Aoki Kazunari 青木一成

Researcher Number	30618020
Other IDs
Affiliation (Current)	2025: 京都大学, 医生物学研究所, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 京都大学, 医生物学研究所, 助教 2021: 京都大学, ウイルス・再生医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 52040:Radiological sciences-related / Medium-sized Section 50:Oncology and related fields / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator CRISPR / T-ALL / 転写因子 / ニッシェ / 造血幹細胞 / 転写制御 / RUNX1 / クロマチン / ARID1A / SMARCA4 / cBAF / CXCR4 / CXCL12 … More Except Principal Investigator … More alfa-ray / theranostics / CRISPR / 合成致死 / 造血器腫瘍 / SWI/SNF / Cre / 分子標的 / 増殖必須因子 / 多発性骨髄腫 / in vivo CRISPRスクリーニング / in vivo model / Leukemia / Genetic screening / MM / T-ALL / スクリーニング / Flp / ゲノム編集 / in vivoモデル / 白血病 / 遺伝学的スクリーニング / CRISPR-Cas9 Less

SWI/SNF合成致死遺伝子による造血器腫瘍新規治療戦略の確立
- Principal Investigator
  
  遊佐宏介
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyoto University
α線を用いたRadiotheranosticsに対する治療抵抗性の病態解明
- Principal Investigator
  
  子安翔
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
転写因子を標的とした新規T-ALL治療戦略の開発Principal Investigator
- Principal Investigator
  
  青木一成
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Comprehensive exploration of intracellular factors essential for HSC regulation via the CXCL12-CXCR4 axisPrincipal Investigator
- Principal Investigator
  
  Aoki Kazunari
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
in vivo CRISPRスクリーニングの技術確立と生体内細胞増殖機構の解析
- Principal Investigator
  
  遊佐宏介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto University

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ueda Atsushi、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Journal Title
  
  Blood
  
  Volume: 143 Issue: 7 Pages: 604-618
- DOI
  10.1182/blood.2023020857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-21K08393, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-23K24298
[Journal Article] Significance of Omitting Day 11 Mini-Dose Methotrexate for GVHD Prophylaxis After Unrelated Bone Marrow Transplantation2023
- Author(s)
  Nakamura Naokazu、Wada Fumiya、Kondo Tadakazu、Aoki Kazunari、Arai Yasuyuki、Mizumoto Chisaki、Kanda Junya、Kitawaki Toshio、Yamashita Kouhei、Takaori-Kondo Akifumi
- Journal Title
  
  Transplantation and Cellular Therapy
  
  Volume: 29 Issue: 2 Pages: 119.e1-119.e7
- DOI
  10.1016/j.jtct.2022.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08393
[Journal Article] Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells2022
- Author(s)
  Omatsu Yoshiki、Aiba Shota、Maeta Tomonori、Higaki Kei、Aoki Kazunari、Watanabe Hitomi、Kondoh Gen、Nishimura Riko、Takeda Shu、Chung Ung-il、Nagasawa Takashi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 2654-2654
- DOI
  10.1038/s41467-022-30266-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08393, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023
- Author(s)
  Aoki K, Hyuga M, Tarumoto Y, Nishibuchi G, Ochi Y, Sugino S, Mikami T, Kobushi H, Kato I, Akahane K, Inukai T, Takaori-Kondo A, Takita J, Ogawa S, Yusa K.
- Organizer
  日本血液学会国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04959
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia.2023
- Author(s)
  Aoki K, Hyuga M, Tarumoto Y, Nishibuchi G, Ochi Y, Sugino S, Mikami T, Kobushi H, Kato I, Akahane K, Inukai T, Takaori-Kondo A, Takita J, Ogawa S, Yusa K.
- Organizer
  日本がん学会学術総会
- Data Source
  KAKENHI-PROJECT-21H04959
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Organizer
  The 82th Annual Meeting of the JCA
- Data Source
  KAKENHI-PROJECT-21K08393
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Organizer
  The 13th JSH International Symposium in Tsukuba
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08393

1. 遊佐宏介 (00813180)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 子安翔 (80781913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 志水陽一 (90634212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 渡部直史 (90648932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 滝田順子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Aoki Kazunari 青木 一成

Research Projects

Research Products

Co-Researchers

SWI/SNF合成致死遺伝子による造血器腫瘍新規治療戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

α線を用いたRadiotheranosticsに対する治療抵抗性の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写因子を標的とした新規T-ALL治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive exploration of intracellular factors essential for HSC regulation via the CXCL12-CXCR4 axisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

in vivo CRISPRスクリーニングの技術確立と生体内細胞増殖機構の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of Omitting Day 11 Mini-Dose Methotrexate for GVHD Prophylaxis After Unrelated Bone Marrow Transplantation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023

Author(s)

Organizer

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia.2023

Author(s)

Organizer

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023

Author(s)

Organizer

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023

Author(s)

Organizer

Data Source

Aoki Kazunari 青木一成