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Yoshida Tomomi  吉田 智美

ORCIDConnect your ORCID iD *help
… Alternative Names

吉田 智美  ヨシダ トモミ

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Researcher Number 30610216
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立国際医療研究所, 研究員
Affiliation (based on the past Project Information) *help 2023: 国立研究開発法人国立国際医療研究センター, 研究所・脂質生命科学研究部, 研究員
2016 – 2017: 国立研究開発法人国立国際医療研究センター, その他部局等, 上級研究員
2016: 国立国際医療研究センター, 上級研究員
2016: 国立国際医療研究センター, 脂質シグナリングプロジェクト, 上級研究員
2015: 国立研究開発法人国立国際医療研究センター, その他部局等, その他
2014: 独立行政法人国立国際医療研究センター, その他部局等, その他
Review Section/Research Field
Principal Investigator
Embryonic/Neonatal medicine / General medical chemistry
Except Principal Investigator
Basic Section 51030:Pathophysiologic neuroscience-related / General medical chemistry / Pathological medical chemistry
Keywords
Principal Investigator
生体膜リン脂質 / 胸腺分化 / 胸腺 / リン脂質 / 発生医学
Except Principal Investigator
リン脂質 / 生体膜 / リピドミクス / アラキドン酸 / LPCAT3 … More / 神経障害性疼痛 / 疼痛 / 脂質メディエーター / リゾリン脂質アシル転移酵素 / 生化学 / 質量分析計 / メタボロミクス / 疾患モデル / エイコサノイド / アシル転移酵素 / 脂質可視化 / トリグリセリド輸送 / 肺サーファクタント / ドコサヘキサエン酸 / アシル転位酵素 / グリセロリン脂質 Less
  • Research Projects

    (5 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (24 People)
  •  アラキドン酸含有リン脂質が担う難治性疼痛の新しい病態メカニズム

    • Principal Investigator
      山本 将大
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Kyushu University
  •  Analysis of phospholipid metabolism for thymus functionPrincipal Investigator

    • Principal Investigator
      YOSHIDA TOMOMI
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      National Center for Global Health and Medicine
  •  Elucidation of phospholipid metabolism necessary for lifePrincipal Investigator

    • Principal Investigator
      Yoshida Tomomi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      National Center for Global Health and Medicine
  •  Analysis of biological function regulated by membrane phospholipid diversity

    • Principal Investigator
      SHINDOU Hideo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      National Center for Global Health and Medicine
  •  Biology of diversity and asymmetry of membrane lipids

    • Principal Investigator
      Shimizu Takao
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Center for Global Health and Medicine
      The University of Tokyo

All 2024 2023 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Macrophage/microglia-producing transient increase of platelet-activating factor is involved in neuropathic pain2024

    • Author(s)
      Yamamoto Shota、Hashidate-Yoshida Tomomi、Yoshinari Yuki、Shimizu Takao、Shindou Hideo
    • Journal Title

      iScience

      Volume: - Issue: 4 Pages: 109466-109466

    • DOI

      10.1016/j.isci.2024.109466

    • Data Source
      KAKENHI-PROJECT-23K06820, KAKENHI-PROJECT-22KJ3239
  • [Journal Article] 1.Lysophosphatidylcholine acyltransferase 4 is involved in chondrogenic differentiation of ATDC5 cells.2017

    • Author(s)
      Tabe S, Hikiji H, Ariyoshi W, Hashidate-Yoshida T, Shindou H, Shimizu T, Okinaga T, Seta Y, Tominaga K, Nishihara T.
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-017-16902-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21651, KAKENHI-PROJECT-16H05545, KAKENHI-PROJECT-15K11018
  • [Journal Article] Lysophosphatidylethanolamine acyltransferase 1/membrane bound O-acyltransferase 1 regulates morphology and function of P19C6 cell-derived neurons.2016

    • Author(s)
      Tabe, S., Hikiji, H., Ariyoshi, W., Hashidate-Yoshida, T., Shindou, H., Okinaga, T., Shimizu, T., Tominaga, K., and Nishihara, T.
    • Journal Title

      FASEB J.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Journal Article] Lysophosphatidylethanolamina acyltransfcrase/membrane-bound O-acyltransferase 1 regulates morphology and function of P19C6 cell-derived neurons.2016

    • Author(s)
      Tabe S, Hikiji H, Ariyoshi W, Hashidate-Yoshida T, Shindou H,Okinaga T, Shimizu T, Tominaga K,Nishihara T.
    • Journal Title

      FASEB. J

      Volume: 30 Issue: 7 Pages: 2591-2601

    • DOI

      10.1096/fj.201500097r

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05545, KAKENHI-PROJECT-26460380, KAKENHI-PROJECT-15K15696, KAKENHI-PROJECT-15K15746, KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-16K21651
  • [Journal Article] Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport.2015

    • Author(s)
      Hashidate-Yoshida T, Harayama T, Hishikawa D, Morimoto R, Hamano F, Tokuoka SM, Eto M, Tamura-Nakano M, Yanobu-Takanashi R, Mukumoto Y, Kiyonari H, Okamura T, Kita Y, Shindou H, Shimizu T.
    • Journal Title

      Elife

      Volume: Apr 21;4 Pages: 4-4

    • DOI

      10.7554/elife.06328

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860202, KAKENHI-PROJECT-26870879, KAKENHI-PROJECT-24229003
  • [Journal Article] Fever is mediated by conversion of endocannabinoid 2-arachidonoylglycerol to prostaglandin E<sub>2</sub>2015

    • Author(s)
      Yoshihiro Kita, Kenij Yoshida, Suzumi M. Tokuoka, Fumie Hamano, Maya Yamazaki, Kenji Sakimura, Masanobu Kano, Takao Shimizu
    • Journal Title

      PLoS One

      Volume: 10 Issue: 7 Pages: e0133663-e0133663

    • DOI

      10.1371/journal.pone.0133663

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08296, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24240048, KAKENHI-PROJECT-24229003, KAKENHI-PROJECT-25000015
  • [Journal Article] Essential Role of Lysophosphatidylcholine Acyltransferase 3 in the Induction of Macrophage Polarization in PMA-Treated U937 Cells2015

    • Author(s)
      Taniguchi K, Hikiji H, Okinaga T, Hashidate-Yoshida T, Shindou H, Ariyoshi W, Shimizu T, Tominaga K, Nishihara T
    • Journal Title

      J Cell Biochem

      Volume: 116 Issue: 12 Pages: 2840-2848

    • DOI

      10.1002/jcb.25230

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-26460380, KAKENHI-PROJECT-15K15746, KAKENHI-PROJECT-26870879, KAKENHI-PROJECT-24229003
  • [Journal Article] A comprehensive quantification method for eicosanoids and related compounds by using liquid chromatography/mass spectrometry with high speed continuous ionization polarity switching.2015

    • Author(s)
      Yamada, M., Kita, Y., Kohira, T., Yoshida, K., Hamano, F.,Tokuoka M, S., and Shimizu,T.
    • Journal Title

      J. Chrom. B.

      Volume: 995-996 Pages: 74-84

    • DOI

      10.1016/j.jchromb.2015.05.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Journal Article] Fatty acyl-chain remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport.

    • Author(s)
      Hashidate-Yoshida T., Harayama T., Hishikawa D., Morimoto R., Hamano F., Mitamura-Tokuoka S., Eto M., Tamura-Nakano M., Yanobu-Takanashi R., Mukumoto Y., Kiyonari H., Okamura T., Kita Y., Shindou H., and Shimizu T.
    • Journal Title

      eLife

      Volume: 21 Pages: 06328-06328

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460380
  • [Presentation] Increased arachidonic acid-containing phospholipids in the dorsal root ganglion contribute to the pathogenesis of neuropathic pain2023

    • Author(s)
      Shota Yamamoto, Tomomi Hashidate-Yoshida, Takao Shimizu, Hideo Shindou
    • Organizer
      Neuroscience 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06820
  • [Presentation] アラキドン酸含有リン脂質制御による中性脂肪の輸送調節2016

    • Author(s)
      吉田(橋立)智美
    • Organizer
      第17回 Atherosclerosis and Biolipid Conference
    • Place of Presentation
      ヒルトン東京お台場、東京
    • Year and Date
      2016-08-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] Roles for monoacylglycerol lipase in inflammation and metabolic syndrome2015

    • Author(s)
      北芳博、吉田憲司、徳岡涼美、浜野文三江、崎村建司、狩野方伸、清水孝雄
    • Organizer
      6ht International Conference on Phospholipase A2 and Lipid Mediators PLM2015
    • Place of Presentation
      新宿 京王プラザホテル東京
    • Year and Date
      2015-02-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] The role of lysophosphatidylcholine acyltransferase 3 (LPCAT3) modulating triacylglycerol transport2015

    • Author(s)
      Tomomi Hashidate-Yoshida, Takeshi Harayama, Daisuke Hishikawa, Ryo Morimoto, Fumie Hamano, Suzumi M. Tokuoka, Miki Eto, Yoshihiro Kita, Hideo Shindou, and Takao Shimizu
    • Organizer
      BMB2015
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-26870879
  • [Presentation] GC-MSを用いた二重標識水法によるエネルギー消費量評価法の改良2015

    • Author(s)
      浜野文三江、北芳博、吉田憲司、清水孝雄
    • Organizer
      第38回日本分子生物学会年会/第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド (兵庫県神戸市中央区港島中町6-11-1)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] Monoacylglycerol lipase knockout mice are resistant to high fat diet-induced obesity in an endocannabinoid system-independent manner2015

    • Author(s)
      吉田憲司 、北芳博、徳岡涼美、崎村建司、狩野方伸 、清水孝雄
    • Organizer
      6ht International Conference on Phospholipase A2 and Lipid Mediators PLM2015
    • Place of Presentation
      新宿 京王プラザホテル東京
    • Year and Date
      2015-02-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] The role of lysophosphatidylcholine acyltransferase 3 (LPCAT3) modulating triacylglycerol transport2015

    • Author(s)
      橋立(吉田)智美、原山武士、菱川大介、森本亮、浜野文三江、徳岡涼美、衛藤樹、北芳博、進藤英雄、清水孝雄
    • Organizer
      第38回日本分子生物学会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド (兵庫県神戸市中央区港島中町6-11-1)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] モノアシルグリセロールリパーゼによる脂質ホメオスタシスの制御2015

    • Author(s)
      北 芳博、吉田憲司、徳岡涼美、浜野文三江、崎村建司、狩野方伸、清水孝雄
    • Organizer
      第38回日本分子生物学会年会/第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド (兵庫県神戸市中央区港島中町6-11-1)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] リゾホスファチジルコリンアシル転移酵素3(LPCAT3)による トリアシルグリセロール輸送の調節機構2015

    • Author(s)
      橋立(吉田) 智美 、原山 武士 、菱川 大介、森本 亮、浜野 文三江、 徳岡 涼美、衛藤 樹、北 芳博、進藤 英雄、清水 孝雄
    • Organizer
      第57回日本脂質生化学会
    • Place of Presentation
      一橋大学 一橋講堂 (東京都千代田区一ツ橋2-1-2)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] リゾホスファチジルコリンアシル転移酵素3(LPCAT3)によるトリアシルグリセロール輸送の調節機構2015

    • Author(s)
      橋立(吉田)智美、原山武士、菱川大介、森本亮、浜野文三江、徳岡涼美、衛藤樹、北芳博、進藤英雄、清水孝雄
    • Organizer
      第57回日本脂質生化学会
    • Place of Presentation
      東京(一橋大学一橋講堂)
    • Year and Date
      2015-05-29
    • Data Source
      KAKENHI-PROJECT-26870879
  • [Presentation] Deficiency of monoacylglycerol lipase attenuates diet-induced obesity in an endocannabinoid system-independent manner2014

    • Author(s)
      Kenji Yoshida, Yoshihiro Kita, Suzumi Tokuoka, Kenji Sakimura, Masanobu Kano, Takao Shimizu
    • Organizer
      LIPID MAPS Annual Meeting 2014 Lipidomics Impact on Cell Biology, Inflammation and Metabolic Disease
    • Place of Presentation
      Scripps Seaside Forum of the University of California San Diego's Scripps Institution of Oceanography
    • Year and Date
      2014-05-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] モノアシルグリセロールリパーゼ欠損は高脂肪食負荷誘導性肥満を抑制する2014

    • Author(s)
      吉田 憲司, 北 芳博, 徳岡 涼美, 崎村 建司, 狩野 方伸, 清水 孝雄
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] Monoacylglycerol lipase mediates fever via hypothalamic prostaglandin E2 production2014

    • Author(s)
      Yoshihiro Kita, Kenji Yoshida, Suzumi M. Tokuoka, Fumie Hamano, Kenji Sakimura, Masanobu Kano,Takao Shimizu
    • Organizer
      LIPID MAPS Annual Meeting 2014
    • Place of Presentation
      Scripps Seaside Forum UCSD、La Jolla CA, USA
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] 発熱応答にはモノアシルグリセロールリパーゼ依存的なプロスタグランジンE2産生が必要である2014

    • Author(s)
      北芳博、吉田憲司、徳岡涼美、浜野文三江、山崎真弥、崎村建司、狩野方伸、清水孝雄
    • Organizer
      第87回 日本生化学会大会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] モノアシルグリセロールリパーゼ欠損は高脂肪食負荷による肥満を抑制する2014

    • Author(s)
      吉田 憲司、北 芳博、徳岡 涼美、崎村 建司、狩野 方伸、清水 孝雄
    • Organizer
      第56回 日本脂質生化学会
    • Place of Presentation
      近畿大学 東大阪キャンパス
    • Year and Date
      2014-06-06
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] Monoacylglycerol lipase mediates fever via hypothalamic prostaglandin E2 production2014

    • Author(s)
      Yoshihiro Kita, Kenji Yoshida, Suzumi M. Tokuoka, Fumie Hamano, Kenji Sakimura, Masanobu Kano, Takao Shimizu
    • Organizer
      LIPID MAPS Annual Meeting 2014 Lipidomics Impact on Cell Biology, Inflammation and Metabolic Disease
    • Place of Presentation
      Scripps Seaside Forum of the University of California San Diego's Scripps Institution of Oceanography
    • Year and Date
      2014-05-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24229003
  • [Presentation] Deficiency of monoacylglycerol lipase attenuates diet-induced obesity in an endocannabinoid system-independent manner2014

    • Author(s)
      Kenji Yoshida, Yoshihiro Kita, Suzumi Tokuoka, Kenji Sakimura, Masanobu Kano, Takao Shimizu
    • Organizer
      LIPID MAPS Annual Meeting 2014
    • Place of Presentation
      Scripps Seaside Forum UCSD、La Jolla CA, USA
    • Data Source
      KAKENHI-PROJECT-24229003
  • 1.  SHINDOU Hideo (10401027)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 2.  HISHIKAWA Daisuke (10569966)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  HARAYAMA Takeshi (50610218)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  Shimizu Takao (80127092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 5.  NAKAMURA Motonao (40431762)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KITA Yoshihiro (20401028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 7.  TOKUOKA Suzumi (60511376)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 8.  HISHIKAWA Yoshiko (60436574)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TARUI Megumi (40727749)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  山本 将大 (50825693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  YANAGIDA Keisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  VALENTINE William
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAKAHASHI Yoshikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAGATA Katsuyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Eto Miki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  MORIMOTO Ryo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  AMEMIYA Ami
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TODORIKI Naruha
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ITO Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  飯塚 佳子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  沖永 敏則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  引地 尚子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  西原 達次
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  冨永 和宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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