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Dohmoto Yukako  堂本 裕加子 (新谷 裕加子)

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Domoto Yukako  堂本 裕加子

新谷裕加子

SHINTANI Yukako  新谷 裕加子

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Researcher Number 30596961
Other IDs
Affiliation (Current) 2022: 日本医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2020: 日本医科大学, 医学部, 講師
2013 – 2019: 東京大学, 医学部附属病院, 助教
2016: 東京大学, 医学部附属病院, 特任講師
Review Section/Research Field
Principal Investigator
Human pathology / Laboratory medicine / Basic Section 49020:Human pathology-related
Keywords
Principal Investigator
プロテオミクス / 質量解析 / アミロイドーシス / 質量分析法 / 心筋症 / デスミン / 質量分析 / 質量顕微鏡 / 心臓 / プロテオミクス解析 … More / 左室補助人工心臓 / アミロイド前駆蛋白質 / 絶対定量 / 同位体ペプチド / 病理学 / 蛋白質 / 循環器・高血圧 / リピドーム Less
  • Research Projects

    (4 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (16 People)
  •  The Elucidation of the mechanism of amyloid deposition by combining proteome and lipidomePrincipal Investigator

    • Principal Investigator
      堂本 裕加子 (新谷裕加子)
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Nippon Medical School
  •  Absolute quantification of amyloid precursor proteins using mass spectrometryPrincipal Investigator

    • Principal Investigator
      Domoto Yukako
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  Proteomic analysis of the failing human heart by mass spectrometryPrincipal Investigator

    • Principal Investigator
      Domoto Yukako
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
      Laboratory medicine
    • Research Institution
      The University of Tokyo
  •  Analysis of the desmin deposition in the myocardiumPrincipal Investigator

    • Principal Investigator
      SHINTANI Yukako
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2017 2016 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] Poor Myocardial Compaction in a Patient with Recessive <i>MYL2</i> Myopathy2021

    • Author(s)
      Tamamitsu Ayaka Monoi、Nakagama Yu、Domoto Yukako、Yoshida Kenichi、Ogawa Seishi、Hirono Keiichi、Shindo Takahiro、Ogawa Yosuke、Nakano Katsutoshi、Asakai Hiroko、Hirata Yoichiro、Matsui Hikoro、Inuzuka Ryo
    • Journal Title

      International Heart Journal

      Volume: 62 Issue: 2 Pages: 445-447

    • DOI

      10.1536/ihj.20-639

    • NAID

      130008007427

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07389, KAKENHI-PROJECT-20K08177, KAKENHI-PROJECT-19K23992, KAKENHI-PROJECT-19H05656
  • [Journal Article] Glomerular Classification Using Convolutional Neural Networks Based on Defined Annotation Criteria and Concordance Evaluation Among Clinicians2021

    • Author(s)
      Yamaguchi Ryohei、Kawazoe Yoshimasa、Shimamoto Kiminori、Shinohara Emiko、Tsukamoto Tatsuo、Shintani-Domoto Yukako、Nagasu Hajime、Uozaki Hiroshi、Ushiku Tetsuo、Nangaku Masaomi、Kashihara Naoki、Shimizu Akira、Nagata Michio、Ohe Kazuhiko
    • Journal Title

      Kidney International Reports

      Volume: 6 Pages: 716-726

    • DOI

      10.1016/j.ekir.2020.11.037

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07389, KAKENHI-PROJECT-18H02828
  • [Journal Article] Renal Effects after Pembrolizumab Treatment for Non-small Cell Lung Carcinoma2020

    • Author(s)
      Oki R, Hirakawa Y, Kimura H, Honda K, Hinata M, Abe H, Domoto Y, Tanaka G, Nagase T, Nangaku M.
    • Journal Title

      Internal Medicine

      Volume: 59 Issue: 7 Pages: 977-981

    • DOI

      10.2169/internalmedicine.3928-19

    • NAID

      130007825319

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08717, KAKENHI-PROJECT-20K07389
  • [Journal Article] Use of a Non-invasive Cardiac Output Measurement in a Patient with Low-output Dilated Cardiomyopathy2020

    • Author(s)
      Nakayama Atsuko、Iwama Kentaro、Makise Naohiro、Domoto Yukako、Ishida Junichi、Morita Hiroyuki、Komuro Issei
    • Journal Title

      Internal Medicine

      Volume: March Issue: 12 Pages: 1525-1530

    • DOI

      10.2169/internalmedicine.4271-19

    • NAID

      130007854981

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K19828, KAKENHI-PROJECT-17K08717
  • [Journal Article] Mass spectrometry-based absolute quantification of amyloid proteins in pathology tissue specimens: Merits and limitations2020

    • Author(s)
      Makiko Ogawa, Yukako Shintani-Domoto, Yoshiki Nagashima, Koji L Ode, Aya Sato, Yoshihiro Shimizu, Kenichi Ohashi, Michael H A Roehrl, Tetsuo Ushiku, Hiroki R Ueda, Masashi Fukayama
    • Journal Title

      PLOSONE

      Volume: 7

    • DOI

      10.1371/journal.pone.0235143

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07389
  • [Journal Article] Case of aquagenic urticaria: Case report and the results of histopathological examination2020

    • Author(s)
      Fukayama Maiko、Domoto Yukako、Sato Shinichi、Asano Yoshihide
    • Journal Title

      The Journal of Dermatology

      Volume: 48 Pages: 88-91

    • DOI

      10.1111/1346-8138.15615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07389
  • [Journal Article] Quantification of DNA damage in heart tissue as a novel prediction tool for therapeutic prognosis of patients with dilated cardiomyopathy.2019

    • Author(s)
      Ko T, Fujita K, Nomura S, Uemura Y, Yamada S, Tobita T, Katoh M, Satoh M, Ito M, Domoto Y, Hosoya Y, Amiya E, Hatano M, Morita H, Fukayama M, Aburatani H, Komuro I.
    • Journal Title

      JACC: Basic to Translational Science

      Volume: 4 Pages: 670-680

    • DOI

      10.1016/j.jacbts.2019.05.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-17H04061, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-17K08717
  • [Journal Article] Clinical and Pathological Characteristics of IgG4-Related Periaortitis/Periarteritis and Retroperitoneal Fibrosis Diagnosed Based on Experts’ Diagnosis2019

    • Author(s)
      Mizushima Ichiro、Kasashima Satomi、Fujinaga Yasunari、Notohara Kenji、Saeki Takako、Zen Yoh、Inoue Dai、Yamamoto Motohisa、Kasashima Fuminari、Matsumoto Yasushi、Amiya Eisuke、Sato Yasuharu、Yamada Kazunori、Domoto Yukako、Kawa Shigeyuki、Kawano Mitsuhiro、Ishizaka Nobukazu
    • Journal Title

      Ann Vasc Dis

      Volume: 12 Issue: 4 Pages: 460-472

    • DOI

      10.3400/avd.oa.19-00085

    • NAID

      130007772896

    • ISSN
      1881-641X, 1881-6428
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09999, KAKENHI-PROJECT-19K17904, KAKENHI-PROJECT-17K08717, KAKENHI-PROJECT-16K19597
  • [Journal Article] Enormous Aneurysm in Coronary Artery Fistula With Immunoglobulin G4?Related Disease2019

    • Author(s)
      Kadowaki H. et al
    • Journal Title

      Canadian Journal of Cardiology

      Volume: 2

    • DOI

      10.1016/j.cjca.2018.11.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08717, KAKENHI-PROJECT-17K09488
  • [Journal Article] The pseudo-SAH sign: an imaging pitfall in postmortem computed tomography.2017

    • Author(s)
      Shirota G, Gonoi W, Ikemura M, Ishida M, Shintani Y, Abe H, Fukayama M, Higashida T, Okuma H, Abe O.
    • Journal Title

      International journal of legal medicine

      Volume: 131 Pages: 1647-1653

    • DOI

      10.1007/s00414-017-1651-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08717, KAKENHI-PROJECT-17K17644
  • [Journal Article] Intestinal perforation after nivolumab immunotherapy for a malignant melanoma: a case report.2017

    • Author(s)
      Yasuda K, Tanaka T, Ishihara S, Otani K, Nishikawa T, Kiyomatsu T, Kawai K, Hata K, Nozawa H, Masui Y, Shintani Y, Watanabe T.
    • Journal Title

      Surg Case Rep.

      Volume: 3 Pages: 94-94

    • DOI

      10.1186/s40792-017-0370-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08717
  • [Journal Article] Laminar crystal deposition in large vessels in a patient with crystalglobulinemia2017

    • Author(s)
      Yukako Shintani-Domoto, Aya Shinozaki-Ushiku, Hidemi Okuma, Mineo Kurokawa and Masashi Fukayama
    • Journal Title

      Pathology International

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Journal Article] Perforation of jejunal diverticulum with ectopic pancreas.2017

    • Author(s)
      Shiratori H, Nishikawa T, Shintani Y, Murono K, Sasaki K, Yasuda K, Otani K, Tanaka T, Kiyomatsu T, Hata K, Kawai K, Nozawa H, Ishihara S, Fukayama M, Watanabe T.
    • Journal Title

      Clin J Gastroenterol.

      Volume: 10 Pages: 137-141

    • DOI

      10.1007/s12328-017-0712-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08717
  • [Journal Article] Different desmin peptides are distinctly deposited in cytoplasmic aggregations and cytoplasm of desmin-related cardiomyopathy patients2017

    • Author(s)
      Yukako Shintani-Domoto, Takahiro Hayasaka, Daichi Maeda, Noritaka Masaki, Takashi K. Ito, Kei Sakuma, Michio Tanaka, Katsuya Kabashima, Shiro Takei, Mitsutoshi Setou, Masashi Fukayama
    • Journal Title

      BBA - Proteins and Proteomics

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Journal Article] Comparison of the cardiothoracic ratio between postmortem and antemortem computed tomography.2017

    • Author(s)
      Okuma H, Gonoi W, Ishida M, Shirota G, Kanno S, Shintani Y, Abe H, Fukayama M, Ohtomo K.
    • Journal Title

      Leg Med (Tokyo)

      Volume: 24 Pages: 86-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Journal Article] Implantation of a Left Ventricular Assist Device for Danon ardiomyopathy.2017

    • Author(s)
      Kitahara H, Nawata K, Kinoshita O, Itoda Y, Shintani Y, Fukayama M, Ono M.
    • Journal Title

      Ann Thorac Surg.

      Volume: 103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Journal Article] Successful bridge to recovery in fulminant myocarditis using a biventricular assist device: a case report.2017

    • Author(s)
      Adachi Y, Kinoshita O, Hatano M, Shintani Y, Naito N, Kimura M, Nawata K, Nitta D, Maki H, Ueda K, Amiya E, Takimoto E, Komuro I, Ono M.
    • Journal Title

      J Med Case Rep.

      Volume: 11 Pages: 295-295

    • DOI

      10.1186/s13256-017-1466-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08717
  • [Journal Article] Phenotypic differences in aortic stenosis according to calcification grade.2016

    • Author(s)
      Takata M, Amiya E, Watanabe M, Shintani Y, Sakuma K, Saito A, Fukayama M, Ono M, Komuro I.
    • Journal Title

      Int J Cardiol.

      Volume: 216 Pages: 118-120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Journal Article] Fukutin gene mutations that cause left ventricular noncompaction.2016

    • Author(s)
      Amiya E, Morita H, Hatano M, Nitta D, Hosoya Y, Maki H, Motozawa Y, Sato N, Ishiura H, Numakura S, Shintani Y, Kinugawa K, Takeda N, Shimizu J, Tsuji S, Komuro I.
    • Journal Title

      Int J Cardiol.

      Volume: 222 Pages: 727-729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Journal Article] Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis.2016

    • Author(s)
      Akiyama Y, Morikawa T, Maeda D, Shintani Y, Niimi A, Nomiya A, Nakayama A, Igawa Y, Fukayama M, Homma Y.
    • Journal Title

      Sci Rep

      Volume: 24 Pages: 28652-28652

    • NAID

      120007089053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Journal Article] Early postmortem volume reduction of adrenal gland: initial longitudinal computed tomographic study.2014

    • Author(s)
      Ishida M, Gonoi W, Hagiwara K, Okuma H, Shirota G, Shintani Y, Abe H, Takazawa Y, Fukayama M, Ohtomo K
    • Journal Title

      Radiol Med

      Volume: ?

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Journal Article] Comparison of attenuation of striated muscle between postmortem and antemortem computed tomography: results of a longitudinal study2014

    • Author(s)
      Okuma H, Gonoi W, Ishida M, Shirota G, Shintani Y, Abe H, Fukayama M, Ohtomo K
    • Journal Title

      PLoS One

      Volume: 11

    • DOI

      10.1371/journal.pone.0111457

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Journal Article] Pulmonary lymphocyte-rich classical Hodgkin lymphoma with early response to ABVD therapy2014

    • Author(s)
      Honda A, Nakamura F, Nannya Y, Shintani Y, Fukayama M, Ichikawa M, and Kurokawa M.
    • Journal Title

      Annals of Hematology

      Volume: 93 Pages: 1073-1074

    • DOI

      10.1007/s00277-013-1935-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-25860264
  • [Journal Article] Greater thickness of the aortic wall on postmortem computed tomography compared with antemortem computed tomography: the first longitudinal study2014

    • Author(s)
      Okuma H, Gonoi W, Ishida M, Shintani Y, Takazawa Y, Fukayama M, Ohtomo K
    • Journal Title

      Int J Legal Med

      Volume: 6 Pages: 987-993

    • DOI

      10.1007/s00414-013-0955-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Journal Article] A representative case of hereditary transthyretin amyloidosis complicated by intramyocardial hemorrhage2014

    • Author(s)
      Yagi H, Amiya E, Shintani Y, Nitta D, Numakura S, Hosoya Y, Watanabe M, Fukayama M, Komuro I
    • Journal Title

      Amyloid

      Volume: 1 Pages: 1-3

    • DOI

      10.3109/13506129.2014.987865

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Journal Article] Fluid in the airway of nontraumatic death on postmortem computed tomography: relationship with pleural effusion and postmortem elapsed time2014

    • Author(s)
      Ishida M, Gonoi W, Hagiwara K, Okuma H, Shintani Y, Abe H, Takazawa Y, Ohtomo K, Fukayama M
    • Journal Title

      Am J Forensic Med Pathol

      Volume: 2 Pages: 113-117

    • DOI

      10.1097/paf.0000000000000083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Journal Article] Heart wall is thicker on postmortem computed tomography than on ante mortem computed tomography: the first longitudinal study2013

    • Author(s)
      Okuma H1, Gonoi W, Ishida M, Shintani Y, Takazawa Y, Fukayama M, Ohtomo K
    • Journal Title

      PLoS One

      Volume: Sep 27;8(9) Pages: 1-8

    • DOI

      10.1371/journal.pone.0076026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Presentation] 左室補助人工心臓装着前後における心筋蛋白質のプロテオミクス Proteomic analysis of the failing human heart after left ventricular assist device support2020

    • Author(s)
      堂本裕加子、大出晃士、永島良樹、木下修、阿部浩幸、小野稔、上田泰己、牛久哲男、深山正久
    • Organizer
      第109回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-20K07389
  • [Presentation] 絶対定量的質量分析法を用いたアミロイドーシス30症例の検討2019

    • Author(s)
      堂本裕加子、 小川真喜子、 永島良樹、 大出晃士、 清水義宏、 上田泰己、 深山正久
    • Organizer
      第108回 日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K08717
  • [Presentation] 絶対定量的質量分析法を用いたアミロイド前駆蛋白質の同定2019

    • Author(s)
      堂本裕加子
    • Organizer
      第108回日本病理学会
    • Data Source
      KAKENHI-PROJECT-17K08717
  • [Presentation] Proteomic analysis of the failing human heart after left ventricular assist device support2016

    • Author(s)
      Yukako Shintani, Koji Ode, Yoshiki Nagashima, Osamu Kinoshita, Hiroyuki Abe, Minoru Ono, Hiroki R. Ueda, Masashi Fukayama
    • Organizer
      International Society For Rotary Blood Pumps
    • Place of Presentation
      Mito
    • Year and Date
      2016-09-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Presentation] 左室補助人工心臓装着前後の心筋蛋白の質量解析2016

    • Author(s)
      新谷裕加子
    • Organizer
      日本病理学会
    • Place of Presentation
      仙台国際センター(仙台市青葉区)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K20942
  • [Presentation] Utility of Imaging Mass Spectrometry for Detection of Abnormal Myocardial Desmin Deposition-Analysis of Desmin-related Cardiomyopathy and other Cardiac Diseases2014

    • Author(s)
      Yukako Shintani, Takahiro Hayasaka, Daichi Maeda, Michio Tanaka, Mitsutoshi Setou, Masashi Fukayama
    • Organizer
      The 103rd The USCAP annual meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Presentation] 心筋炎後拡張型心筋症例についての病理組織学的検討2013

    • Author(s)
      新谷 裕加子, 高澤 豊, 深山 正久
    • Organizer
      第102回病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Presentation] 近位尿細管上皮細胞内に針状結晶を認めた Fanconi症候群の父娘例

    • Author(s)
      新谷裕加子
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-04 – 2014-07-06
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Presentation] Transplant glomerulopathyの組織像を呈した腎移植後超長期の一例

    • Author(s)
      新谷 裕加子,阿部 浩幸,山野 水紀,池田 洋一郎,浜崎 敬文,藤乘 嗣泰,山口 裕,深山 正久
    • Organizer
      第17回移植腎病理研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25860264
  • [Presentation] 質量顕微鏡を用いたデスミン心筋症のイメージング

    • Author(s)
      新谷裕加子, 早坂孝宏, 前田大地, 田中道雄, 瀬藤光利, 深山 正久
    • Organizer
      第103回病理学会総会
    • Place of Presentation
      広島
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25860264
  • 1.  AMIYA Eisuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  犬塚 亮
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    # of Collaborated Products: 1 results
  • 3.  松井 彦郎
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    # of Collaborated Products: 1 results
  • 4.  小川 誠司
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    # of Collaborated Products: 1 results
  • 5.  五ノ井 渉
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    # of Collaborated Products: 1 results
  • 6.  中山 敦子
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    # of Collaborated Products: 1 results
  • 7.  野村 征太郎
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  • 8.  小室 一成
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  • 9.  森田 啓行
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  • 10.  黒川 峰夫
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  • 11.  柏原 直樹
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  • 12.  長洲 一
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  • 13.  川野 充弘
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  • 14.  山田 和徳
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    # of Collaborated Products: 1 results
  • 15.  原 怜史
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    # of Collaborated Products: 1 results
  • 16.  水島 伊知郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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