Tada Mikiko 多田美紀子

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TADA Mikiko 多田美紀子

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Researcher Number	30722467
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 客員講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 横浜市立大学, 医学研究科, 客員講師 2018 – 2021: 横浜市立大学, 医学部, 助教 2014 – 2017: 横浜市立大学, 附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Nerve anatomy/Neuropathology Except Principal Investigator Neurology / Basic Section 52020:Neurology-related
Keywords	Principal Investigator ALS / SALS / DEAD box RNA helicase / DDX17 / FTLD / RNA結合タンパク質 / 非膜オルガネラ / DDX5 / Dead box RNA helicase / 孤発性ALS … More / DEAD box protein / TDP-43 / 脳神経疾患 / 小胞体 / RNA代謝異常 / MATR3 / TDP43 / ポリグルタミン病 / polyglutamine / matrin3 … More Except Principal Investigator ポリグルタミン病 / てんかん / 自己免疫性脳炎 / 辺縁系脳炎 / 扁桃体腫大 / 側頭葉てんかん / 活性酸素 / 尿酸トランスポーター / 酸化ストレス / 尿酸 / 多系統萎縮症 / 核内封入体 / RNA結合タンパク / PCBP / カルシウムチャネル / カルシウムシグナリング Less

Analysis of pathological dynamics of membrane-less organelles in SALSPrincipal Investigator
- Principal Investigator
  
  多田美紀子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Yokohama City University
扁桃体腫大を伴う側頭葉てんかんの病態背景の解明と新規治療法の開発
- Principal Investigator
  
  國井美紗子
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Yokohama City University
DEAD box RNA helicases are involved in sporadic ALS pathologyPrincipal Investigator
- Principal Investigator
  
  TADA Mikiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Yokohama City University
Study of pathogenesis caused by hypouricemia in multiple system atrophy
- Principal Investigator
  
  KOYANO Shigeru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Yokohama City University
Elucidation of abnormal accumulation of DDX17 in motor neuron of ALSPrincipal Investigator
- Principal Investigator
  
  Tada Mikiko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Yokohama City University
Analysis of polyglutamine aggregation protein in ALS/FTLDPrincipal Investigator
- Principal Investigator
  
  TADA Mikiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Yokohama City University
Calcium-signaling abnormality of polyglutamine diseases
- Principal Investigator
  
  KOYANO Shigeru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Yokohama City University
Analysis of RNA binding proteins in polyglutamine disease
- Principal Investigator
  
  TANAKA Fumiaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Yokohama City University

All 2022 2021 2020 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 神経内科Clinical Question & Pearls 認知症2017
- Author(s)
  多田美紀子、田中章景
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K18367
[Journal Article] Inhibition of Crmp1 phosphorylation at Ser522 ameliorates motor function and neuronal pathology in amyotrophic lateral sclerosis model mice2022
- Author(s)
  Asano Tetsuya、Nakamura Haruko、Kawamoto Yuko、Tada Mikiko、Kimura Yayoi、Takano Hiroshi、Yao Ryoji、Saito Hiroya、Ikeda Takuya、Komiya Hiroyasu、Kubota Shun、Hashiguchi Shunta、Takahashi Keita、Kunii Misako、Tanaka Kenichi、Goshima Yoshio、Nakamura Fumio、Takeuchi Hideyuki、Doi Hiroshi、Tanaka Fumiaki
- Journal Title
  
  eneuro
  
  Volume: - Issue: 3 Pages: 0133-22
- DOI
  10.1523/eneuro.0133-22.2022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07419, KAKENHI-PROJECT-21K07298, KAKENHI-PROJECT-21K07465, KAKENHI-PROJECT-18K15457
[Journal Article] Matrin 3 Is a Component of Neuronal Cytoplasmic Inclusions of Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis2018
- Author(s)
  Tada Mikiko、Doi Hiroshi、Koyano Shigeru、Kubota Shun、Fukai Ryoko、Hashiguchi Shunta、Hayashi Noriko、Kawamoto Yuko、Kunii Misako、Tanaka Kenichi、Takahashi Keita、Ogawa Yuki、Iwata Ryo、Yamanaka Shoji、Takeuchi Hideyuki、Tanaka Fumiaki
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 188 Issue: 2 Pages: 507-514
- DOI
  10.1016/j.ajpath.2017.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14956, KAKENHI-PROJECT-17K16128, KAKENHI-PROJECT-15K09344
[Presentation] RNA helicases DDX5 and DDX17 are involved in sporadic ALS pathology.2021
- Author(s)
  Mikiko Tada, Hiroshi Doi, Shingo Ikeda, Shunta Hashiguchi, Keita Takahashi, Misako Kunii, Kenichi Tanaka, Shigeru Koyano, Hideyuki Takeuchi, Fumiaki Tanaka
- Organizer
  62nd Annual Meeting of Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-19K07845
[Presentation] DDX5 accumulates in neuronal cytoplasmic inclusions with TDP-43 in SALS.2020
- Author(s)
  Mikiko Tada，Hiroshi Doi，Shingo Ikeda，Shunta Hashiguchi，Atsuko Katsumoto，Misako Kunii，Keita Takahashi，Koyano Shigeru, Hideyuki Takeuchi, Fumiaki Tanaka
- Organizer
  第61回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K07845
[Presentation] DDX5 accumulates in neuronal cytoplasmic inclusions with TDP-43 in SALS.2020
- Author(s)
  Mikiko Tada， Hiroshi Doi， Shingo Ikeda， Shunta Hashiguchi， Atsuko Katsumoto， Misako Kunii， Keita Takahashi， Koyano Shigeru， Hideyuki Takeuchi， Fumiaki Tanaka
- Organizer
  61st Annual Meeting of the Japanese Society of Neurology, Okayama, 2020,5.
- Data Source
  KAKENHI-PROJECT-19K07845
[Presentation] DDX17 accumulates in endoplasmic reticulum of motor neurons in sporadic ALS2018
- Author(s)
  M. Tada, H. Doi, K. Tanaka, M. Kunii, K. Takahashi, H. Takeuchi, S. Koyano, F. Tanaka
- Organizer
  59th annual meeting of the Japanese society of neurology
- Data Source
  KAKENHI-PROJECT-17K14956
[Presentation] DDX17 accumulates in endoplasmic reticulum of motor neurons in sporadic ALS2018
- Author(s)
  多田美紀子、土井宏、田中健一、國井美紗子、高橋慶太、竹内英之、児矢野繁、田中章景
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K14956
[Presentation] 四肢筋力低下で発症したMcLeod症候群の55歳男性例2017
- Author(s)
  多賀須むつき,古宮裕泰,多田美紀子,植松絵里,田中健一,上木英人,児矢野繁,田中章景
- Organizer
  第220回日本神経学会関東・甲信越地方会
- Place of Presentation
  砂防会館（東京都）
- Year and Date
  2017-03-04
- Data Source
  KAKENHI-PROJECT-15K18367
[Presentation] IgG4関連ニューロパチーと鑑別を要した家族性アミロイドポリニューロパチー(ATTR-FAP)の71歳男性例2016
- Author(s)
  古宮裕泰, 多田美紀子, 石戸淳一, 多賀須むつき, 田中健一, 上木英人, 児矢野繁, 田中章景
- Organizer
  第218回日本神経学会関東・甲信越地方会
- Place of Presentation
  砂防会館（東京都）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-15K18367
[Presentation] RNF213多型を認め、中大脳動脈領域に広範囲の脳梗塞を生じた39歳男性例2016
- Author(s)
  浅野敬一郎, 三宅綾子, 中江啓晴, 田中健一, 多田美紀子, 土井宏, 児矢野繁, 田中章景
- Organizer
  第217回日本神経学会関東・甲信越地方会
- Place of Presentation
  砂防会館（東京都）
- Year and Date
  2016-06-04
- Data Source
  KAKENHI-PROJECT-15K18367
[Presentation] Matrin 3 is a component of neuronal cytoplasmic inclusion of motor neuron in SALS2015
- Author(s)
  Mikiko Tada, Hiroshi Doi, Shigeru Koyano, Fumiaki Tanaka
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15K18367
[Presentation] SCA2病変におけるTDP-43細胞内局在2015
- Author(s)
  児矢野繁、多田美紀子、柳下三郎、内原俊記、田中章景
- Organizer
  第56回日本神経病理学会総会
- Place of Presentation
  九州大学医学部百年講堂(福岡県福岡市東区)
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-26670445
[Presentation] 孤発性筋萎縮性側索硬化症におけるMatrin3の病理学的検討2015
- Author(s)
  多田美紀子,土井宏,児矢野繁,田中章景
- Organizer
  第56回日本神経病理学会総会
- Place of Presentation
  九州大学医学部百年講堂（福岡県福岡市）
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-15K18367
[Presentation] 孤発性筋萎縮性側索硬化症におけるMatrin3の病理学的検討2015
- Author(s)
  多田美紀子、土井宏、児矢野繁、田中章景
- Organizer
  第56回日本神経病理学会総会
- Place of Presentation
  九州大学医学部百年講堂(福岡県福岡市東区)
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-26670445

1. TANAKA Fumiaki (30378012)

# of Collaborated Projects: 8 results

# of Collaborated Products: 15 results
2. DOI Hiroshi (10326035)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
3. KOYANO Shigeru (50315818)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
4. 竹内英之 (30362213)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. 國井美紗子 (80725200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 東山雄一 (10722449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tada Mikiko 多田 美紀子

TADA Mikiko 多田 美紀子

Research Projects

Research Products

Co-Researchers

Analysis of pathological dynamics of membrane-less organelles in SALSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

扁桃体腫大を伴う側頭葉てんかんの病態背景の解明と新規治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DEAD box RNA helicases are involved in sporadic ALS pathologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of pathogenesis caused by hypouricemia in multiple system atrophy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of abnormal accumulation of DDX17 in motor neuron of ALSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of polyglutamine aggregation protein in ALS/FTLDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Calcium-signaling abnormality of polyglutamine diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of RNA binding proteins in polyglutamine disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 神経内科Clinical Question & Pearls 認知症2017

Author(s)

Publisher

Data Source

[Journal Article] Inhibition of Crmp1 phosphorylation at Ser522 ameliorates motor function and neuronal pathology in amyotrophic lateral sclerosis model mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Matrin 3 Is a Component of Neuronal Cytoplasmic Inclusions of Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] RNA helicases DDX5 and DDX17 are involved in sporadic ALS pathology.2021

Author(s)

Organizer

Data Source

[Presentation] DDX5 accumulates in neuronal cytoplasmic inclusions with TDP-43 in SALS.2020

Author(s)

Organizer

Data Source

[Presentation] DDX5 accumulates in neuronal cytoplasmic inclusions with TDP-43 in SALS.2020

Author(s)

Organizer

Data Source

[Presentation] DDX17 accumulates in endoplasmic reticulum of motor neurons in sporadic ALS2018

Tada Mikiko 多田美紀子

TADA Mikiko 多田美紀子