Kawashiri Takehiro 川尻雄大

… Alternative Names

川尻雄大カワシリタケヒロ

KAWASHIRI Takehiro 川尻雄大

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Researcher Number	30621685
Other IDs
Affiliation (Current)	2022: 九州大学, 薬学研究院, 助教
Affiliation (based on the past Project Information) *help	2020 – 2021: 九州大学, 薬学研究院, 助教 2016 – 2017: 九州大学, 薬学研究院, 助教 2013 – 2014: 九州大学, 大学病院, その他
Review Section/Research Field	Principal Investigator Applied pharmacology / Pain science / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 58010:Medical management and medical sociology-related
Keywords	Principal Investigator オキサリプラチン / 末梢神経障害 / 抗がん薬 / 副作用（有害事象） / グルタミン酸 / グルタミン酸トランスポーター / 脊髄内マイクロダイアリシス法 / しびれ / 抗がん剤 / 大腸がん … More / パクリタキセル / シスプラチン / ボルテゾミブ / フマル酸ジメチル / 手足症候群 / カペシタビン / ドラッグ・リポジショニング / がん化学療法 / 支持療法 … More Except Principal Investigator 末梢神経障害 / 抗がん薬 / 生体膜リン脂質 / がん化学療法 / ドラッグリポジショニング / 節薬バッグ運動 / 残薬 / 麻薬 / 廃棄 / 薬剤師職能 / 節薬バッグ / 医療用麻薬 / 医療費削減 Less

生体膜リン脂質に着目した抗がん薬誘発末梢神経障害予防/治療薬の開発
- Principal Investigator
  
  江頭伸昭
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyushu University
ドラッグ・リポジショニングを活用した大腸がん化学療法に伴う有害事象の回避法の確立Principal Investigator
- Principal Investigator
  
  川尻雄大
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyushu University
薬剤師の職能としての残薬調査および調整に関する取り組みについての解析
- Principal Investigator
  
  島添隆雄
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Kyushu University
Studies on mechanisms and prevention of chemotherapy-induced peripheral neuropathyPrincipal Investigator
- Principal Investigator
  
  Kawashiri Takehiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyushu University
Reseach for new therapeutic targets of oxaliplatin-induced peripheral neuropathyPrincipal Investigator
- Principal Investigator
  
  KAWASHIRI Takehiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
  Pain science
- Research Institution
  Kyushu University

All 2021 2020 2017 2016 2014 2013 Other

All Journal Article Presentation

[Journal Article] Analgesic Effects of Sokeikakketsuto on Chemotherapy-Induced Mechanical Allodynia and Cold Hyperalgesia in Rats2021
- Author(s)
  Nakamura Hiroko、Kawashiri Takehiro、Kobayashi Daisuke、Uchida Mayako、Egashira Nobuaki、Shimazoe Takao
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 44 Issue: 2 Pages: 271-274
- DOI
  10.1248/bpb.b20-00620
- NAID
  130007979607
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-20K07198
[Journal Article] Therapeutic agents for oxaliplatin-induced peripheral neuropathy; experimental and clinical evidence.2021
- Author(s)
  Kawashiri Takehiro、Mine Keisuke、Kobayashi Daisuke、Inoue Mizuki、Ushio Soichiro、Uchida Mayako、Egashira Nobuaki、Shimazoe Takao
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22 Pages: 1393-1393
- DOI
  10.3390/ijms22031393
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-20K07198, KAKENHI-PROJECT-19K16429
[Journal Article] Oral administration of Cystine and Theanine ameliorates oxaliplatin-induced chronic peripheral neuropathy in rodents2020
- Author(s)
  Kawashiri Takehiro、Kobayashi Daisuke、Egashira Nobuaki、Tsuchiya Takashi、Shimazoe Takao
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 12665-12665
- DOI
  10.1038/s41598-020-69674-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-20K07198
[Journal Article] Excessive spinal glutamate transmission is involved in oxaliplatin-induced mechanical allodynia: a possibility for riluzole as a prophylactic drug.2017
- Author(s)
  Yamamoto Shota、Ushio Soichiro、Egashira Nobuaki、Kawashiri Takehiro、Mitsuyasu Shohei、Higuchi Hitomi、Ozawa Nana、Masuguchi Ken、Ono Yuko、Masuda Satohiro
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Pages: 9661-9661
- DOI
  10.1038/s41598-017-08891-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08953, KAKENHI-PROJECT-15H04666, KAKENHI-PROJECT-16K19184
[Journal Article] Polaprezinc reduces paclitaxel-induced peripheral neuropathy in rats without affecting anti-tumor activity.2016
- Author(s)
  Tsutsumi K, Kaname T, Shiraishi H, Kawashiri T, Egashira N.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 131 Pages: 146-149
- DOI
  10.1016/j.jphs.2016.04.019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K19184
[Journal Article] Neurotropin® relieves oxaliplatin-induced neuropathy via Gi protein-coupled receptors in the monoaminergic descending pain inhibitory system.2014
- Author(s)
  Masuguchi K, Watanabe H, Kawashiri T, Ushio S, Ozawa N, Morita H, Oishi R, Egashira N
- Journal Title
  
  Life Sciences
  
  Volume: 98巻 Pages: 49-54
- DOI
  10.1016/j.lfs.2013.12.229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460335, KAKENHI-PROJECT-25870496
[Journal Article] Oxaliplatin induces hypomyelination and reduced neuregulin 1 expression in the rat sciatic nerve.2014
- Author(s)
  Tsutsumi K, Yamashita Y, Ushio S, Kawashiri T, Kaname T, Fujita S, Oishi R, Egashira N
- Journal Title
  
  Neuroscience Research
  
  Volume: 80巻 Pages: 86-90
- DOI
  10.1016/j.neures.2014.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460335, KAKENHI-PROJECT-25870496
[Journal Article] Basic evidence for efficacy of Goshajinkigan on oxaliplatin-induced neuropathy.2014
- Author(s)
  Ushio S, Kawashiri T, Egashira N.
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 143 Pages: 126-130
- NAID
  130003391434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870496
[Journal Article] Substance P in antitumor drug-induced adverse reactions.2013
- Author(s)
  Yano T, Kawashiri T, Egashira N, Oishi R.
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 142 Pages: 255-255
- NAID
  130003382531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] がん化学療法誘発末梢神経障害に対するDPP-4阻害薬アログリプチンの抑制作用に関する基礎的検討2020
- Author(s)
  川尻雄大, 重松奈央, 清水栞, 峯圭佑, 廣本詩織, 小林大介, 江頭伸昭, 島添隆雄
- Organizer
  第41回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07198
[Presentation] カペシタビン誘発手足症候群の動物モデルの確立と抑制薬の探索2020
- Author(s)
  廣本詩織, 川尻雄大, 山中捺未, 小林大介, 島添隆雄
- Organizer
  第41回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07198
[Presentation] オキサリプラチン誘発末梢神経障害に対するシスチン・テアニン経口投与の有用性に関する基礎的検討2020
- Author(s)
  川尻雄大、小林大介、江頭伸昭、島添隆雄
- Organizer
  第30回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07198
[Presentation] 神経線維の変性を標的とした抗がん剤誘発末梢神経障害の対応策確立を目指した研究2017
- Author(s)
  宮城杏奈, 川尻雄大, 清水栞, 重松奈央, 小林大介, 島添隆雄
- Organizer
  第28回霧島神経薬理フォーラム
- Data Source
  KAKENHI-PROJECT-16K19184
[Presentation] オキサリプラチン誘発機械的アロディニアにおける脊髄内グルタミン酸の関与2014
- Author(s)
  牛尾聡一郎、光安正平、小澤奈々、小野佑子、川尻雄大、増田智先、大石了三、江頭伸昭
- Organizer
  第87回　日本薬理学会年会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] オキサリプラチン誘発末梢神経障害に対するエキセナチドの効果2014
- Author(s)
  藤田隼輔、牛尾聡一郎、益口賢、小澤奈々、小野佑子、馬場美咲、川尻雄大、増田智先、大石了三
- Organizer
  第87回　日本薬理学会年会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] オキサリプラチンによる神経障害ならびに抗腫瘍効果に対する3-Aminobenzamideの作用2013
- Author(s)
  藤田隼輔、牛尾聡一郎、川尻雄大、森田春香、馬場美咲、江頭伸昭
- Organizer
  第66回　日本薬理学会西南部会
- Place of Presentation
  福岡大学（福岡市）
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] オキサリプラチン誘発機械的アロディニアにおけるグルタミン酸神経系の関与2013
- Author(s)
  光安正平、牛尾聡一郎、川尻雄大、大石了三、江頭伸昭
- Organizer
  第66回　日本薬理学会西南部会
- Place of Presentation
  福岡大学（福岡市）
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] オキサリプラチン、パクリタキセルおよびボルテゾミブによる末梢神経障害の発現機序の違い
- Author(s)
  川尻雄大、堤国章、山本将大、牛尾聡一郎、江頭伸昭、増田智先
- Organizer
  第 8 回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本大学（熊本市）
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] パクリタキセル誘発末梢神経障害における炎症反応の関与
- Author(s)
  堤国章、要幸典、川尻雄大、白石遥、江頭伸昭、増田智先
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] ボルテゾミブ誘発末梢神経障害に対する牛車腎気丸の効果
- Author(s)
  樋口瞳、山本将大、牛尾聡一郎、川尻雄大、江頭伸昭、増田智先
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] パクリタキセル誘発末梢神経障害の発現要因解析
- Author(s)
  要幸典、川尻雄大、江頭伸昭、増田智先
- Organizer
  第 31 回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡市）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] Prophylactic effect of calcium channel blockers against oxaliplatin-induced acute peripheral neuropathy
- Author(s)
  Kawashiri T, Tsutsumi K, Ushio S, Egashira N, Masuda S.
- Organizer
  Experimental Biology 2014
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-25870496
[Presentation] Association between decreased expression of GLT-1 derived spinal glutamate accumulation and oxaliplatin-induced mechanical allodynia
- Author(s)
  Ushio S, Mitsuyasu S, Masuguchi K, Ozawa N, Ono Y, Kawashiri T, Egashira N, Masuda S.
- Organizer
  Experimental Biology 2014
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-25870496

1. 小林大介 (00403973)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 江頭伸昭 (80352269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 山本将大 (50825693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 島添隆雄 (10202110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMAMOTO Nanae

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. TSUTSUMI Kuniaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 増田智先

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 内田まやこ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawashiri Takehiro 川尻 雄大

川尻 雄大 カワシリ タケヒロ

KAWASHIRI Takehiro 川尻 雄大

Research Projects

Research Products

Co-Researchers

生体膜リン脂質に着目した抗がん薬誘発末梢神経障害予防/治療薬の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ドラッグ・リポジショニングを活用した大腸がん化学療法に伴う有害事象の回避法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

薬剤師の職能としての残薬調査および調整に関する取り組みについての解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on mechanisms and prevention of chemotherapy-induced peripheral neuropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Reseach for new therapeutic targets of oxaliplatin-induced peripheral neuropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analgesic Effects of Sokeikakketsuto on Chemotherapy-Induced Mechanical Allodynia and Cold Hyperalgesia in Rats2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Therapeutic agents for oxaliplatin-induced peripheral neuropathy; experimental and clinical evidence.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral administration of Cystine and Theanine ameliorates oxaliplatin-induced chronic peripheral neuropathy in rodents2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Excessive spinal glutamate transmission is involved in oxaliplatin-induced mechanical allodynia: a possibility for riluzole as a prophylactic drug.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polaprezinc reduces paclitaxel-induced peripheral neuropathy in rats without affecting anti-tumor activity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurotropin® relieves oxaliplatin-induced neuropathy via Gi protein-coupled receptors in the monoaminergic descending pain inhibitory system.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oxaliplatin induces hypomyelination and reduced neuregulin 1 expression in the rat sciatic nerve.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Basic evidence for efficacy of Goshajinkigan on oxaliplatin-induced neuropathy.2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Substance P in antitumor drug-induced adverse reactions.2013

Kawashiri Takehiro 川尻雄大

川尻雄大カワシリタケヒロ

KAWASHIRI Takehiro 川尻雄大