Maekawa Tatsunori 前川達則

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MAEKAWA Tatsunori 前川達則

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Researcher Number	30647673
Other IDs	https://orcid.org/0000-0002-1214-9959
Affiliation (Current)	2024: 北里大学, 医療衛生学部, 講師
Affiliation (based on the past Project Information) *help	2018 – 2023: 北里大学, 医療衛生学部, 講師 2013 – 2014: 北里大学, 医療衛生学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Neurology
Keywords	Principal Investigator LRRK2 / パーキンソン病 / 腸管神経系 / 腸管神経 / alpha-synuclein / 水膜輸送 / 消化管症状 / 消化管運動 / αシヌクレイン / ミクログリア

腸管神経におけるalphaシヌクレインの凝集と水膜輸送の関係Principal Investigator
- Principal Investigator
  
  前川達則
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kitasato University
The role of LRRK2 in enteric neurogenesis and the pathogenesis of Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  Tatsunori Maekawa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kitasato University
The role of LRRK2 in dysfunction of enteric nervous systemPrincipal Investigator
- Principal Investigator
  
  Maekawa Tatsunori
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kitasato University
Analysis of LRRK2-function in microglial alpha-synuclein clearancePrincipal Investigator
- Principal Investigator
  
  MAEKAWA Tatsunori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University

All 2023 2022 2020 2019 2018 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells2023
- Author(s)
  Kawakami Fumitaka、Imai Motoki、Tamaki Shun、Ohta Etsuro、Kawashima Rei、Maekawa Tatsunori、Kurosaki Yoshifumi、Ohba Kenichi、Ichikawa Takafumi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 1 Pages: 123-127
- DOI
  10.1248/bpb.b22-00356
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08294, KAKENHI-PROJECT-22K07993, KAKENHI-PROJECT-19K08379, KAKENHI-PROJECT-20K06914, KAKENHI-PROJECT-20K07764, KAKENHI-PROJECT-20K21727, KAKENHI-PUBLICLY-21H00436
[Journal Article] Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells2020
- Author(s)
  Kubo Makoto、Nagashima Ryuichi、Kurihara Mitsue、Kawakami Fumitaka、Maekawa Tatsunori、Eshima Koji、Ohta Etsuro、Kato Hirotomo、Obata Fumiya
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 5 Pages: 1890-1890
- DOI
  10.3390/ijms21051890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19460, KAKENHI-PUBLICLY-19H05428, KAKENHI-PROJECT-17H01685, KAKENHI-PROJECT-18K15374
[Journal Article] Leucine-Rich Repeat Kinase 2 Is Associated With Activation of the Paraventricular Nucleus of the Hypothalamus and Stress-Related Gastrointestinal Dysmotility2019
- Author(s)
  Maekawa Tatsunori、Tsushima Hiromichi、Kawakami Fumitaka、Kawashima Rei、Kodo Masaru、Imai Motoki、Ichikawa Takafumi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 13 Pages: 905-905
- DOI
  10.3389/fnins.2019.00905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09392, KAKENHI-PROJECT-19K08379, KAKENHI-PROJECT-16K09323, KAKENHI-PROJECT-18K15374
[Journal Article] The mouse/human cross-species heterodimer of leucine-rich repeat kinase 2: Possible significance in the transgenic model mouse of Parkinson's disease.2015
- Author(s)
  Miyajima T, Ohta E, Kawada H, Maekawa T, Obata F
- Journal Title
  
  Neuroscience Letters
  
  Volume: 588 Pages: 142-146
- DOI
  10.1016/j.neulet.2015.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860720
[Journal Article] Leucine-rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase-3β.2014
- Author(s)
  Kawakami F, Shimada N, Ohta E, Kagiya G, Kawashima R, Maekawa T, Maruyama H, Ichikawa T.
- Journal Title
  
  FEBS J.
  
  Volume: 281 Issue: 1 Pages: 3-13
- DOI
  10.1111/febs.12579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461026, KAKENHI-PROJECT-25860720
[Presentation] 腸管神経系におけるαシヌクレインの局在解析2023
- Author(s)
  太田成海, 前川達則, 玉木竣, 川上文貴, 川島麗, 市川尊文
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07764
[Presentation] グリア細胞からの腸管神経新生におけるLRRK2の役割の解明2022
- Author(s)
  前川達則
- Organizer
  日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20K07764
[Presentation] Leucine-Rich Repeat Kinase 2変異マウスにおける大腸運動異常と腸管神経病理像2020
- Author(s)
  前川達則, 川島麗, 川上文貴, 市川尊文
- Organizer
  第21回日本神経消化器病学会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] 消化管におけるLRRK2のIBDリスク遺伝子としての生理的役割の解析2019
- Author(s)
  石川勇太, 川上文貴, 川島麗, 前川達則, 市川尊文
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] 腸管神経におけるLeucine-Rich Repeat Kinase 2の機能解析2019
- Author(s)
  前川達則, 川上文貴, 川島麗, Jaime Foong, Joel Bornstein, 市川尊文
- Organizer
  第37回Cytoprotection研究会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] 大腸炎モデルマウスを用いた高脂肪食摂取の腸管粘膜バリアへの影響解析2019
- Author(s)
  山下真裕佳, 川上文貴, 石川勇太, 今井基貴, 川島麗, 前川達則, 市川尊文
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] 腸管神経・グリア初代培養細胞を用いたLRRK2の機能解析2019
- Author(s)
  元川立一, 前川達則, 市川尊文
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] LRRK2による腸管神経新生調節機構の解明2019
- Author(s)
  元川立一, 前川達則, 市川尊文
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] 絶食下における腸管ムチンの発現変動と水分保持機構の解明2019
- Author(s)
  玉木竣, 川島麗, 二反田千里, 川上貴文, 前川達則, 栗原誠, 市川尊文
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] ATYPICAL MOTILITY PATTERNS IN GUT PREPARATION OF LRRK2 KNOCKOUT MICE2019
- Author(s)
  Tatsunori Maekawa, Fumitaka Kawakami, Rei Kawashima, Joel Bornstein, Jaime Foong, Takafumi Ichikawa
- Organizer
  9th FAOPS CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] 脂肪組織における糖代謝に対するLRRK2の生理的役割の解析2019
- Author(s)
  今井基貴, 川上文貴, 井阪勇輝, 川島麗, 前川達則, 神崎展
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] IBDリスク分子LRRK2の消化管におけるDSS腸炎に対する影響2019
- Author(s)
  石川勇太, 川上文貴, 川島麗, 前川達則, 市川尊文
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] LRRK2-Rab経路によるGLUT4膜輸送の調節メカニズム2019
- Author(s)
  今井基貴, 川上文貴, 川島麗, 前川達則, 神崎展, 市川尊文
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] Atypical motility pattern in gut preparation of LRRK2 knockout mice accompanied by aberrant enteric neurogenesis.2019
- Author(s)
  Tatsunori Maekawa, Fumitaka Kawakami, Rei Kawashima, Takafumi Ichikawa
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] 抗癌剤起因性腸管粘膜炎症におけるアミノ酸トランスポーターLAT発現の意義2019
- Author(s)
  玉木竣, 川島麗, 香渡優, 川上文貴, 前川達則, 栗原誠, 市川尊文
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] LRRK2 is associated with gastrointestinal dysmotility induced by restraint stress.2018
- Author(s)
  前川達則, 津島博道, 川上文貴, 川島麗, 市川尊文
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15374
[Presentation] LRRK2によるGSK-3βの活性化を介したタウのリン酸化調節2013
- Author(s)
  川上文貴、川島麗、前川達則、嶋山ひとみ、石原和彦、市川尊文
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-25860720
[Presentation] Alpha-synuclein分解におけるミクログリア-LRRK2の機能解析2013
- Author(s)
  前川達則、久保誠、市川尊文、小幡文弥
- Organizer
  第25回日本神経免疫学会学術集会
- Place of Presentation
  海峡メッセ (山口県下関市）
- Data Source
  KAKENHI-PROJECT-25860720
[Presentation] 腸管粘膜防御機構におけるLRRK2の機能解析
- Author(s)
  嶋山ひとみ、川上文貴、前川達則、山下博徳、市川尊文
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館 (京都府京都市)
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860720
[Presentation] 5-Fluorouracil起因性消化管粘膜傷害に対する成分栄養剤の効果
- Author(s)
  川島麗、雲井利亮、菅原節子、前川達則、川上文貴、石原和彦、市川尊文
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館 (京都府京都市)
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860720
[Presentation] α-synuclein分解におけるミクログリア-LRRK2の機能解析
- Author(s)
  前川達則、市川尊文、小幡文弥
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良県文化会館 (奈良県奈良市)
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25860720
[Presentation] α-synuclein分解におけるミクログリア-LRRK2の機能解析
- Author(s)
  前川達則、小幡文弥、市川尊文
- Organizer
  第26回日本神経免疫学会学術集会
- Place of Presentation
  金沢歌劇座 (石川県金沢市)
- Year and Date
  2014-09-04 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-25860720

1. 太田悦朗 (60508042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 永井真貴子 (80420488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KAWASHIMA Rei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. KATO Hirotomo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. KAWAKAMI Fumitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 市川尊文

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Maekawa Tatsunori 前川 達則

MAEKAWA Tatsunori 前川 達則

Research Projects

Research Products

Co-Researchers

腸管神経におけるalphaシヌクレインの凝集と水膜輸送の関係Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of LRRK2 in enteric neurogenesis and the pathogenesis of Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of LRRK2 in dysfunction of enteric nervous systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of LRRK2-function in microglial alpha-synuclein clearancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Leucine-Rich Repeat Kinase 2 Is Associated With Activation of the Paraventricular Nucleus of the Hypothalamus and Stress-Related Gastrointestinal Dysmotility2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The mouse/human cross-species heterodimer of leucine-rich repeat kinase 2: Possible significance in the transgenic model mouse of Parkinson's disease.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Leucine-rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase-3β.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 腸管神経系におけるαシヌクレインの局在解析2023

Author(s)

Organizer

Data Source

[Presentation] グリア細胞からの腸管神経新生におけるLRRK2の役割の解明2022

Author(s)

Organizer

Data Source

[Presentation] Leucine-Rich Repeat Kinase 2変異マウスにおける大腸運動異常と腸管神経病理像2020

Author(s)

Organizer

Data Source

[Presentation] 消化管におけるLRRK2のIBDリスク遺伝子としての生理的役割の解析2019

Author(s)

Organizer

Data Source

[Presentation] 腸管神経におけるLeucine-Rich Repeat Kinase 2の機能解析2019

Author(s)

Organizer

Data Source

[Presentation] 大腸炎モデルマウスを用いた高脂肪食摂取の腸管粘膜バリアへの影響解析2019

Author(s)

Organizer

Maekawa Tatsunori 前川達則

MAEKAWA Tatsunori 前川達則