TAKAZONO Takahiro 高園貴弘

… Alternative Names

Takazono Takahiro 高園貴弘

高園貴弘タカゾノタカヒロ

Less

Researcher Number	30716569
Other IDs
External Links
Affiliation (Current)	2023: 長崎大学, 医歯薬学総合研究科(医学系), 准教授
Affiliation (based on the past Project Information) *help	2023: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2021: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2018 – 2020: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2014 – 2015: 長崎大学, 医歯薬学総合研究科(医学系), 助教
Review Section/Research Field	Principal Investigator Infectious disease medicine / Basic Section 49050:Bacteriology-related / Basic Section 54030:Infectious disease medicine-related Except Principal Investigator Basic Section 54030:Infectious disease medicine-related / Infectious disease medicine
Keywords	Principal Investigator 感染症 / 慢性肺アスペルギルス症 / Biofilm / バイオフィルム / カンジダ / PslG / カテーテル感染症 / アスペルギルス症 / 自然免疫系エフェクター細胞 / γ9δ2 型 T 細胞 / NK細胞 … More Except Principal Investigator … More アスペルギルス / 薬剤耐性 / 病原性 / 吸入治療 / MUC5AC / マクロライド / CYP51A / カルシニューリン / 非結核性抗酸菌 / 細胞間コミュニケーション / 病原細菌 / 微生物間インタラクション解析 / 重複感染 Less

アスペルギルスと細菌の微生物間インタラクション解析による重複感染病態の解明と制御
- Principal Investigator
  
  泉川公一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nagasaki University
Development of a new treatment strategy for pulmonary aspergillosis by innate immune effector cellsPrincipal Investigator
- Principal Investigator
  
  高園貴弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nagasaki University
アスペルギルスと非結核性抗酸菌の細胞間コミュニケーションを介した難治化機序の解明
- Principal Investigator
  
  泉川公一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nagasaki University
Development of New strategy for Candida biofilm infection by hydrolase PslGPrincipal Investigator
- Principal Investigator
  
  Takazono Takahiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Nagasaki University
慢性肺アスペルギルス症発症に関与する新規病原因子の検索Principal Investigator
- Principal Investigator
  
  高園貴弘
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagasaki University
Discovery of drug-resistant mechanism and development of new treatment strategy by modulating virulence factors against drug-resistant Aspergillus infection
- Principal Investigator
  
  IZUMIKAWA Koichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagasaki University

All 2021 2020 2019 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 分子呼吸器病2014
- Author(s)
  高園隆弘、泉川公一
- Total Pages
  176
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-25461515
[Journal Article] Clinical and experimental phenotype of azole-resistant Aspergillus fumigatus with a HapE splice site mutation: a case report2021
- Author(s)
  Ito Yuya、Takazono Takahiro、Koga Satoru、Nakano Yuichiro、Ashizawa Nobuyuki、Hirayama Tatsuro、Tashiro Masato、Saijo Tomomi、Yamamoto Kazuko、Imamura Yoshifumi、Miyazaki Taiga、Yanagihara Katsunori、Izumikawa Koichi、Mukae Hiroshi
- Journal Title
  
  BMC Infectious Diseases
  
  Volume: 21 Issue: 1 Pages: 573-573
- DOI
  10.1186/s12879-021-06279-1
- NAID
  120007168844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08840
[Journal Article] Transition of triazole-resistant Aspergillus fumigatus isolates in a Japanese tertiary hospital and subsequent genetic analysis2021
- Author(s)
  Takazono Takahiro、Ito Yuya、Tashiro Masato、Nakano Yuichiro、Hirayama Tatsuro、Hosogaya Naoki、Saijo Tomomi、Yamamoto Kazuko、Imamura Yoshifumi、Miyazaki Taiga、Yanagihara Katsunori、Kohno Shigeru、Mukae Hiroshi、Izumikawa Koichi
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 27 Issue: 3 Pages: 537-539
- DOI
  10.1016/j.jiac.2020.11.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08840
[Journal Article] COVID-19 associated pulmonary aspergillosis: a nationwide survey by the Japanese Respiratory Society2021
- Author(s)
  Takazono Takahiro、Mukae Hiroshi、Izumikawa Koichi、Hasegawa Naoki、Yokoyama Akihito
- Journal Title
  
  ERJ Open Research
  
  Volume: 7 Issue: 4 Pages: 1-4
- DOI
  10.1183/23120541.00402-2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08840
[Journal Article] Detection of invasive pulmonary aspergillosis in mice using lung perfusion single-photon emission computed tomography with [99mTc]MAA2020
- Author(s)
  Yoshida Masataka、Tashiro Masato、Nishi Kodai、Mishima Maki、Kawano Kei、Takazono Takahiro、Saijo Tomomi、Yamamoto Kazuko、Imamura Yoshifumi、Miyazaki Taiga、Kudo Takashi、Yanagihara Katsunori、Mukae Hiroshi、Izumikawa Koichi
- Journal Title
  
  Medical Mycology
  
  Volume: - Issue: 7 Pages: 965-972
- DOI
  10.1093/mmy/myz131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10447, KAKENHI-PROJECT-20K08053, KAKENHI-PROJECT-20K08840
[Journal Article] Characteristics of azole-resistant Aspergillus fumigatus attached to agricultural products imported to Japan2020
- Author(s)
  Nakano Yuichiro、Tashiro Masato、Urano Ryo、Kikuchi Minori、Ito Naoki、Moriya Eriko、Shirahige Tomoyuki、Mishima Maki、Takazono Takahiro、Miyazaki Taiga、Izumikawa Koichi
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 26 Issue: 10 Pages: 1021-1025
- DOI
  10.1016/j.jiac.2020.05.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08840
[Journal Article] Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection2020
- Author(s)
  Snarr Brendan D.、St-Pierre Guillaume、Takazono Takahiro、Sugrue Michele、Baden Lindsey R.、Izumikawa Koichi、Mukae Hiroshi、Wingard John R.、King Irah L.、Divangahi Maziar、Satoh Masahiko S.、Yipp Bryan G.、Sato Sachiko、Sheppard Donald C.
- Journal Title
  
  PLOS Pathogens
  
  Volume: 16 Issue: 8 Pages: 1008741-008741
- DOI
  10.1371/journal.ppat.1008741
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08840
[Journal Article] A mortality prediction rule for non-elderly patients with community-acquired pneumonia.2016
- Author(s)
  Tashiro M, Fushimi K, Takazono T, Kurihara S, Miyazaki T, Tsukamoto M, Yanagihara K, Mukae H, Tashiro T, Kohno S, Izumikawa K.
- Journal Title
  
  BMC Pulm Med
  
  Volume: 16 Issue: 1 Pages: 39-39
- DOI
  10.1186/s12890-016-0199-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461515, KAKENHI-PROJECT-16K09936
[Journal Article] The risk factors for developing of chronic pulmonary aspergillosis in nontuberculous mycobacteria patients and clinical characteristics and outcomes in chronic pulmonary aspergillosis patients coinfected with nontuberculous mycobacteria.2016
- Author(s)
  Takeda K, Imamura Y, Takazono T, Yoshida M, Ide S, Hirano K, Tashiro M, Saijo T, Kosai K, Morinaga Y, Nakamura S, Kurihara S, Tsukamoto M, Miyazaki T, Tashiro T, Kohno S, Yanagihara K, Izumikawa K.
- Journal Title
  
  Med Mycol.
  
  Volume: 54 Issue: 2 Pages: 120-127
- DOI
  10.1093/mmy/myv093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09573, KAKENHI-PROJECT-25461515, KAKENHI-PROJECT-16K09936
[Journal Article] Clinical characteristics and risk factors of enterococcal infections in Nagasaki, Japan: a retrospective study.2015
- Author(s)
  Kajihara T, Nakamura S, Iwanaga N, Oshima K, Takazono T, Miyazaki T, Izumikawa K, Yanagihara K, Kohno N, Kohno S.
- Journal Title
  
  BMC Infect Dis
  
  Volume: 15 Issue: 1 Pages: 426-426
- DOI
  10.1186/s12879-015-1175-6
- NAID
  120006986848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461515
[Journal Article] Macrolides promote CCL2-mediated macrophage recruitment and clearance of nasopharyngeal pneumococcal colonies in mice.2015
- Author(s)
  Naoki Iwanaga, Shigeki Nakamura, Kazuhiro Oshima, Toshiki Kajihara, Takahiro Takazono, Taiga Miyazaki, Koichi Izumikawa, Katsunori Yanagihara, Akihiro Sugawara, Toshiaki Sunazuka, Satoshi Omura and Shigeru Kohno
- Journal Title
  
  J. Infect. Dis.
  
  Volume: - Issue: 7 Pages: 1150-1159
- DOI
  10.1093/infdis/jiv157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26102737, KAKENHI-PROJECT-15K09573, KAKENHI-PROJECT-25461515
[Journal Article] Macrolides Promote CCL2-Mediated Macrophage Recruitment and Clearance of Nasopharyngeal Pneumococcal Colonization in Mice.2015
- Author(s)
  Iwanaga N, Nakamura S, Oshima K, Kajihara T, Takazono T, Miyazaki T, Izumikawa K, Yanagihara K, Sugawara A, Sunazuka T, Omura S, Kohno S.
- Journal Title
  
  J Infect Dis.
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860770
[Journal Article] Importance of functional assessment in the management of community-acquired and healthcare-associated pneumonia.2014
- Author(s)
  Kosai K, Izumikawa K, Imamura Y, Tanaka H, Tsukamoto M, Kurihara S, Takazono T, Morinaga Y, Nakamura S, Miyazaki T, Yanagihara K, Tashiro T, Kohno S.
- Journal Title
  
  Intern Med.
  
  Volume: 53(15) Pages: 1613-1620
- NAID
  130004678379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860770
[Journal Article] Contribution of the Slt2-regulated transcription factors to echinocandin tolerance in Candida glabrata.2014
- Author(s)
  Nagayoshi Y, Miyazaki T, Minematsu A, Yamauchi S, Takazono T, Nakamura S, Imamura Y, Izumikawa K, Kakeya H, Yanagihara K, Kohno S.
- Journal Title
  
  FEMS Yeast Research
  
  Volume: 14 Pages: 1128-1131
- DOI
  10.1111/1567-1364.12204
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791027, KAKENHI-PROJECT-26860770
[Journal Article] Concurrent subcutaneous candidal abscesses and pulmonary cryptococcosis in a patient with diabetes mellitus and a history of corticosteroid therapy.2014
- Author(s)
  Kakeya H, Izumikawa K, Yamada K, Narita Y, Nishino T, Obata Y, Takazono T, Kurihara S, Kosai K, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Takenaka M, Tashiro T, Kohno S.
- Journal Title
  
  Intern Med.
  
  Volume: 53(12) Pages: 1385-1390
- NAID
  130004466351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860770
[Journal Article] A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients.2014
- Author(s)
  Takazono T, Nakamura S, Imamura Y, Yoshioka S, Miyazaki T, Izumikawa K, Sawai T, Matsuo N, Yanagihara K, Suyama N, Kohno S.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 20(8) Issue: 8 Pages: 484-488
- DOI
  10.1016/j.jiac.2014.04.010
- NAID
  120006987099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860770
[Journal Article] Cavitary pulmonary metastases and aspergillosis: an autopsy case.2013
- Author(s)
  Takazono T, Izumikawa K et al.
- Journal Title
  
  Intern Med
  
  Volume: 52 Pages: 1751-1752
- NAID
  130003365739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461515
[Presentation] カンジダバイオフィルム感染症に対する新規治療法の開発2019
- Author(s)
  高園貴弘
- Organizer
  第67回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-18K15148
[Presentation] カンジダバイオフィルムに対する加水分解酵素PslGの阻害効果2019
- Author(s)
  高園貴弘
- Organizer
  第33回日本バイオフィルム学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15148
[Presentation] The burden of serious fungal diseases in Japan2016
- Author(s)
  Izumikawa K, Tashiro M, Takazono T, Kurihara S, Saijo T, Yamamoto K, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Mukae H, Kohno S, Denning DW.
- Organizer
  7th Advances in Aspergillus and Aspergillosis
- Place of Presentation
  マンチェスター(英国）
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461515
[Presentation] Selection of antifungals for initial maintenance therapy of chronic pulmonary aspergillosis: a longitudinal analysis2016
- Author(s)
  Tashiro M, Takazono T, Saijo T, Yamamoto K, Imamura Y, Miyazaki T, Kakeya H, Ando T, Ogawa K, Kishi K, Tokimatsu I, Hayashi Y, Fujiuchi S, Yanagihara K, Ichihara K, Kohno S, Izumikawa K.
- Organizer
  7th Advances in Aspergillus and Aspergillosis
- Place of Presentation
  マンチェスター(英国）
- Year and Date
  2016-02-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461515
[Presentation] アスペルギルスの定着と感染
- Author(s)
  高園貴弘
- Organizer
  日本医真菌学会
- Place of Presentation
  ワークピア横浜（神奈川県横浜市）
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26860770

1. IZUMIKAWA Koichi (20404212)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. 田代将人 (20713457)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. 田中健之 (30432967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 角田俊之 (70444817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 串間尚子 (90642497)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MIYAZAKI Taiga (60448496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 柿内聡志 (40794516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中義正 (90280700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HIRANO Katsuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YOSHIDA Masataka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKEDA Kazuaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUGAWARA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 工藤崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 西弘大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAZONO Takahiro 高園 貴弘

Takazono Takahiro 高園 貴弘

高園 貴弘 タカゾノ タカヒロ

Research Projects

Research Products

Co-Researchers

アスペルギルスと細菌の微生物間インタラクション解析による重複感染病態の解明と制御

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new treatment strategy for pulmonary aspergillosis by innate immune effector cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アスペルギルスと非結核性抗酸菌の細胞間コミュニケーションを介した難治化機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of New strategy for Candida biofilm infection by hydrolase PslGPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

慢性肺アスペルギルス症発症に関与する新規病原因子の検索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discovery of drug-resistant mechanism and development of new treatment strategy by modulating virulence factors against drug-resistant Aspergillus infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 分子呼吸器病2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Clinical and experimental phenotype of azole-resistant Aspergillus fumigatus with a HapE splice site mutation: a case report2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Transition of triazole-resistant Aspergillus fumigatus isolates in a Japanese tertiary hospital and subsequent genetic analysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] COVID-19 associated pulmonary aspergillosis: a nationwide survey by the Japanese Respiratory Society2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of invasive pulmonary aspergillosis in mice using lung perfusion single-photon emission computed tomography with [99mTc]MAA2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristics of azole-resistant Aspergillus fumigatus attached to agricultural products imported to Japan2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A mortality prediction rule for non-elderly patients with community-acquired pneumonia.2016

Author(s)

TAKAZONO Takahiro 高園貴弘

Takazono Takahiro 高園貴弘

高園貴弘タカゾノタカヒロ