Aoki Kazunari 青木一成

Researcher Number	30618020
Other IDs	https://orcid.org/0000-0003-2172-2195
Affiliation (Current)	2026: 京都大学, 医生物学研究所, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 京都大学, 医生物学研究所, 助教 2021: 京都大学, ウイルス・再生医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 52040:Radiological sciences-related / Medium-sized Section 50:Oncology and related fields / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator CRISPR / T-ALL / 転写因子 / ニッシェ / 造血幹細胞 / 転写制御 / RUNX1 / クロマチン / ARID1A / SMARCA4 / cBAF / CXCR4 / CXCL12 … More Except Principal Investigator … More SWI/SNF / CRISPR / alfa-ray / theranostics / 合成致死 / 造血器腫瘍 / Cre / 分子標的 / 増殖必須因子 / 多発性骨髄腫 / in vivo CRISPRスクリーニング / in vivo model / Leukemia / Genetic screening / in vivoモデル / 白血病 / 遺伝学的スクリーニング / MM / Flp / ゲノム編集 / CRISPR-Cas9 / T-ALL / スクリーニング Less

SWI/SNF合成致死遺伝子による造血器腫瘍新規治療戦略の確立
- Principal Investigator
  
  遊佐宏介
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyoto University
α線を用いたRadiotheranosticsに対する治療抵抗性の病態解明
- Principal Investigator
  
  子安翔
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
転写因子を標的とした新規T-ALL治療戦略の開発Principal Investigator
- Principal Investigator
  
  青木一成
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Comprehensive exploration of intracellular factors essential for HSC regulation via the CXCL12-CXCR4 axisPrincipal Investigator
- Principal Investigator
  
  Aoki Kazunari
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Development of in vivo CRISPR screening technology and analysis of cell proliferation
- Principal Investigator
  
  Yusa Kosuke
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto University

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ueda Atsushi、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Journal Title
  
  Blood
  
  Volume: 143 Issue: 7 Pages: 604-618
- DOI
  10.1182/blood.2023020857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-21K08393, KAKENHI-PROJECT-22K16320, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-23K24298
[Journal Article] Significance of Omitting Day 11 Mini-Dose Methotrexate for GVHD Prophylaxis After Unrelated Bone Marrow Transplantation2023
- Author(s)
  Nakamura Naokazu、Wada Fumiya、Kondo Tadakazu、Aoki Kazunari、Arai Yasuyuki、Mizumoto Chisaki、Kanda Junya、Kitawaki Toshio、Yamashita Kouhei、Takaori-Kondo Akifumi
- Journal Title
  
  Transplantation and Cellular Therapy
  
  Volume: 29 Issue: 2 Pages: 119.e1-119.e7
- DOI
  10.1016/j.jtct.2022.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08393
[Journal Article] Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells2022
- Author(s)
  Omatsu Yoshiki、Aiba Shota、Maeta Tomonori、Higaki Kei、Aoki Kazunari、Watanabe Hitomi、Kondoh Gen、Nishimura Riko、Takeda Shu、Chung Ung-il、Nagasawa Takashi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 2654-2654
- DOI
  10.1038/s41467-022-30266-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08393, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023
- Author(s)
  Aoki K, Hyuga M, Tarumoto Y, Nishibuchi G, Ochi Y, Sugino S, Mikami T, Kobushi H, Kato I, Akahane K, Inukai T, Takaori-Kondo A, Takita J, Ogawa S, Yusa K.
- Organizer
  日本血液学会国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04959
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia.2023
- Author(s)
  Aoki K, Hyuga M, Tarumoto Y, Nishibuchi G, Ochi Y, Sugino S, Mikami T, Kobushi H, Kato I, Akahane K, Inukai T, Takaori-Kondo A, Takita J, Ogawa S, Yusa K.
- Organizer
  日本がん学会学術総会
- Data Source
  KAKENHI-PROJECT-21H04959
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Organizer
  The 82th Annual Meeting of the JCA
- Data Source
  KAKENHI-PROJECT-21K08393
[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023
- Author(s)
  Aoki Kazunari、Hyuga Mizuki、Tarumoto Yusuke、Nishibuchi Gohei、Ochi Yotaro、Sugino Seiichi、Mikami Takashi、Kobushi Hirokazu、Kato Itaru、Akahane Koshi、Inukai Takeshi、Takaori-Kondo Akifumi、Takita Junko、Ogawa Seishi、Yusa Kosuke
- Organizer
  The 13th JSH International Symposium in Tsukuba
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08393

1. Yusa Kosuke (00813180)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 子安翔 (80781913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 志水陽一 (90634212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 渡部直史 (90648932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 滝田順子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Aoki Kazunari 青木 一成

Research Projects

Research Products

Co-Researchers

SWI/SNF合成致死遺伝子による造血器腫瘍新規治療戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

α線を用いたRadiotheranosticsに対する治療抵抗性の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写因子を標的とした新規T-ALL治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive exploration of intracellular factors essential for HSC regulation via the CXCL12-CXCR4 axisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of in vivo CRISPR screening technology and analysis of cell proliferation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of Omitting Day 11 Mini-Dose Methotrexate for GVHD Prophylaxis After Unrelated Bone Marrow Transplantation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023

Author(s)

Organizer

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia.2023

Author(s)

Organizer

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023

Author(s)

Organizer

Data Source

[Presentation] Canonical BAF complex is essential for the RUNX1-driven oncogenic transcriptional program in human T-cell acute lymphoblastic leukemia2023

Author(s)

Organizer

Data Source

Aoki Kazunari 青木一成