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Kageyama Shun  蔭山 俊

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KAGEYAMA Shun  蔭山 俊

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Researcher Number 30624225
Other IDs
Affiliation (Current) 2022: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2019 – 2020: 順天堂大学, 医学部, 助教
2018: 新潟大学, 医歯学系, 助教
2014 – 2015: 新潟大学, 医歯学系, 助教
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Basic Section 48040:Medical biochemistry-related / Basic Section 43030:Functional biochemistry-related
Keywords
Principal Investigator
オートファジー / p62 / プロテアソーム / ユビキチン / 凝集体 / Sqstm1/p62 / Nrf2 / Keap1 / ユビキチン-プロテアソームシステム / Atg7 … More / psmc1 / Sqstm1-GFP / Alfy / 小胞輸送経路 / 自閉症スペクトラム症 / 神経突起 / Rab / メンブレントラフィック / 選択的オートファジー / GABARAP / アダプタータンパク質 / 小胞輸送 / 液-液相分離 / 液滴 / LC3/GABARAP / Keap1-Nrf2経路 / p62/SQSTM1 / 相分離 Less
  • Research Projects

    (3 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (37 People)
  •  選択的オートファジー基質p62/SQSTM1液滴の分子病態の解析Principal Investigator

    • Principal Investigator
      蔭山 俊
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Juntendo University
  •  Functional analysis of Alfy, a selective autophagy related molecule involved in brain formationPrincipal Investigator

    • Principal Investigator
      Kageyama Shun
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Juntendo University
      Niigata University
  •  Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathwayPrincipal Investigator

    • Principal Investigator
      KAGEYAMA Shun
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Niigata University

All 2021 2020 2019 2018 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2021

    • Author(s)
      Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M.
    • Journal Title

      Nat Commun.

      Volume: 12 Pages: 1-16

    • DOI

      10.1038/s41467-020-20185-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07276, KAKENHI-PROJECT-20K06549, KAKENHI-PROJECT-20K06644, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-20H03415
  • [Journal Article] p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control2021

    • Author(s)
      Eskelinen Eeva-Liisa、Kageyama Shun、Komatsu Masaaki
    • Journal Title

      Molecular & Cellular Oncology

      Volume: 8 Pages: 1890990-1890990

    • DOI

      10.1080/23723556.2021.1890990

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06549
  • [Journal Article] NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system.2020

    • Author(s)
      Sanchez-Martin P, Sou YS, Kageyama S, Koike M, Waguri S, *Komatsu M.
    • Journal Title

      EMBO Rep.

      Volume: 21

    • DOI

      10.15252/embr.201948902

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18F18099, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-18K15043, KAKENHI-PROJECT-16H06276
  • [Journal Article] Hyperosmotic Stress Induces Unconventional Autophagy Independent of the U1K1 Complex.2019

    • Author(s)
      Tamura N, Kageyama S, Komatsu M, Waguri S.
    • Journal Title

      Mol Cell Biol.

      Volume: 39

    • DOI

      10.1128/mcb.00024-19

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-18K15043, KAKENHI-PROJECT-16H06276
  • [Journal Article] Deletion of exons encoding carboxypeptidase domain of Nnal results in Purkinje cell degeneration (pcd) phenotype.2018

    • Author(s)
      Zhou L, Hossain MI, Yamazaki M, Abe M, Natsume R, Konno K, Kageyama S, Komatsu M, Watanabe M, Sakimura K, Takebayashi H.
    • Journal Title

      J Neurochem.

      Volume: 147 Pages: 557-572

    • DOI

      10.1111/jnc.14591

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-18K06813, KAKENHI-PROJECT-18K15043, KAKENHI-WRAPUP-18H05199, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-17K19444, KAKENHI-PLANNED-25117007, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02592
  • [Journal Article] Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease.2016

    • Author(s)
      Kuwahara S, Hosojima M, Kaneko R, Aoki H, Nakano D, Sasagawa T, Kabasawa H, Kaseda R, Yasukawa R, Ishikawa T, Suzuki A, Sato H, Kageyama S, Tanaka T, Kitamura N, Narita I, Komatsu M, Nishiyama A, Saito A
    • Journal Title

      Journal of the American Society of Nephrology.

      Volume: in press Pages: 1996-2008

    • DOI

      10.1681/asn.2015020190

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670429, KAKENHI-PROJECT-26860224, KAKENHI-PROJECT-26293201, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-26461216, KAKENHI-PROJECT-15K11309
  • [Journal Article] オートファジーの誘導2015

    • Author(s)
      蔭山俊
    • Journal Title

      THE LUNG perspectives

      Volume: 23 Pages: 47-51

    • Data Source
      KAKENHI-PROJECT-26860224
  • [Journal Article] Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells2015

    • Author(s)
      Atsushi Eino, Shun Kageyama, Takefumi Uemura, Hiromichi Annoh, Tetsuya Saito, Ichiei Narita, Satoshi Waguri, Masaaki Komatsu.
    • Journal Title

      Journal of cell science

      Volume: 128 Pages: 4453-4461

    • DOI

      10.1242/jcs.180174

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830080, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-26860224
  • [Journal Article] The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates2015

    • Author(s)
      Morimoto, D., Walinda, E. Fukada, H., Sou, Y. S., Kageyama, S., Hoshino, M., Fujii, T., Tsuchiya, H., Saeki, Y., Arita, K., Ariyoshi, M., Tochio, H., Iwai, K., Namba, K., Komatsu, M., Tanaka, K., and Shirakawa M.
    • Journal Title

      Nat Commun.

      Volume: 6 Pages: 000-000

    • DOI

      10.1038/ncomms7116

    • NAID

      120005528125

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-21121006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-25000013, KAKENHI-PLANNED-25111006, KAKENHI-PUBLICLY-25112514, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-26440025, KAKENHI-PROJECT-26860224, KAKENHI-PROJECT-25253019, KAKENHI-PROJECT-26000014
  • [Journal Article] Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.2014

    • Author(s)
      Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, and Komatsu M.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 289 Pages: 24944-24955

    • DOI

      10.1074/jbc.m114.580357

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-26860224
  • [Journal Article] Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B positive structures.2014

    • Author(s)
      Lystad, AH., Ichimura, Y., Takagi, K., Yang, Y., Pankiv, S., Kanegae, Y., Kageyama, S., Suzuki, M., Saito, I., Mizushima,T., *Komatsu, M., *Simonsen, A.
    • Journal Title

      EMBO Report

      Volume: 15 Pages: 557-565

    • DOI

      10.1002/embr.201338003

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-25460400, KAKENHI-PROJECT-25870631, KAKENHI-PROJECT-26670221, KAKENHI-PROJECT-26860224
  • [Journal Article] オートファジーと疾患-Autophagy and disease states-2014

    • Author(s)
      小松雅明、蔭山俊
    • Journal Title

      新潟県医師会報

      Volume: 774 Pages: 1-9

    • Data Source
      KAKENHI-PROJECT-26860224
  • [Presentation] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2020

    • Author(s)
      Shun Kageyama, Sigurdur Runar Gudmundsson, Yu-Shin Sou, Yoshinobu Ichimura, Naoki Tamura, Saiko Kazuno, et al.
    • Organizer
      VIRTUAL KEYSTONE SYMPOSIA Autophagy: Mechanisms and Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06549
  • [Presentation] 選択的オートファジーの動態解析と生理的意義の解明2020

    • Author(s)
      蔭山 俊、Sigurdur Gudmundsson、曽 友深、一村義信、田村直輝、數野彩子、上野 隆、三浦芳樹、能代大輔、阿部 学、水島恒裕、三浦信明、奥田修二郎、本橋ほづみ、 Jin-A Lee、﨑村建司、大江知之、野田展生、和栗 聡、Eeva-Liisa Eskelinen、小松雅明
    • Organizer
      第72回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-20K06549
  • [Presentation] Nbr1 modulates the activation of the p62-Keap1-Nrf2 pathway during oxidative stress2019

    • Author(s)
      蔭山俊、Sanchez‐Martin Pablo、小松雅明
    • Organizer
      第12回オートファジー研究会 第1回新学術領域研究「マルチモードオートファジー」班会議
    • Data Source
      KAKENHI-PROJECT-18K15043
  • [Presentation] p62/SQSTM1液滴のオートファジー2019

    • Author(s)
      蔭山俊、Sigurdur Gudmundsson、一村義信、野田展生、和栗聡、Eeva-Liisa Eskelinen、小松雅明
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K15043
  • [Presentation] Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 in living cells2016

    • Author(s)
      Shun Kageyama, Atsushi Eino, Takefumi Uemura, Satoshi Waguri and Masaaki Komatsu
    • Organizer
      Joint Japan-Korea Young Investigator Conference on Autophagy (A3)
    • Place of Presentation
      NIIGATA MEDICAL PROFESSIONALS DEVELOPMENT CENTER, NIIGATA UNIVERSITY, 757, Ichibancho, Asahimachidori, Chuo-ku, Niigata-shi, Niigata, JAPAN
    • Year and Date
      2016-02-18
    • Data Source
      KAKENHI-PROJECT-26860224
  • [Presentation] Alfyによるメンブレントラフィック制御2015

    • Author(s)
      蔭山 俊、和栗 聡、鐘ヶ江 裕美、曽 友深、一村 義信、斎藤 泉、福田 光則、小松 雅明
    • Organizer
      BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸国際展示場 1号館1F、兵庫県神戸市中央区港島中町6丁目11-1
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-26860224
  • [Presentation] Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway2015

    • Author(s)
      S Kageyama; Y Sou; T Uemura; S Kametaka; T Saito; R Ishimura; T Kouno; R Mayer; L Bedford; M Lee; M Yamamoto; S Waguri; K Tanaka; M Komatsu
    • Organizer
      2015 Keystone Symposia Conference E6: Autophagy
    • Place of Presentation
      Beaver Run Resort, Breckenridge, Colorado
    • Year and Date
      2015-06-21
    • Data Source
      KAKENHI-PROJECT-26860224
  • [Presentation] Sqstm1-GFPノックインマウスを用いたSqstm1/p62の動態解析2015

    • Author(s)
      Eino A, Kageyama S, Uemura T, Annoh H, Saito T, Narita I, Waguri S, Komatsu M
    • Organizer
      第3 回新学術「オートファジー」班会議 (第9 回オートファジー研究会
    • Place of Presentation
      淡路夢舞台国際会議場、兵庫県淡路市夢舞台1
    • Year and Date
      2015-11-16
    • Data Source
      KAKENHI-PROJECT-26860224
  • [Presentation] プロテアソーム障害は選択的オートファジーとKeap1-Nrf2システムを活性化する2014

    • Author(s)
      蔭山俊、曽友深、植村武文、亀高諭、斉藤哲也、石村亮輔、河野亜華、Lynn Bedford、R. John Mayer、Myung-Shik Lee、山本 雅之、和栗聡、田中啓二、小松雅明
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜 展示ホール
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-26860224
  • [Presentation] Proteasome dysfunction activates autophagy and the Keap1-Nrf2 system2014

    • Author(s)
      Shun Kageyama, Yu-shin Sou, Takefumi Uemura, Satoshi Kametaka, Tetsuya Saito, Ryosuke Ishimura, Tsuguka Kouno, Lynn Bedford, R. John Maye, Myung-Shik Lee, Masayuki Yamamoto, Satoshi Waguri, Keiji Tanaka, and Masaaki Komatsu
    • Organizer
      第8回オートファジー研究会・第2回新学術「オートファジー」班会議
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ
    • Year and Date
      2014-11-10
    • Data Source
      KAKENHI-PROJECT-26860224
  • 1.  KOMATSU masaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 10 results
  • 2.  UEMURA Takefumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  KANEKO Yoshikatsu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  SATO Yuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  ITO Yuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  ICHIMURA Yoshinobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  NODA Nobuo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  NATSUME Rie
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  Zhou Lei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  Hossain MD Ibrahim
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  ARIYOSI Mariko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  SAEKI Yasushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  NAMBA Keiichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  山本 雅之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  和栗 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 16.  田中 啓二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  成田 一衛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  斎藤 亮彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  北村 信隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  曽 友深
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  能代 大輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  本橋 ほづみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  崎村 建司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 24.  大江 知之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  田村 直輝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  高木 賢治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  斎藤 泉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  SANCHEZ-MARTIN PABLO
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 29.  小池 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  阿部 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  今野 幸太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  竹林 浩秀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  田中 謙二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  白川 昌宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  杤尾 豪人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  岩井 一宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  星野 大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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