Hara Ai 原愛 (野上愛)

… Alternative Names

野上愛

Nogami-Hara Ai 原愛

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Researcher Number	30614953
Other IDs
Affiliation (Current)	2025: 就実大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2024: 就実大学, 薬学部, 講師 2017 – 2019: 就実大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator 0904:Internal medicine of the bio-information integration and related fields / Applied pharmacology
Keywords	Principal Investigator 小児白血病 / 薬物アレルギー / L-アスパラギナーゼ / 小児がん / モデル動物 / L-asparaginese / 中和抗体 / オマリズマブ / 急性リンパ性白血病 / アレルギー / L-asparaginase

L-アスパラギナーゼに対するサイトカインプロファイル解析と特異的抗体の検出Principal Investigator
- Principal Investigator
  
  原愛 (野上愛)
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0904:Internal medicine of the bio-information integration and related fields
- Research Institution
  Shujitsu University
Investigation of pathophysiology of L-asparaginase allergy and development of novel diagnostic and therapeutic methodsPrincipal Investigator
- Principal Investigator
  
  Nogami-Hara Ai
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Shujitsu University

All 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] L-アスパラギナーゼアレルギーの病態解明と臨床応用を志向した新規in vitro検査法の開発2019
- Author(s)
  原（野上）愛、嶋田明、見尾光庸
- Journal Title
  
  アレルギーの臨床
  
  Volume: 39 (5) Pages: 49-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15762
[Journal Article] Extract of Yokukansan improves anxiety-like behavior and increases serum brain-derived neurotrophic factor in rats with cerebral ischemia combined with amyloid-β42 peptide.2019
- Author(s)
  Nogami-Hara A, Kubota K, Takasaki K, Watanabe T, Egashira N, Iba H, Fujikawa R, Katsurabayashi S, Hatip FB, Name Date Signature, Hatip-Al-Khatib I, Iwasaki K.
- Journal Title
  
  J Tradit Chin Med
  
  Volume: 39 (1) Pages: 50-58
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15762
[Journal Article] The Japanese Angelica acutiloba root and yokukansan increase hippocampal acetylcholine level, prevent apoptosis and improve memory in a rat model of repeated cerebral ischemia.2018
- Author(s)
  Nogami-Hara A, Nagao M, Takasaki K, Egashira N, Fujikawa R, Kubota K, Watanabe T, Katsurabayashi S, Hatip FB, Hatip-Al-Khatib I, Iwasaki K.
- Journal Title
  
  J Ethnopharmacol.
  
  Volume: 214 Pages: 190-196
- DOI
  10.1016/j.jep.2017.12.025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08315, KAKENHI-PROJECT-17K15762
[Journal Article] L-Asparaginase-induced allergy in mice in vivo sensitization and in vitro activation of RBL-2H3 cells2017
- Author(s)
  Mio Mitsunobu，Nogami-Hara Ai，Yabuki Kazue，Suwaki Kawori，Handa Ai, Mitsuhata Chie, Kajiyama Koji and Shimada Akira
- Journal Title
  
  Inflammation Research
  
  Volume: 66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] L-アスパラギナーゼアレルギーに対するシクロホスファミド併用の影響と抗IgE抗体の効果2020
- Author(s)
  原（野上）愛，堀優太，須々木健太郎，光畑知恵，梶山光司、嶋田明，見尾光庸
- Organizer
  第22回日本ヒスタミン学会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] L-アスパラギナーゼ誘発アレルギーの併用薬によるリスク管理2019
- Author(s)
  原（野上）愛
- Organizer
  第24回公益財団法人がんの子どもを守る会公開シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] マウスと培養肥満細胞を用いたＬ-アスパラギナーゼ誘発アレルギーの評価2019
- Author(s)
  原（野上）愛，半田　愛，光畑知恵，梶山光司，神田翔磨，須々木健太郎，嶋田　明，見尾光庸
- Organizer
  第58回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] Allergic activation of RBL-2H3 mast cells with L-Asparaginase and its inhibition by anti-IgE antibody2019
- Author(s)
  Ai Nogami-Hara, Ai Handa, Chie Mitsuhata, Koji Kajiyama, Shoma Kanda, Kentaro Susuki, Akira Shimada, Mitsunobu Mio
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] L-アスパラギナーゼアレルギーに対するシクロホスファミド併用の影響と抗IgE抗体の効果2019
- Author(s)
  原（野上）愛，堀優太，須々木健太郎，光畑知恵，梶山光司，嶋田明，見尾光庸
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] Influence of cyclophosphamide on L-Asparaginase-induced allergy in mice and RBL-2H3 cells.2019
- Author(s)
  Nogami-Hara A, Hori Y, Mitsuhata C, Kajiyama K, Susuki K, Shimada A, Mio M
- Organizer
  第61回日本小児血液・がん学会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] 抗てんかん薬使用による葉酸・カルニチン低下に対する指導内容適正化の検討2017
- Author(s)
  吉井圭佑、原（野上）愛、梶俊策、見尾光庸、杉山哲大
- Organizer
  第27回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] Allergic activation of RBL-2H3 mast cells with L-Asparaginase and its inhibition by anti-IgE antibody2017
- Author(s)
  Nogami-Hara Ai, Handa Ai, Mitsuhata Chie, Kajiyama Koji, Kanda Shoma, Susuki Kentaro, Shimada Akira and Mio Mitsunobu
- Organizer
  第59回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] L-asparaginase-induced allergy in mice: in vivo sensitization and in vitro activation of RBL-2H3 cells L-Asparaginase-induced allergy in mice: effects of concomitant drugs and anti-IgE antibody2017
- Author(s)
  Mio Mitsunobu，Nogami-Hara Ai，Yabuki Kazue，Suwaki Kawori，Handa Ai, Mitsuhata Chie, Kajiyama Koji and Shimada Akira
- Organizer
  The First Joint Meeting of the EuropeanHistamine Research Society and JapaneseHistamine Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] L-アスパラギナーゼアレルギーによる RBL-2H3 肥満細胞活性化と抗 IgE 抗体の抑制作用2017
- Author(s)
  見尾光庸、原（野上）愛、半田愛、光畑知恵、梶山光司、神田翔磨、須々木健太郎、嶋田明
- Organizer
  第21回日本ヒスタミン学会
- Data Source
  KAKENHI-PROJECT-17K15762
[Presentation] Allergic activation of RBL-2H3 mast cells with L-Asparaginase and its inhibition by anti-IgE antibody2017
- Author(s)
  Nogami-Hara Ai, Mio Mitsunobu and Shimada Akira
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15762

1. Katsurabayashi Shutaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. Iwasaki Katsunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 窪田香織

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hara Ai 原 愛 (野上 愛)

野上愛

Nogami-Hara Ai 原 愛

Research Projects

Research Products

Co-Researchers

L-アスパラギナーゼに対するサイトカインプロファイル解析と特異的抗体の検出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of pathophysiology of L-asparaginase allergy and development of novel diagnostic and therapeutic methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] L-アスパラギナーゼアレルギーの病態解明と臨床応用を志向した新規in vitro検査法の開発2019

Author(s)

Journal Title

Data Source

[Journal Article] Extract of Yokukansan improves anxiety-like behavior and increases serum brain-derived neurotrophic factor in rats with cerebral ischemia combined with amyloid-β42 peptide.2019

Author(s)

Journal Title

Data Source

[Journal Article] The Japanese Angelica acutiloba root and yokukansan increase hippocampal acetylcholine level, prevent apoptosis and improve memory in a rat model of repeated cerebral ischemia.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] L-Asparaginase-induced allergy in mice in vivo sensitization and in vitro activation of RBL-2H3 cells2017

Author(s)

Journal Title

Data Source

[Presentation] L-アスパラギナーゼアレルギーに対するシクロホスファミド併用の影響と抗IgE抗体の効果2020

Author(s)

Organizer

Data Source

[Presentation] L-アスパラギナーゼ誘発アレルギーの併用薬によるリスク管理2019

Author(s)

Organizer

Data Source

[Presentation] マウスと培養肥満細胞を用いたＬ-アスパラギナーゼ誘発アレルギーの評価2019

Author(s)

Organizer

Data Source

[Presentation] Allergic activation of RBL-2H3 mast cells with L-Asparaginase and its inhibition by anti-IgE antibody2019

Author(s)

Organizer

Data Source

[Presentation] L-アスパラギナーゼアレルギーに対するシクロホスファミド併用の影響と抗IgE抗体の効果2019

Author(s)

Organizer

Data Source

[Presentation] Influence of cyclophosphamide on L-Asparaginase-induced allergy in mice and RBL-2H3 cells.2019

Author(s)

Organizer

Data Source

[Presentation] 抗てんかん薬使用による葉酸・カルニチン低下に対する指導内容適正化の検討2017

Author(s)

Organizer

Data Source

[Presentation] Allergic activation of RBL-2H3 mast cells with L-Asparaginase and its inhibition by anti-IgE antibody2017

Author(s)

Organizer

Data Source

[Presentation] L-asparaginase-induced allergy in mice: in vivo sensitization and in vitro activation of RBL-2H3 cells L-Asparaginase-induced allergy in mice: effects of concomitant drugs and anti-IgE antibody2017

Author(s)

Organizer

Data Source

[Presentation] L-アスパラギナーゼアレルギーによる RBL-2H3 肥満細胞活性化と抗 IgE 抗体の抑制作用2017

Author(s)

Organizer

Data Source

[Presentation] Allergic activation of RBL-2H3 mast cells with L-Asparaginase and its inhibition by anti-IgE antibody2017

Author(s)

Organizer

Data Source

Hara Ai 原愛 (野上愛)

Nogami-Hara Ai 原愛