Ishikawa Hiroki 石川裕規

… Alternative Names

石川裕規イシカワヒロキ

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Researcher Number	30648621
Other IDs
Affiliation (Current)	2026: 安田女子大学, 理工学部, 教授
Affiliation (based on the past Project Information) *help	2026: 安田女子大学, 理工学部, 教授 2024: 安田女子大学, 理工学部, 教授 2023 – 2024: 沖縄科学技術大学院大学, 免疫シグナルユニット, 准教授 2019 – 2020: 沖縄科学技術大学院大学, 免疫シグナルユニット, 准教授 2014 – 2017: 沖縄科学技術大学院大学, 免疫シグナルユニット, 准教授 2015: 沖縄科学技術大学院大学, その他の研究科, 准教授
Review Section/Research Field	Principal Investigator Immunology / Basic Section 48040:Medical biochemistry-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields Except Principal Investigator Basic Section 38060:Applied molecular and cellular biology-related
Keywords	Principal Investigator ヘルパーT細胞 / 自己免疫疾患 / 転写制御 / エピジェネティック制御 / T細胞 / 病原性 / 分化 / Th17細胞 / 転写因子 / 解糖 … More / AP-1転写因子 / AP-1 / JunB / 分化制御 / ナイーブT細胞 / RNA / Th17 … More Except Principal Investigator 膜損傷 / 免疫機能 / 高齢 Less

T細胞膜損傷応答の制御による抗腫瘍免疫活性化機構の解明とがん免疫療法への応用Principal Investigator
- Principal Investigator
  
  石川裕規
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Yasuda Women's University
Understanding and application of the mechanism by which glycolysis and JunB regulates chromatin states in autoimmune T cellsPrincipal Investigator
- Principal Investigator
  
  石川裕規
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Yasuda Women's University
  Okinawa Institute of Science and Technology Graduate University
インフルエンザウイルス感染後の二次性細菌性肺炎が高齢で重症化するメカニズムの解明
- Principal Investigator
  
  玉井美保
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Yasuda Women's University
Analysis of molecular mechanisms required for differentiation potential of naive T cellsPrincipal Investigator
- Principal Investigator
  
  Ishikawa Hiroki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Analysis of epigenetic regulatory mechanisms of Th17 differentiationPrincipal Investigator
- Principal Investigator
  
  Ishikawa Hiroki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Mechanism of transcriptional regulation of differentiation of pathogenic Th17 cellsPrincipal Investigator
- Principal Investigator
  
  Ishikawa Hiroki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Okinawa Institute of Science and Technology Graduate University

All 2025 2024 2023 2020 2019 2017 2015

All Journal Article Presentation Book

[Book] STING: a new adjuvant target2017
- Author(s)
  Hiroki Ishikawa
- Total Pages
  6
- Publisher
  CMC
- Data Source
  KAKENHI-PROJECT-16K19164
[Journal Article] JunB is required for CD8+ T cell responses to acute infections.2025
- Author(s)
  Sarkar S, Taira N, Hsieh TH, Chien HC, Hirota M, Koizumi SI, Sasaki D, Tamai M, Seto Y, Miyagi M, Ishikawa H.
- Journal Title
  
  International Immunology
  
  Volume: 37 Issue: 4 Pages: 203-220
- DOI
  10.1093/intimm/dxae063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19440, KAKENHI-PROJECT-23K27326, KAKENHI-PROJECT-24KJ2181
[Journal Article] Aging impairs CD8 T cell responses in adoptive T-cell therapy against solid tumors2025
- Author(s)
  Kadyrzhanova Gulfiya、Tamai Miho、Sarkar Shukla、Kalra Rajkumar Singh、Ishikawa Hiroki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 16 Pages: 1484303-1484303
- DOI
  10.3389/fimmu.2025.1484303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27326, KAKENHI-PROJECT-24K08838
[Journal Article] Engineered protein subunit COVID19 vaccine is as immunogenic as nanoparticles in mouse and hamster models2024
- Author(s)
  Matthews Melissa M.、Kim Tae Gyun、Kim Keon Young、Meshcheryakov Vladimir、Iha Higor Alves、Tamai Miho、Sasaki Daiki、Laurino Paola、Toledo-Pati?o Saacnicteh、Collins Mary、Hsieh Tzung-Yang、Shibata Satoshi、Shibata Noriko、Obata Fumiko、Fujii Jun、Ito Toshihiro、Ito Hiroshi、Ishikawa Hiroki、Wolf Matthias
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 25528-25528
- DOI
  10.1038/s41598-024-76377-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27326
[Journal Article] Cellular and molecular insights into the individual difference in COVID-19 mRNA vaccine responses2024
- Author(s)
  ISHIKAWA Hiroki、HIROTA Masato、TAMAI Miho
- Journal Title
  
  Translational and Regulatory Sciences
  
  Volume: 6 Issue: 1 Pages: 15-19
- DOI
  10.33611/trs.2023-008
- ISSN
  2434-4974
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27326
[Journal Article] Human immune and gut microbial parameters associated with inter-individual variations in COVID-19 mRNA vaccine-induced immunity2023
- Author(s)
  Hirota M., Tamai M., Yukawa S.,Taira N., Matthews M.M., Toma T., Seto Y., Yoshida M., Toguchi S., Miyagi M., Mori T., Tomori H., Tamai O., Kina M., Sakihara E., Yamashiro C., Miyagi M., Tamaki K., Wolf M., Collins M.K., Kitano H., Ishikawa H.
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 368-368
- DOI
  10.1038/s42003-023-04755-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20655, KAKENHI-PROJECT-23K27326
[Journal Article] Effect of Ethanol Vapor Inhalation Treatment on Lethal Respiratory Viral Infection With Influenza A2023
- Author(s)
  Tamai Miho、Taba Seita、Mise Takeshi、Yamashita Masao、Ishikawa Hiroki、Shintake Tsumoru
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 228 Issue: 12 Pages: 1720-1729
- DOI
  10.1093/infdis/jiad089
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27326
[Journal Article] The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression2020
- Author(s)
  Ito-Kureha Taku、Miyao Takahisa、Nishijima Saori、Suzuki Toru、Koizumi Shin-ichi、Villar-Briones Alejandro、Takahashi Akinori、Akiyama Nobuko、Morita Masahiro、Naguro Isao、Ishikawa Hiroki、Ichijo Hidenori、Akiyama Taishin、Yamamoto Tadashi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 6169-6169
- DOI
  10.1038/s41467-020-19975-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07079, KAKENHI-PROJECT-20K07332, KAKENHI-PUBLICLY-19H04821, KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-17K08622, KAKENHI-PROJECT-18K07237, KAKENHI-PROJECT-19K22547, KAKENHI-PROJECT-20H03441
[Journal Article] Transcriptional Regulation of Differentiation and Functions of Effector T Regulatory Cells2019
- Author(s)
  Koizumi S and Ishikawa H
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 8 Pages: 939-939
- DOI
  10.3390/cells8080939
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22547, KAKENHI-PROJECT-18K15201
[Journal Article] JunB is essential for IL-23-dependent pathogenicity of Th17 cells.2017
- Author(s)
  Hasan Z, Koizumi SI, Sasaki D, Yamada H, Arakaki N, Fujihara Y, Okitsu S, Shirahata H, Ishikawa H
- Journal Title
  
  Nature communications
  
  Volume: 8 Pages: 15628-15628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19164
[Presentation] Anti-tumor response to adoptive T cell therapy with aged CD8 T cells2024
- Author(s)
  Miho Tamai, Gulfiya Kadyrzhanova, Hiroki Ishikawa
- Organizer
  1st International Symposium on Living Systems Design Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K08838
[Presentation] JunB-dependent regulation of Th17 pathogenicity.2017
- Author(s)
  Hiroki Ishikawa
- Organizer
  The 2nd Design Biology Engineering Study Group Meeting
- Place of Presentation
  兵庫県、神戸ポートアイランド
- Year and Date
  2017-03-21
- Invited
- Data Source
  KAKENHI-PROJECT-16K19164
[Presentation] JunB-dependent generation of pathogenic Th17 cells2017
- Author(s)
  Hiroki Ishikawa
- Organizer
  24th East Asia Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19164
[Presentation] HLX1 regulates differentiation and function of CD4 helper T cells2015
- Author(s)
  石川裕規
- Organizer
  22nd East Asia Joint Symposium on Biomedical Research
- Place of Presentation
  沖縄科学技術大学院大学
- Year and Date
  2015-11-11
- Data Source
  KAKENHI-PROJECT-26860342

1. 玉井美保 (20619704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 山本雅 (40134621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小泉真一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 鈴木亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishikawa Hiroki 石川 裕規

石川 裕規 イシカワ ヒロキ

Research Projects

Research Products

Co-Researchers

T細胞膜損傷応答の制御による抗腫瘍免疫活性化機構の解明とがん免疫療法への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding and application of the mechanism by which glycolysis and JunB regulates chromatin states in autoimmune T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

インフルエンザウイルス感染後の二次性細菌性肺炎が高齢で重症化するメカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanisms required for differentiation potential of naive T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of epigenetic regulatory mechanisms of Th17 differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of transcriptional regulation of differentiation of pathogenic Th17 cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] STING: a new adjuvant target2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] JunB is required for CD8+ T cell responses to acute infections.2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aging impairs CD8 T cell responses in adoptive T-cell therapy against solid tumors2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Engineered protein subunit COVID19 vaccine is as immunogenic as nanoparticles in mouse and hamster models2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular and molecular insights into the individual difference in COVID-19 mRNA vaccine responses2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Human immune and gut microbial parameters associated with inter-individual variations in COVID-19 mRNA vaccine-induced immunity2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Ethanol Vapor Inhalation Treatment on Lethal Respiratory Viral Infection With Influenza A2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression2020

Author(s)

Ishikawa Hiroki 石川裕規

石川裕規イシカワヒロキ