Kageyama Shun 蔭山俊

… Alternative Names

KAGEYAMA Shun 蔭山俊

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Researcher Number	30624225
Other IDs
Affiliation (Current)	2022: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2020: 順天堂大学, 医学部, 助教 2018: 新潟大学, 医歯学系, 助教 2014 – 2015: 新潟大学, 医歯学系, 助教
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 48040:Medical biochemistry-related / Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator オートファジー / p62 / プロテアソーム / ユビキチン / 凝集体 / Sqstm1/p62 / Nrf2 / Keap1 / ユビキチン-プロテアソームシステム / Atg7 … More / psmc1 / Sqstm1-GFP / Alfy / 小胞輸送経路 / 自閉症スペクトラム症 / 神経突起 / Rab / メンブレントラフィック / 選択的オートファジー / GABARAP / アダプタータンパク質 / 小胞輸送 / 液－液相分離 / 液滴 / LC3/GABARAP / Keap1-Nrf2経路 / p62/SQSTM1 / 相分離 Less

選択的オートファジー基質p62/SQSTM1液滴の分子病態の解析Principal Investigator
- Principal Investigator
  
  蔭山俊
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Juntendo University
Functional analysis of Alfy, a selective autophagy related molecule involved in brain formationPrincipal Investigator
- Principal Investigator
  
  Kageyama Shun
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Juntendo University
  Niigata University
Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathwayPrincipal Investigator
- Principal Investigator
  
  KAGEYAMA Shun
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Niigata University

All 2021 2020 2019 2018 2016 2015 2014

All Journal Article Presentation

[Journal Article] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2021
- Author(s)
  Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M.
- Journal Title
  
  Nat Commun.
  
  Volume: 12 Pages: 1-16
- DOI
  10.1038/s41467-020-20185-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07276, KAKENHI-PROJECT-20K06549, KAKENHI-PROJECT-20K06644, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-20H03415
[Journal Article] p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control2021
- Author(s)
  Eskelinen Eeva-Liisa、Kageyama Shun、Komatsu Masaaki
- Journal Title
  
  Molecular & Cellular Oncology
  
  Volume: 8 Pages: 1890990-1890990
- DOI
  10.1080/23723556.2021.1890990
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06549
[Journal Article] NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system.2020
- Author(s)
  Sanchez-Martin P, Sou YS, Kageyama S, Koike M, Waguri S, *Komatsu M.
- Journal Title
  
  EMBO Rep.
  
  Volume: 21
- DOI
  10.15252/embr.201948902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18F18099, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-18K15043, KAKENHI-PROJECT-16H06276
[Journal Article] Hyperosmotic Stress Induces Unconventional Autophagy Independent of the U1K1 Complex.2019
- Author(s)
  Tamura N, Kageyama S, Komatsu M, Waguri S.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 39
- DOI
  10.1128/mcb.00024-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-18K15043, KAKENHI-PROJECT-16H06276
[Journal Article] Deletion of exons encoding carboxypeptidase domain of Nnal results in Purkinje cell degeneration (pcd) phenotype.2018
- Author(s)
  Zhou L, Hossain MI, Yamazaki M, Abe M, Natsume R, Konno K, Kageyama S, Komatsu M, Watanabe M, Sakimura K, Takebayashi H.
- Journal Title
  
  J Neurochem.
  
  Volume: 147 Pages: 557-572
- DOI
  10.1111/jnc.14591
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-18K06813, KAKENHI-PROJECT-18K15043, KAKENHI-WRAPUP-18H05199, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-17K19444, KAKENHI-PLANNED-25117007, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02592
[Journal Article] Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease.2016
- Author(s)
  Kuwahara S, Hosojima M, Kaneko R, Aoki H, Nakano D, Sasagawa T, Kabasawa H, Kaseda R, Yasukawa R, Ishikawa T, Suzuki A, Sato H, Kageyama S, Tanaka T, Kitamura N, Narita I, Komatsu M, Nishiyama A, Saito A
- Journal Title
  
  Journal of the American Society of Nephrology.
  
  Volume: in press Pages: 1996-2008
- DOI
  10.1681/asn.2015020190
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670429, KAKENHI-PROJECT-26860224, KAKENHI-PROJECT-26293201, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-26461216, KAKENHI-PROJECT-15K11309
[Journal Article] オートファジーの誘導2015
- Author(s)
  蔭山俊
- Journal Title
  
  THE LUNG perspectives
  
  Volume: 23 Pages: 47-51
- Data Source
  KAKENHI-PROJECT-26860224
[Journal Article] Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells2015
- Author(s)
  Atsushi Eino, Shun Kageyama, Takefumi Uemura, Hiromichi Annoh, Tetsuya Saito, Ichiei Narita, Satoshi Waguri, Masaaki Komatsu.
- Journal Title
  
  Journal of cell science
  
  Volume: 128 Pages: 4453-4461
- DOI
  10.1242/jcs.180174
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830080, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-26860224
[Journal Article] The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates2015
- Author(s)
  Morimoto, D., Walinda, E. Fukada, H., Sou, Y. S., Kageyama, S., Hoshino, M., Fujii, T., Tsuchiya, H., Saeki, Y., Arita, K., Ariyoshi, M., Tochio, H., Iwai, K., Namba, K., Komatsu, M., Tanaka, K., and Shirakawa M.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Pages: 000-000
- DOI
  10.1038/ncomms7116
- NAID
  120005528125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-21121006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-25000013, KAKENHI-PLANNED-25111006, KAKENHI-PUBLICLY-25112514, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-26440025, KAKENHI-PROJECT-26860224, KAKENHI-PROJECT-25253019, KAKENHI-PROJECT-26000014
[Journal Article] Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.2014
- Author(s)
  Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, and Komatsu M.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Pages: 24944-24955
- DOI
  10.1074/jbc.m114.580357
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-26860224
[Journal Article] Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B positive structures.2014
- Author(s)
  Lystad, AH., Ichimura, Y., Takagi, K., Yang, Y., Pankiv, S., Kanegae, Y., Kageyama, S., Suzuki, M., Saito, I., Mizushima,T., *Komatsu, M., *Simonsen, A.
- Journal Title
  
  EMBO Report
  
  Volume: 15 Pages: 557-565
- DOI
  10.1002/embr.201338003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-25460400, KAKENHI-PROJECT-25870631, KAKENHI-PROJECT-26670221, KAKENHI-PROJECT-26860224
[Journal Article] オートファジーと疾患-Autophagy and disease states-2014
- Author(s)
  小松雅明、蔭山俊
- Journal Title
  
  新潟県医師会報
  
  Volume: 774 Pages: 1-9
- Data Source
  KAKENHI-PROJECT-26860224
[Presentation] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2020
- Author(s)
  Shun Kageyama, Sigurdur Runar Gudmundsson, Yu-Shin Sou, Yoshinobu Ichimura, Naoki Tamura, Saiko Kazuno, et al.
- Organizer
  VIRTUAL KEYSTONE SYMPOSIA Autophagy: Mechanisms and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06549
[Presentation] 選択的オートファジーの動態解析と生理的意義の解明2020
- Author(s)
  蔭山俊、Sigurdur Gudmundsson、曽友深、一村義信、田村直輝、數野彩子、上野隆、三浦芳樹、能代大輔、阿部学、水島恒裕、三浦信明、奥田修二郎、本橋ほづみ、 Jin-A Lee、﨑村建司、大江知之、野田展生、和栗聡、Eeva-Liisa Eskelinen、小松雅明
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-20K06549
[Presentation] Nbr1 modulates the activation of the p62-Keap1-Nrf2 pathway during oxidative stress2019
- Author(s)
  蔭山俊、Sanchez‐Martin Pablo、小松雅明
- Organizer
  第12回オートファジー研究会　第1回新学術領域研究「マルチモードオートファジー」班会議
- Data Source
  KAKENHI-PROJECT-18K15043
[Presentation] p62/SQSTM1液滴のオートファジー2019
- Author(s)
  蔭山俊、Sigurdur Gudmundsson、一村義信、野田展生、和栗聡、Eeva-Liisa Eskelinen、小松雅明
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15043
[Presentation] Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 in living cells2016
- Author(s)
  Shun Kageyama, Atsushi Eino, Takefumi Uemura, Satoshi Waguri and Masaaki Komatsu
- Organizer
  Joint Japan-Korea Young Investigator Conference on Autophagy (A3)
- Place of Presentation
  NIIGATA MEDICAL PROFESSIONALS DEVELOPMENT CENTER, NIIGATA UNIVERSITY, 757, Ichibancho, Asahimachidori, Chuo-ku, Niigata-shi, Niigata, JAPAN
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-26860224
[Presentation] Alfyによるメンブレントラフィック制御2015
- Author(s)
  蔭山俊、和栗聡、鐘ヶ江裕美、曽友深、一村義信、斎藤泉、福田光則、小松雅明
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸国際展示場 1号館1F、兵庫県神戸市中央区港島中町６丁目１１－１
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26860224
[Presentation] Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway2015
- Author(s)
  S Kageyama; Y Sou; T Uemura; S Kametaka; T Saito; R Ishimura; T Kouno; R Mayer; L Bedford; M Lee; M Yamamoto; S Waguri; K Tanaka; M Komatsu
- Organizer
  2015 Keystone Symposia Conference E6: Autophagy
- Place of Presentation
  Beaver Run Resort, Breckenridge, Colorado
- Year and Date
  2015-06-21
- Data Source
  KAKENHI-PROJECT-26860224
[Presentation] Sqstm1-GFPノックインマウスを用いたSqstm1/p62の動態解析2015
- Author(s)
  Eino A, Kageyama S, Uemura T, Annoh H, Saito T, Narita I, Waguri S, Komatsu M
- Organizer
  第3 回新学術「オートファジー」班会議 (第9 回オートファジー研究会
- Place of Presentation
  淡路夢舞台国際会議場、兵庫県淡路市夢舞台１
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-26860224
[Presentation] プロテアソーム障害は選択的オートファジーとKeap1-Nrf2システムを活性化する2014
- Author(s)
  蔭山俊、曽友深、植村武文、亀高諭、斉藤哲也、石村亮輔、河野亜華、Lynn Bedford、R. John Mayer、Myung-Shik Lee、山本雅之、和栗聡、田中啓二、小松雅明
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　展示ホール
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26860224
[Presentation] Proteasome dysfunction activates autophagy and the Keap1-Nrf2 system2014
- Author(s)
  Shun Kageyama, Yu-shin Sou, Takefumi Uemura, Satoshi Kametaka, Tetsuya Saito, Ryosuke Ishimura, Tsuguka Kouno, Lynn Bedford, R. John Maye, Myung-Shik Lee, Masayuki Yamamoto, Satoshi Waguri, Keiji Tanaka, and Masaaki Komatsu
- Organizer
  第8回オートファジー研究会・第2回新学術「オートファジー」班会議
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ
- Year and Date
  2014-11-10
- Data Source
  KAKENHI-PROJECT-26860224

1. KOMATSU masaaki

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# of Collaborated Products: 10 results
2. UEMURA Takefumi

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# of Collaborated Products: 2 results
3. KANEKO Yoshikatsu

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# of Collaborated Products: 1 results
4. SATO Yuya

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# of Collaborated Products: 1 results
5. ITO Yuko

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6. ICHIMURA Yoshinobu

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7. NODA Nobuo

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8. NATSUME Rie

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9. Zhou Lei

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10. Hossain MD Ibrahim

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11. ARIYOSI Mariko

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12. SAEKI Yasushi

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13. NAMBA Keiichi

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14. 山本雅之

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15. 和栗聡

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16. 田中啓二

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17. 成田一衛

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18. 斎藤亮彦

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19. 北村信隆

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20. 曽友深

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21. 能代大輔

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22. 本橋ほづみ

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23. 崎村建司

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24. 大江知之

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25. 田村直輝

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26. 高木賢治

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27. 斎藤泉

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28. SANCHEZ-MARTIN PABLO

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29. 小池正人

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30. 阿部学

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31. 今野幸太郎

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32. 竹林浩秀

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33. 田中謙二

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34. 白川昌宏

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35. 杤尾豪人

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36. 岩井一宏

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37. 星野大

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Kageyama Shun 蔭山 俊

KAGEYAMA Shun 蔭山 俊

Research Projects

Research Products

Co-Researchers

選択的オートファジー基質p62/SQSTM1液滴の分子病態の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of Alfy, a selective autophagy related molecule involved in brain formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hyperosmotic Stress Induces Unconventional Autophagy Independent of the U1K1 Complex.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deletion of exons encoding carboxypeptidase domain of Nnal results in Purkinje cell degeneration (pcd) phenotype.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] オートファジーの誘導2015

Author(s)

Journal Title

Data Source

[Journal Article] Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B positive structures.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] オートファジーと疾患-Autophagy and disease states-2014

Author(s)

Kageyama Shun 蔭山俊

KAGEYAMA Shun 蔭山俊