Matsunaga Shinji 松永慎司

Researcher Number	30704910
Other IDs
Affiliation (Current)	2021: 大阪市立大学, 大学院医学研究科, 講師
Affiliation (based on the past Project Information) *help	2017 – 2020: 大阪市立大学, 大学院医学研究科, 講師 2016: 大阪市立大学, 大学院医学研究科, 助教 2015: 鳥取大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Basic Section 48030:Pharmacology-related Except Principal Investigator General pharmacology
Keywords	Principal Investigator 腫瘍 / 血管再構築 / マクロファージ / 薬理学 / 血管正常化 / 腫瘍血管 / 血管リモデリング / 血管内皮 / 薬物動態 / 血管 / 腫瘍微小環境 / 腫瘍免疫 … More Except Principal Investigator … More

腫瘍微小環境改善薬による抗腫瘍免疫応答制御機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  松永慎司
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Osaka City University
Basic research of cancer therapy by improving anticancer drug sensitivity through tumor vascular remodeling
- Principal Investigator
  
  Tomita Shuhei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka City University
The effects of PHD inhibitor on tumor blood vessel normalizationPrincipal Investigator
- Principal Investigator
  
  Matsunaga Shinji
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka City University
Tumor blood vessel normalization by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumor mouse model
- Principal Investigator
  
  Tomita Shuhei
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Osaka City University
  Tottori University

All 2019 2018 2017 2016 2015

All Journal Article Presentation Book Patent

[Book] 尿酸と血糖「第5回忙しい人のための抄読会」2016
- Author(s)
  松永慎司，冨田修平
- Total Pages
  4
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-15K15054
[Book] 医学のあゆみ（別冊）レドックスUPDATE「血管リモデリングにおける低酸素応答性転写因子の役割」2015
- Author(s)
  冨田修平, 松永慎司
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-15K15054
[Journal Article] A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4.2019
- Author(s)
  Yamaguchi Takehiro、Watanabe Ayano、Tanaka Masako、Shiota Masayuki、Osada-Oka Mayuko、Sano Soichi、Yoshiyama Minoru、Miura Katsuyuki、Kitajima Shojiro、Matsunaga Shinji、Tomita Shuhei、Iwao Hiroshi、Izumi Yasukatsu
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 139 Pages: 112-119
- DOI
  10.1016/j.jphs.2018.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-17K08958, KAKENHI-PROJECT-17K15757, KAKENHI-PROJECT-15K08649
[Journal Article] Tumour blood vessel normalisation by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumour mouse model2017
- Author(s)
  Koyama S, Matsunaga S, Imanishi M, Maekawa Y, Kitano H, Takeuchi H, Tomita S
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 45621-45621
- DOI
  10.1038/srep45621
- NAID
  120006535012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15054, KAKENHI-PROJECT-17K08602, KAKENHI-PROJECT-16K15524, KAKENHI-PROJECT-15H04724
[Journal Article] Hypoxia-inducible factor-1α in smooth muscle cells protects against aortic aneurysms.2016
- Author(s)
  Imanishi M, Chiba Y, Tomita N, Matsunaga S, Nakagawa T, Ueno M, Yamamoto K, Tamaki T, Tomita S
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 36 Pages: 2158-2162
- DOI
  10.1161/atvbaha.116.307784
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15054
[Patent] 抗癌剤の抗腫瘍効果の増強剤、癌治療剤、及び癌治療用医薬組成物2016
- Inventor(s)
  冨田修平・松永慎司
- Industrial Property Rights Holder
  冨田修平・松永慎司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-171299
- Filing Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] PHD阻害薬によるがん微小環境と腫瘍免疫への影響2019
- Author(s)
  松永慎司、冨田修平
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15459
[Presentation] Improvement of tumor microenvironment induce macrophage activation in tumor bearing mouse.2019
- Author(s)
  Shinji Matsunaga, Shunji Nishide, Masayuki Shiota, Takehiro Yamaghchi, Katsuyuki Miura, Shuhei Tomita
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15459
[Presentation] Prolyl Hydroxylase inhibitor repaired chemo-sensitivity through tumor blood vessel normalization in tumor mouse model.2018
- Author(s)
  Shinji Matsunaga, Shunji Nishide, Masayuki Shiota, Takehiro Yamaghchi, Shojiro Kitajima, Katsuyuki Miura, Shuhei Tomita.
- Organizer
  第91回日本薬理学会年会・第18回国際薬理学・臨床薬理会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15459
[Presentation] 薬剤誘導性腫瘍血管正常化は抗癌剤感受性を増強させる2018
- Author(s)
  松永慎司、西出峻治、北島正二朗、山口雄大、塩田正之、三浦克之、冨田修平
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K15459
[Presentation] Hypoxia-inducible factor-1α regulates energy fuel metabolism and mediates metabolic plasticity during ammonia stress response in ovarian cancer stem-like cells.2018
- Author(s)
  Shojiro Kitajima, Kian Leong Lee, Hiroki Hikasa, Shinji Matsunaga, Takehiro Yamaguchi, Shuhei Tomita, Marito Araki, Hiroyuki Kato and Lorenz Poellinger
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July 1-6, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] Prolyl Hydroxylase inhibitor repaired chemo-sensitivity through tumor blood vessel normalization in tumor mouse model.2018
- Author(s)
  Shinji Matsunaga, Shunji Nishide, Masayuki Shiota, Takehiro Yamaghchi, Shojiro Kitajima, Katsuyuki Miura and Shuhei Tomita.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July 1-6, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] 肺血管内皮細胞由来低酸素応答因子 HIF が肺高血圧症の病態形成に果たす役割2018
- Author(s)
  冨田修平，山口雄大，松永慎司
- Organizer
  第47回日本心脈管作動物質学会年会
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] Dipeptidyl Peptidase-4 (DPP-4) inhibition Attenuates Cardiac Dysfunction after Myocardial Infarction Independently of DPP-4.2018
- Author(s)
  Yamaguchi T, Izumi Y, Shiota M, Tanaka M, Osada-Oka M, Matsunaga S, Kitajima S, Miura K, Iwao H, Tomita S
- Organizer
  18th World Congress of Basic and Clinical Pharmacology, July 1-6, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08602
[Presentation] Normalization of tumor blood vessel induced by neovascularization drug.2016
- Author(s)
  松永慎司、小山哲史、井口道代、今西正樹、冨田修平
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜（横浜パシフィコ）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K15054
[Presentation] The effect of antioxidants treatment on Seminal Vesicles and Vas Deferens function in the Diabetes Mellitus rat model.2015
- Author(s)
  Panagiota Tsounapi, Masashi Honda, Shinji Hirano, Bunya Kawamoto, Katsuya Hikita, Kuniyasu Muraoka, Michiyo Iguchi, Masaki Imanishi, Shinji Matsunaga, Shuhei Tomita, Takehiro Sejima, Atsushi Takenaka.
- Organizer
  The 103rd Annual Meeting of the Japanese Urological Association
- Place of Presentation
  Kanazawa(Kanazawa Art Hall（石川県金沢市）)
- Year and Date
  2015-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15054

1. Tomita Shuhei (00263898)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. SHIOTA masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. NISHIDE shunji

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. MIURA Katsuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. YOSHIYAMA Minoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 富田修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 11 results
7. 田中昌子(橘昌子)

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 前川洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsunaga Shinji 松永 慎司

Research Projects

Research Products

Co-Researchers

腫瘍微小環境改善薬による抗腫瘍免疫応答制御機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research of cancer therapy by improving anticancer drug sensitivity through tumor vascular remodeling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effects of PHD inhibitor on tumor blood vessel normalizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tumor blood vessel normalization by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumor mouse model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 尿酸と血糖「第5回忙しい人のための抄読会」2016

Author(s)

Total Pages

Publisher

Data Source

[Book] 医学のあゆみ（別冊）レドックスUPDATE「血管リモデリングにおける低酸素応答性転写因子の役割」2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumour blood vessel normalisation by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumour mouse model2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Hypoxia-inducible factor-1α in smooth muscle cells protects against aortic aneurysms.2016

Author(s)

Journal Title

DOI

Data Source

[Patent] 抗癌剤の抗腫瘍効果の増強剤、癌治療剤、及び癌治療用医薬組成物2016

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] PHD阻害薬によるがん微小環境と腫瘍免疫への影響2019

Author(s)

Organizer

Data Source

[Presentation] Improvement of tumor microenvironment induce macrophage activation in tumor bearing mouse.2019

Author(s)

Organizer

Data Source

[Presentation] Prolyl Hydroxylase inhibitor repaired chemo-sensitivity through tumor blood vessel normalization in tumor mouse model.2018

Author(s)

Organizer

Data Source

[Presentation] 薬剤誘導性腫瘍血管正常化は抗癌剤感受性を増強させる2018

Author(s)

Organizer

Data Source

[Presentation] Hypoxia-inducible factor-1&alpha; regulates energy fuel metabolism and mediates metabolic plasticity during ammonia stress response in ovarian cancer stem-like cells.2018

Author(s)

Organizer

Matsunaga Shinji 松永慎司

[Presentation] Hypoxia-inducible factor-1α regulates energy fuel metabolism and mediates metabolic plasticity during ammonia stress response in ovarian cancer stem-like cells.2018

[Presentation] 肺血管内皮細胞由来低酸素応答因子 HIF が肺高血圧症の病態形成に果たす役割2018