Noda Shuhei 野田修平

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NODA Shuhei 野田修平

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Researcher Number	30710131
Other IDs	https://orcid.org/0000-0001-5430-1966
Affiliation (Current)	2026: 立命館大学, 総合科学技術研究機構, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 神戸大学, 科学技術イノベーション研究科, 特命准教授 2018 – 2022: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員 2017: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 基礎科学特別研究員 2013 – 2014: 独立行政法人理化学研究所, 環境資源科学研究センター, 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related / Transformative Research Areas, Section (II) / Biofunction/Bioprocess
Keywords	Principal Investigator 大腸菌 / メタノール / 機械学習 / 代謝工学 / 増殖制御 / 微生物進化 / バイオ生産 / 進化実験 / 代謝デザイン / アセチル-CoA合成経路 … More / フェニルプロパノイド / 3-ヒドロキシキヌレニンC-メチル転移酵素 / 酸化還元酵素 / C1増炭反応 / S-アデノシルメチオニン転移酵素 / 芳香環 / in silico酵素開発 / S-アデノシルメチオニン / 遺伝子発現量解析 / プラットホーム / プラスミド構成要素 / 遺伝子発現パターン / 遺伝子発現 / プラスミドライブラリィ / 遺伝子導入 / 主成分分析 / 薬剤耐性 / 複製開始起点 / プラスミド / フェニル乳酸 / 酵素ホモロージーモデリング / 酵素工学 / 酵素ホモロジーモデル / 新規酵素 / ムコン酸 / マレイン酸 / cis, cis-ムコン酸 / 酵素改変 / アジピン酸 / バイオテクノロジー / 応用微生物 / 発酵 / ピルビン酸 / Escherichia coli / 合成生物学 / 芳香族化合物 / Saccharomyces cerevisiae / Tyrosine decarboxylase / アセチル-CoA / NADPH / Kluyveromyces lactis Less

CO世界で進化する合成微生物Principal Investigator
- Principal Investigator
  
  野田修平
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Kobe University
階層間ネットワークの理解が拓く理想的バイオ生産基盤Principal Investigator
- Principal Investigator
  
  野田修平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kobe University
Method for the optimal plasmid selection to produce chemical compounds using Escherichia coliPrincipal Investigator
- Principal Investigator
  
  Shuhei Noda
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kobe University
炭素をつなぐ：SAMT自在制御基盤の確立Principal Investigator
- Principal Investigator
  
  野田修平
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Kobe University
Aromatic Compound Synthesis Platform by Rational Design of Novel EnzymesPrincipal Investigator
- Principal Investigator
  
  Noda Shuhei
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Institute of Physical and Chemical Research
Development of aromatic compounds synthesis platform extending pyruvate bypass/recycling systemPrincipal Investigator
- Principal Investigator
  
  Noda Shuhei
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Institute of Physical and Chemical Research
Development of the tailor-made biosynthesis system of aromatic compounds using microbePrincipal Investigator
- Principal Investigator
  
  NODA Shuhei
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The Institute of Physical and Chemical Research

All 2025 2024 2023 2022 2019 2018 2017 2015 2014 Other

All Journal Article Presentation Patent

[Journal Article] Modular pathway engineering for enhanced production of para -aminobenzoic acid and 4-amino-phenylalanine in Escherichia coli via glucose/xylose co-utilization2025
- Author(s)
 Nonaka Daisuke、Kishida Mayumi、Hirata Yuuki、Mori Ayana、Kondo Akihiko、Mori Yutaro、Noda Shuhei、Tanaka Tsutomu
- Journal Title
 
 Applied and Environmental Microbiology
 
 Volume: - Issue: 5
- DOI
 10.1128/aem.02468-24
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PUBLICLY-23H04565, KAKENHI-PROJECT-23K23148, KAKENHI-PROJECT-23K23153, KAKENHI-PROJECT-22KJ2279
[Journal Article] Metabolic Engineering for Resveratrol Production Based on Modularization of Metabolic Pathways in Escherichia coli2025
- Author(s)
 Nonaka Daisuke、Kishida Mayumi、Hirata Yuuki、Mori Ayana、Kondo Akihiko、Mori Yutaro、Noda Shuhei、Tanaka Tsutomu
- Journal Title
 
 Journal of Agricultural and Food Chemistry
 
 Volume: - Issue: 19 Pages: 11878-11888
- DOI
 10.1021/acs.jafc.5c00804
- Peer Reviewed
- Data Source
 KAKENHI-PUBLICLY-23H04565, KAKENHI-PROJECT-23K23148, KAKENHI-PROJECT-23K23153, KAKENHI-PROJECT-22KJ2279
[Journal Article] Metabolic engineering of Escherichia coli for 4-nitrophenylalanine production via the 4-aminophenylalanine synthetic pathway2025
- Author(s)
  Mori Ayana、Hirata Yuuki、Kishida Mayumi、Nonaka Daisuke、Kondo Akihiko、Mori Yutaro、Noda Shuhei、Tanaka Tsutomu
- Journal Title
  
  Metabolic Engineering
  
  Volume: 91 Pages: 171-180
- DOI
  10.1016/j.ymben.2025.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04565, KAKENHI-PROJECT-23K23148, KAKENHI-PROJECT-23K23153
[Journal Article] Metabolic and enzymatic engineering approach for the production of 2-phenylethanol in engineered Escherichia coli.2024
- Author(s)
  Shuhei Noda, Yutaro Mori, Yuki Ogawa, Ryosuke Fujiwara, Mayumi Dainin, Tomokazu Shirai, Akihiko Kondo
- Journal Title
  
  Bioresource Technology
  
  Volume: 406 Pages: 130927-130927
- DOI
  10.1016/j.biortech.2024.130927
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05230, KAKENHI-PUBLICLY-23H04565, KAKENHI-PROJECT-23H05473, KAKENHI-PROJECT-23K23153, KAKENHI-PROJECT-24K17572
[Journal Article] Styrene Production in Genetically Engineered Escherichia coli in a Two-Phase Culture2024
- Author(s)
  Noda Shuhei、Fujiwara Ryosuke、Mori Yutaro、Dainin Mayumi、Shirai Tomokazu、Kondo Akihiko
- Journal Title
  
  BioTech
  
  Volume: 13 Issue: 1 Pages: 2-2
- DOI
  10.3390/biotech13010002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14777, KAKENHI-PUBLICLY-23H04565, KAKENHI-PROJECT-23K23153, KAKENHI-PROJECT-23H05473
[Journal Article] Parallel metabolic pathway engineering for aerobic 1,2‐propanediol production in Escherichia coli2024
- Author(s)
 Nonaka Daisuke、Hirata Yuuki、Kishida Mayumi、Mori Ayana、Fujiwara Ryosuke、Kondo Akihiko、Mori Yutaro、Noda Shuhei、Tanaka Tsutomu
- Journal Title
 
 Biotechnology Journal
 
 Volume: 19 Issue: 8
- DOI
 10.1002/biot.202400210
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PUBLICLY-23H04565, KAKENHI-PROJECT-23K23148, KAKENHI-PROJECT-23K23153, KAKENHI-PROJECT-22KJ2279, KAKENHI-PROJECT-24K17572
[Journal Article] Hydroxybenzoic Acid Production Using Metabolically Engineered Corynebacterium glutamicum2023
- Author(s)
  2.Doke M, Kishida M, Hirata Y, Nakano M, Horita M, Nonaka D, Mori Y, Fujiwara R, Kondo A, Noda S, Tanaka T
- Journal Title
  
  Synth Biol Eng
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23153
[Journal Article] Caffeic acid production from glucose using metabolically engineered Escherichia coli2023
- Author(s)
  Sakae Kosuke、Nonaka Daisuke、Kishida Mayumi、Hirata Yuuki、Fujiwara Ryosuke、Kondo Akihiko、Noda Shuhei、Tanaka Tsutomu
- Journal Title
  
  Enzyme and Microbial Technology
  
  Volume: 164 Pages: 110193-110193
- DOI
  10.1016/j.enzmictec.2023.110193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K14777, KAKENHI-PROJECT-20H00321, KAKENHI-PROJECT-22KJ2279, KAKENHI-PROJECT-20K22574, KAKENHI-PROJECT-23K23148, KAKENHI-PROJECT-23K23153
[Journal Article] Investigation of two metabolic engineering approaches for (R,R)-2,3-butanediol production from glycerol in Bacillus subtilis2023
- Author(s)
  Vikromvarasiri Nunthaphan、Noda Shuhei、Shirai Tomokazu、Kondo Akihiko
- Journal Title
  
  Journal of Biological Engineering
  
  Volume: 17 Issue: 1 Pages: 3-13
- DOI
  10.1186/s13036-022-00320-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23153, KAKENHI-PLANNED-21H05230, KAKENHI-PROJECT-23H05473
[Journal Article] G6P-capturing molecules in the periplasm of Escherichia coli accelerate the shikimate pathway2022
- Author(s)
  Fujiwara, R., Nakano, M., Hirata, Y., Otomo, C., Nonaka, D., Kawada, S., Nakazawa, H., Umetsu, M., Shirai, T., Noda, S.*, Tanaka, T.*, Kondo, A.
- Journal Title
  
  Metabolic Engineering
  
  Volume: 72 Pages: 68-81
- DOI
  10.1016/j.ymben.2022.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02526, KAKENHI-PROJECT-21K14777, KAKENHI-PROJECT-20H00321, KAKENHI-PROJECT-22KJ2279, KAKENHI-PROJECT-19K15370, KAKENHI-PROJECT-20K22574, KAKENHI-PROJECT-23K23148, KAKENHI-PROJECT-23K23153
[Journal Article] Engineering a synthetic pathway for maleate in Escherichia coli2017
- Author(s)
  Noda S, Shirai T, Mori Y, Oyama S, Kondo A
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 1153-1165
- DOI
  10.1038/s41467-017-01233-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14870
[Journal Article] Recent Advances in Microbial Production of Aromatic Chemicals and Derivatives2017
- Author(s)
  Noda S, Kondo A
- Journal Title
  
  Trends Biotechnol
  
  Volume: 35 Issue: 8 Pages: 785-796
- DOI
  10.1016/j.tibtech.2017.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14870
[Journal Article] Evaluation of Brachypodium distachyon L-Tyrosine Decarboxylase Using L-Tyrosine Over-Producing Saccharomyces cerevisiae2015
- Author(s)
  Shuhei Noda, Tomokazu Shirai, Keiichi Mochida, Fumio Matsuda, Sachiko, Oyama, Mami Okamoto, Akihiko Kondo
- Journal Title
  
  PLoS ONE
  
  Volume: - Issue: 5 Pages: e0125488-e0125488
- DOI
  10.1371/journal.pone.0125488
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25889071
[Patent] サリチル酸の製造方法2014
- Inventor(s)
  野田修平、白井智量
- Industrial Property Rights Holder
  野田修平、白井智量
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-25889071
[Presentation] 大腸菌を用いた芳香族化合物生産及びポリマー生産への拡張2024
- Author(s)
  野田修平
- Organizer
  第92回酵素工学研究会
- Data Source
  KAKENHI-PROJECT-23K23153
[Presentation] Metabolic and enzymatic engineering approach for the production and degradation of biopolymer2024
- Author(s)
  Noda S, Koh S, Katano A, Nonaka D, Mori Y, Fujiwara R, Shirai T, Tanaka T, Taguchi S, Kondo A
- Organizer
  13th International Conference on Biomedical Engineering and Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23153
[Presentation] Metabolic and enzymatic engineering approach for the aromatic chemical production in Escherichia coli2024
- Author(s)
  Noda S, Ogawa Y, Mori Y, Fujiwara R, Shirai T, Tanaka T, Kondo A
- Organizer
  15th International Conference on Bioscience, Biochemistry and Bioinformatics
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04565
[Presentation] 大腸菌を用いた芳香族化合物生産及びポリマー生産への拡張2024
- Author(s)
  野田修平
- Organizer
  第92回酵素工学研究会
- Data Source
  KAKENHI-PUBLICLY-23H04565
[Presentation] Metabolic and enzymatic engineering approach for the aromatic chemical production in Escherichia coli2024
- Author(s)
  Noda S, Ogawa Y, Mori Y, Fujiwara R, Shirai T, Tanaka T, Kondo A
- Organizer
  15th International Conference on Bioscience, Biochemistry and Bioinformatics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23153
[Presentation] Metabolic and enzymatic engineering approach for the production and degradation of biopolymer2024
- Author(s)
  Noda S, Koh S, Katano A, Nonaka D, Mori Y, Fujiwara R, Shirai T, Tanaka T, Taguchi S, Kondo A
- Organizer
  13th International Conference on Biomedical Engineering and Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04565
[Presentation] Metabolic Engineering of Escherichia coli for the Production and Degradation of Microbial-Polymer2023
- Author(s)
  Shuhei Noda1,2*, Sangho Koh1, Akinobu Katano3, Daisuke Nonaka3, Yutaro Mori3, Ryosuke Fujiwara, Tomokazu Shirai, Tsutomu Tanaka, Seiichi Taguchi, Akihiko Kondo
- Organizer
  16th Asian Congress on Biotechnology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23153
[Presentation] 有用バルクケミカル合成大腸菌プラットホーム開発における質量分析機器の活用2019
- Author(s)
  野田修平
- Organizer
  質量分析インフォマティクス研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K14870
[Presentation] 芳香族化合物合成プラットホームの開発～芳香族モノマー合成に理想的な大腸菌代謝デザイン～2018
- Author(s)
  野田修平
- Organizer
  生物工学会
- Data Source
  KAKENHI-PROJECT-17K14870
[Presentation] Microbial platform to synthesize aromatic chemicals and the derivatives2018
- Author(s)
  Shuhei Noda
- Organizer
  FEBS2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14870
[Presentation] 大腸菌を用いた芳香族化合物誘導体合成プラットホームの開発2017
- Author(s)
  野田修平、白井智量、近藤昭彦
- Organizer
  酵素工学研究会　第78回講演会
- Data Source
  KAKENHI-PROJECT-17K14870
[Presentation] Metabolic engineering of Escherichia coli for maleate production via chorismate pathway2017
- Author(s)
  Shuhei Noda, Tomokazu Shirai, Akihiko Kondo
- Organizer
  SB7.0: The Seventh International Meeting on Synthetic Biology
- Data Source
  KAKENHI-PROJECT-17K14870
[Presentation] Microbial platform to synthesize chorismate derivatives via metabolic engineering approach2017
- Author(s)
  Shuhei Noda, Tomokazu Shirai, Akihiko Kondo
- Organizer
  Enzyme Engineering XXIV
- Data Source
  KAKENHI-PROJECT-17K14870
[Presentation] Metabolic engineering of the yeast Saccharomyces cerevisiae to enhance tyramine production
- Author(s)
  Shuhei Noda
- Organizer
  Biocat2014
- Place of Presentation
  Hamburg university of technology, Hamburg, Germany
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25889071
[Presentation] 草本系モデル植物ブラキポディウム由来芳香族脱炭酸酵素を用いた酵母によるチラミン合成
- Author(s)
  野田修平
- Organizer
  生物工学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-09 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-25889071
[Presentation] チロシン合成経路におけるフィードバック阻害を解除した酵母を用いたチロシン誘導体生合成
- Author(s)
  野田修平
- Organizer
  化学工学会秋季大会
- Place of Presentation
  九州大学（福岡県福岡市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25889071

1. 荒木通啓 (40396867)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 白井智量 (00639586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. TANAKA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 藤原良介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Noda Shuhei 野田 修平

NODA Shuhei 野田 修平

Research Projects

Research Products

Co-Researchers

CO世界で進化する合成微生物Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

階層間ネットワークの理解が拓く理想的バイオ生産基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Method for the optimal plasmid selection to produce chemical compounds using Escherichia coliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

炭素をつなぐ：SAMT自在制御基盤の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Aromatic Compound Synthesis Platform by Rational Design of Novel EnzymesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of aromatic compounds synthesis platform extending pyruvate bypass/recycling systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the tailor-made biosynthesis system of aromatic compounds using microbePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Modular pathway engineering for enhanced production of <i>para</i> -aminobenzoic acid and 4-amino-phenylalanine in <i>Escherichia coli</i> via glucose/xylose co-utilization2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic Engineering for Resveratrol Production Based on Modularization of Metabolic Pathways in <i>Escherichia coli</i>2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic engineering of Escherichia coli for 4-nitrophenylalanine production via the 4-aminophenylalanine synthetic pathway2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic and enzymatic engineering approach for the production of 2-phenylethanol in engineered Escherichia coli.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Styrene Production in Genetically Engineered Escherichia coli in a Two-Phase Culture2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Parallel metabolic pathway engineering for aerobic 1,2‐propanediol production in <i>Escherichia coli</i>2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydroxybenzoic Acid Production Using Metabolically Engineered Corynebacterium glutamicum2023

Author(s)

Journal Title

Noda Shuhei 野田修平

NODA Shuhei 野田修平