Maruyama Junichi 丸山順一

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MARUYAMA Junichi 丸山順一

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Researcher Number	30723639
Other IDs
Affiliation (Current)	2022: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 助教
Affiliation (based on the past Project Information) *help	2018 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2016: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2014 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator General medical chemistry
Keywords	Principal Investigator DNA損傷修復 / 肺線維症 / 肺癌 / 癌転移 / 特発性肺線維症 / DCLK1 / NF-κB / 肺がん / DNA修復 Except Principal Investigator シグナル伝達 … More / 腫瘍抑制 / がん / 筋委縮 / 線維症 / ケミカルバイオロジー / フェイルセーフ / RASSF / 翻訳後修飾 Less

Functional analysis of DCLK1 in pulmonary cancer associated with IPFPrincipal Investigator
- Principal Investigator
  
  MARUYAMA Junichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of the molecular pathology of frequently-accompanied pulmonary cancer in fibrotic lungPrincipal Investigator
- Principal Investigator
  
  Maruyama Junichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Study on the tumor suppressor Hippo pathway and RASSF proteins
- Principal Investigator
  
  Hata Yutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Analysis of tumor suppressors RASSF3 and RASSF6
- Principal Investigator
  
  Iwasa Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University

All 2021 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Doublecortin-like kinase 1 expression is induced by alternative NF-κB signaling in human lung cancer cells2021
- Author(s)
  Yuxiong Lu, Junichi Maruyama, Haruhiko Sugimura and Yutaka Hata
- Journal Title
  
  J. med. dent. sci.
  
  Volume: 68 Issue: 0 Pages: 39-48
- DOI
  10.11480/jmds.680005
- NAID
  130007995188
- ISSN
  1342-8810, 2185-9132
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15059
[Journal Article] Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability2018
- Author(s)
  Lu Yuxiong、Maruyama Junichi、Kuwata Keiko、Fukuda Hiroyuki、Iwasa Hiroaki、Arimoto-Matsuzaki Kyoko、Sugimura Haruhiko、Hata Yutaka
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 16 Pages: 130-137
- DOI
  10.1016/j.bbrep.2018.10.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08624, KAKENHI-PROJECT-18K15059, KAKENHI-PROJECT-16K19029
[Journal Article] Domain analysis of Ras-association domain family member 6 upon interaction with MDM2.2017
- Author(s)
  Sarkar A, Iwasa H, Hossain S, Xu X, Sawada T, Shimizu T, Maruyama J, Arimoto-Matsuzaki K, Hata Y.
- Journal Title
  
  FEBS Lett.
  
  Volume: 591 Pages: 260-272
- DOI
  10.1002/1873-3468.12551
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26460359, KAKENHI-PROJECT-26860185, KAKENHI-PROJECT-16K19029
[Journal Article] Validation of the chemical compound library screening for TAZ inhibitors by use of　green fluorescence protein-fused TAZ2016
- Author(s)
  Nagashima S, Maruyama J, Kawano S, Iwasa H, Nakagawa K, Ishigami-Yuasa M, Kagechika H, Nishina H, Hata Y.
- Journal Title
  
  Cancer science
  
  Volume: - Pages: 791-802
- DOI
  10.1111/cas.12936
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460359, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-26860185
[Journal Article] ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.2016
- Author(s)
  Maruyama J, Kobayashi Y, Umeda T, Vandewalle A, Takeda K, Ichijo H, Naguro I.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 95-104
- DOI
  10.1038/srep18710
- NAID
  120006987229
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860185, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-26293016, KAKENHI-PLANNED-26114009
[Journal Article] A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.2015
- Author(s)
  Kawano S, Maruyama J, Nagashima S, Inami K, Qiu W, Iwasa H, Nakagawa K, Ishigami-Yuasa M, Kagechika H, Nishina H, Hata Y.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 158 Pages: 413-23
- DOI
  10.1093/jb/mvv051
- NAID
  40020646985
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460359, KAKENHI-PROJECT-26860185, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293061
[Journal Article] A new cell-based assay to evaluate myogenesis in mouse myoblast C2C12 cells.2015
- Author(s)
  Kodaka, M.; Yang, Z.; Nakagawa, K.; Maruyama, J.; Xu, X.; Sarkar, A.; Ichimura, A.; Nasu, Y.; Ozawa, T.; Iwasa, H.; Ishigami-Yuasa, M.; Ito, S.; Kagechika, H.; Hata, Y.
- Journal Title
  
  Exp. Cell Res
  
  Volume: 336 Pages: 171-181
- DOI
  10.1016/j.yexcr.2015.06.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670052, KAKENHI-PROJECT-26860185, KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26220805
[Journal Article] Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in the muscle injury model.2014
- Author(s)
  Yang, Z. Y.; Nakagawa, K.; Sarkar, A.; Maruyama, J.; Iwasa, H.; Bao, Y. J.; Ishigami-Yuasa, M.; Ito, S.; Kagechika, H.; Hata, S.; Nishina, H.; Abe, S.; Kitagawa, M.; Hata, Y.
- Journal Title
  
  Mol. Cell Biol.
  
  Volume: 34 Pages: 1607-1621
- DOI
  10.1128/mcb.01346-13
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22136013, KAKENHI-PROJECT-23790325, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-26293061, KAKENHI-PROJECT-26860185
[Presentation] Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability.2019
- Author(s)
  Junichi Maruyama, Haruhiko Sugimura and Yutaka Hata
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15059
[Presentation] 新規に同定したYAP1活性化化合物は多発性骨髄腫細胞においてYAP1-p73経路依存的な細胞死を誘導する2016
- Author(s)
  丸山順一、江欣亮、岩佐宏晃、湯浅（石上）磨里、影近弘之、仁科博史、畑裕
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26860185
[Presentation] 新規に同定したYAP1活性化化合物は多発性骨髄腫に置いてYAP1-p73経路依存的な細胞死を誘導する2016
- Author(s)
  丸山順一、江欣亮、岩佐宏晃、湯浅―石上磨里、影近弘之、仁科博史、畑裕
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜パシフィコ
- Data Source
  KAKENHI-PROJECT-26293061
[Presentation] 細胞内局在を指標とする探索系による転写共役因子（TAZ）抑制剤探索の有効性の検証2016
- Author(s)
  長島俊太、丸山順一、湯浅―石上磨里、影近弘之、仁科博史、畑裕
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜パシフィコ
- Data Source
  KAKENHI-PROJECT-26293061

1. Iwasa Hiroaki (70582188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. Hata Yutaka (80313237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. MATSUZAKI Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 仁科博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 影近弘之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 小澤岳昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中川健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 一條秀憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 名黒功

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 武田弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maruyama Junichi 丸山 順一

MARUYAMA Junichi 丸山 順一

Research Projects

Research Products

Co-Researchers

Functional analysis of DCLK1 in pulmonary cancer associated with IPFPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the molecular pathology of frequently-accompanied pulmonary cancer in fibrotic lungPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the tumor suppressor Hippo pathway and RASSF proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of tumor suppressors RASSF3 and RASSF6

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Doublecortin-like kinase 1 expression is induced by alternative NF-κB signaling in human lung cancer cells2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Domain analysis of Ras-association domain family member 6 upon interaction with MDM2.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Validation of the chemical compound library screening for TAZ inhibitors by use of green fluorescence protein-fused TAZ2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A new cell-based assay to evaluate myogenesis in mouse myoblast C2C12 cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in the muscle injury model.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability.2019

Author(s)

Organizer

Data Source

[Presentation] 新規に同定したYAP1活性化化合物は多発性骨髄腫細胞においてYAP1-p73経路依存的な細胞死を誘導する2016

Author(s)

Maruyama Junichi 丸山順一

MARUYAMA Junichi 丸山順一

[Journal Article] Validation of the chemical compound library screening for TAZ inhibitors by use of　green fluorescence protein-fused TAZ2016