Fujii Yumiko 藤井裕美子

… Alternative Names

FUJII Yumiko 藤井裕美子

FUJII YUMIKO 藤井裕美子

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Researcher Number	30722334
Other IDs
Affiliation (Current)	2025: 旭川医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 旭川医科大学, 医学部, 助教 2017 – 2018: 東京大学, 大学院医学系研究科(医学部), 特任助教 2015: 東京大学, 医学(系)研究科(研究院), 特任助教 2014 – 2015: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 49030:Experimental pathology-related
Keywords	Principal Investigator ヘリコバクター・ピロリ / 脂質ホスファターゼ / 胃がん / CagA / 肝内胆管がん / 感染がん / 細菌 / へリコバクター・ピロリ / がん / 胃粘膜病変 / 細胞間接着 / 脱リン酸化 / 化生 … More Except Principal Investigator … More 胆管癌 / 原発性肝癌 / 分化転換」 / 脱分化 / 分化転換 / 混合型肝癌 / 胆管細胞癌 / 肝細胞癌 / 肝腫瘍 Less

胆管上皮細胞におけるSHIP2脂質ホスファターゼの核内機能とその発がんへの関与Principal Investigator
- Principal Investigator
  
  藤井裕美子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
Analysis of the phosphatase that is a novel binding target for the Helicobacter pylori virulence factor CagA in the host cellsPrincipal Investigator
- Principal Investigator
  
  FUJII Yumiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
Mechanisms determining the wide spectrum of hepatocytic tumors
- Principal Investigator
  
  Nishikawa Yuji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Asahikawa Medical College
Helicobacter pylori CagA-induced dephosphorylation of E-cadherin and its involvement in carcinogenesisPrincipal Investigator
- Principal Investigator
  
  FUJII Yumiko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Molecular mechanism of gastric carcinogenesis through restricted dedifferentiation by Helicobacter pylori CagAPrincipal Investigator
- Principal Investigator
  
  FUJII YUMIKO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2015 2014

All Journal Article Presentation

[Journal Article] High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation2023
- Author(s)
  Goto Masanori、Ooshio Takako、Yamamoto Masahiro、Tanaka Hiroki、Fujii Yumiko、Meng Lingtong、Kamikokura Yuki、Okada Yoko、Nishikawa Yuji
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1869 Issue: 4 Pages: 166644-166644
- DOI
  10.1016/j.bbadis.2023.166644
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03448, KAKENHI-PROJECT-20K07558, KAKENHI-PROJECT-23K06667, KAKENHI-PROJECT-20K07443
[Journal Article] Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice2021
- Author(s)
  Meng Lingtong、Goto Masanori、Tanaka Hiroki、Kamikokura Yuki、Fujii Yumiko、Okada Yoko、Furukawa Hiroyuki、Nishikawa Yuji
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 191 Issue: 9 Pages: 1580-1591
- DOI
  10.1016/j.ajpath.2021.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03448
[Journal Article] Hepatocyte MKK7 Contributes to Restoration of the Liver Parenchyma Following Injury2020
- Author(s)
  Ooshio Takako、Yamamoto Masahiro、Fujii Kiyonaga、Xin Bing、Watanabe Kenji、Goto Masanori、Okada Yoko、Suzuki Akira、Penninger Josef M.、Nishina Hiroshi、Nishikawa Yuji
- Journal Title
  
  Hepatology
  
  Volume: online Issue: 6 Pages: 31565-31565
- DOI
  10.1002/hep.31565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20661, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-19H03448, KAKENHI-PUBLICLY-20H04905, KAKENHI-PROJECT-21H04806, KAKENHI-PROJECT-20K07558
[Journal Article] Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells.2020
- Author(s)
  Fujii Y, Murata-Kamiya N, Hatakeyama M
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 1596-1606
- DOI
  10.1111/cas.14391
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08436, KAKENHI-PROJECT-19K07535, KAKENHI-PROJECT-16H06373
[Journal Article] Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations2019
- Author(s)
  Watanabe K, Yamamoto M, Xin B, Ooshio T, Goto M, Fujii K, Liu Y, Okada Y, Furukawa H, Nishikawa Y.
- Journal Title
  
  Hepatology Communications
  
  Volume: 3 Issue: 5 Pages: 697-715
- DOI
  10.1002/hep4.1327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17573, KAKENHI-PROJECT-19H03448
[Journal Article] Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein2015
- Author(s)
  Suzuki, N.
- Journal Title
  
  Sci. Rep/
  
  Volume: 5 Issue: 1 Pages: 10024-10024
- DOI
  10.1038/srep10024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22114001, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25250016, KAKENHI-PROJECT-26860495
[Presentation] 肝内胆管細胞における脂質ホスファターゼSHIP2の核内機能2023
- Author(s)
  藤井裕美子、後藤正憲、田中宏樹、上小倉佑機、岡田陽子、西川祐司
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K07976
[Presentation] 肝内胆管細胞における脂質ホスファターゼSHIP2の細胞核内機能2023
- Author(s)
  藤井裕美子、後藤正憲、田中宏樹、上小倉佑機、岡田陽子、西川祐司
- Organizer
  第56回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-22K07976
[Presentation] 血小板由来微小胞による肝腫瘍細胞の生存能促進2022
- Author(s)
  田中　宏樹、上小倉　佑機、後藤　正憲、藤井　裕美子、西川　祐司
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 慢性肝障害から発生する肝発癌におけるエピゲノム異常2022
- Author(s)
  Hiroki Tanaka, Masanori Goto, Yumiko Fujii, Yuki Kamikokura, Yuji Nishikawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 肝細胞がんにおけるがん遺伝子Mycとプロリン代謝酵素PRODHの関連2022
- Author(s)
  後藤　正憲、田中　宏樹、藤井　裕美子、上小倉　佑機、岡田　陽子、西川　祐司
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 活性型 AKT と YAP で誘導したマウス胆管癌表現型に対する Myc または Mycn の影響2022
- Author(s)
  後藤　正憲、田中　宏樹、藤井　裕美子、上小倉　佑機、岡田　陽子、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝腫瘍のNotch経路の活性化と胆管癌表現型に対するMycとMycnの影響2022
- Author(s)
  Masanori Goto, Hiroki Tanaka, Yumiko Fujii, Yuki Kamikokura, Yoko Okada, and Yuji Nishikawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 肝内胆管細胞におけるリン脂質ホスファターゼSHIP2の細胞核内機能と発がんへの関与2022
- Author(s)
  藤井裕美子、後藤正憲、田中宏樹、上小倉佑機、岡田陽子、西川祐司
- Organizer
  第124回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-22K07976
[Presentation] 肝内胆管細胞におけるリン脂質ホスファターゼSHIP2の細胞核内機能と発がんへの関与2022
- Author(s)
  藤井裕美子、上小倉佑機、後藤正憲、田中宏樹、岡田陽子、西川祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K07976
[Presentation] 肝内胆管細胞における脂質ホスファターゼ SHIP2 の細胞核への集積2022
- Author(s)
  藤井　裕美子、上小倉　佑機、後藤　正憲、人見　淳一、田中　宏樹、岡田　陽子、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝再生における Myc 依存性、Myc 非依存性の肝細胞増殖機構2021
- Author(s)
  後藤正憲、大塩貴子、山本雅大、藤井裕美子、田中宏樹、上小倉佑機、孟玲童、岡田陽子、西川祐司
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Targeting effect of the autologous platelet-based drug delivery system on hepatocellular carcinoma2021
- Author(s)
  Hiroki Tanaka , Kie Horioka , Masanori Goto , Junichi Hitomi , Yumiko Fujii , Yuki Kamikokura , Lingtong Meng , Katsuhiro Ogawa , Yuji Nishikawa
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 自己血小板によるドラッグデリバリーシステム―肝癌・血小板相互作用を利用した新たな治療戦略―2021
- Author(s)
  田中　宏樹、堀岡　希衣、後藤正憲、人見淳一、藤井　裕美子、上小倉　佑機、孟　玲童、小川　勝洋、西川　祐司
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス慢性肝傷害に伴う Myc に依存しない肝細胞増殖メカニズム2021
- Author(s)
  後藤正憲、大塩貴子、山本雅大、藤井裕美子、上小倉佑機、孟玲童、岡田陽子、西川祐司
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 非アルコール性脂肪肝炎の進展における門脈循環障害の意義2021
- Author(s)
  西川祐司、孟玲童、後藤正憲、田中宏樹、上小倉佑機、藤井裕美子、岡田陽子、古川博之
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] p53ノックアウトマウス肝細胞のin vitro形質転換による胆管癌および混合型肝癌細胞株の樹立2020
- Author(s)
  上小倉佑機、後藤正憲、人見淳一、藤井裕美子、田中宏樹、渡邉賢二、大塩貴子、山本雅大、孟玲童、岡田陽子、西川祐司
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] ストレスキナーゼ MKK7の肝傷害後の修復における役割：ウロキナーゼ型プラスミノーゲンアクティベーター活性化の関与2020
- Author(s)
  西川祐司、大塩貴子、山本雅大、藤井清永、辛氷、渡邉賢二、後藤正憲、岡田陽子、鈴木聡、Penninger Josef、仁科博史
- Organizer
  第27回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 非アルコール性脂肪性肝疾患の進展に対する門脈循環障害の影響2020
- Author(s)
  孟玲童，後藤正憲，上小倉佑機，田中宏樹，藤井裕美子，人見淳一，岡田陽子，西川祐司
- Organizer
  第53回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 非アルコール性脂肪性肝疾患の進展に対する門脈循環障害の影響2020
- Author(s)
  孟玲童、後藤正憲、上小倉佑機、藤井裕美子、人見淳一、岡田陽子、西川祐司
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝再生におけるMyc依存性および非依存性肝細胞増殖メカニズムの検討2020
- Author(s)
  後藤正憲，大塩貴子，山本雅大，人見淳一，藤井裕美子，上小倉佑機，孟玲童，岡田陽子，西川祐司
- Organizer
  第53回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 腫瘍・血小板相互作用を利用した肝癌に対する新規治療法2020
- Author(s)
  田中宏樹，堀岡希衣，後藤正憲，人見淳一，藤井裕美子，上小倉佑機，孟玲童，小川勝洋，西川祐司
- Organizer
  第122回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Helicobacter pylori CagA interacts with the lipid phosphatase SHIP2 to increase its delivery into gastric cells2020
- Author(s)
  Yumiko Fujii, Naoko Kamiya, Masanori Hatakeyama
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08436
[Presentation] マウス肝再生におけるMyc依存性および非依存性肝細胞増殖メカニズム2020
- Author(s)
  後藤正憲、大塩貴子、山本雅大、人見淳一、藤井裕美子、上小倉佑機、孟玲童、岡田陽子、西川祐司
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] p53欠損マウス肝細胞のin vitro形質転換：肝内移植で形成される腫瘍の表現型と間質の状態変化の関連2020
- Author(s)
  上小倉佑機，後藤正憲，人見淳一，藤井裕美子，田中宏樹，渡邉賢二，大塩貴子，山本雅大，孟玲童，岡田陽子，西川祐司
- Organizer
  第122回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝腫瘍における胎児期・新生児期遺伝子の発現：癌遺伝子活性に伴うエピゲノム変化2019
- Author(s)
  西川祐司，渡邉賢二，山本雅大，辛氷，大塩貴子，後藤正憲，藤井清永，劉洋，岡田陽子，川博之
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 成熟マウス肝細胞のin vitro形質転換による同所移植可能な胆管癌モデルの開発2019
- Author(s)
  上小倉佑機、後藤正憲、渡邉賢二、大塩貴子、山本雅大、人見淳一、藤井裕美子、孟玲童、岡田陽子、西川祐司
- Organizer
  第16回日本病理学会カンファレンス
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] A novel binding partner for Helicobacter pylori CagA in gastric epithelial cells2018
- Author(s)
  Yumiko Fujii and Masanori Hatakeyama
- Organizer
  The 5th Symposium Max Planck-The University of Tokyo Center for Integrative Inflammalogy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15926
[Presentation] Helicobacter pylori CagA-induced alterations of E-cadherin modifications2018
- Author(s)
  Yumiko Fujii and Masanori Hatakeyama
- Organizer
  The 37th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15926
[Presentation] Spasmolytic polypeptide expressing metaplasia (SPEM) induced in mouse stomach by Helicobacter pylori CagA2014
- Author(s)
  柳谷公平、藤井裕美子、神田浩明、畠山昌則
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26860495

1. Nishikawa Yuji (90208166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
2. 後藤正憲 (00432203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
3. 田中宏樹 (70596155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
4. 人見淳一 (40568664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. 鈴木聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 山本雅大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujii Yumiko 藤井 裕美子

FUJII Yumiko 藤井 裕美子

FUJII YUMIKO 藤井 裕美子

Research Projects

Research Products

Co-Researchers

胆管上皮細胞におけるSHIP2脂質ホスファターゼの核内機能とその発がんへの関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the phosphatase that is a novel binding target for the Helicobacter pylori virulence factor CagA in the host cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms determining the wide spectrum of hepatocytic tumors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Helicobacter pylori CagA-induced dephosphorylation of E-cadherin and its involvement in carcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of gastric carcinogenesis through restricted dedifferentiation by Helicobacter pylori CagAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatocyte MKK7 Contributes to Restoration of the Liver Parenchyma Following Injury2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肝内胆管細胞における脂質ホスファターゼSHIP2の核内機能2023

Author(s)

Organizer

Data Source

[Presentation] 肝内胆管細胞における脂質ホスファターゼSHIP2の細胞核内機能2023

Author(s)

Organizer

Data Source

[Presentation] 血小板由来微小胞による肝腫瘍細胞の生存能促進2022

Author(s)

Organizer

Data Source

[Presentation] 慢性肝障害から発生する肝発癌におけるエピゲノム異常2022

Author(s)

Fujii Yumiko 藤井裕美子

FUJII Yumiko 藤井裕美子

FUJII YUMIKO 藤井裕美子

[Presentation] 活性型 AKT と YAP で誘導したマウス胆管癌表現型に対する Myc または Mycn の影響2022

[Presentation] ストレスキナーゼ MKK7の肝傷害後の修復における役割：ウロキナーゼ型プラスミノーゲンアクティベーター活性化の関与2020