Ouchi K, Kuwahara Y, Iehara T, Miyachi M, Katsumi Y, Tsuchiya K, Konishi E, Yanagisawa A, Hosoi H.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 9999 Issue: 9 Pages: 1-9
- DOI
  10.1002/jcp.25293
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461602
[Journal Article] SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.2014
- Author(s)
  Wei D, Goldfarb D, Song S, Cannon C, Yan F, Sakellariou-Thompson D, Emanuele M, Major MB, Weissman BE, Kuwahara Y.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 12 Issue: 11 Pages: 1574-1585
- DOI
  10.1158/1541-7786.mcr-14-0005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461602
[Journal Article] SNF5 reexpression in malignant rhabdoid tumors regulates transcription of target genes by recruitment of　SWI/SNF complexes and RNAPII to the transcription start site of their promoters．2013
- Author(s)
  Kuwahara Y, Wei D, Durand J, Weissman BE．
- Journal Title
  
  Mol Cancer Res
  
  Volume: 11 Issue: 3 Pages: 251-260
- DOI
  10.1158/1541-7786.mcr-12-0390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461602
[Journal Article] Sensitivity of malignant rhabdoid tumor cell lines to PD0332991 is inverserly correlated with p16 expression2011
- Author(s)
  Katsumi Y, Iehara T, Miyachi M, Yagyu Y, Tsubai-Shimizu T, Kikuchi K, Tamura S, Itoh H, Kuwahara Y, Tsuchiya K, Kuroda H, Sugimoto T, Houghton PJ, Hosoi H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413 Pages: 62-68
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Role of the RUNX family in the NRTK1 gene regulation for neuroblastoma cells.2022
- Author(s)
  Aya Nakae, Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会
- Data Source
  KAKENHI-PROJECT-22K07941
[Presentation] Role of the RUNX family in the NRTK1 gene regulation for neuroblastoma cells.2022
- Author(s)
  Aya Nakae, Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会大会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] TRAIL is a novel target gene of RUNX1/AML1 transcription factor.2022
- Author(s)
  Tatsushi YOSHIDA, Kenta YAMASAKI, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Akifumi MATSUMOTO, Adem Ejub SOFOVIC, Noriko KONDO, Toshiyuki SAKAI, Tsukasa OKUDA
- Organizer
  第84回日本血液学会学術集会　（博多）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] Transcriptional regulation of G1-cyclin gene CCND1 by RUNX1 and its leukemia-related form RUNX1-ETO.2022
- Author(s)
  Yoshihito Shimizu, Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第45回日本分子生物学会年会（幕張）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] RUNX1 requires SNF5 for its functional cooperation with the chromatin remodeling complex, SWI/SNF.2022
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会大会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] A seaweed-derived compound that inhibits growth of acute myeloid leukemia cells.2021
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Yasumichi Kuwahara, Tsukasa Okuda.
- Organizer
  第80回日本癌学会学術総会（横浜）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Two New MRT Cell Lines Established from Multiple Sites of a Synchronous MRT with a Unique DNA Methylation Pattern.2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara,Yoshiki Katsumi, Kunihiko Tsuchiya　,Mitsuru Miyachi, Tatsuro Tajiri, Tatsushi Yoshida, Tsukasa Okuda, Hajime Hosoi
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08257
[Presentation] Two New MRT Cell Lines Established from Multiple Sites of a Synchronous MRT with a Unique DNA Methylation Pattern.2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara,Yoshiki Katsumi, Kunihiko Tsuchiya　,Mitsuru Miyachi, Tatsuro Tajiri, Tatsushi Yoshida, Tsukasa Okuda, Hajime Hosoi
- Organizer
  第79回日本癌学会学術総会（広島）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Identification of a novel RUNX1 target by public data re-analysis that is suppressed by RUNX1-ETO2019
- Author(s)
  Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Donger Zhang, Tsukasa Okuda
- Organizer
  第81回日本血液学会学術集会（東京）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Analysis of a novel transcriptional target gene of RUNX1.2019
- Author(s)
  Tatsushi YOSHIDA, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Toshiyuki SAKAI, and Tsukasa OKUDA
- Organizer
  第78回　日本癌学会学術総会（京都）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] 造血関連転写因子 RUNX1による制御遺伝子の探索2019
- Author(s)
  山崎健太、忠垣憲次郎、近藤則子、桑原康通、吉田達士、奥田司
- Organizer
  第42回日本分子生物学会年会（福岡）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Newly established MRT cell lines from multiple sites of a synchronous MRT patient2018
- Author(s)
  Yasumichi Kuwahara, Hajime Hosoi, Tsukasa Okuda
- Organizer
  International Rhabdoid Tumor Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] Functional interaction between SWI/SNF complex and a hematopoietic transcription factor in malignant rhabdoid tumor.2018
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenjiro Tadagaki　and Tsukasa Okuda
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] Mechanism of recruitment of SWI/SNF complex via interaction between SNF5 and transcription factor.2017
- Author(s)
  Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda
- Organizer
  2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会/第90回日本生化学会大会)
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] Loss of NOXA expression by INI1/SNF5 loss impaired sensitivity to chemotherapeutic agents in malignant rhabdoid tumor in vitro and iv vivo.2015
- Author(s)
  Ouchi K, Kuwahara Y, Iehara T, Konishi E, Hosoi H.
- Organizer
  106th American Association for Cancer Research Annual Meeting．
- Place of Presentation
  Philadelphia, PA，U.S.A．
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461602
[Presentation] Malignant Rhabdoid Tumor(悪性ラブドイド腫瘍: MRT)の最新治療と今後の課題:COG、EUの現況をふまえて2012
- Author(s)
  〓原康通, 勝見良樹、土屋邦彦、家原知子、細井創
- Organizer
  平成23年度日本ウィルムス腫瘍スタディ(JWiTS)研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株におけるhSNF5によるp53標的遺伝子の発現制御2011
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  平成22年度日本ウィルムス腫瘍スタディ(JWiTS)研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株におけるhSNF5によるp53標的遺伝子の発現制御2011
- Author(s)
  桑原康通、B Weissman、細井創
- Organizer
  日本Wilms腫瘍研究会
- Place of Presentation
  学術総合センター中会議室3,4、東京
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Reexpression of hSNF5 regulates the transcriptional activity of the p21 promoter through p53 dependent or independent mechanisms in malignant rhabdoid tumors2011
- Author(s)
  Kuwahara Y, Durand J
- Organizer
  Weissman BE 102th American Association for Cancer Research Annual Meeting
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] hSNF5はp53依存性機序とp53非依存性機序でp21の転写を制御する2011
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  第5回日本エピジェネティック研究会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株におけるhSNF5によるp53標的遺伝子の発現制御のメカニズム2011
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Reexpression of hSNF5 regulates the transcriptional activity of the NOXA promoter through p53 independent mechanisms in malignant rhabdoid tumors2011
- Author(s)
  Kuwahara Y, Durand J, Weissman BE
- Organizer
  102st Annual Meeting American Association for Cancer Resarch
- Place of Presentation
  Orlando、Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Reexpression of hSNF5 regulates the transcriptional activity of the p21 promoter through p53 dependent or independent mechanisms in malignant rhabdoid tumors.2010
- Author(s)
  Y Kuwahara, B Davis, B Weissman
- Organizer
  101st Annual Meeting American Association for Cancer Research
- Place of Presentation
  Washington D.C.U.S.A
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株においてhSN F5はp21を介して細胞周期を制御する2010
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  第26回日本小児がん学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株においてhSNF5はp21を介して細胞周期を制御する2010
- Author(s)
  桑原康通、B Weissman、細井創
- Organizer
  第26回日本小児がん学会学術集会
- Place of Presentation
  大阪国際会議場(グランキューブ大阪)、大阪
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Is Additional Treatment Necessary for a Residual Tumor in Cases of Intermediate-Risk Neuroblastoma?．
- Author(s)
  Iehara T，Tsuchiya K，Yagyu S，Ouchi K，Katsumi Y，Kuwahara Y，Fumino S，Tajiri T，Hosoi H．
- Organizer
  Advances in neuroblastoma research ANR Congress 2014．
- Place of Presentation
  Cologne, Germany．
- Year and Date
  2014-05-13 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-26461591
[Presentation] Loss of NOXA expression by INI1/SNF5 loss impaired sensitivity to chemotherapeutic agents in malignant rhabdoid tumor in vitro and vivo
- Author(s)
  Kazutaka Ouchi, Yasumichi Kuwahara, Tomoko Iehara, Eiichi Konishi, Hajime Hosoi
- Organizer
  1st International rhabdoid tumor group meeting.
- Place of Presentation
  Paris, France
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-25461602
[Presentation] CLINICAL FINDINGS OF ONCOLOGIC EMERGENCY AT DIAGNOSIS.
- Author(s)
  T. Iehara, K. Tsuchiya , K. Ouchi , M. Miyachi , Y. Kuwahara , S. Fumino , T. Tajiri , H. Hosoi.
- Organizer
  46th Congressof the International Society of Paediatric Oncology
- Place of Presentation
  Tronto Cancad.
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26461591
[Presentation] Function analysis of NOXA expression in malignant rhabdoid tumor．
- Author(s)
  Ouchi K, Kuwahara Y、Tsuchiya K, Iehara T, Hosoi H．
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25461602

1. IEHARA Tomoko (20285266)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. Okuda Tsukasa (30291587)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
3. 菊地顕 (40453104)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. HOSOI Hajime (20238744)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. Katsumi Yoshiki (00808496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 宮地充 (40584983)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 吉田達士 (80315936)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. TSUCHIYA Kunihiko (90381938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 忠垣憲次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kuwahara Yasumichi 桑原 康通

KUWAHARA YASUMICHI 桑原 康通

KUWAHARA Yasumichi 〓原 康通

桑原 康通 クワハラ ヤスミチ

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Molecular Dissection of Acquired Therapy Resistance in Rhabdoid Tumors and the Development of Targeted Therapeutic InterventionsPrincipal Investigator

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Functional analysis of transcription factors and novel SWI/SNF complexes in the tumorigenesis of rhabdoid tumors.Principal Investigator

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Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.

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Elucidation of the molecular mechanisms of malignant rhabdoid tumors mediated by dysregulation of super-enhancer function.Principal Investigator

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Search for novel intervention methods for hematopoietic transcription control and research for its clinical application

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Identifying and analyzing biological characteristics of rhabdoid tumor stem cells to establish new treatment

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The clarification of a tumorigenesis of malignant rhabdoid tumor through a understanding of control mechanism of RUNX1 by hSNF5Principal Investigator

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Study of recurrence mechanism in super high-risk neuroblastoma

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The establishment of peptide vaccine as a consolidation therapy for childhood cancer.

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The Epigenome Analysis of the Mechanisms of Chemoresistance and Development new treatment in Rhabdoid TumorPrincipal Investigator

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The determination of the hSNF5 target genes and the clarification of the transcriptional mechanism of hSNF5Principal Investigator

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[Journal Article] Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors2023

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[Journal Article] C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO2022

Author(s)

Kuwahara Yasumichi 桑原康通

KUWAHARA YASUMICHI 桑原康通

KUWAHARA Yasumichi 〓原康通

桑原康通クワハラヤスミチ

[Journal Article] SNF5 reexpression in malignant rhabdoid tumors regulates transcription of target genes by recruitment of　SWI/SNF complexes and RNAPII to the transcription start site of their promoters．2013