Naoi Yasuto 直居靖人

Researcher Number	30646211
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2025: 大阪大学, 大学院医学系研究科, 招へい教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2022 – 2023: 大阪大学, 大学院医学系研究科, 招へい教授 2021: 大阪大学, 医学系研究科, 招へい教授 2020: 大阪大学, 医学系研究科, 准教授 2016 – 2018: 大阪大学, 医学系研究科, 助教 2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Basic Section 10030:Clinical psychology-related / Basic Section 52040:Radiological sciences-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / General surgery
Keywords	Principal Investigator マイクロアレイ / 乳癌 / 網羅的遺伝子発現解析 / 多重遺伝子診断法 / 多遺伝子診断法 / Curebest 95GC / RNA sequence / RNA / FFPE / 多遺伝子アッセイ … More / 再発予測 / 転移予測 / 腋窩リンパ節 / 腋窩リンパ節転移 / 多重遺伝子診断 … More Except Principal Investigator 乳癌 / 高齢者 / 治療選択 / 意思決定 / well-being / 病理学的完全奏功 / 術前化学療法 / pCR / Neoadjuvant chemotherapy / Radiogenomics / MRI / Breast cancer / 質量分析イメージング / TGF-β / 抗HER2抗体 / HER2陽性乳癌 / trastuzumab / TGFβ / 癌幹細胞 / ラパチニブ / トラスツズマブ / SMAD3 / TGF-beta / HER2 Less

Comprehensive examination of factors related to well-being on medical decision-making
- Principal Investigator
  
  加藤佑佳
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 10030:Clinical psychology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Investigating the heterogeneity and drug sensitivity of breast cancer based on mass spectrometry imaging
- Principal Investigator
  
  加藤千翔
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Construction of Radiogenomics Prediction Model for Pathological Complete Response after Preoperative Chemotherapy for Breast Cancer
- Principal Investigator
  
  徳田由紀子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Osaka University
RNAseq analysis for Curebest 95GCPrincipal Investigator
- Principal Investigator
  
  Naoi Yasuto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka University
Development of recurrence risk prediction model 95-gene classifier and its application to formalin-fixed paraffin-embedded tissues.Principal Investigator
- Principal Investigator
  
  Naoi Yasuto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Involvement of TGF-beta/SMAD signaling in trastuzumab resistance
- Principal Investigator
  
  Shimoda Masafumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Development of a prediction model for lymph node metastasis in luminal A subtype breast cancerPrincipal Investigator
- Principal Investigator
  
  Naoi Yasuto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University

All 2023 2022 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Validation of the prognosis of patients with ER-positive, HER2-negative and node-negative invasive breast cancer classified as low risk by Curebest 95GC Breast in a multi-institutional registry study2023
- Author(s)
  Naoi Yasuto、Tsunashima Ryo、Shimazu Kenzo、Oikawa Masahiro、Imanishi Seiichi、Koyama Hiroshi、Kamada Yoshihiko、Ishihara Kazuhiro、Suzuki Masahiko、Osako Tomo、Kinoshita Takayuki、Suto Akihiko、Nakamura Seigo、Tsuda Hitoshi、Noguchi Shinzaburo
- Journal Title
  
  Oncology Letters
  
  Volume: 25 Issue: 5 Pages: 209-209
- DOI
  10.3892/ol.2023.13794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09075, KAKENHI-PROJECT-20K08926
[Journal Article] Curebest 95GC -日本で開発された多遺伝子発現解析-2017
- Author(s)
  直居　靖人
- Journal Title
  
  Current Therapy
  
  Volume: Vol.35, No.9
- Data Source
  KAKENHI-PROJECT-16K10456
[Journal Article] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Journal Title
  
  日本臨床
  
  Volume: 75巻　増刊号3
- Data Source
  KAKENHI-PROJECT-16K10456
[Journal Article] Development of a prediction model for lymph node metastasis in luminal A subtype breast cancer: the possibility to omit sentinel lymph node biopsy.2014
- Author(s)
  Nakauchi C, Naoi Y, Shimazu K, Tsunashima R, Nishio M, Maruyama N, Shimomura A, Kagara N, Shimoda M, Kim SJ, Noguchi S.
- Journal Title
  
  Cancer Lett.
  
  Volume: Oct 10;353(1) Issue: 1 Pages: 52-8
- DOI
  10.1016/j.canlet.2014.07.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461981
[Journal Article] 72-gene classifier for predicting prognosis of estrogen receptor-positive and node-negative breast cancer patients using formalin-fixed, paraffin-embedded tumor tissues.2014
- Author(s)
  Nishio M, Naoi Y, Tsunashima R, Nakauchi C, Kagara N, Shimoda M, Shimomura A, Maruyama N, Shimazu K, Kim SJ, Noguchi S.
- Journal Title
  
  Clin Breast Cancer
  
  Volume: Jun;14(3) Issue: 3 Pages: e73-e80
- DOI
  10.1016/j.clbc.2013.11.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461981
[Journal Article] Construction of novel immune-related signature for prediction of pathological complete response to neoadjuvant chemotherapy in human breast cancer.2014
- Author(s)
  Sota Y, Naoi Y, Tsunashima R, Kagara N, Shimazu K, Maruyama N, Shimomura A, Shimoda M, Kishi K, Baba Y, Kim SJ, Noguchi S.
- Journal Title
  
  Ann Oncol.
  
  Volume: Jan;25(1) Issue: 1 Pages: 100-6
- DOI
  10.1093/annonc/mdt427
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461981
[Presentation] 閉経期乳癌の治療2023
- Author(s)
  直居　靖人
- Organizer
  日本乳癌学会2023シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K08926
[Presentation] 95GCを用いた乳癌オーダーメイド医療2022
- Author(s)
  直居靖人
- Organizer
  日本乳癌学会2022シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K08926
[Presentation] Curebest 95GCを用いた乳癌再発予後予測2018
- Author(s)
  直居靖人
- Organizer
  日本乳癌学会シンポジウム
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  乳癌学会中部地方会2017　ランチョンセミナー
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  23th. Asia pacific cancer conference (APCC), symposium in Seoul
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  日本乳癌学会学術総会2017　プレジデンシャルシンポジウム
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  日本癌治療学会2017　学術セミナー
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  がんと生殖に関するシンポジウム2017　ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  第73回　京滋乳癌研究会　特別講演
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  第64回　日本臨床検査医学会学術集会　ランチョンセミナー
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  日本乳癌学会九州地方会2017　ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  乳癌最新情報カンファレンス2017 特別講演
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多重遺伝子診断法の開発と臨床応用2017
- Author(s)
  直居　靖人
- Organizer
  第15回　日本臨床腫瘍学会学術集会　WS
- Invited
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] Curebest 95GCによる乳癌再発予後予測2016
- Author(s)
  直居靖人
- Organizer
  日本臨床腫瘍学会
- Place of Presentation
  神戸
- Year and Date
  2016-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 多遺伝子アッセイの開発と乳癌臨床応用2016
- Author(s)
  直居靖人
- Organizer
  日本乳癌学会
- Place of Presentation
  東京
- Year and Date
  2016-06-22
- Data Source
  KAKENHI-PROJECT-16K10456
[Presentation] 乳癌個別化医療を実現する分子診断の展望2015
- Author(s)
  直居　靖人
- Organizer
  日本病理学会総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-05-01
- Invited
- Data Source
  KAKENHI-PROJECT-25461981
[Presentation] 乳癌新規バイオマーカー　～予後予測から感受性予測まで2014
- Author(s)
  直居靖人
- Organizer
  Osaka breast cancer workshop 2014 招待講演
- Place of Presentation
  大阪
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-25461981
[Presentation] マイクロアレイによる乳癌の新分類学2014
- Author(s)
  直居靖人
- Organizer
  第26回　大阪若手がんセミナー　招待講演
- Place of Presentation
  大阪
- Year and Date
  2014-07-15
- Invited
- Data Source
  KAKENHI-PROJECT-25461981
[Presentation] 疾患マーカーの探索と利用
- Author(s)
  直居靖人
- Organizer
  第87回日本生化学会大会　フォーラム　招待講演，2F07
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25461981
[Presentation] 95GC as a Predictor of Recurrence Risk for ER+/Node- Breast Cancer Patients
- Author(s)
  直居靖人
- Organizer
  第114回　日本外科学会定期学術集会　ワークショップ　招待講演
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-04-03 – 2014-04-05
- Invited
- Data Source
  KAKENHI-PROJECT-25461981

1. Shimoda Masafumi (30644455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 加藤千翔 (10970890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 徳田由紀子 (50522744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 梁川雅弘 (00546872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 鈴木裕紀 (20845599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 富山憲幸 (50294070)

# of Collaborated Projects: 1 results

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7. 木戸尚治 (90314814)

# of Collaborated Projects: 1 results

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8. 加藤佑佳 (60729268)

# of Collaborated Projects: 1 results

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9. 妹尾恵太郎 (70822584)

# of Collaborated Projects: 1 results

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10. 大庭輝 (60783412)

# of Collaborated Projects: 1 results

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11. CHIHARA Yoko

# of Collaborated Projects: 1 results

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12. 及川将弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Naoi Yasuto 直居 靖人

Research Projects

Research Products

Co-Researchers

Comprehensive examination of factors related to well-being on medical decision-making

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigating the heterogeneity and drug sensitivity of breast cancer based on mass spectrometry imaging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of Radiogenomics Prediction Model for Pathological Complete Response after Preoperative Chemotherapy for Breast Cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNAseq analysis for Curebest 95GCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of recurrence risk prediction model 95-gene classifier and its application to formalin-fixed paraffin-embedded tissues.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of TGF-beta/SMAD signaling in trastuzumab resistance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a prediction model for lymph node metastasis in luminal A subtype breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Validation of the prognosis of patients with ER-positive, HER2-negative and node-negative invasive breast cancer classified as low risk by Curebest 95GC Breast in a multi-institutional registry study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Curebest 95GC -日本で開発された多遺伝子発現解析-2017

Author(s)

Journal Title

Data Source

[Journal Article] 多重遺伝子診断法の開発と臨床応用2017

Author(s)

Journal Title

Data Source

[Journal Article] Development of a prediction model for lymph node metastasis in luminal A subtype breast cancer: the possibility to omit sentinel lymph node biopsy.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 72-gene classifier for predicting prognosis of estrogen receptor-positive and node-negative breast cancer patients using formalin-fixed, paraffin-embedded tumor tissues.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of novel immune-related signature for prediction of pathological complete response to neoadjuvant chemotherapy in human breast cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 閉経期乳癌の治療2023

Author(s)

Organizer

Data Source

[Presentation] 95GCを用いた乳癌オーダーメイド医療2022

Author(s)

Naoi Yasuto 直居靖人

[Presentation] 乳癌新規バイオマーカー　～予後予測から感受性予測まで2014