Sanada Fumihiro 眞田文博

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SANADA Fumihiro 眞田文博

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Researcher Number	30722227
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 寄附講座准教授
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院医学系研究科, 寄附講座准教授 2022: 大阪大学, 大学院医学系研究科, 寄附講座准教授 2017 – 2021: 大阪大学, 医学系研究科, 寄附講座准教授 2016: 大阪大学, 医学系研究科, 寄附講座助教 2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 特任助教 2014: 大阪大学, 医学(系)研究科(研究院), 助教 2014: 大阪大学, 大学院医学系研究科, 寄附講座特任助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Pathological medical chemistry / Cardiovascular medicine Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Thoracic surgery
Keywords	Principal Investigator 慢性心不全 / 治療抵抗性乳がん / ペリオスチン / 選択的スプライシングバリアント / splicing variant swich / 選択的スプライシング / 抗癌剤治療抵抗性乳癌 / トリプルネガティブ乳がん / ペリオスリン / 細胞外マトリックス蛋白 / 心不全 … More Except Principal Investigator … More ペリオスチン / 乳癌 / 腹部大動脈瘤 / ぺリオスチン / 川崎病 / 動脈瘤 / メカニカルストレス / 腹部動脈瘤 Less

「ペリオスチン」をターゲットに、乳癌の治療抵抗性の解除に挑む
- Principal Investigator
  
  金本佑子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka University
Development of new therapeutics and diagnostics for breast cancer targeting specific alternative splicing variantsPrincipal Investigator
- Principal Investigator
  
  Sanada Fumihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Osaka University
Abnormalities in alternative splicing in cancer; therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  SANADA FUMIHIRO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
The role of resident stem cell in the progression of heart failurePrincipal Investigator
- Principal Investigator
  
  SANADA FUMIHIRO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
New theraputic strategy to treat abdominal aortic anerysm via mechano-stress reguratory factor: periostin
- Principal Investigator
  
  JUNYA AZUMA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 遺伝子治療・診断の最先端技術と新しい医薬品・診断薬の開発2014
- Author(s)
  谷山義明、東純哉、眞田文博、楽木宏実、森下竜一
- Total Pages
  566
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-24592063
[Journal Article] 病的ペリオスチンバリアントをターゲットにした乳がん治療法の開発2022
- Author(s)
  眞田文博, 谷山義明, 藤川龍弥, 柴田佳那, 楽木宏実, 森下竜一
- Journal Title
  
  Precision Medicine
  
  Volume: 15 Pages: 80-83
- Data Source
  KAKENHI-PROJECT-20K07659
[Journal Article] Periostin Exon-21 Antibody Neutralization of Triple-Negative Breast Cancer Cell-Derived Periostin Regulates Tumor-Associated Macrophage Polarization and Angiogenesis.2021
- Author(s)
  Fujikawa T, Sanada F, Taniyama Y, Shibata K, Katsuragi N, Koibuchi N, Akazawa K, Kanemoto Y, Kuroyanagi H, Shimazu K, Rakugi H, Morishita R.
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 20 Pages: 5072-5086
- DOI
  10.3390/cancers13205072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07659, KAKENHI-PROJECT-18H02806
[Journal Article] Periostin Short Fragment with Exon 17 via Aberrant Alternative Splicing Is Required for Breast Cancer Growth and Metastasis2021
- Author(s)
  Yuka Ikeda-Iwabu, Yoshiaki Taniyama, Naruto Katsuragi, Fumihiro Sanada, Nobutaka Koibuchi, Kana Shibata, Kenzo Shimazu, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 4 Pages: 892-892
- DOI
  10.3390/cells10040892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07466, KAKENHI-PROJECT-20K07659, KAKENHI-PROJECT-18H02806
[Journal Article] 治療抵抗性トリプルネガティブ乳がん治療法の開発2020
- Author(s)
  眞田文博、谷山義明、藤川龍弥、柴田佳那、楽木宏実、森下竜一
- Journal Title
  
  Precision Medicine
  
  Volume: 13 Pages: 75-78
- Data Source
  KAKENHI-PROJECT-20K07659
[Journal Article] 化学療法抵抗性トリプルネガティブ乳がん新規治療法の開発2020
- Author(s)
  眞田文博、谷山義明、藤川龍弥、柴田佳那、森下竜一
- Journal Title
  
  Precision Medicine
  
  Volume: 45 Pages: 367-370
- Data Source
  KAKENHI-PROJECT-20K07659
[Journal Article] ペリオスチン選択的スプライシングバリアントをターゲットにした治療抵抗性乳癌新規治療法の開発2019
- Author(s)
  眞田文博、谷山義明、藤川龍弥、柴田佳那、森下竜一
- Journal Title
  
  Medical Science Digest 乳がんの最新治療と課題
  
  Volume: 45 Pages: 518-520
- Data Source
  KAKENHI-PROJECT-17K08660
[Journal Article] Endothelial Progenitor Cells in Clinical Settings2014
- Author(s)
  Sanada F, Taniyama Y, Azuma J, Ikeda-Iwabe Y, Iwabayashi M, Rakugi H, Morishita R;
- Journal Title
  
  J Stem Cells
  
  Volume: 9(2) Pages: 117-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592063
[Journal Article] Therapeutic angiogenesis by gene therapy for critical limb ischemia - Choice of biological agent -2014
- Author(s)
  Sanada F, Taniyama Y, Azuma J, Ikeda-Iwabe Y, Iwabayashi M, Kanbara Y, Rakugi H, Morishita R
- Journal Title
  
  Endoc.& Metab Agents in Med Chem
  
  Volume: ８ Issue: 1 Pages: 32-39
- DOI
  10.2174/1871522213999131231105139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592063
[Journal Article] Evaluation of pregabalin therapy in peripheral neuropathy2013
- Author(s)
  Shimizu K, Taniyama Y, Azuma J, Sanada F, Iwabayashi M, Yamane Y, Yamasaki H, Akasaki A, and Morishita R
- Journal Title
  
  Immunology, Endoc. & Metab Agents in Med Chem
  
  Volume: 13 Issue: 2 Pages: 132-138
- DOI
  10.2174/1871522211313020007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592063
[Journal Article] Novel mechanism of hepatocyte growth factor against prevention of inflammation and oxidative stress2013
- Author(s)
  Shimizu K, Taniyama Y, Sanada F, Iwabayashi M, Azuma J, Iekushi K, Katsuragi N, Otsu R, Shibata K, Ishikawa Y, Rakugi H, Morishita R
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33（3） Pages: 136-142
- NAID
  130004943842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592063
[Presentation] ペリオスチンはトリプルネガティブ乳がんの予後予測因子である2021
- Author(s)
  眞田文博、谷山義明、楽木宏実、森下竜一
- Organizer
  本内科学会第232回近畿地方会
- Data Source
  KAKENHI-PROJECT-20K07659
[Presentation] POSTNの選択的スプライシングと癌の微小環境2021
- Author(s)
  柴田佳那、谷山義明、眞田文博、葛城鳴門、鯉渕信孝、池田（岩部）裕香、村津淳、藤川龍弥、金本佑子、赤澤香、中川涼子、平本はるか、島津研三、楽木宏実、森下竜一
- Organizer
  第21回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-20K07659
[Presentation] 抗癌剤治療抵抗性トリプルネガティブ乳がんにおける新規治療法の創出2021
- Author(s)
  藤川龍弥、眞田文博、谷山義明、葛城鳴門、鯉渕信孝、柴田佳那、中川涼子、楽木宏実、森下竜一
- Organizer
  第21回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-20K07659
[Presentation] 抗癌剤治療抵抗性トリプルネガティブ乳がんに対する治療法の確立2020
- Author(s)
  藤川龍弥、眞田文博、谷山義明、柴田佳那、葛城鳴門、鯉渕信孝、中川涼子、楽木宏実、森下竜一
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07659
[Presentation] Periostinのスプライシング・バリアントを標的とした画期的乳癌治療学法の開発2019
- Author(s)
  柴田佳那、谷山義明、眞田文博、村津淳、藤川龍弥、中川涼子、鯉渕信孝、樂木宏実、森下竜一
- Organizer
  脳心血管抗加齢研究会
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] Blockade of Periostin Protected from development of inflammation in rhabdomyolysis-induced acute kidney injury2019
- Author(s)
  Jun Muratsu, Yoshiaki Taniyama, Fumihiro Sanada, Kana Shibata, Rei Ohtsu, Atsuyuki Morishima, Katsuhiko Sakaguchi, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  ERA-EDTA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] ペリオスチン選択的スプライシングバリアントによる乳がん治療抵抗性獲得メカニズムの解明2019
- Author(s)
  藤川龍弥、眞田文博、谷山義明、中川涼子、柴田佳那、鯉渕信孝、樂木宏実、森下竜一
- Organizer
  脳心血管抗加齢研究会
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] Specific inhibition of periostin alternative splicing variant ameriorata cardiacfibrosis after myocardial infarction2019
- Author(s)
  眞田　文博
- Organizer
  Cardio Renal Diabetes Conference
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] Periostinのスプライシング・バリアントを標的とした画期的乳癌治療法の開発2019
- Author(s)
  柴田佳那、谷山義明、眞田文博、村津淳、大津礼、藤川龍弥、中川涼子、ブルーレー・メイ・加和子、樂木宏実、森下竜一
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] Periostin splicing variant regulates cardiac fibrosis after myocardial infarction2018
- Author(s)
  Fumihiro Sanada, Yoshiaki Taniyama, Jun Muratsu, Tatsuya Fujikawa, Kana Shibata, Kanako May Brule, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  International Society of Hypertension 2018 Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] ペリオスチンスプライシング制御による治療抵抗性乳がん治療法の樹立2018
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、柴田佳那、ブルーレー・メイ・加和子、樂木宏実、森下竜一
- Organizer
  第18回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] ペリオスチン選択的スプライシングバリアント制御による治療抵抗性乳がん治療法の確立2018
- Author(s)
  藤川龍弥、眞田文博、谷山義明、村津淳、大津礼、柴田佳那、ブルーレー・メイ・加和子、樂木宏実、森下竜一
- Organizer
  脳心血管抗加齢研究会2018
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] Periostin splicing variant specific inhibition ameliorates heart failure after myocardial infarction.2018
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、樂木宏実、森下竜一
- Organizer
  第6回IRG (Inflammation and ReGeneration) Meeting
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] Selective blockade of periostin exon 17 inhibits cardiac and renal fibrosis2018
- Author(s)
  眞田文博
- Organizer
  Cardio Renal Diabetes Conference 2018
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] ペリオスチンスプライシング制御による難治性乳癌治療法の開発2017
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、柴田佳那、ブルーレー・メイ・加和子、樂木宏実、森下竜一
- Organizer
  Molecular Cardiovascular Metabolic Conference 2017
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] ペリオスチンスプラシングバリアントは抗がん剤抵抗性乳がんの治療ターゲットである2017
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、樂木宏実、森下竜一
- Organizer
  脳心血管抗加齢研究会2017
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] Periostin exon17の選択的阻害による腎線維化への影響2017
- Author(s)
  村津淳、眞田文博、谷山義明、大津礼、樂木宏実、森下竜一
- Organizer
  第21回日本心血管内分泌代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08660
[Presentation] 生活習慣病における最近の話題～スプライシングバリアントの役割を含めて～2016
- Author(s)
  眞田　文博
- Organizer
  Molecular Jungle
- Place of Presentation
  大阪リッツカールトンホテル
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] Selective blockade of periostin exon-17 improves cardiac performance in rat myocardial ischemia model2016
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、楽木宏実、森下竜一
- Organizer
  The 26th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Seoul、Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] Selective blockade of periostin exon-17 improves heart failure after myocardial infarction2016
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、楽木宏実、森下竜一
- Organizer
  American Herat Association Scientific Session 2016
- Place of Presentation
  Orland、USA
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] Selective blockade of periostin exon-17 ameliorates heart failure after myocardial infarction2016
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、楽木宏実、森下竜一
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  Boston、USA
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] マスト細胞の分化機能獲得におけるPeriostinの影響2016
- Author(s)
  村津淳、眞田文博、谷山義明、大津礼、柴田佳那、ブルーレー・メイ・加和子、樂木宏実、森下竜一
- Organizer
  脳心血管抗加齢研究会
- Place of Presentation
  秋葉原UDX
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] マスト細胞の分化機能獲得に対する細胞外マトリックスPeriostinの影響2016
- Author(s)
  村津淳、眞田文博、谷山義明、大津礼、柴田佳那、ブルーレー・メイ・加和子、樂木宏実、森下竜一
- Organizer
  第20回日本心血管内分泌代謝学会
- Place of Presentation
  東京コンベンションホール
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] ペリオスチン・スプライスバリアント制御による炎症性疾患治療法の確立2016
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、楽木宏実、森下竜一
- Organizer
  Molecular Cardiovascular Conference II
- Place of Presentation
  東京ドームホテル
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] ペリオスチン・スプライスバリアント制御による抗炎症効果の検討2016
- Author(s)
  眞田文博、谷山義明、村津淳、大津礼、柴田佳那、ブルーレー・メイ・加和子、楽木宏実、森下竜一
- Organizer
  脳心血管抗加齢研究会
- Place of Presentation
  秋葉原UDX
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] Selective Blockade of Periostin Exon-17 Ameriorates Cardiac Performance in Acute Myocardial Infarction2015
- Author(s)
  眞田　文博
- Organizer
  日本遺伝子治療学会学術集会、アジア・オセアニア遺伝子治療コンソーシアム
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] 液性因子による組織恒常性の破綻と維持炎症性疾患におけるペリオスチンバリアントの役割2015
- Author(s)
  眞田　文博
- Organizer
  脳心血管抗加齢研究会
- Place of Presentation
  大阪梅田スカイビル
- Year and Date
  2015-11-18
- Invited
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] Stem Cell Factor Activates Hypoxic Carduac Stem Cells reversing Myocardial Aging.
- Author(s)
  眞田　文博
- Organizer
  第22回日本血管生物医学会学術集会
- Place of Presentation
  京都市勧業館みやこめっせ
- Year and Date
  2014-04-16 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-26860560
[Presentation] Hypoxic and normoxic cardiac stem cell dictats myocardial aging
- Author(s)
  眞田　文博
- Organizer
  第14回日本抗加齢医学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-06-06 – 2014-06-08
- Data Source
  KAKENHI-PROJECT-26860560

1. TANIYAMA Yoshiaki (60372611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. JUNYA AZUMA (20614671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 黒柳秀人 (30323702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 伊藤薫 (50375664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 金本佑子 (30924930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORISHITA RYUICHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. 岩部裕香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sanada Fumihiro 眞田 文博

SANADA Fumihiro 眞田 文博

Research Projects

Research Products

Co-Researchers

「ペリオスチン」をターゲットに、乳癌の治療抵抗性の解除に挑む

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new therapeutics and diagnostics for breast cancer targeting specific alternative splicing variantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Abnormalities in alternative splicing in cancer; therapeutic targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of resident stem cell in the progression of heart failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New theraputic strategy to treat abdominal aortic anerysm via mechano-stress reguratory factor: periostin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 遺伝子治療・診断の最先端技術と新しい医薬品・診断薬の開発2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] 病的ペリオスチンバリアントをターゲットにした乳がん治療法の開発2022

Author(s)

Journal Title

Data Source

[Journal Article] Periostin Exon-21 Antibody Neutralization of Triple-Negative Breast Cancer Cell-Derived Periostin Regulates Tumor-Associated Macrophage Polarization and Angiogenesis.2021

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[Journal Article] Evaluation of pregabalin therapy in peripheral neuropathy2013

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Sanada Fumihiro 眞田文博

SANADA Fumihiro 眞田文博