Horinouchi Yuya 堀ノ内裕也

… Alternative Names

HORINOUCHI Yuya 堀ノ内裕也

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Researcher Number	30716593
Other IDs
Affiliation (Current)	2025: 徳島文理大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 徳島文理大学, 薬学部, 准教授 2020 – 2023: 徳島文理大学, 薬学部, 講師 2018 – 2021: 徳島大学, 大学院医歯薬学研究部(医学域), 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Applied health science Except Principal Investigator Basic Section 48030:Pharmacology-related / Applied health science
Keywords	Principal Investigator 慢性腎臓病 / 医療ビッグデータ / 慢性腎障害 / 急性腎障害 / FAERS / 加齢・老化 / 鉄代謝異常 / 鉄 / サルコペニア / 慢性腎不全 … More Except Principal Investigator … More 転移 / 腫瘍血管 / 医療ビッグデータ / 担がんモデルマウス / 内皮間葉転換 / がん / 血管内皮細胞 / ERK5 / ユビキチンリガーゼ / 骨格筋萎縮 / 骨格筋 / 酸化ストレス / サルコペニア / 鉄 Less

トランスレーショナルリサーチを志向した慢性腎臓病の新たな薬物療法の基盤確立Principal Investigator
- Principal Investigator
  
  堀ノ内裕也
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokushima Bunri University
ビッグデータ解析と基礎研究を融合した慢性腎臓病の機序解明と新しい治療戦略開発Principal Investigator
- Principal Investigator
  
  堀ノ内裕也
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokushima Bunri University
Elucidation of the role of ERK5 and the mechanism of epithelial-mesenchymal transition for cancer metastasis control
- Principal Investigator
  
  IZAWA-ISHIZAWA Yuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  The University of Tokushima
Development of new treatment strategy for chronic kidney disease using medical big dataPrincipal Investigator
- Principal Investigator
  
  HORINOUCHI YUYA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokushima Bunri University
  The University of Tokushima
Molecular mechanism elucidation of iron metabolism abnormality and sarcopenia onset in chronic renal failurePrincipal Investigator
- Principal Investigator
  
  HORINOUCHI Yuya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  The University of Tokushima
The role of iron on sarcopenia, and the therapeutic significance of iron regulation for anti-sarcopenia
- Principal Investigator
  
  IKEDA Yasumasa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  The University of Tokushima

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Pemafibrate inhibited renal dysfunction and fibrosis in a mouse model of adenine-induced chronic kidney disease2023
- Author(s)
  Horinouchi Yuya、Murashima Yuka、Yamada Yuto、Yoshioka Shun、Fukushima Keijo、Kure Takumi、Sasaki Naofumi、Imanishi Masaki、Fujino Hiromichi、Tsuchiya Koichiro、Shinomiya Kazuaki、Ikeda Yasumasa
- Journal Title
  
  Life Sciences
  
  Volume: 321 Pages: 121590-121590
- DOI
  10.1016/j.lfs.2023.121590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06682, KAKENHI-PROJECT-22K15293, KAKENHI-PROJECT-21K07914
[Journal Article] Examination of the antiepileptic effects of valacyclovir using kindling mice― search for novel antiepileptic agents by drug repositioning using a large medical information database2021
- Author(s)
  Takahashi Shimon、Takechi Kenshi、Jozukuri Natsumi、Niimura Takahiro、Chuma Masayuki、Goda Mitsuhiro、Zamami Yoshito、Izawa-Ishizawa Yuki、Imanishi Masaki、Horinouchi Yuya、Ikeda Yasumasa、Tsuchiya Koichiro、Yanagawa Hiroaki、Ishizawa Keisuke
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 902 Pages: 174099-174099
- DOI
  10.1016/j.ejphar.2021.174099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16448, KAKENHI-PROJECT-19K07321, KAKENHI-PLANNED-20H05798, KAKENHI-PLANNED-20H05799, KAKENHI-PROJECT-21H02646, KAKENHI-PROJECT-20K07132, KAKENHI-PROJECT-21K06682, KAKENHI-PROJECT-21K07914
[Journal Article] Role of ferroptosis in cisplatin-induced acute nephrotoxicity in mice.2021
- Author(s)
  Ikeda Y, Hamano H, Horinouchi Y, Miyamoto L, Hirayama T, Nagasawa H, Tamaki T, Tsuchiya K.
- Journal Title
  
  J Trace Elem Med Biol.
  
  Volume: 67 Pages: 126798-126798
- DOI
  10.1016/j.jtemb.2021.126798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17285, KAKENHI-PROJECT-21K06682, KAKENHI-PROJECT-21K07914
[Journal Article] Diphenhydramine may be a preventive medicine against cisplatin-induced kidney toxicity2021
- Author(s)
  Hamano H, Ikeda Y, Goda M, Fukushima K, Kishi S, Chuma M, Yamashita M, Niimura T, Takechi K, Imanishi M, Zamami Y, Horinouchi Y, Izawa-Ishizawa Y, Miyamoto L, Ishizawa K, Fujino H, Tamaki T, Aihara KI,
- Journal Title
  
  Kidney International
  
  Volume: 99 Issue: 4 Pages: 885-899
- DOI
  10.1016/j.kint.2020.10.041
- NAID
  120007175668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-19K07321, KAKENHI-PROJECT-20K07132, KAKENHI-PROJECT-19K16374, KAKENHI-PROJECT-20K17285, KAKENHI-PLANNED-20H05799, KAKENHI-PROJECT-19J11675, KAKENHI-PROJECT-19K16448, KAKENHI-PLANNED-20H05798, KAKENHI-PROJECT-21H02646, KAKENHI-PROJECT-21K06682, KAKENHI-PROJECT-21K07914, KAKENHI-PROJECT-19K17745
[Journal Article] Effects of Palonosetron on Nausea and Vomiting Induced by Multiple-Day Chemotherapy: A Retrospective Study2021
- Author(s)
  Hamano H, Mitsuhashi C, Suzuki Y, Zamami Y, Tsujinaka K, Okada N, Niimura T, Hayama T, Imai T, Ishida S, Sakamoto K, Goda M, Takechi K, Yagi K, Chuma M, Horinouchi Y, Shinomiya K, Ikeda Y, Kirino Y, Nakamura T, Yanagawa H, Hamada Y, Ishizawa K.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 4 Pages: 478-484
- DOI
  10.1248/bpb.b20-00609
- NAID
  130008014271
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06785, KAKENHI-PLANNED-20H05799, KAKENHI-PROJECT-21H02646, KAKENHI-PROJECT-20K07132, KAKENHI-PROJECT-21K06682
[Journal Article] Investigation of drugs affecting hypertension in bevacizumab‐treated patients and examination of the impact on the therapeutic effect2020
- Author(s)
  Yagi Kenta、Mitstui Marin、Zamami Yoshito、Niimura Takahiro、Izawa‐Ishizawa Yuki、Goda Mitsuhiro、Chuma Masayuki、Fukunaga Kimiko、Shibata Takahiro、Ishida Shunsuke、Sakurada Takumi、Okada Naoto、Hamano Hirofumi、Horinouchi Yuya、Ikeda Yasumasa、Yanagawa Hiroaki、Ishizawa Keisuke
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 1 Pages: 164-172
- DOI
  10.1002/cam4.3587
- NAID
  120007147667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-19K07321, KAKENHI-PROJECT-19K16448, KAKENHI-PLANNED-20H05799, KAKENHI-PROJECT-19J11675, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PLANNED-20H05798
[Journal Article] Deletion of H-ferritin in macrophages alleviates obesity and diabetes induced by high-fat diet in mice2020
- Author(s)
  Ikeda Yasumasa、Watanabe Hiroaki、Shiuchi Tetsuya、Hamano Hirofumi、Horinouchi Yuya、Imanishi Masaki、Goda Mitsuhiro、Zamami Yoshito、Takechi Kenshi、Izawa-Ishizawa Yuki、Miyamoto Licht、Ishizawa Keisuke、Aihara Ken-ichi、Tsuchiya Koichiro、Tamaki Toshiaki
- Journal Title
  
  Diabetologia
  
  Volume: 63 Issue: 8 Pages: 1588-1602
- DOI
  10.1007/s00125-020-05153-0
- NAID
  120007039998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-19K07321, KAKENHI-PROJECT-18K19745, KAKENHI-PROJECT-18H03152, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983
[Journal Article] Rho-associated protein kinase and cyclophilin A are involved in inorganic phosphate-induced calcification signaling in vascular smooth muscle cells2020
- Author(s)
  Tatsuya Tsuda, Masaki Imanishi, Mizuho Oogoshi, Yoshitaka Kihira, Yuya Horinouchi, Yoshito Zamami, Keisuke Ishizawa, Yasumasa Ikeda, Ichiro Hashimoto, Toshiaki Tamaki, Yuki Izawa-Ishizawa
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 142 Issue: 3 Pages: 109-115
- DOI
  10.1016/j.jphs.2019.12.005
- NAID
  120006980541
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-19K07321, KAKENHI-PROJECT-18K14983
[Journal Article] Proton pump inhibitors block iron absorption through direct regulation of hepcidin via the aryl hydrocarbon receptor-mediated pathway2020
- Author(s)
  Hamano Hirofumi、Niimura Takahiro、Horinouchi Yuya、Zamami Yoshito、Takechi Kenshi、Goda Mitsuhiro、Imanishi Masaki、Chuma Masayuki、Izawa-Ishizawa Yuki、Miyamoto Licht、Fukushima Keijo、Fujino Hiromichi、Tsuchiya Koichiro、Ishizawa Keisuke、Tamaki Toshiaki、Ikeda Yasumasa
- Journal Title
  
  Toxicology Letters
  
  Volume: 318 Pages: 86-91
- DOI
  10.1016/j.toxlet.2019.10.016
- NAID
  120006894295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-19K07321, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-19H00341, KAKENHI-PROJECT-17K18262, KAKENHI-PROJECT-19K16374, KAKENHI-PROJECT-19K16448, KAKENHI-PROJECT-19J11675
[Journal Article] Fibroblast-specific ERK5 deficiency changes tumor vasculature and exacerbates tumor progression in a mouse model.2020
- Author(s)
  Masaki Imanishi, Yusuke Yamakawa, Keijo Fukushima, Raiki Ikuto, Akiko Maegawa, Yuki Izawa-Ishizawa, Yuya Horinouchi, Masateru Kondo, Masatoshi Kishuku, Mitsuhiro Goda, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Yasumasa Ikeda, Koichiro Tsuchiya, Hiromichi Fujino, Koichi Tsuneyama, Keisuke Ishizawa
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology
  
  Volume: - Issue: 7 Pages: 1239-1250
- DOI
  10.1007/s00210-020-01859-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07321, KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-19K16374, KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983
[Journal Article] Iron accumulation causes impaired myogenesis correlated with MAPK signaling pathway inhibition by oxidative stress2019
- Author(s)
  Ikeda Yasumasa、Satoh Akiho、Horinouchi Yuya、Hamano Hirofumi、Watanabe Hiroaki、Imao Mizuki、Imanishi Masaki、Zamami Yoshito、Takechi Kenshi、Izawa‐Ishizawa Yuki、Miyamoto Licht、Hirayama Tasuku、Nagasawa Hideko、Ishizawa Keisuke、Aihara Ken‐Ichi、Tsuchiya Koichiro、Tamaki Toshiaki
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 8 Pages: 9551-9564
- DOI
  10.1096/fj.201802724rr
- NAID
  120006847086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-19K07321, KAKENHI-PROJECT-18K14983
[Journal Article] Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses2019
- Author(s)
  Izawa-Ishizawa Yuki、Imanishi Masaki、Zamami Yoshito、Toya Hiroki、Nagao Tomoko、Morishita Marin、Tsuneyama Koichi、Horinouchi Yuya、Kihira Yoshitaka、Takechi Kenshi、Ikeda Yasumasa、Tsuchiya Koichiro、Yoshizumi Masanori、Tamaki Toshiaki、Ishizawa Keisuke
- Journal Title
  
  Journal of Hypertension
  
  Volume: 37 Issue: 1 Pages: 73-83
- DOI
  10.1097/hjh.0000000000001898
- NAID
  120006627861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08272, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-18K14920
[Journal Article] Body iron accumulation in obesity, diabetes and its complications, and the possibility of therapeutic application by iron regulation2019
- Author(s)
  Horinouchi Yuya、Ikeda Yasumasa、Tamaki Toshiaki
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 154 Issue: 6 Pages: 316-321
- DOI
  10.1254/fpj.154.316
- NAID
  130007754372
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983
[Journal Article] Irinotecan-induced neutropenia is reduced by oral alkalization drugs: analysis using retrospective chart reviews and the spontaneous reporting database2018
- Author(s)
  Hamano Hirofumi、Mitsui Marin、Zamami Yoshito、Takechi Kenshi、Nimura Takahiro、Okada Naoto、Fukushima Keijo、Imanishi Masaki、Chuma Masayuki、Horinouchi Yuya、Izawa-Ishizawa Yuki、Kirino Yasushi、Nakamura Toshimi、Teraoka Kazuhiko、Ikeda Yasumasa、Fujino Hiromichi、Yanagawa Hiroaki、Tamaki Toshiaki、Ishizawa Keisuke
- Journal Title
  
  Supportive Care in Cancer
  
  Volume: 27 Issue: 3 Pages: 849-856
- DOI
  10.1007/s00520-018-4367-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08308, KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08549
[Journal Article] Renoprotective effects of a factor Xa inhibitor: fusion of basic research and a database analysis2018
- Author(s)
  Horinouchi Yuya、Ikeda Yasumasa、Fukushima Keijo、Imanishi Masaki、Hamano Hirofumi、Izawa-Ishizawa Yuki、Zamami Yoshito、Takechi Kenshi、Miyamoto Licht、Fujino Hiromichi、Ishizawa Keisuke、Tsuchiya Koichiro、Tamaki Toshiaki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10858-10858
- DOI
  10.1038/s41598-018-29008-2
- NAID
  120006535061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08308, KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-18K14920
[Journal Article] Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate2018
- Author(s)
  Tsuda K, Miyamoto L, Hamano S, Morimoto Y, Kangawa Y, Fukue C, Kagawa Y, Horinouchi Y, Xu W, Ikeda Y, Tamaki T, Tsuchiya K
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 4 Pages: 555-563
- DOI
  10.1248/bpb.b17-00855
- NAID
  130006602520
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02898, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08273
[Journal Article] Xanthine oxidase inhibition by febuxostat in macrophages suppresses angiotensin II-induced aortic fibrosis2018
- Author(s)
  Kondo Masateru、Imanishi Masaki、Fukushima Keijo、Ikuto Raiki、Murai Yoichi、Horinouchi Yuya、Izawa-Ishizawa Yuki、Goda Mitsuhiro、Zamami Yoshito、Takechi Kenshi、Chuma Masayuki、Ikeda Yasumasa、Fujino Hiromichi、Tsuchiya Koichiro、Ishizawa Keisuke
- Journal Title
  
  American Journal of Hypertension
  
  Volume: 32 Issue: 3 Pages: 249-256
- DOI
  10.1093/ajh/hpy157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08308, KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-17K18262, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-18K14920
[Journal Article] Nitrosonifedipine, a photodegradation product of nifedipine, suppresses pharmacologically induced aortic aneurysm formation2018
- Author(s)
  Imanishi Masaki、Izawa-Ishizawa Yuki、Sakurada Takumi、Kohara Yusuke、Horinouchi Yuya、Sairyo Eriko、Zamami Yoshito、Takechi Kenshi、Chuma Masayuki、Fukushima Keijo、Ikeda Yasumasa、Fujino Hiromichi、Yoshizumi Masanori、Tsuchiya Koichiro、Tamaki Toshiaki、Ishizawa Keisuke
- Journal Title
  
  Pharmacology
  
  Volume: 102 Issue: 5-6 Pages: 287-299
- DOI
  10.1159/000492577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08308, KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K06785, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-18K14920
[Journal Article] Hydrocortisone administration was associated with improved survival in Japanese patients with cardiac arrest.2017
- Author(s)
  48)Niimura T, Zamami Y, Koyama T, Izawa-Ishizawa Y, Miyake M, Koga T, Harada K, Ohshima A, Imai T, Kondo Y, Imanishi M, Takechi K, Fukushima K, Horinouchi Y, Ikeda Y, Fujino H, Tsuchiya K, Tamaki T, Hinotsu S, Kano MR, Ishizawa K.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 17919-17919
- DOI
  10.1038/s41598-017-17686-3
- NAID
  120006535027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-17K08308, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-15K21178, KAKENHI-PROJECT-16K16603
[Journal Article] Dietary iron restriction alleviates renal tubulointerstitial injury induced by protein overload in mice2017
- Author(s)
  Yasumasa Ikeda, Yuya Horinouchi, Hirofumi Hamano, Tasuku Hirayama, Seiji Kishi, Yuki Izawa-Ishizawa, Masaki Imanishi, Yoshito Zamami, Kenshi Takechi, Licht Miyamoto, Keisuke Ishizawa, Ken-ichi Aihara, Hideko Nagasawa, Koichiro Tsuchiya, and Toshiaki Tamaki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 10621-10621
- DOI
  10.1038/s41598-017-11089-0
- NAID
  120006534998
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-16H05102, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-16K16603, KAKENHI-PROJECT-16K18884
[Journal Article] Topical application of nitrosonifedipine, a novel radical scavenger, ameliorates ischemic skin flap necrosis in a mouse model.2017
- Author(s)
  Yutaka Fukunaga, Yuki Izawa-Ishizawa, Yuya Horinouchi, Eriko Sairyo, Yasumasa Ikeda, Keisuke Ishizawa, Koichiro Tsuchiya, Yoshiro Abe, Ichiro Hashimoto, Toshiaki Tamaki.
- Journal Title
  
  Wound Repair and Regeneration
  
  Volume: 印刷中 Issue: 2 Pages: 217-223
- DOI
  10.1111/wrr.12510
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-16K16603, KAKENHI-PROJECT-16K20360, KAKENHI-PROJECT-15H02898, KAKENHI-PROJECT-15K01716
[Journal Article] The uremic toxin indoxyl sulfate interferes with iron metabolism by regulating hepcidin in chronic kidney disease2017
- Author(s)
  Hirofumi Hamano, Yasumasa Ikeda, Hiroaki Watanabe, Yuya Horinouchi, Yuki Izawa-Ishizawa, Masaki Imanishi, Yoshito Zamami, Kenshi Takechi, Licht Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: - Issue: 4 Pages: 586-597
- DOI
  10.1093/ndt/gfx252
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-16K16603, KAKENHI-PROJECT-16K18884, KAKENHI-PROJECT-17H00503, KAKENHI-PROJECT-18K08480
[Journal Article] Iron suppresses erythropoietin expression via oxidative stress-dependent hypoxia-inducible factor-2 alpha inactivation.2017
- Author(s)
  Oshima K, Ikeda Y, Horinouchi Y, Watanabe H, Hamano H, Kihira Y, Kishi S, Izawa-Ishizawa Y, Miyamoto L, Hirayama T, Nagasawa H, Ishizawa K, Tsuchiya K, Tamaki T
- Journal Title
  
  Laboratory Investigation.
  
  Volume: 印刷中 Issue: 5 Pages: 555-566
- DOI
  10.1038/labinvest.2017.11
- NAID
  120006763916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16603, KAKENHI-PROJECT-16K08272, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-15K01716
[Journal Article] Iron-induced skeletal muscle atrophy involves an Akt-forkhead box O3-E3 ubiquitin ligase-dependent pathway.2016
- Author(s)
  Yasumasa Ikeda, Mizuki Imao, Akiho Satoh, Hiroaki Watanabe, Hirofumi Hamano, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Licht Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Journal Title
  
  Journal of Trace Elements in Medicine and Biology
  
  Volume: 35 Pages: 66-76
- DOI
  10.1016/j.jtemb.2016.01.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-15H02898, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-16K08272, KAKENHI-PROJECT-16K08549
[Journal Article] Bilirubin exerts pro-angiogenic effects through an Akt-eNOS-dependent pathway2015
- Author(s)
  Yasumasa Ikeda, Hamano Hirofumi, Satoh Akiho, Horinouchi Yuya, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Ken-ichi Aihara, Koichiro Tsuchiya and Toshiaki Tamaki
- Journal Title
  
  Hypertension Research
  
  Volume: 38(11) Issue: 11 Pages: 733-740
- DOI
  10.1038/hr.2015.74
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-25461389, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] Angiotensin II alters the expression of duodenal iron transporters, hepatic hepcidin, and body iron distribution in mice2015
- Author(s)
  Soichiro Tajima, Yasumasa Ikeda, Hideaki Enomoto, Imao Mizuki, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Rihito Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki
- Journal Title
  
  European Journal of Nutrition
  
  Volume: 印刷中 Issue: 5 Pages: 709-719
- DOI
  10.1007/s00394-014-0749-1
- NAID
  120006732013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25750044, KAKENHI-PROJECT-26870409, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-15H02898
[Presentation] フィブラート系薬剤の腎保護効果に関する検討2022
- Author(s)
  村嶋優香，堀ノ内裕也，山田佑人，吉岡駿，福島圭穣，久禮匠，佐々木尚史，藤野裕道，四宮一昭，池田康将
- Organizer
  第61回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-21K06682
[Presentation] Nicorandil improve prognosis of cardiac arrest patient: A large-scale medical information analysis2019
- Author(s)
  Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Keisuke Ishizawa
- Organizer
  FIP2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] 肥満・糖尿病における鉄制御の意義2019
- Author(s)
  堀ノ内裕也、池田康将、玉置俊晃
- Organizer
  第48回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] Development of therapeutic agents using drug discovery tools and large-scale medical information2019
- Author(s)
  Yoshito Zamami, Yuki Izawa-Ishizawa, Takahiro Niimura, Mitsuhiro Goda, Naoto Okada, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Keisuke Ishizawa
- Organizer
  FIP2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] 大規模医療情報データベースを活用したシスプラチン誘発腎障害に対する新規予防薬の探索とその有効性の検証2019
- Author(s)
  合田光寛, 神田将哉, 前川晃子, 新村貴博, 石澤有紀, 座間味義人, 中馬真幸, 武智研志, 濱野裕章, 岡田直人, 福島圭穰, 藤野裕道, 土屋浩一郎, 堀ノ内裕也, 池田康将, 楊河宏章, 石澤啓介
- Organizer
  第40回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] 抗がん剤誘発末梢神経障害の予防薬開発を目的とした医療ビッグデータ解析および基礎研究2019
- Author(s)
  新村貴博, 座間味義人, 内藤優太朗, 川尻雄大, 合田光寛, 武智研志, 中馬真幸, 堀ノ内裕也, 石澤有紀, 池田康将, 石澤啓介
- Organizer
  第40回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] マクロファージフェリチン欠損は肥満・糖尿病における脂肪炎症を抑制する2019
- Author(s)
  堀ノ内裕也、池田康将、渡邉大晃、濱野裕章、石澤有紀、今西正樹、座間味義人、武智研志、宮本理人、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第48回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] 慢性腎不全関連サルコペニアにおける鉄代謝異常2019
- Author(s)
  堀ノ内裕也、池田康将、濱野裕章、今西正樹、福島圭穣、石澤有紀、合田光寛、座間味義人、武智研志、宮本理人、藤野裕道、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第6回日本サルコペニア・フレイル学会大会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] 基礎研究と医療ビッグデータ解析を融合させたドラッグ・リポジショニングへの試み2019
- Author(s)
  堀ノ内裕也、池田康将、福島圭穣、今西正樹、濱野裕章、石澤有紀、座間味義人、武智研志、藤野裕道、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第40回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] 医療ビッグデータ解析と基礎研究を融合した抗がん剤誘発末梢神経障害の予防薬開発2019
- Author(s)
  新村貴博, 座間味義人, 内藤優太朗, 川尻雄大, 合田光寛, 武智研志, 中馬真幸, 堀ノ内裕也, 石澤有紀, 池田康将, 石澤啓介
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] ケルセチンによる薬剤誘発性急性大動脈疾患発症抑制効果の検討2019
- Author(s)
  鈴木琴子, 石澤有紀, 合田光寛, 近藤正輝, 今西正樹, 座間味義人, 堀ノ内裕也, 武智研志, 中馬真幸, 池田康将, 石澤啓介
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] 疾患における鉄の意義と治療応用2019
- Author(s)
  堀ノ内裕也、池田康将、玉置俊晃
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] 大規模医療情報を活用した抗がん剤誘発心筋症予防薬の探索2019
- Author(s)
  新村貴博, 座間味義人, 齊藤広海, 神田将哉, 合田光寛, 武智研志, 中馬真幸, 石澤有紀, 堀ノ内裕也, 池田康将, 石澤啓介
- Organizer
  第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学術集会
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] ドラッグリポジショニング手法を用いたシスプラチン誘発腎障害に対する新規予防薬探索2019
- Author(s)
  合田光寛, 神田将哉, 前川晃子, 吉田愛美, 新村貴博, 石澤有紀, 座間味義人, 中馬真幸, 武智研志, 福島圭穣, 藤野裕道, 土屋浩一郎, 堀ノ内　裕也, 池田康将, 石澤啓介
- Organizer
  第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学術集会
- Data Source
  KAKENHI-PROJECT-19K07321
[Presentation] 慢性腎不全関連骨格筋萎縮における鉄代謝異常2019
- Author(s)
  堀ノ内裕也、池田康将、濱野裕章、今西正樹、福島圭穣、合田光寛、武智研志、宮本理人、石澤有紀、座間味義人、藤野裕道、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] リアルワールドデータを活用した新規腎保護薬の探索2018
- Author(s)
  堀ノ内裕也、池田康将、福島圭穣、石澤有紀、藤野裕道、玉置俊晃
- Organizer
  第48回日本腎臓学会西部学術大会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] Utilizing Real-World Big Data in the Search for New Renoprotective Drugs2018
- Author(s)
  Yuya Horinouchi、Yasumasa Ikeda、Keijo Fukushima、Masaki Imanishi、Hirofumi Hamano、Yuki Izawa-Ishizawa、Yoshito Zamami、Hiromichi Fujino、Keisuke Ishizawa、Koichiro Tsuchiya、Toshiaki Tamaki
- Organizer
  Joint Hypertension 2018 Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] マクロファージ鉄の肥満・糖尿病における役割2018
- Author(s)
  堀ノ内裕也、池田康将、渡邉大晃、濱野裕章、石澤有紀、今西正樹、座間味義人、武智研志、宮本理人、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第42回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] 第Xa因子阻害剤の腎保護効果2018
- Author(s)
  堀ノ内裕也、池田康将、福島圭穣、今西正樹、石澤有紀、座間味義人、藤野裕道、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第47回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] Renoprotective effects of edoxaban, a factor Xa inhibitor2018
- Author(s)
  Yuya Horinouchi、Yasumasa Ikeda、Keijo Fukushima、Masaki Imanishi、Yuki Izawa-Ishizawa、Yoshito Zamami、Hiromichi Fujino、Keisuke Ishizawa、Koichiro Tsuchiya、Toshiaki Tamaki
- Organizer
  WCP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] リアルワールドビッグデータを活用した新規腎保護薬の探索2018
- Author(s)
  堀ノ内裕也、池田康将、福島圭穣、濱野裕章、今西正樹、石澤有紀、座間味義人、武智研志、藤野裕道、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第28回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] 慢性腎不全関連サルコペニアにおける鉄の関与2018
- Author(s)
  堀ノ内裕也、池田康将、濱野裕章、今西正樹、福島圭穣、武智研志、宮本理人、石澤有紀、座間味義人、藤野裕道、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] 大規模医療情報データベースを活用した新規腎保護薬の探索2018
- Author(s)
  堀ノ内裕也、池田康将、福島圭穣、今西正樹、濱野裕章、石澤有紀、座間味義人、藤野裕道、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  医療薬学フォーラム2018　第26回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K14983
[Presentation] DIRECT FACTOR XA INHIBITOR PREVENTS RENAL INTERSTITIAL FIBROSIS IN MICE WITH UNILATERAL URETERAL OBSTRUCTIO2017
- Author(s)
  Yasumasa Ikeda, Yuya Horinouchi, Yuki Izawa-Ishizawa, Toshiaki Tamaki
- Organizer
  54th ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] Direct factor Xa inhibitor prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction2017
- Author(s)
  Yasumasa Ikeda, Yuya Horinouchi, Yuki Izawa-Ishizawa, Toshiaki Tamaki
- Organizer
  54th ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 鉄摂取制限による尿細管間質障害の抑制効果の検討2017
- Author(s)
  池田康将, 堀ノ内裕也, 濱野裕章, 平山祐, 岸誠司, 石澤有紀, 今西正樹, 座間味義人, 武智研志, 宮本理人, 石澤啓介, 粟飯原賢一, 永澤秀子, 土屋浩一郎, 玉置俊晃
- Organizer
  第41回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] Indoxyl Sulfate Involves Abnormality of Iron Metabolism Through Hepcidin Regulation2017
- Author(s)
  Hirofumi Hamano, Yasumasa Ikeda, Hiroaki Watanabe, Yuya Horinouchi, Yuki Izawa-Ishizawa, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  Experimental Biology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] Factor Xa inhibitor attenuates renal interstitial fibrosis in mice with unilateral ureteral obstruction2017
- Author(s)
  Yuya Horinouchi, Yasumasa Ikeda, Masaki Imanishi, Yoshito Zamami, Yuki Izawa-Ishizawa, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  The 13th Congress of the European Association for Clinical Pharmacology and Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] Iron restriction prevents renal tubulointerstitial injury induced by albumin overload in mice2017
- Author(s)
  Yasumasa Ikeda, Yuya Horinouchi, Yuki Izawa-Ishizawa, Toshiaki Tamaki
- Organizer
  54th ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 第Xa因子阻害剤は腎間質線維化を抑制する2017
- Author(s)
  堀ノ内裕也、池田康将、石澤有紀、今西正樹、座間味義人、武智研志、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] FXa阻害剤は腎間質線維化を抑制する2017
- Author(s)
  堀ノ内裕也、池田康将、石澤有紀、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] IRON RESTRICTION PREVENTS RENAL TUBULOINTERSTITIAL INJURY INDUCED BY ALBUMIN OVERLOAD IN MICE2017
- Author(s)
  Yasumasa Ikeda, Yuya Horinouchi, Yuki Izawa-Ishizawa, Toshiaki Tamaki
- Organizer
  54th ERA-EDTA Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] Direct activated factor X inhibitor attenuates renal fibrosis on unilateral ureteral obstruction-induced nephrotoxicity2017
- Author(s)
  Yuya Horinouchi, Yasumasa Ikeda, Masaki Imanishi, Yoshito Zamami, Yuki Izawa-Ishizawa, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  53rd Congress of the European Societies of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 経口FXa阻害剤の腎線維化抑制効果2017
- Author(s)
  堀ノ内裕也、池田康将、今西正樹、座間味義人、石澤有紀、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  医療薬学フォーラム 2017 第25回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 慢性腎臓病における尿毒素蓄積によるヘプシジン制御と鉄代謝破綻のメカニズムの解明2017
- Author(s)
  濱野裕章、池田康将、渡邉大晃、堀ノ内裕也、石澤有紀、今西正樹、座間味義人、武智研志、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第41回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 肥満・糖尿病におけるマクロファージ鉄制御機構の検討2017
- Author(s)
  渡邉大晃、池田康将、濱野裕章、堀ノ内裕也、石澤有紀、今西正樹、座間味義人、武智研志、宮本理人、土屋浩一郎、玉置俊晃、石澤啓介
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 肥満・糖尿病におけるマクロファージ鉄の役割の検討2017
- Author(s)
  渡邉大晃、池田康将、濱野裕章、堀ノ内裕也、石澤有紀、今西正樹、座間味義人、武智研志、宮本理人、土屋浩一郎、玉置俊晃、石澤啓介
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 鉄摂取制限による尿細管間質障害の抑制効果の検討2017
- Author(s)
  池田康将、堀ノ内裕也、濱野裕章、平山祐、岸誠司、石澤有紀、今西正樹、座間味義人、武智研志、宮本理人、石澤啓介、粟飯原賢一、永澤秀子、土屋浩一郎、玉置俊晃
- Organizer
  第41回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] The effect of iron on skeletal muscle atrophy in chronic kidney disease2017
- Author(s)
  Yuya Horinouchi, Yasumasa Ikeda, Hirofumi Hamano, Masaki Imanishi, Yuki Izawa-Ishizawa, Yoshito Zamami, Kenshi Takechi, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  The Society for Redox Biology and Medicine's 24th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] Indoxyl sulfate involves abnormality of iron metabolism through hepcidin regulation2017
- Author(s)
  Hirofumi Hamano, Yasumasa Ikeda, Hiroaki Watanabe, Yuya Horinouchi, Yuki Izawa-Ishizawa, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  Experimental Biology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 新しい創薬標的としての鉄イオン2017
- Author(s)
  土屋浩一郎、池田康将、堀ノ内裕也、石澤有紀、宮本理人、玉置俊晃
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] インドキシル硫酸蓄積はヘプシジン制御を介して鉄代謝恒常性破綻に関与する2017
- Author(s)
  濱野裕章、池田康将、渡邉大晃、堀ノ内裕也、石澤有紀、今西正樹、座間味義人、武智研志、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] Factor Xa inhibitor attenuates renal fibrosis in mice with unilateral ureteral obstruction2017
- Author(s)
  Horinouchi Yuya, Ikeda Yasumasa, Izawa-Ishizawa Yuki, Ishizawa Keisuke, Tsuchiya Koichiro, Tamaki Toshiaki
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市)
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 慢性腎不全における尿毒素蓄積が生体内鉄代謝に与える影響の検討2017
- Author(s)
  濱野裕章, 池田康将, 渡邉大晃, 堀ノ内裕也, 佐藤明穂, 大島啓亮, 石澤有紀, 石澤啓介, 土屋浩一郎, 玉置俊晃
- Organizer
  第46回日本心脈管作動物質学会年会
- Place of Presentation
  琉球大学(沖縄県西原町)
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] Indoxyl Sulfate Disturbs Normal Iron Metabolism via Hepcidin Upregulation in Chronic Kidney Disease,2017
- Author(s)
  Hirofumi Hamano, Yasumasa Ikeda, Hiroaki Watanabe, Yuya Horinouchi, Yuki Izawa-Ishizawa, Masaki Imanishi, Yoshito Zamami, Kenshi Takechi, Licht Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  ASN Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] 鉄摂取制限はタンパク過剰負荷による尿細管間質障害を軽減する2017
- Author(s)
  池田康将, 堀ノ内裕也, 石澤有紀, 玉置俊晃
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] インドキシル硫酸はヘプシジンを介した鉄代謝異常に関与する2017
- Author(s)
  濱野裕章、池田康将、渡邉大晃、堀ノ内裕也、石澤有紀、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] FXa阻害剤の片側尿管結紮モデルマウスにおける腎間質線維化抑制作用2017
- Author(s)
  堀ノ内裕也, 池田康将, 石澤有紀, 石澤啓介, 土屋浩一郎, 玉置俊晃
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 慢性腎不全における尿毒素蓄積が生体内鉄代謝に与える影響の検討2017
- Author(s)
  濱野　裕章、池田　康将、渡邉　大晃、堀ノ内　裕也、佐藤　明穂、大島　啓亮、石澤　有紀、石澤　啓介、土屋　浩一郎、玉置　俊晃
- Organizer
  第46回日本心脈管作動物質学会
- Place of Presentation
  琉球大学医学部（沖縄県・那覇市）
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] 鉄摂取制限はタンパク過剰負荷による尿細管間質障害を抑制する2017
- Author(s)
  池田康将、堀ノ内裕也、石澤有紀、玉置俊晃
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 鉄欠乏が骨格筋に与える作用の検討2016
- Author(s)
  佐藤明穂、池田康将、濱野裕章、堀ノ内裕也、今尾瑞季、渡邉大晃、石澤有紀、宮本理人、石澤啓介、玉置俊晃、土屋浩一郎
- Organizer
  第55回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  岡山コンベンションセンター（岡山県・岡山市）
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] 骨格筋分化における鉄の役割2016
- Author(s)
  池田康将, 佐藤明穂, 堀ノ内裕也, 石澤有紀, 宮本理人, 石澤啓介, 土屋浩一郎, 玉置俊晃
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県・広島市）
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] 骨格筋分化における鉄の役割2016
- Author(s)
  池田康将、佐藤明穂、堀ノ内裕也、石澤有紀、宮本理人、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館(広島県広島市)
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] 鉄欠乏が骨格筋に与える作用の検討2016
- Author(s)
  佐藤明穂、池田康将、濱野裕章、堀ノ内裕也、今尾瑞季、渡邉大晃、石澤有紀、宮本理人、石澤啓介，玉置俊晃、土屋浩一郎
- Organizer
  第55回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  就実大学(岡山県岡山市)
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] The new insight of iron on tissue damage in metabolic disorders2016
- Author(s)
  Yasumasa Ikeda, Yuya Horinouchi, Yuki Izawa-Ishizawa, Toshiaki Tamaki
- Organizer
  The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide/The 16th Annual Scientific Meeting of the Nitric Oxide Society of Japan
- Place of Presentation
  Sendai International Center(宮城県仙台市)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] Iron Supplementation Suppressed Erythropoietin Expression through HIF-Dependent Pathway2016
- Author(s)
  Yasumasa Ikeda, Keisuke Oshima, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] The new insight of iron on tissue damage in metabolic disorders.2016
- Author(s)
  Yasumasa Ikeda, Yuya Horinouchi, Yuki Izawa-Ishizawa, Toshiaki Tamaki
- Organizer
  The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide/16th Annual Scientific Meeting of the Nitric Oxide Society of Japan.
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] The Involvement of Iron Supplementation on Erythropoietin Expression2016
- Author(s)
  Yasumasa Ikeda, Oshima Keisuke, Horinouchi Yuya, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki
- Organizer
  Experimental Biology 2016
- Place of Presentation
  SanDiego（USA)
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] The Involvement of Iron Supplementation on Erythropoietin Expression2016
- Author(s)
  Yasumasa Ikeda, Oshima Keisuke, Horinouchi Yuya, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  Experimental Biology 2016
- Place of Presentation
  Chicago(USA)
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16603
[Presentation] Bilirubin Enhances Ischimia-induced Angiogenesis Through Akt-eNOS-Dependent Signaling Pathway2015
- Author(s)
  Yasumasa Ikeda, Hamano Hirofumi, Horinouchi Yuya, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716
[Presentation] 鉄欠乏は骨格筋量減少の原因となる2015
- Author(s)
  池田康将, 佐藤明穂, 堀ノ内裕也, 石澤有紀, 木平孝高, 石澤啓介, 土屋浩一郎, 玉置俊晃
- Organizer
  第39回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-15K01716

1. IKEDA Yasumasa (60432754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
2. IZAWA-ISHIZAWA Yuki (40610192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
3. 八木秀介 (00507650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 中馬真幸 (20819289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. 座間味義人 (70550250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
6. 武智研志 (90793240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
7. 合田光寛 (40585965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
8. HAMANO Hirofumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. IMAO Mizuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SATO Akiho

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. WATANABE Hiroaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. ABE Jun-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. ISHIZAWA Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. TAJIMA Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 今西正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
16. 藤野裕道

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Horinouchi Yuya 堀ノ内 裕也

HORINOUCHI Yuya 堀ノ内 裕也

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トランスレーショナルリサーチを志向した慢性腎臓病の新たな薬物療法の基盤確立Principal Investigator

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ビッグデータ解析と基礎研究を融合した慢性腎臓病の機序解明と新しい治療戦略開発Principal Investigator

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Elucidation of the role of ERK5 and the mechanism of epithelial-mesenchymal transition for cancer metastasis control

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Development of new treatment strategy for chronic kidney disease using medical big dataPrincipal Investigator

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Molecular mechanism elucidation of iron metabolism abnormality and sarcopenia onset in chronic renal failurePrincipal Investigator

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The role of iron on sarcopenia, and the therapeutic significance of iron regulation for anti-sarcopenia

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[Journal Article] Pemafibrate inhibited renal dysfunction and fibrosis in a mouse model of adenine-induced chronic kidney disease2023

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[Journal Article] Examination of the antiepileptic effects of valacyclovir using kindling mice― search for novel antiepileptic agents by drug repositioning using a large medical information database2021

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[Journal Article] Role of ferroptosis in cisplatin-induced acute nephrotoxicity in mice.2021

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[Journal Article] Diphenhydramine may be a preventive medicine against cisplatin-induced kidney toxicity2021

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[Journal Article] Effects of Palonosetron on Nausea and Vomiting Induced by Multiple-Day Chemotherapy: A Retrospective Study2021

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[Journal Article] Investigation of drugs affecting hypertension in bevacizumab‐treated patients and examination of the impact on the therapeutic effect2020

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[Journal Article] Deletion of H-ferritin in macrophages alleviates obesity and diabetes induced by high-fat diet in mice2020

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Horinouchi Yuya 堀ノ内裕也

HORINOUCHI Yuya 堀ノ内裕也