Yasukochi Atsushi 安河内篤

Researcher Number	30724968
Affiliation (Current)	2026: 九州大学, 歯学研究院, 共同研究員
Affiliation (based on the past Project Information) *help	2026: 九州大学, 歯学研究院, 共同研究員 2016 – 2024: 九州大学, 歯学研究院, 共同研究員 2014 – 2015: 九州大学, 歯学研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Keywords	Principal Investigator 口腔癌 / BP180 / ヘミデスモソーム / 粘膜類天疱瘡 / 歯学 / miRNA / P53 / がん / p53 / 非コードRNA / 浸潤 / 口腔外科学

口腔癌における17型コラーゲンの発現制御と機能解析Principal Investigator
- Principal Investigator
  
  安河内篤
- Project Period (FY)
  2026 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kyushu University
口腔癌におけるヘミデスモソーム蛋白BP180の発現制御と浸潤プロセスへの関与Principal Investigator
- Principal Investigator
  
  安河内篤
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kyushu University
Molecular mechanism of oral cancer invation focusing on hemidesmosome structurePrincipal Investigator
- Principal Investigator
  
  Yasukochi Atsushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kyushu University
Development of the novel diagnostic method on mucous membrane pemphigoid using salivaPrincipal Investigator
- Principal Investigator
  
  YASUKOCHI Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu University
A study of novel BP180 C-terminal domain ELISA on mucous membrane pemphigoidPrincipal Investigator
- Principal Investigator
  
  Yasukochi Atsushi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu University

All 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] 4-Octyl Itaconate Attenuates Cell Proliferation by Cellular Senescence <i>via</i> Glutathione Metabolism Disorders and Mitochondrial Dysfunction in Melanoma2025
- Author(s)
  Hayashi Yoshikazu、Saeki Ayaka、Yoshimoto Shohei、Yano Ena、Yasukochi Atsushi、Kimura Soi、Utsunomiya Tomoe、Minami Kento、Aso Yuji、Hatakeyama Yuji、Lo Yi-Chen、Hirata Masato、Jimi Eijiro、Kawakubo-Yasukochi Tomoyo
- Journal Title
  
  Antioxidants & Redox Signaling
  
  Volume: in press Issue: 10-12 Pages: 547-565
- DOI
  10.1089/ars.2024.0629
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19721, KAKENHI-PROJECT-22K09914, KAKENHI-PROJECT-22K10173, KAKENHI-PROJECT-23K09133, KAKENHI-PROJECT-23K09161, KAKENHI-PROJECT-24K19842, KAKENHI-PROJECT-24KJ1774, KAKENHI-PROJECT-22KK0263
[Journal Article] Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p2023
- Author(s)
  1.Hayashi Y, Kimura S, Yano E, Yoshimoto S, Saeki A, Yasukochi A, Hatakeyama Y, Moriyama M, Nakamura S, Jimi E, Kawakubo-Yasukochi T.
- Journal Title
  
  Biochim Biophys Acta Mol Cell Res
  
  Volume: 1870(2) Issue: 2 Pages: 119404-119404
- DOI
  10.1016/j.bbamcr.2022.119404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09914, KAKENHI-PROJECT-22K10173, KAKENHI-PROJECT-22K19631, KAKENHI-PROJECT-22K17003, KAKENHI-PROJECT-20K17381, KAKENHI-PROJECT-22K18401, KAKENHI-PROJECT-19K22723, KAKENHI-PROJECT-23KK0164, KAKENHI-PROJECT-21K10075
[Journal Article] Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice2021
- Author(s)
  Kawakubo-Yasukochi Tomoyo、Yano Ena、Kimura Soi、Nishinakagawa Takuya、Mizokami Akiko、Hayashi Yoshikazu、Hatakeyama Yuji、Ohe Kenji、Yasukochi Atsushi、Nakamura Seiji、Jimi Eijiro、Hirata Masato
- Journal Title
  
  Molecular Metabolism
  
  Volume: 54 Pages: 101360-101360
- DOI
  10.1016/j.molmet.2021.101360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-19K10269, KAKENHI-PROJECT-20K23114, KAKENHI-PROJECT-20H03854
[Journal Article] Maternal folic acid depletion during early pregnancy increases sensitivity to squamous tumor formation in the offspring in mice2019
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Ohe K, Yasukochi A, Ozaki Y, Hazekawa M, Nishinakagawa T, Ono K, Nakamura S, Nakashima M.
- Journal Title
  
  J Dev Orig Health Dis
  
  Volume: 10(6) Issue: 6 Pages: 683-691
- DOI
  10.1017/s2040174419000217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-19K10269
[Journal Article] Regulation of collagen type XVII expression by miR203a-3p in oral squamous cell carcinoma cells2019
- Author(s)
  Yasukochi A, Kawakubo-Yasukochi T, Morioka M, Hazekawa M, Nishinakagawa T, Ono K, Nakashima M, Nakamura S.
- Journal Title
  
  J Biochem
  
  Volume: in press Issue: 2 Pages: 163-173
- DOI
  10.1093/jb/mvz024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11496, KAKENHI-PROJECT-16K20585, KAKENHI-PROJECT-19K10052, KAKENHI-PROJECT-19K10269
[Journal Article] miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment.2018
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Hazekawa M, Yasukochi A, Nishinakagawa T, Ono K, Kawano S, Nakamura S, Nakashima M.
- Journal Title
  
  Mol Carcinog
  
  Volume: 57 Issue: 2 Pages: 295-302
- DOI
  10.1002/mc.22744
- NAID
  120006900039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11496, KAKENHI-PROJECT-16K20585
[Journal Article] Clinical and Immunological Study of 332 Japanese Patients Tentatively Diagnosed with Anti-BP180-type Mucous Membrane Pemphigoid: A Novel BP180 C-terminal Domain Enzyme-linked Immunosorbent Assay.2016
- Author(s)
  Yasukochi A, Teye K, Ishii N, Hashimoto T.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: 0 Pages: 0-0
- DOI
  10.2340/00015555-2407
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861762, KAKENHI-PROJECT-16K20585
[Journal Article] Granular C3 Dermatosis.2016
- Author(s)
  Hashimoto T, Tsuruta D, Yasukochi A, Imanishi H, Sekine H, Fujita T, Wanibuchi H, Gi M, Kárpáti S, Sitaru C, Zone JJ, Endo D, Abe S, Nishino T, Koji T, Ishii N.
- Journal Title
  
  Acta Derm Venereol
  
  Volume: 00 Pages: 00-00
- DOI
  10.2340/00015555-2379
- NAID
  120006987674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670478, KAKENHI-PROJECT-26861762, KAKENHI-PROJECT-16H05813, KAKENHI-PROJECT-26340042, KAKENHI-PROJECT-16K10180, KAKENHI-PROJECT-16K18979, KAKENHI-PROJECT-16K20585
[Journal Article] Anti-BP180-type oral mucous membrane pemphigoid reactive to both NC16a and C-terminal domains.2015
- Author(s)
  Uchiyama M, Mitsuhashi Y, Tsuboi R, Ishii N, Hayakawa T, Yasukochi A, Hashimoto T.
- Journal Title
  
  Indian J Dermatol Venereol Leprol.
  
  Volume: 81 Issue: 6 Pages: 637-639
- DOI
  10.4103/0378-6323.168330
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861762
[Journal Article] Case of subepidermal autoimmune bullous disease with psoriasis vulgaris reacting to both BP180 C-terminal domain and laminin gamma-1.2015
- Author(s)
  Ishida S, Takahashi K, Kanaoka M, Okawa T, Tateishi C, Yasukochi A, Ishii N, Li X, Hashimoto T, Aihara M.
- Journal Title
  
  J Dermatol.
  
  Volume: 42 Issue: 4 Pages: 391-393
- DOI
  10.1111/1346-8138.12801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861762
[Journal Article] Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.2014
- Author(s)
  Goto S, Ozaki Y, Suzumori N, Yasukochi A, Kawakubo T, Furuno T, Nakanishi M, Yamamoto K, Sugiura-Ogasawara M.
- Journal Title
  
  Mol Hum Reprod.
  
  Volume: 20 Issue: 5 Pages: 454-462
- DOI
  10.1093/molehr/gau008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592478, KAKENHI-PROJECT-24592479, KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-26861762
[Journal Article] A case of concurrent anti-laminin γ1 pemphigoid and anti-laminin 332-type mucous membrane pemphigoid2014
- Author(s)
  Li X, Qian H, Ishii N, Yamaya M, Fukuda H, Mukai H, Hirako Y, and Hashimoto T
- Journal Title
  
  Br J Dermatol
  
  Volume: 171 Issue: 6 Pages: 1555-1557
- DOI
  10.1111/bjd.13113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659547, KAKENHI-PROJECT-26670527, KAKENHI-PROJECT-26861762
[Journal Article] A case of lichen planus pemphigoides with autoantibodies to the NC16a and C-terminal domains of BP180 and to desmoglein-1.2014
- Author(s)
  Sekiya A, Kodera M, Yamaoka T, Iwata Y, Usuda T, Ohzono A, Yasukochi A, Koga H, Ishii N, Hashimoto T.
- Journal Title
  
  Br J Dermatol.
  
  Volume: 171 Issue: 5 Pages: 1230-1235
- DOI
  10.1111/bjd.13097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861762
[Journal Article] Immunological and Statistical Studies of Anti-BP180 Antibodies in Paraneoplastic Pemphigus2014
- Author(s)
  Tsuchisaka A, Kawano H, Yasukochi A, Teye K, Ishii N, Koga H, Sogame R, Ohzono A, Krol RP, Kawakami T, Furumura M, Ohata C, Li X, Hashimoto T
- Journal Title
  
  J Invest Dermatol
  
  Volume: 134 Issue: 8 Pages: 2283-2287
- DOI
  10.1038/jid.2014.151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659534, KAKENHI-PROJECT-25461678, KAKENHI-PROJECT-26861762
[Journal Article] Cathepsin E in mammary gland: Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.2013
- Author(s)
  Tomoyo Kawakubo, Atsushi Yasukochi, Tatsuya Toyama, Satoru Takahashi, Kuniaki Okamoto, Takayuki Tsukuba, Seiji Nakamura, Yasuhiko Ozaki, Koichi Nishigaki, Hiroko Yamashita, and Kenji Yamamoto
- Journal Title
  
  Carcinogenesis
  
  Volume: 00 Issue: 3 Pages: 1-13
- DOI
  10.1093/carcin/bgt373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24240059, KAKENHI-PROJECT-24592479, KAKENHI-PROJECT-24659840, KAKENHI-PROJECT-25293383, KAKENHI-PROJECT-25462920, KAKENHI-PROJECT-26670906, KAKENHI-PROJECT-26861554, KAKENHI-PROJECT-26861762
[Presentation] Pathophysiological role of Id4 for salivary gland homeostasis and IgG4-related diseases2024
- Author(s)
  Yoshikazu Hayashi, Soi Kimura, Ena Yano, Shohei Yoshimoto, Ayaka Saeki, Teppei Yasukuni, Atsushi Yasukochi, Yuji Hatakeyama, Masato Hirata, Eijiro Jimi, Tomoyo Kawakubo-Yasukochi
- Organizer
  8th Edition of International Conference on Dentistry and Oral Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10173
[Presentation] antitumor Effect of 4-Octyl Itaconate via Targeting Glutathione Metabolism2024
- Author(s)
  佐伯彩華、林慶和、吉本尚平、安河内篤、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第66回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10173
[Presentation] The role of Id4 in salivary gland homeostasis2024
- Author(s)
  Soi. Kimura, Yoshikazu. Hayashi, Ena. Yano, Shohei. Yoshimoto, Ayaka. Saeki, Atsushi. Yasukochi, Masato. Hirata, Eijiro. Jimi, Tomoyo. Kawakubo-Yasukochi
- Organizer
  The 24th Japan-Korea Joint Seminar on Pharmacology Japan-Korea Joint Session of the 96th Annual Meeting of the Japanese Pharmacological Society
- Data Source
  KAKENHI-PROJECT-22K10173
[Presentation] Maternal high calorie diet during pregnancy induces abnormal hepatic glycogenolysis in the offspring and it is mitigated by osteocalcin2022
- Author(s)
  Kawakubo-Yasukochi T, Yano E, Kimura S, Mizokami A, Hayashi Y, Yasukochi A, Nakamura S, Jimi E, Hirata M.
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K10269
[Presentation] The role of Id4 in salivary gland and its involvement in the pathology of IgG4-related disease2022
- Author(s)
  Kimura S, Hayashi Y, Yano E, Saeki A, Yasukochi A, Moriyama M, Nakamura S, Jimi E, Kawakubo-Yasukochi T
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K10173
[Presentation] 唾液腺におけるId4の役割と病態への関与2022
- Author(s)
  木村宗惟、林慶和、佐伯彩華、安河内篤、中村誠司、自見英治郎、安河内（川久保）友世
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10173
[Presentation] 妊娠母体栄養がもたらす産仔の肝グリコーゲン分解異常とオステオカルシンによる回避2022
- Author(s)
  安河内（川久保）友世、矢野恵奈、木村宗惟、溝上顕子、林慶和、安河内篤、中村誠司、自見英治郎、平田雅人
- Organizer
  第9回日本DOHaD学会
- Data Source
  KAKENHI-PROJECT-22K10173
[Presentation] 口腔扁平上皮癌におけるBP180の発現制御機構2020
- Author(s)
  安河内篤、安河内(川久保)友世、中村誠司
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10269
[Presentation] miR-200c-3pによる口腔扁平上皮癌の浸潤制御機構2019
- Author(s)
  安河内(川久保)友世、森岡政彦、櫨川舞、西中川拓也、安河内篤、中村誠司、中島学
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K10269
[Presentation] miR-200c-3pによる口腔扁平上皮癌の浸潤制御機構2019
- Author(s)
  安河内（川久保）友世、森岡政彦、櫨川舞、西中川拓也、安河内篤、中村誠司、中島学
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K20585
[Presentation] The effect of maternal folic acid deficiency during early pregnancy on the carcinogen sensitivity of offspring in mice2019
- Author(s)
  Kawakubo-Yasukochi T, Morioka M, Yasukochi A, Hazekawa M, Nishinakagawa T, Ono K, Nakamura S, Nakashima M
- Organizer
  The 11th DOHaD World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10269
[Presentation] 妊娠母体の葉酸不足は仔の皮膚および舌において扁平上皮の発癌感受性を増強させる2019
- Author(s)
  安河内(川久保)友世、森岡政彦、安河内篤、櫨川舞、西中川拓也、中村誠司、中島学
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K10269
[Presentation] 口腔扁平上皮癌における BP180 の局在2017
- Author(s)
  安河内篤、森岡政彦、川久保－安河内友世、中島学、中村誠司
- Organizer
  第５９回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K20585
[Presentation] 非コードRNAによる口腔癌の進展抑制2017
- Author(s)
  川久保－安河内友世、森岡政彦、安河内篤、中村誠司、中島学
- Organizer
  第５９回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K20585
[Presentation] The significance of BP180 expression in oral squamous carcinoma cell invasion2017
- Author(s)
  Yasukochi A, Morioka M, Kawakubo-Yasukochi T, Nakashima M, Nakamura S
- Organizer
  The 5th Congress of ASHNO
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2017-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20585
[Presentation] Link of BP180 bullous pemphigoid autoantigen to invasion of oral squamous carcinoma cell2016
- Author(s)
  Yasukochi A, Morioka M, Kawakubo-Yasukochi T, Obayashi K, Nakashima M, Nakamura S
- Organizer
  ANZHNCS Annual Scientific Meeting and the IFHNOS 2016 World Tour
- Place of Presentation
  Auckland, New Zealand
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20585
[Presentation] IgA沈着が主体だった抗BP180型口腔粘膜型類天疱瘡の1例
- Author(s)
  井上智子、矢上晶子、高橋正幸、岩田洋平、石井文人、安河内篤、橋本隆、松永佳世子
- Organizer
  第113回　日本皮膚科学会総会
- Place of Presentation
  岡山
- Year and Date
  2014-05-30 – 2014-06-02
- Data Source
  KAKENHI-PROJECT-26861762

1. KAWAKUBO Tomoyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. Morioka Masahiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. SUGIURA Mayumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. SEKINE Hideharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 木村宗惟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 溝上顕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 平子善章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 西垣功一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 石井文人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 土坂享成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. TEYE KWESI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 橋本隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yasukochi Atsushi 安河内 篤

Research Projects

Research Products

Co-Researchers

口腔癌における17型コラーゲンの発現制御と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

口腔癌におけるヘミデスモソーム蛋白BP180の発現制御と浸潤プロセスへの関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of oral cancer invation focusing on hemidesmosome structurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the novel diagnostic method on mucous membrane pemphigoid using salivaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of novel BP180 C-terminal domain ELISA on mucous membrane pemphigoidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 4-Octyl Itaconate Attenuates Cell Proliferation by Cellular Senescence <i>via</i> Glutathione Metabolism Disorders and Mitochondrial Dysfunction in Melanoma2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Maternal folic acid depletion during early pregnancy increases sensitivity to squamous tumor formation in the offspring in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of collagen type XVII expression by miR203a-3p in oral squamous cell carcinoma cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Clinical and Immunological Study of 332 Japanese Patients Tentatively Diagnosed with Anti-BP180-type Mucous Membrane Pemphigoid: A Novel BP180 C-terminal Domain Enzyme-linked Immunosorbent Assay.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Granular C3 Dermatosis.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Anti-BP180-type oral mucous membrane pemphigoid reactive to both NC16a and C-terminal domains.2015

Author(s)

Journal Title

DOI

Yasukochi Atsushi 安河内篤