Okamoto Ryo 岡本亮

… Alternative Names

OKAMOTO Ryo 岡本亮

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Researcher Number	30596870
Other IDs
Affiliation (Current)	2025: 成蹊大学, 理工学部, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 成蹊大学, 理工学部, 准教授 2023: 大阪大学, 大学院理学研究科, 准教授 2022: 大阪大学, 大学院理学研究科, 講師 2021: 大阪大学, 理学研究科, 講師 2017 – 2018: 大阪大学, 理学研究科, 講師 2016: 大阪大学, 理学研究科, 助教 2012 – 2015: 大阪大学, 理学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Bio-related chemistry / Basic Section 37010:Bio-related chemistry / Chemistry related to living body Except Principal Investigator Broad Section E
Keywords	Principal Investigator 糖タンパク質 / 化学合成 / ペプチド / タンパク質 / タンパク質化学合成 / グアニジド / ペプチド-グアニジド / ペプチドチオエステル / ペプチドグアニジド / グリコシル化 … More / CCL1 / RGD / ケモカイン / 水素重水素交換 / 糖ペプチド / 結合親和性 / 棟ペプチド / タンパク質間相互作用 / 水和 / 糖鎖 / 有機合成化学 / ペプチド化学 / タンパク質化学 / 糖質関連化学・糖鎖工学 / N-ピバロイルグアニジン / ピバロイルグアニジド / ピバロイルグアニジン / ネイティブケミカルライゲーション / ペプチドーピバロイルグアニジン / ワンポット / エリスロポエチン / ペプチドライゲーション / チオエステル / 水溶液 / カルバメート基 / 親水性保護基 / ヒドロキシルアミン / タンパク質合成 / カルバメート / ペプチド合成 / 偽-ラセミタンパク質結晶化法 / AFGP / 不凍糖タンパク質 / N-アセチルグアニジン / 結晶構造解析 … More Except Principal Investigator 膜貫通型糖タンパク質 / CryoEM / 水和 / 糖ペプチド / メルカプトアミノ酸 / チオアシッド / 水和水 / 糖鎖タグ / 糖水和 / タンパク質 / 糖鎖 / 糖タンパク質 / 糖鎖水和殻 Less

Development of efficient synthesis of glycoconjugates and elucidation of water-mediated regulation of glycoconjugate activityPrincipal Investigator
- Principal Investigator
  
  Okamoto Ryo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Osaka University
New Synthetic Methods for Glycoproteins and the Integrated Approaches to Elucidate the Functions of Post-translational Modifications
- Principal Investigator
  
  梶原康宏
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section E
- Research Institution
  The University of Osaka
Development of a new convergent one-pot peptide ligation for the facile synthesis of glycoproteins and its crystallographyPrincipal Investigator
- Principal Investigator
  
  Okamoto Ryo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
Development of a new peptide synthetic method using peptide-guanidide and peptide-thioesterPrincipal Investigator
- Principal Investigator
  
  Okamoto Ryo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
X-ray crystallography of quasi-racemic glycoprotein synthesized by chemical methodsPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Ryo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation Book Patent

[Book] 最新ペプチド合成技術とその創薬研究への応用2012
- Author(s)
  岡本　亮, 梶原　康宏
- Total Pages
  5
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24750161
[Journal Article] Rapid Chemical Synthesis of Serine Protease Inhibitor Kazal-type 13 (SPINK13) Glycoform by a Combined Method with Glycan Insertion Strategy and Fast-Flow Fmoc SPPS.2023
- Author(s)
  Nomura K, Okamoto R, Maki Y, Hayashibara A, Takao T, Fukuoka T, Miyoshi E, Pentelute BL, Kajihara Y.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 29 Issue: 42
- DOI
  10.1002/chem.202300646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H05028, KAKENHI-PROJECT-23K24228
[Journal Article] Semisynthesis of homogeneous misfolded glycoprotein interleukin-82023
- Author(s)
  Mamahit YP, Maki Y, Okamoto R, Kajihara Y.
- Journal Title
  
  Carbohydr Res.
  
  Volume: 531 Pages: 108847-108847
- DOI
  10.1016/j.carres.2023.108847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18215, KAKENHI-PROJECT-21H05028
[Journal Article] Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination2023
- Author(s)
  Akiyama Tatsunari, Tanaka Yusuke, Okamoto Ryo, Kajihara Yasuhiro, Izumi Masayuki
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 11 Pages: 1307254-1307254
- DOI
  10.3389/fchem.2023.1307254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05311, KAKENHI-PROJECT-21H05028
[Journal Article] Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis2023
- Author(s)
  R. Okamoto, R. Orii, H. Shibata, Y. Maki, S. Tsuda, Y. Kajihara
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 29 Issue: 21
- DOI
  10.1002/chem.202203553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H05028, KAKENHI-PROJECT-21K05276
[Journal Article] Recent advances on the synthesis of N-linked glycoprotein for the elucidation of glycan functions2023
- Author(s)
  Liu Yanbo、Nomura Kota、Abe Junpei、Kajihara Yasuhiro
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 73 Pages: 102263-102263
- DOI
  10.1016/j.cbpa.2023.102263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20J20649, KAKENHI-PROJECT-21H05028, KAKENHI-PROJECT-21K18215
[Journal Article] Convergent synthesis of proteins using peptide-aminothiazoline2023
- Author(s)
  Okamoto Ryo、Shibata Hiroyuki、Yatsuzuka Takahiro、Hanao Takuya、Maki Yuta、Kabayama Kazuya、Miura Ayane、Fukase Koichi、Kajihara Yasuhiro
- Journal Title
  
  Chemical Communications
  
  Volume: 59 Issue: 90 Pages: 13510-13513
- DOI
  10.1039/d3cc04387h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05276, KAKENHI-PROJECT-21K18215, KAKENHI-PROJECT-20H05675, KAKENHI-PROJECT-21H05028
[Journal Article] Design and Synthesis of Glycosylated Cholera Toxin B-Subunit as a Tracer of Glycoprotein Trafficking in Organelles of Living Cells2022
- Author(s)
  Y. Maki, K. Kawata, Y. Liu, K-Y. Goo, Ryo Okamoto, Y. Kajihara, A. Satoh
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 28 Issue: 37
- DOI
  10.1002/chem.202201253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H05028
[Journal Article] Semisynthesis of a homogeneous glycoprotein using chemical transformation of peptides to thioester surrogates2022
- Author(s)
  R. Okamoto, K. Iritani, Y. Amazaki, D. Zhao, C. Chandrashekar, Y. Maki, Y. Kanemitsu, T. Kaino, Y. Kajihara
- Journal Title
  
  J. Org. Chem.
  
  Volume: 87 Issue: 1 Pages: 114-124
- DOI
  10.1021/acs.joc.1c02031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H05028
[Journal Article] Isolation and characterization of high-mannose type glycans containing five or six mannose residues from hen egg yolk2022
- Author(s)
  Y. Maki, Y. Otani, R. Okamoto, M. Izumi, Y. Kajihara
- Journal Title
  
  Carbohydr. Res.
  
  Volume: 521 Pages: 108680-108680
- DOI
  10.1016/j.carres.2022.108680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H05028
[Journal Article] Optimization of Semisynthetic Approach for Glycosyl Interferon beta polypeptide by Utilizing Bacterial Protein Expression and Chemical Modification2022
- Author(s)
  Yie-Kie Chong, Chaitra Chandrashekar, Donglin Zhao, Yuta Maki, Ryo Okamoto, Yasuhiro Kajihara
- Journal Title
  
  Organic & Biology Chemistry
  
  Volume: 20 Issue: 9 Pages: 1907-1915
- DOI
  10.1039/d1ob02391h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18215, KAKENHI-PROJECT-21H05028
[Journal Article] Total Synthesis of O-GalNAcylated Antifreeze Glycoprotein using the Switchable Reactivity of Peptidyl-N-pivaloylguanidine2017
- Author(s)
  Orii Ryo、Sakamoto Noriko、Fukami Daichi、Tsuda Sakae、Izumi Masayuki、Kajihara Yasuhiro、Okamoto Ryo
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 23 Issue: 39 Pages: 9253-9257
- DOI
  10.1002/chem.201702243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K05844
[Journal Article] An efficient solid-phase synthesis of peptidyl-N-acetylguanidines for use in native chemical ligation2016
- Author(s)
  R. Okamoto, M. Isoe, M. Izumi, Y. Kajihara
- Journal Title
  
  Journal of Peptide Science
  
  Volume: - Issue: 5 Pages: 343-351
- DOI
  10.1002/psc.2872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26810092
[Patent] 糖鎖を利用する可溶化タグ2023
- Inventor(s)
  梶原康宏　岡本亮、真木勇太、Yanbo Liu
- Industrial Property Rights Holder
  大阪大学,　糖鎖工学研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21H05028
[Patent] 新規な溶媒試料調製用容器2023
- Inventor(s)
  梶原康宏　岡本亮、真木勇太、森口達也
- Industrial Property Rights Holder
  大阪大学,　糖鎖工学研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 化学合成法を利用したシアリル糖鎖とタンパク質間相互作用相関関係の解明研究2024
- Author(s)
  岩崎理沙、岡本亮、真木勇太、梶原康宏
- Organizer
  日本化学会第103春季年会 (2023)
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] タンパク質合成の効率化を指向したツールとしてβ メルカプトアミノ酸誘導体の合成と糖鎖タグの導入2024
- Author(s)
  阿部純平、藤岡侑美、三輪哲平、真木勇太、岡本亮、梶原康宏
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 新規ペプチド調製法を用いたインターロイキン２１の半合成研究2023
- Author(s)
  井澤奈々、真木勇太、岡本亮、梶原康宏
- Organizer
  第42回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Semisynthetic Study of Glycoprotein Interleukin-6 (IL-6)2023
- Author(s)
  Yanbo Liu, Ryo Okamoto, Yuta Maki, Yasuhiro Kajihara
- Organizer
  Eurocarbo2023, Paris
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Unique analysis of water behavior around glycans2023
- Author(s)
  Tatsuya Moriguch1, Yuta Maki, Ryo Okamoto, Yasuhiro Kajihara
- Organizer
  Glycobiology meeting, Hawaii
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] ペプチド型複合糖質に於ける糖の機能解明を志向した環状RGD糖ペプチド合成研究2023
- Author(s)
  山﨑久生、真木勇太、梶原康宏、岡本亮
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] Synthetic Study of Glycosyl-Stem Cell Factor Using β-mercapto Norleucine2023
- Author(s)
  森本梨緒、真木勇太、岡本亮、梶原康宏
- Organizer
  第42回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] フルオロアミノ酸を利用した疎水性糖タンパク質の合成研究2023
- Author(s)
  桜井遼太、岡本亮、真木勇太、梶原康宏
- Organizer
  日本化学会　第103春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Dissecting the hydration of glycans on proteins by using total chemical synthesis of glycoproteins2023
- Author(s)
  Ryo Okamoto, Hiroyuki Shibata, Ryo Orii, Yuta Maki, Kaoru Ishihara, Ayano Satoh, Sakae Tsuda and Yasuhiro Kajihara
- Organizer
  Eurocarb2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] フロー法を利用した糖ペプチド迅速合成2023
- Author(s)
  真木勇太、山口真太郎、岡本亮、Bradley L. Pentelute、梶原康宏
- Organizer
  第42回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Semi-synthetic Study of Glycoprotein Interleukin-6 (IL-6) via a Novel Folding-assisted Thioesterification Method2023
- Author(s)
  Yanbo Liu, Ryo Okamoto, Yuta Maki, Yasuhiro Kajihara
- Organizer
  The 60th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 多様なエリスロポエチングリコフォーム合成を可能とする糖ペプチド液相合成法の開発研究2023
- Author(s)
  森口達也・中村大地・Jui Wu・真木勇太・岡本亮・梶原康宏
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Synthetic Study of Glycosyl-Stem Cell Factor Using β-mercapto Norleucine2023
- Author(s)
  Rio Morimoto, Yuta Maki, Ryo Okamoto, Yasuhiro Kajihara
- Organizer
  Eurocarbo2023, Paris
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Efficient synthesis of glycopeptides and glycoproteins by flow-based peptide synthesis2023
- Author(s)
  Yuta Maki, Ryo Okamoto, Bradley L. Pentelute, Yasuhiro Kajihara
- Organizer
  Eurocarbo2023, Paris
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 小型人工糖タンパク質を利用した糖鎖とタンパク質間相互作用相関関係の解明研究2023
- Author(s)
  西川晴美、真木勇太、梶原康宏、岡本亮
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] フルオロアミノ酸を利用した疎水性糖タンパク質の合成研究2023
- Author(s)
  桜井遼太、岡本亮、真木勇太、梶原康宏
- Organizer
  第42回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Dissecting the hydration of glycans on proteins by using total chemical synthesis of glycoproteins2023
- Author(s)
  Ryo Okamoto, Hiroyuki Shibata, Ryo Orii, Yuta Maki, Kaoru Ishihara, Ayano Satoh, Sakae Tsuda, Yasuhiro Kajihara
- Organizer
  Eurocarbo2023, Paris
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 新規ペプチド調製法を用いたインターロイキン２１の半合成研究2023
- Author(s)
  井澤奈々、真木勇太、岡本亮、梶原康宏
- Organizer
  日本化学会　第103春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 新規チオエステル化法を利用した糖タンパク質の半合成研究2023
- Author(s)
  劉晏博,入谷健斗, 岡本亮, 真木勇太, 梶原康宏
- Organizer
  第65回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Study of Glycan Effect on Protein-Protein Interaction by Using Artificial Small Glycoproteins2023
- Author(s)
  Harumi Nishikawa, Ryo Okamoto, Yuta Maki, Yasuhiro Kajihara
- Organizer
  Glycobiology meeting, Hawaii
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 小型人工糖タンパク質の合成研究2023
- Author(s)
  西川晴美、岡本亮、真木勇太、梶原康宏
- Organizer
  日本化学会　第103春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 水分量を制御する新規サンプリング法による糖と水の相互作用解析2023
- Author(s)
  森口達也、真木勇太、岡本亮、梶原康宏
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 新規グライコタグを利用した糖タンパク質IL6の半合成2023
- Author(s)
  劉晏博, 岡本亮, 真木勇太, 梶原康宏
- Organizer
  第42回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Semisynthetic Study of Interleukin-21(IL-21) using Novel Peptide Preparation Method2023
- Author(s)
  Nana Izawa, Yuta Maki, Ryo Okamoto, Yasuhiro Kajihara
- Organizer
  Glycobiology meeting, Hawaii
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] β-メルカプトノルロイシンを利用した糖タンパク質 Stem Cell Factorの合成研究2023
- Author(s)
  森本梨緒、真木勇太、岡本亮、梶原康宏
- Organizer
  日本化学会　第103春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Synthetic study of Erythropoietin with diverse glycans2022
- Author(s)
  T. Moriguchi, D. Nakamura, J. Wu, Y. Maki, R. Okamoto, Y. Kajihara
- Organizer
  30th International Carbohydrate Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 新規β-メルカプトノルロイシン合成法の開発2022
- Author(s)
  森本梨緒、真木勇太、岡本亮、梶原康宏
- Organizer
  日本化学会第102回春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] β-メルカプトチロシン誘導体を利用した糖タンパク質IL-17Fの半合成研究2022
- Author(s)
  矢部勇人、岡本亮、真木勇太、梶原康宏
- Organizer
  日本化学会第102回春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Study of the hydration property of sialyloligosaccharides on proteins using homogeneous glycoproteins prepared by total chemical synthesis2022
- Author(s)
  Ryo Okamoto, Yuta Maki, Hiroyuki Shibata, Kaoru Ishihara, Yasuhiro Kajihara
- Organizer
  SIALOGLYCO2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] 糖タンパク質間相互作用解析を志向したフルオロアミノ酸誘導体の合成2022
- Author(s)
  桜井遼太、岡本亮、真木勇太、梶原康宏
- Organizer
  日本化学会　第102春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 化学的糖鎖挿入法を基盤としたIL21半合成研究2022
- Author(s)
  井澤奈々、真木勇太、岡本亮、梶原康宏
- Organizer
  日本化学会第102回春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 多様な糖鎖を持つエリスロポエチンの合成研究2022
- Author(s)
  森口達也、中村大地、Jui Wu、真木勇太、岡本亮、梶原康宏
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] β-メルカプトフェニルアラニン誘導体を利用した糖タンパク質MCP-1の新規半合成研究2022
- Author(s)
  奥田暁、岡本亮、真木勇太、梶原康宏
- Organizer
  日本化学会第102回春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] One-Pot Chemical Synthesis of Glycoproteins and Their Specific Glycan-Hydration Effect2022
- Author(s)
  Hiroyuki Shibata, Yuya Tanaka, Donglin Zhao, Yuta Maki, Yasuhiro Kajihara, Ryo Okamoto
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] Dissecting the hydration of glycans on proteins by using total chemical synthesis of glycoproteins2022
- Author(s)
  Ryo Okamoto
- Organizer
  International Congress on Pure & Applied Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] Semisynthesis of Homogeneous Intentionally Misfolded Glycoprotein IL-82022
- Author(s)
  Y. P. Mamahit, Y. Maki, R. Okamoto, Y. Kajihara
- Organizer
  The 102nd CSJ Annual Meeting
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Semisynthetic Study of Glycoprotein Interleukin-62022
- Author(s)
  Y. Liu, R. Okamoto, Y. Maki, Y. Kajihara
- Organizer
  The 102nd CSJ Annual Meeting
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Semisynthetic study of Interferon-β2022
- Author(s)
  Y. Yang, Y. Maki, R. Okamoto, Y. Kajihara
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Semisynthetic Study of glycoprotein Interleukin-62022
- Author(s)
  Y. Liu, R. Okamoto, Y. Maki, Y. Kajihara
- Organizer
  30th International Carbohydrate Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] タンパク質間相互作用における糖鎖機能再考2022
- Author(s)
  岡本　亮、真木　勇太、佐藤　あやの、梶原　康宏
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] Dissecting the hydration of glycans on proteins by using total chemical synthesis of glycoproteins2022
- Author(s)
  Ryo Okamoto, Yuta Maki, Hiroyuki Shibata, Ryo Orii, Kaoru Ishihara, Ayano Sato, Sakae Tsuda and Yasuhiro Kajihara
- Organizer
  International Carbohydrate Symposium 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] 複合型糖鎖を有する Cholera Toxin B-Subunit の化学合成と生細胞への導入2021
- Author(s)
  真木勇太, 佐藤あやの, 川田一希, 岡本亮, 梶原康宏
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] スレオニン部位を利用した新規糖タンパク質半合成法の開発研究2021
- Author(s)
  山田大貴, 真木勇太, 岡本亮, 梶原康宏
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Thioacid-Based Strategy for the Semisynthesis of Glycoproteins2021
- Author(s)
  K. Nomura, R. Okamoto, Y. Maki, Y. Kajihara
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] ミスフォールド型糖タンパク質 IL-8 の半合成研究2021
- Author(s)
  ママヒット・ユゴヴィアンディ・プリマンダ, 真木勇太, 岡本亮, 梶原康宏,
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] タンパク質糖鎖水和殻による水の動的挙動2021
- Author(s)
  岡本　亮、真木　勇太、芝田　大之、佐藤　あやの、梶原　康宏
- Organizer
  第40回　日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] 非天然型糖タンパク質を合成し天然型糖鎖の機能を探る2021
- Author(s)
  岡本　亮
- Organizer
  第８回　慶應有機化学若手シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] Chemical synthesis of an erythropoietin glycoform having a semisynthesized triantennary oligosaccharide and its biological evaluation2021
- Author(s)
  Y. Maki, R. Okamoto, M. Izumi, Y. Kajihara
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] 新規ワンポット法よる糖タンパクの化学合成と糖鎖の特異的水和の機能解明研究2021
- Author(s)
  芝田大之, 田中裕也, Donglin Zhao, 真木勇太, 梶原康宏, 岡本亮
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] タンパク質間相互作用時の糖鎖水和殻による水の動的挙動2021
- Author(s)
  岡本亮、真木勇太、芝田　大之、野村幸汰、石原薫、佐藤あやの、梶原康宏
- Organizer
  第63回　天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-21K05276
[Presentation] Uncovering the Latent Function of Hydration of Carbohydrates Tuning the Thermal Hysteresis Activity of Antifreeze Glycoprotein2021
- Author(s)
  H. Shibata, R. Orii, Y. Maki, D. Fukami, S. Tsuda, Y. Kajihara, R. Okamoto
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05028
[Presentation] Chemical synthesis and functional analysis of antifreeze glycoprotein for elucidation of the function of O-glycosylation2018
- Author(s)
  Ryo Okamoto
- Organizer
  Frontiers in peptide science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05844
[Presentation] ペプチドピバロイルグアニジド体を用いた新規ワンポットペプチド連結法の開発研究2018
- Author(s)
  花尾　卓哉、真木　勇太、梶原　康宏、岡本　亮
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-16K05844
[Presentation] Chemical Synthesis and Functional Analysis of Antifreeze Glycoprotein for Elucidation of the Function of O-Glycosylation2018
- Author(s)
  Ryo Okamoto
- Organizer
  Symposium for Stephen B.H.Kent
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05844
[Presentation] 非天然糖タンパク質を合成し天然型糖鎖の機能を探る2018
- Author(s)
  岡本　亮
- Organizer
  新学術領域「中分子戦略」「分子夾雑化学」ジョイントシンポジウム　第21回生命化学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K05844
[Presentation] Total Synthesis of O-GalNAcylated Antifreeze Glycoprotein Toward Elucidation of the Functional Role of O-GalNAcylation2018
- Author(s)
  Ryo Okamoto, Ryo Orii, Daichi Fukami, Sakae Tsuda, Masayuki Izumi, and Yasuhiro Kajihara
- Organizer
  29th International Carbohydrate Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05844
[Presentation] Total Chemical Synthesis of O-GalNAcylated Antifreeze Glycoprotein using the Switchable Reactivity of Peptidyl-N-pivaloylguanidine2017
- Author(s)
  Ryo Okamoto、Ryo Orii、Daichi Fukami、Sakae Tsuda、Masayuki Izumi、Yasuhiro Kajihara
- Organizer
  7th Chemical Protein Synthesis Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05844
[Presentation] Total chemical synthesis of O-GalNAcylated antifreeze glycoprotein using the switchable reactivity of peptidyl-N-pivaloylguanidine2017
- Author(s)
  Ryo Okamoto
- Organizer
  6th Modern Solid Phase Peptide Synthesis & its Applications Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05844
[Presentation] 水溶液中でのペプチド合成を目指した新規カルバメート型保護基の開発研究2016
- Author(s)
  小野絵美子、和泉雅之、岡本亮、梶原康宏
- Organizer
  日本化学会第96会春季年会
- Place of Presentation
  同志社大学
- Year and Date
  2016-03-25
- Data Source
  KAKENHI-PROJECT-26810092
[Presentation] Chemical synthesis of “racemic”antifreeze glycoprotein toward the X-ray crystallography of the highly O-glycosylated protein2015
- Author(s)
  Ryo Okamoto
- Organizer
  6th Chemical Protein Synthesis Meeting
- Place of Presentation
  St. Louis
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-26810092
[Presentation] 不凍糖タンパク質AFGPの合成研究2014
- Author(s)
  折井亮、岡本亮、和泉雅之、梶原康宏
- Organizer
  日本化学会第94会春季年会
- Place of Presentation
  名古屋大学
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] Development of a New Selective Activation Method of Peptide C-Terminus Using N- Acetylguanidine Based on Fmoc SPPS2013
- Author(s)
  Madoka Isoe, Ryo Okamoto, Masayuki Izumi and Yasuhiro Kajihara
- Organizer
  4^<th> Asia-pacific international peptide symposium/50th Japanese peptide symposium
- Place of Presentation
  Osaka
- Year and Date
  2013-11-06
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] 糖タンパク質化学合成のためのsmall chemistryの開発2013
- Author(s)
  岡本　亮
- Organizer
  天然物ケミカルバイオロジー：分子標的と活性制御地区シンポジウム
- Place of Presentation
  和光　理研
- Invited
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] Development of an Efficient Synthetic Method of Peptidyl-N-Acylguanidine Derivatives and its Application to Peptide Coupling from N to C-Terminus2013
- Author(s)
  Noriko Sakamoto, Ryo Okamoto, Masayuki Izumi and Yasuhiro Kajihara
- Organizer
  4^<th> Asia-pacific international peptide symposium/50th Japanese peptide symposium
- Place of Presentation
  Osaka
- Year and Date
  2013-11-06
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] 簡便なペプチドグアニジド誘導体合成法の開発2013
- Author(s)
  坂本典子、岡本亮、梶原康宏
- Organizer
  日本化学会第93会春季年会
- Place of Presentation
  立命館大学
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] 糖タンパク質化学合成のためのsmall chemistryの開発2013
- Author(s)
  岡本亮
- Organizer
  天然物ケミカルバイオロジー:分子標的と活性制御地区シンポジウム
- Place of Presentation
  理研(和光)
- Year and Date
  2013-03-16
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] Peptide-N-acetyl-guanidine: a new peptide derivative for chemical protein synthesis2013
- Author(s)
  岡本　亮
- Organizer
  4th Modern solid phase peptide synthesis
- Place of Presentation
  神戸 (ホテル舞子ビラ)
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] Peptidyl-M-acylguanidine : a neew peptide derivative for chemical protein synthesis2013
- Author(s)
  Ryo Okamoto, Madoka Isoe, Noriko Sakamoto, Masayuki Izumi, Yasuhiro Kajihara
- Organizer
  4^<th> modern solid phase peptide synthesis and its applications symposium
- Place of Presentation
  Kobe
- Year and Date
  2013-11-03
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] 簡便なペプチド-グアニジド誘導体合成法の開発2013
- Author(s)
  坂本典子、岡本亮、梶原康宏
- Organizer
  第９３回日本化学会春季年会
- Place of Presentation
  滋賀　立命館大学
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] N-アセチルグアニジンを利用したペプチドC末端の新規選択的活性化法の開発2013
- Author(s)
  磯江まどか、岡本亮、梶原康宏
- Organizer
  日本化学会第93会春季年会
- Place of Presentation
  立命館大学
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] N-アセチルグアニジンを利用したペプチドC-末端の新規選択的活性化法の開発2013
- Author(s)
  磯江まどか、岡本亮、梶原康宏
- Organizer
  第９３回日本化学会春季年会
- Place of Presentation
  滋賀　立命館大学
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] ペプチドグアニジド誘導体を利用した新しいペプチドケミストリーの開発2012
- Author(s)
  岡本亮、磯江まどか、坂本典子、和泉雅之、梶原康宏
- Organizer
  2012若手ペプチド夏の勉強会
- Place of Presentation
  大阪
- Year and Date
  2012-08-06
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] 簡便なペプチドグアニジド誘導体合成法の開発研究2012
- Author(s)
  坂本典子、岡本亮、梶原康宏
- Organizer
  2012若手ペプチド夏の勉強会
- Place of Presentation
  大阪
- Year and Date
  2012-08-06
- Data Source
  KAKENHI-PROJECT-24750161
[Presentation] ペプチドグアニジド誘導体を利用した新しいペプチドケミストリーの開発2012
- Author(s)
  岡本　亮
- Organizer
  ペプチド夏の若手の会
- Place of Presentation
  大阪　ロッジ舞洲
- Data Source
  KAKENHI-PROJECT-24750161

1. 梶原康宏 (50275020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 47 results
2. 武田陽一 (20423973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 佐藤あやの (40303002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 和泉雅之 (80332641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 川本晃大 (90631523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Okamoto Ryo 岡本 亮

OKAMOTO Ryo 岡本 亮

Research Projects

Research Products

Co-Researchers

Development of efficient synthesis of glycoconjugates and elucidation of water-mediated regulation of glycoconjugate activityPrincipal Investigator

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New Synthetic Methods for Glycoproteins and the Integrated Approaches to Elucidate the Functions of Post-translational Modifications

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Development of a new convergent one-pot peptide ligation for the facile synthesis of glycoproteins and its crystallographyPrincipal Investigator

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Development of a new peptide synthetic method using peptide-guanidide and peptide-thioesterPrincipal Investigator

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X-ray crystallography of quasi-racemic glycoprotein synthesized by chemical methodsPrincipal Investigator

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[Book] 最新ペプチド合成技術とその創薬研究への応用2012

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[Journal Article] Rapid Chemical Synthesis of Serine Protease Inhibitor Kazal-type 13 (SPINK13) Glycoform by a Combined Method with Glycan Insertion Strategy and Fast-Flow Fmoc SPPS.2023

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[Journal Article] Semisynthesis of homogeneous misfolded glycoprotein interleukin-82023

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[Journal Article] Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination2023

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[Journal Article] Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis2023

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[Journal Article] Recent advances on the synthesis of N-linked glycoprotein for the elucidation of glycan functions2023

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[Journal Article] Convergent synthesis of proteins using peptide-aminothiazoline2023

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[Journal Article] Design and Synthesis of Glycosylated Cholera Toxin B-Subunit as a Tracer of Glycoprotein Trafficking in Organelles of Living Cells2022

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[Journal Article] Semisynthesis of a homogeneous glycoprotein using chemical transformation of peptides to thioester surrogates2022

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Okamoto Ryo 岡本亮

OKAMOTO Ryo 岡本亮