Kuwahara Yasumichi 桑原康通

… Alternative Names

KUWAHARA YASUMICHI 桑原康通

KUWAHARA Yasumichi 〓原康通

桑原康通クワハラヤスミチ

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Researcher Number	30590327
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2025: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2022 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2015 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2013 – 2014: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2011: 京都府立医科大学, 医学研究科, 助教 2010 – 2011: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator ラブドイド腫瘍 / SWI/SNF複合体 / RUNX1 / SNF5 / 悪性ラブドイド腫瘍 / Mcl-1 / NOXA / TRKA / スーパーエンハンサー / SWI/SNF … More / RUNX / クロマチンリモデリング因子 / 転写制御 / Rhabdoid腫瘍 / クロマチン免疫沈降法 / 薬剤耐性 / アポトーシス / 薬剤感受性 / クロマチンリモデリング / p53 / p21 / hSNF5 … More Except Principal Investigator 翻訳後修飾 / 転写因子 / 造血発生 / 白血病 / Yeast Two-Hybrid / RUNX1 / 染色体転座 / クロマチンリモデリング / キナーゼ / リン酸化 / 造血幹細胞 / Yeast two-hybrid / Yeast two hybrid / C11orf21 / TRAIL / 転写調節 / 遺伝子改変マウス / 分子標的薬 / AML1 / 転写制御 / 造血器腫瘍 / INI1 / 新規治療 / SMARCB1 / 癌幹細胞 / がん幹細胞 / CD44 / survivin / FOXM1 / 幹細胞 / ラブドイド腫瘍 / 融合遺伝子 / PD-1 / PD-L1 / 免疫チェックポイント / 横紋筋肉腫 / 免疫療法 / 小児がん / 再発 / ｽｰﾊﾟｰﾊｲﾘｽｸ / ハイリスク / スーパーハイリスク / 神経芽腫 Less

ラブドイド腫瘍の治療抵抗性獲得にかかわる分子機構の解明と新規治療法の開発Principal Investigator
- Principal Investigator
  
  桑原康通
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Functional analysis of transcription factors and novel SWI/SNF complexes in the tumorigenesis of rhabdoid tumors.Principal Investigator
- Principal Investigator
  
  桑原康通
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the molecular mechanisms of malignant rhabdoid tumors mediated by dysregulation of super-enhancer function.Principal Investigator
- Principal Investigator
  
  Kuwahara Yasumichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Search for novel intervention methods for hematopoietic transcription control and research for its clinical application
- Principal Investigator
  
  Okuda Tsukasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Identifying and analyzing biological characteristics of rhabdoid tumor stem cells to establish new treatment
- Principal Investigator
  
  Katsumi Yoshiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
The clarification of a tumorigenesis of malignant rhabdoid tumor through a understanding of control mechanism of RUNX1 by hSNF5Principal Investigator
- Principal Investigator
  
  Kuwahara Yasumichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Study of recurrence mechanism in super high-risk neuroblastoma
- Principal Investigator
  
  Tomoko Iehara
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
The establishment of peptide vaccine as a consolidation therapy for childhood cancer.
- Principal Investigator
  
  Hosoi Hajime
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
The Epigenome Analysis of the Mechanisms of Chemoresistance and Development new treatment in Rhabdoid TumorPrincipal Investigator
- Principal Investigator
  
  KUWAHARA YASUMICHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
The determination of the hSNF5 target genes and the clarification of the transcriptional mechanism of hSNF5Principal Investigator
- Principal Investigator
  
  KUWAHARA Yasumichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors2023
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 15 Pages: 16323-16336
- DOI
  10.1002/cam4.6255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07941, KAKENHI-PROJECT-22K08483
[Journal Article] C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO2022
- Author(s)
  Matsumoto Akifumi、Yoshida Tatsushi、Shima Takahiro、Yamasaki Kenta、Tadagaki Kenjiro、Kondo Noriko、Kuwahara Yasumichi、Zhang Dong-Er、Okuda Tsukasa
- Journal Title
  
  BBA Advances
  
  Volume: 2 Pages: 100047-100047
- DOI
  10.1016/j.bbadva.2022.100047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846
[Journal Article] Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors2022
- Author(s)
  Shinohara Haruka、Sawado Rie、Nakagawa Makoto、Hattori Ayuna、Yamagata Kazutsune、Tauchi Kimiharu、Ito Jumpei、Kuwahara Yasumichi、Okuda Tsukasa、Ogawa Chitose、Kitabayashi Issay
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 27 Pages: 14-25
- DOI
  10.1016/j.omto.2022.09.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08483
[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand is a novel transcriptional target of runt-related transcription factor 12022
- Author(s)
  Yoshida Tatsushi、Yamasaki Kenta、Tadagaki Kenjiro、Kuwahara Yasumichi、Matsumoto Akifumi、Sofovic Adem、Kondo Noriko、Sakai Toshiyuki、Okuda Tsukasa
- Journal Title
  
  International Journal of Oncology
  
  Volume: 60 Issue: 1 Pages: 1-1
- DOI
  10.3892/ijo.2021.5296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] Novel Two MRT Cell Lines Established from Multiple Sites of a Synchronous MRT Patient2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara, Eisuke Ichise, Yoshiki Katsumi, Kazutaka Ouchi, Kunihiko Tsuchiya, Mitsuru Miyachi, Eiichi Konishi, Hiroyasu Sasajima, Satoaki Nakamura, Shigehisa Fumino, Tatsuro Tajiri, Pascal D Johann, Michael Fruhwald, Tsukasa Okuda, Hajime Hosoi
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 11 Pages: 6159-6170
- DOI
  10.21873/anticanres.14636
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08257, KAKENHI-PROJECT-19K08846, KAKENHI-PROJECT-19K09053, KAKENHI-PROJECT-19H03719
[Journal Article] A NOXA/MCL-1 Imbalance Underlies Chemoresistance of Malignant Rhabdoid Tumor Cells.2015
- Author(s)
  Ouchi K, Kuwahara Y, Iehara T, Miyachi M, Katsumi Y, Tsuchiya K, Konishi E, Yanagisawa A, Hosoi H.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 9999 Issue: 9 Pages: 1-9
- DOI
  10.1002/jcp.25293
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461602
[Journal Article] SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.2014
- Author(s)
  Wei D, Goldfarb D, Song S, Cannon C, Yan F, Sakellariou-Thompson D, Emanuele M, Major MB, Weissman BE, Kuwahara Y.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 12 Issue: 11 Pages: 1574-1585
- DOI
  10.1158/1541-7786.mcr-14-0005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461602
[Journal Article] SNF5 reexpression in malignant rhabdoid tumors regulates transcription of target genes by recruitment of　SWI/SNF complexes and RNAPII to the transcription start site of their promoters．2013
- Author(s)
  Kuwahara Y, Wei D, Durand J, Weissman BE．
- Journal Title
  
  Mol Cancer Res
  
  Volume: 11 Issue: 3 Pages: 251-260
- DOI
  10.1158/1541-7786.mcr-12-0390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461602
[Journal Article] Sensitivity of malignant rhabdoid tumor cell lines to PD0332991 is inverserly correlated with p16 expression2011
- Author(s)
  Katsumi Y, Iehara T, Miyachi M, Yagyu Y, Tsubai-Shimizu T, Kikuchi K, Tamura S, Itoh H, Kuwahara Y, Tsuchiya K, Kuroda H, Sugimoto T, Houghton PJ, Hosoi H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413 Pages: 62-68
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Role of the RUNX family in the NRTK1 gene regulation for neuroblastoma cells.2022
- Author(s)
  Aya Nakae, Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会
- Data Source
  KAKENHI-PROJECT-22K07941
[Presentation] Role of the RUNX family in the NRTK1 gene regulation for neuroblastoma cells.2022
- Author(s)
  Aya Nakae, Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会大会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] TRAIL is a novel target gene of RUNX1/AML1 transcription factor.2022
- Author(s)
  Tatsushi YOSHIDA, Kenta YAMASAKI, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Akifumi MATSUMOTO, Adem Ejub SOFOVIC, Noriko KONDO, Toshiyuki SAKAI, Tsukasa OKUDA
- Organizer
  第84回日本血液学会学術集会　（博多）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] Transcriptional regulation of G1-cyclin gene CCND1 by RUNX1 and its leukemia-related form RUNX1-ETO.2022
- Author(s)
  Yoshihito Shimizu, Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第45回日本分子生物学会年会（幕張）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] RUNX1 requires SNF5 for its functional cooperation with the chromatin remodeling complex, SWI/SNF.2022
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会大会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] A seaweed-derived compound that inhibits growth of acute myeloid leukemia cells.2021
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Yasumichi Kuwahara, Tsukasa Okuda.
- Organizer
  第80回日本癌学会学術総会（横浜）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Two New MRT Cell Lines Established from Multiple Sites of a Synchronous MRT with a Unique DNA Methylation Pattern.2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara,Yoshiki Katsumi, Kunihiko Tsuchiya　,Mitsuru Miyachi, Tatsuro Tajiri, Tatsushi Yoshida, Tsukasa Okuda, Hajime Hosoi
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08257
[Presentation] Two New MRT Cell Lines Established from Multiple Sites of a Synchronous MRT with a Unique DNA Methylation Pattern.2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara,Yoshiki Katsumi, Kunihiko Tsuchiya　,Mitsuru Miyachi, Tatsuro Tajiri, Tatsushi Yoshida, Tsukasa Okuda, Hajime Hosoi
- Organizer
  第79回日本癌学会学術総会（広島）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Identification of a novel RUNX1 target by public data re-analysis that is suppressed by RUNX1-ETO2019
- Author(s)
  Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Donger Zhang, Tsukasa Okuda
- Organizer
  第81回日本血液学会学術集会（東京）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Analysis of a novel transcriptional target gene of RUNX1.2019
- Author(s)
  Tatsushi YOSHIDA, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Toshiyuki SAKAI, and Tsukasa OKUDA
- Organizer
  第78回　日本癌学会学術総会（京都）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] 造血関連転写因子 RUNX1による制御遺伝子の探索2019
- Author(s)
  山崎健太、忠垣憲次郎、近藤則子、桑原康通、吉田達士、奥田司
- Organizer
  第42回日本分子生物学会年会（福岡）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Newly established MRT cell lines from multiple sites of a synchronous MRT patient2018
- Author(s)
  Yasumichi Kuwahara, Hajime Hosoi, Tsukasa Okuda
- Organizer
  International Rhabdoid Tumor Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] Functional interaction between SWI/SNF complex and a hematopoietic transcription factor in malignant rhabdoid tumor.2018
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenjiro Tadagaki　and Tsukasa Okuda
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] Mechanism of recruitment of SWI/SNF complex via interaction between SNF5 and transcription factor.2017
- Author(s)
  Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda
- Organizer
  2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会/第90回日本生化学会大会)
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] Loss of NOXA expression by INI1/SNF5 loss impaired sensitivity to chemotherapeutic agents in malignant rhabdoid tumor in vitro and iv vivo.2015
- Author(s)
  Ouchi K, Kuwahara Y, Iehara T, Konishi E, Hosoi H.
- Organizer
  106th American Association for Cancer Research Annual Meeting．
- Place of Presentation
  Philadelphia, PA，U.S.A．
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461602
[Presentation] Malignant Rhabdoid Tumor(悪性ラブドイド腫瘍: MRT)の最新治療と今後の課題:COG、EUの現況をふまえて2012
- Author(s)
  〓原康通, 勝見良樹、土屋邦彦、家原知子、細井創
- Organizer
  平成23年度日本ウィルムス腫瘍スタディ(JWiTS)研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株におけるhSNF5によるp53標的遺伝子の発現制御2011
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  平成22年度日本ウィルムス腫瘍スタディ(JWiTS)研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株におけるhSNF5によるp53標的遺伝子の発現制御2011
- Author(s)
  桑原康通、B Weissman、細井創
- Organizer
  日本Wilms腫瘍研究会
- Place of Presentation
  学術総合センター中会議室3,4、東京
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Reexpression of hSNF5 regulates the transcriptional activity of the p21 promoter through p53 dependent or independent mechanisms in malignant rhabdoid tumors2011
- Author(s)
  Kuwahara Y, Durand J
- Organizer
  Weissman BE 102th American Association for Cancer Research Annual Meeting
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] hSNF5はp53依存性機序とp53非依存性機序でp21の転写を制御する2011
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  第5回日本エピジェネティック研究会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株におけるhSNF5によるp53標的遺伝子の発現制御のメカニズム2011
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Reexpression of hSNF5 regulates the transcriptional activity of the NOXA promoter through p53 independent mechanisms in malignant rhabdoid tumors2011
- Author(s)
  Kuwahara Y, Durand J, Weissman BE
- Organizer
  102st Annual Meeting American Association for Cancer Resarch
- Place of Presentation
  Orlando、Florida, U.S.A
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Reexpression of hSNF5 regulates the transcriptional activity of the p21 promoter through p53 dependent or independent mechanisms in malignant rhabdoid tumors.2010
- Author(s)
  Y Kuwahara, B Davis, B Weissman
- Organizer
  101st Annual Meeting American Association for Cancer Research
- Place of Presentation
  Washington D.C.U.S.A
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株においてhSN F5はp21を介して細胞周期を制御する2010
- Author(s)
  〓原康通, Bernard Weissman、細井創
- Organizer
  第26回日本小児がん学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] 悪性ラブドイド腫瘍細胞株においてhSNF5はp21を介して細胞周期を制御する2010
- Author(s)
  桑原康通、B Weissman、細井創
- Organizer
  第26回日本小児がん学会学術集会
- Place of Presentation
  大阪国際会議場(グランキューブ大阪)、大阪
- Data Source
  KAKENHI-PROJECT-22890157
[Presentation] Is Additional Treatment Necessary for a Residual Tumor in Cases of Intermediate-Risk Neuroblastoma?．
- Author(s)
  Iehara T，Tsuchiya K，Yagyu S，Ouchi K，Katsumi Y，Kuwahara Y，Fumino S，Tajiri T，Hosoi H．
- Organizer
  Advances in neuroblastoma research ANR Congress 2014．
- Place of Presentation
  Cologne, Germany．
- Year and Date
  2014-05-13 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-26461591
[Presentation] Loss of NOXA expression by INI1/SNF5 loss impaired sensitivity to chemotherapeutic agents in malignant rhabdoid tumor in vitro and vivo
- Author(s)
  Kazutaka Ouchi, Yasumichi Kuwahara, Tomoko Iehara, Eiichi Konishi, Hajime Hosoi
- Organizer
  1st International rhabdoid tumor group meeting.
- Place of Presentation
  Paris, France
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-25461602
[Presentation] CLINICAL FINDINGS OF ONCOLOGIC EMERGENCY AT DIAGNOSIS.
- Author(s)
  T. Iehara, K. Tsuchiya , K. Ouchi , M. Miyachi , Y. Kuwahara , S. Fumino , T. Tajiri , H. Hosoi.
- Organizer
  46th Congressof the International Society of Paediatric Oncology
- Place of Presentation
  Tronto Cancad.
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26461591
[Presentation] Function analysis of NOXA expression in malignant rhabdoid tumor．
- Author(s)
  Ouchi K, Kuwahara Y、Tsuchiya K, Iehara T, Hosoi H．
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25461602

1. Okuda Tsukasa (30291587)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
2. IEHARA Tomoko (20285266)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. HOSOI Hajime (20238744)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. 菊地顕 (40453104)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 宮地充 (40584983)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 吉田達士 (80315936)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
7. TSUCHIYA Kunihiko (90381938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. Katsumi Yoshiki (00808496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 忠垣憲次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kuwahara Yasumichi 桑原 康通

KUWAHARA YASUMICHI 桑原 康通

KUWAHARA Yasumichi 〓原 康通

桑原 康通 クワハラ ヤスミチ

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ラブドイド腫瘍の治療抵抗性獲得にかかわる分子機構の解明と新規治療法の開発Principal Investigator

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Functional analysis of transcription factors and novel SWI/SNF complexes in the tumorigenesis of rhabdoid tumors.Principal Investigator

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Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.

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Elucidation of the molecular mechanisms of malignant rhabdoid tumors mediated by dysregulation of super-enhancer function.Principal Investigator

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Search for novel intervention methods for hematopoietic transcription control and research for its clinical application

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Identifying and analyzing biological characteristics of rhabdoid tumor stem cells to establish new treatment

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The clarification of a tumorigenesis of malignant rhabdoid tumor through a understanding of control mechanism of RUNX1 by hSNF5Principal Investigator

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Study of recurrence mechanism in super high-risk neuroblastoma

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The establishment of peptide vaccine as a consolidation therapy for childhood cancer.

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The Epigenome Analysis of the Mechanisms of Chemoresistance and Development new treatment in Rhabdoid TumorPrincipal Investigator

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The determination of the hSNF5 target genes and the clarification of the transcriptional mechanism of hSNF5Principal Investigator

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[Journal Article] Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors2023

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[Journal Article] C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO2022

Author(s)

Kuwahara Yasumichi 桑原康通

KUWAHARA YASUMICHI 桑原康通

KUWAHARA Yasumichi 〓原康通

桑原康通クワハラヤスミチ

[Journal Article] SNF5 reexpression in malignant rhabdoid tumors regulates transcription of target genes by recruitment of　SWI/SNF complexes and RNAPII to the transcription start site of their promoters．2013