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oonishi chie  大西 千恵

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Onishi Chie  大西 千恵

ONISHI CHIE  大西 千恵

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Researcher Number 30598115
Other IDs
Affiliation (Current) 2025: 島根大学, 医学部, 特別協力研究員
Affiliation (based on the past Project Information) *help 2018: 島根大学, 学術研究院医学・看護学系, 助教
2016 – 2017: 島根大学, 医学部, 助教
2012 – 2014: 島根大学, 医学部, 医科医員
Review Section/Research Field
Principal Investigator
Pediatrics
Keywords
Principal Investigator
ITD-FLT3 / ROCK / ULBP1 / CXCL12 / ROCK1 / 治療抵抗性 / FLT3阻害剤 / 白血病 / FLT3-ITD / 白血病髄外浸潤 … More / 過剰細胞遊走 / Rock / ITD-Flt3変異 / CXCR4 / SDF1(CXCL12) / migration / 細胞遊走 / ITD-Flt3変異 / 急性骨髄性白血病 Less
  • Research Projects

    (2 results)
  • Research Products

    (3 results)
  •  Molecular characterization of ROCK leukemia between leukemia cells and endothelial cells in CNS leukemiaPrincipal Investigator

    • Principal Investigator
      Onishi Chie
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Shimane University
  •  Characterization of ROCK and new therapeutic strategy for extramedullary leukemiaPrincipal Investigator

    • Principal Investigator
      ONISHI CHIE
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Shimane University

All 2014 2013 2012

All Journal Article Presentation

  • [Journal Article] Internal Tandem Duplication Mutations in FLT3 Gene augment Chemotaxis to Cxcl12 Protein by Blocking the Down-regulation of the Rho-associated Kinase via the Cxcl12/Cxcr4 Signaling Axis2014

    • Author(s)
      Chie Onishi, Satomi Mori-Kimachi, Tomohiro Hirade, Mariko Abe, Takeshi Taketani, Junji Suzumiya, Toshitsugu Sugimoto, Seiji Yamaguchi, Reuben Kapur, Seiji Fukuda
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 289 Pages: 31053-31065

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24791064
  • [Presentation] ITD-Flt3 accentuates cell migration by antagonizing the reduction of ROCK1 induced by SDF12013

    • Author(s)
      大西千恵
    • Organizer
      日本血液学会
    • Place of Presentation
      北海道 札幌 さっぽろ芸文館
    • Data Source
      KAKENHI-PROJECT-24791064
  • [Presentation] The Internal-Tandem-Duplication of Flt3 Mutations Augment Chemotaxis in Hematopoietic Cells2012

    • Author(s)
      Chie Onishi
    • Organizer
      54th American Society of Hematology Annual Meeting and Exposition
    • Place of Presentation
      アメリカ アトランタ
    • Data Source
      KAKENHI-PROJECT-24791064

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