Funahashi Nobuaki 舟橋伸昭

… Alternative Names

舟橋伸昭フナハシノブアキ

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Researcher Number	30727491
Affiliation (Current)	2022: 東京工業大学, 生命理工学院, 助教 2022: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所, 技師・研究員
Affiliation (based on the past Project Information) *help	2020: 東京工業大学, 生命理工学院, 研究員 2018: 国立研究開発法人国立国際医療研究センター, その他部局等, 上級研究員 2016 – 2018: 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員 2015: 国立研究開発法人国立国際医療研究センター, その他部局等, その他
Review Section/Research Field	Principal Investigator Applied health science / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 生活習慣病 / DOHaD / エピジェネティクス / 胎盤 / 糖尿病 / DNAメチル化 / 低栄養 / 栄養成分 / AMPK / ビタミンD / 栄養状態

妊娠期ビタミンD摂取量と児の将来の生活習慣病の発症リスクとの関連性の検討Principal Investigator
- Principal Investigator
  
  舟橋伸昭
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Institute of Technology
The molecular mechanism of epigenomic regulation by maternal nutritional status in placenta.Principal Investigator
- Principal Investigator
  
  Funahashi Nobuaki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  National Center for Global Health and Medicine
The investigation of relationship between maternal undernutrition and epigenetic changesPrincipal Investigator
- Principal Investigator
  
  Funahashi Nobuaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  National Center for Global Health and Medicine

All 2020 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] PRC2 Components Maintain DNA Hypermethylation of the Upstream Promoter and Regulate Robo4 Expression in Endothelial Cells2020
- Author(s)
  Izawa Kohei、Shirakura Keisuke、Kakiuchi Koji、Funahashi Nobuaki、Maekawa Naoki、Hino Nobumasa、Tanaka Toru、Doi Takefumi、Okada Yoshiaki
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 43 Issue: 4 Pages: 742-746
- DOI
  10.1248/bpb.b19-01014
- NAID
  130007825307
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19403, KAKENHI-PROJECT-20K11663
[Journal Article] Effects of maternal and fetal choline concentrations on the fetal growth and placental DNA methylation of 12 target genes related to fetal growth, adipogenesis, and energy metabolism2020
- Author(s)
  Nakanishi Misao、Funahashi Nobuaki、Fukuoka Hideoki、Nammo Takao、Sato Yuichi、Yoshihara Hajime、Oishi Hajime、Tanaka Mamoru、Yano Tetsu、Minoura Shigeki、Kato Norihiro、Yasuda Kazuki
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 47 Pages: 734-744
- DOI
  10.1111/jog.14599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11663
[Journal Article] Genome-wide profiling of histone H3K27 acetylation featured fatty acid signalling in pancreatic beta cells in diet-induced obesity in mice2018
- Author(s)
  Nammo T, Udagawa H, Funahashi N, Kawaguchi M, Uebanso T, Hiramoto M, Nishimura W, Yasuda K.
- Journal Title
  
  Diabetologia
  
  Volume: 61 Pages: 2608-2620
- DOI
  10.1007/s00125-018-4735-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09843, KAKENHI-PROJECT-18K06901, KAKENHI-PROJECT-18K08496, KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-17K13237
[Journal Article] A type 2 diabetes-associated SNP in KCNQ1(rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a,　potentially affecting CDKN1C expression. Int J Mol Med.2018
- Author(s)
  Hiramoto M, Udagawa H, Ishibashi N, Takahashi E, Kaburagi Y, Miyazawa K, Funahashi N, Nammo T, Yasuda K.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 41(2) Pages: 717-728
- DOI
  10.3892/ijmm.2017.3273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K13237, KAKENHI-PROJECT-17K08771
[Journal Article] Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: Comparison with hepatitis virus-related carcinogenesis.2017
- Author(s)
  Kuramoto J, Arai E, Tian Y, Funahashi N, Hiramoto M, Nammo T, Nozaki Y, Takahashi Y, Ito N, Shibuya A, Ojima H, Sukeda A, Seki Y, Kasama K, Yasuda K, Kanai Y.
- Journal Title
  
  Carcinogenesis
  
  Volume: 38 Pages: 261-270
- DOI
  10.1093/carcin/bgx005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461352, KAKENHI-PROJECT-15K16537, KAKENHI-PROJECT-16K01850, KAKENHI-PROJECT-16K08720, KAKENHI-PROJECT-16H02472, KAKENHI-PROJECT-17K15668
[Journal Article] Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1.2015
- Author(s)
  Hirota Y, Nakagawa K, Sawada N, Okuda N, Suhara Y, Uchino Y, Kimoto T, Funahashi N, Kamao M, Tsugawa N, Okano T.
- Journal Title
  
  PLoS　One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0125737
- NAID
  130007413127
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860047, KAKENHI-PROJECT-15K16537, KAKENHI-PROJECT-26560072
[Journal Article] Expression of the Robo4 receptor in endothelial cells is regulated by two AP-1 protein complexes.2015
- Author(s)
  Okada Y, Naruse H, Tanaka T, Funahashi N, Regan ER, Yamakawa K, Hino N, Ishimoto K, Doi T, Aird WC.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 467(4) Pages: 987-91
- DOI
  10.1016/j.bbrc.2015.10.029
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16537, KAKENHI-PROJECT-26870346, KAKENHI-PROJECT-26293014
[Journal Article] Demethylation of the MafB promoter in a compromised β-cell model.2015
- Author(s)
  Nishimura W, Ishibashi N, Eto K, Funahashi N, Udagawa H, Miki H, Oe S, Noda Y, Yasuda K.
- Journal Title
  
  J Mol Endocrinol
  
  Volume: 55(1) Pages: 31-40
- DOI
  10.1530/jme-15-0042
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461351, KAKENHI-PROJECT-15K16537
[Journal Article] YY1 positively regulates human UBIAD1 expression.2015
- Author(s)
  Funahashi N, Hirota Y, Nakagawa K, Sawada N, Watanabe M, Suhara Y, Okano T
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: in press Pages: 238-244
- DOI
  10.1016/j.bbrc.2015.03.018
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460085, KAKENHI-PROJECT-26860047, KAKENHI-PROJECT-15K16537
[Presentation] 内臓脂肪組織有意に発現する転写因子Gata5による酸化ストレス防御機構2020
- Author(s)
  宇田川陽秀、舟橋伸昭、南茂隆生、平本正樹、西村渉、今泉美香、植木浩二郎、安田和基
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K11663
[Presentation] ヒトNASH肝で高発現するAKR1B15の発現制御機序および機能解析2018
- Author(s)
  舟橋伸昭、宇田川陽秀、南茂隆生、安田和基
- Organizer
  第5回肝臓と糖尿病・代謝研究会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] ヒトNASH肝で高発現するAKR1B15の発現制御メカニズムおよび機能解析2018
- Author(s)
  舟橋伸昭
- Organizer
  第17回 Diabetes Research Forum in Tokyo
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 肝細胞におけるAKR1B10の発現制御メカニズムの解析2018
- Author(s)
  舟橋伸昭、宇田川陽秀、南茂隆生、安田和基
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] インスリン分泌抑制因子Necab1のGRを介した発現調節機構2018
- Author(s)
  宇田川陽秀、舟橋伸昭、西村　渉、平本正樹、南茂隆生、安田和基
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 高脂肪食にて活性増加する膵島cis調節領域の網羅的検討から見出された結合因子Nuclear respiratory factor 1 (Nrf1) の機能的検討2018
- Author(s)
  南茂隆生、宇田川陽秀、舟橋伸昭、川口美穂、上番増喬、平本正樹、西村渉、安田和基
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 遺伝子cis調節領域の網羅的エピゲノム解析と膵島代償機序に関与する転写因子モチーフの検討2017
- Author(s)
  南茂隆生，宇田川陽秀，舟橋伸昭，川口美穂，上番増喬，平本正樹，西村渉，安田和基
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 児の出生体重，胎盤重量とDNAメチル化状態および遺伝子発現量との関連性の検討2017
- Author(s)
  舟橋伸昭，宇田川陽秀，南茂隆生，中西美紗緒，矢野哲，箕浦茂樹，福岡秀興，安田和基
- Organizer
  第6回日本DOHaD学会学術集会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 内臓脂肪組織優位に発現する転写因子Gata5 の機能解析2017
- Author(s)
  宇田川陽秀，南茂隆生，舟橋伸昭，平本正樹，西村渉，松本健治，関洋介，笠間和典，安田和基
- Organizer
  第38回日本肥満学会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 児の出生体重，胎盤重量とDNAメチル化状態との関連性の検討2017
- Author(s)
  舟橋伸昭，宇田川陽秀，南茂隆生，中西美紗緒，矢野哲，箕浦茂樹，福岡秀興，安田和基
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 高度肥満患者の内臓脂肪組織優位に発現する転写因子Gata5の機能解析2017
- Author(s)
  宇田川陽秀，舟橋伸昭，南茂隆生，平本正樹，西村渉，松本健治，関洋介，笠間和典，安田和基
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K13237
[Presentation] 妊婦栄養状態とDNAメチル化状態との関連性の検討2016
- Author(s)
  舟橋伸昭，宇田川陽秀，南茂隆生，中西美紗緒，矢野哲，箕浦茂樹，福岡秀興，安田和基
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] ゲノム網羅的解析結果を用いた膵島代償機序の検討2016
- Author(s)
  南茂隆生，宇田川陽秀，舟橋伸昭，川口美穂，上番増喬，平本正樹，西村渉，安田和基
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 日本人高度肥満症由来NASH肝のトランスクリプトーム解析2016
- Author(s)
  舟橋伸昭，宇田川陽秀，南茂隆生，上番増喬，西村渉，平本正樹，松本健治，関洋介，笠間和典，安田和基
- Organizer
  第3回肝臓と糖尿病・代謝研究会
- Place of Presentation
  石川県立音楽堂邦楽ホール・交流ホール（石川）
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 脂肪細胞培養上清によるグルココルチコイド受容体を介した膵β細胞機能変化2016
- Author(s)
  宇田川陽秀，舟橋伸昭，西村渉，平本正樹，川口美穂，南茂隆生，安田和基
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 高度肥満患者由来内臓脂肪・皮下脂肪の遺伝子発現の比較解析2016
- Author(s)
  安田和基，宇田川陽秀，南茂隆生，舟橋伸昭，平本正樹，西村渉，松本健治，関洋介，笠間和典
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 高度肥満患者および肥満マウス由来内臓脂肪・皮下脂肪発現遺伝子の比較解析2016
- Author(s)
  宇田川陽秀，南茂隆生，舟橋伸昭，平本正樹，西村渉，松本健治，関洋介，笠間和典，安田和基
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン（東京）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 膵島のゲノム網羅的解析による膵島代償機序/糖尿病発症機序関連因子の同定2015
- Author(s)
  南茂隆生，宇田川陽秀，川口美穂，舟橋伸昭，上番増喬，平本正樹，西村渉，安田和基
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（下関）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 脂肪細胞由来ステロイドホルモンによるGRを介した膵β細胞機能変化2015
- Author(s)
  宇田川陽秀，舟橋伸昭，平本正樹，川口美穂，西村渉，南茂隆生，安田和基
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（下関）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 妊婦低栄養とDNAメチル化状態との関連性の検討へ向けて2015
- Author(s)
  舟橋伸昭,宇田川陽秀,南茂隆生,西村渉,川口美穂,矢野哲,中西美紗緒,箕浦茂樹,福岡秀興,安田和基
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（下関）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 妊婦栄養とエピジェネティクス変化との関連性の検討2015
- Author(s)
  舟橋伸昭
- Organizer
  第12回　Diabetes Research Forum in Tokyo
- Place of Presentation
  パレスホテル東京（東京）
- Year and Date
  2015-10-20
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 高度肥満患者由来の脂肪組織の多層的オミックス解析2015
- Author(s)
  安田和基，宇田川陽秀，南茂隆生，平本正樹，西村渉，上番増喬，舟橋伸昭，金井弥栄，松本健治，斎藤嘉朗，関洋介，笠間和典
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 日本人肥満者由来NASH肝の多層的オミックス解析パネルの構築2015
- Author(s)
  安田和基，南茂隆生，平本正樹，西村渉，宇田川陽秀，上番増喬, 舟橋伸昭，金井弥栄，松本健治，斎藤嘉朗，関洋介，笠間和典
- Organizer
  第2回肝臓と糖尿病・代謝研究会
- Place of Presentation
  シーモールパレス（下関）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 高度肥満患者由来の脂肪組織の多層的オミックス解析2015
- Author(s)
  安田和基，南茂隆生，平本正樹，西村渉，宇田川陽秀，上番増喬, 舟橋伸昭，金井弥栄，松本健治，斎藤嘉朗，関洋介，笠間和典
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（下関）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K16537
[Presentation] 脂肪細胞培養上清による膵β 細胞機能変化2015
- Author(s)
  宇田川陽秀，舟橋伸昭，平本正樹，川口美穂，西村渉，南茂隆生，安田和基
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K16537

1. HINO Nobumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. NISHIMURA Wataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. OKADA Yoshiaki

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# of Collaborated Products: 1 results
4. YASUDA Kazuki

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# of Collaborated Products: 1 results
5. Nammo Takao

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# of Collaborated Products: 3 results
6. ARAI Eri

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# of Collaborated Products: 1 results
7. KANAI Yae

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# of Collaborated Products: 2 results
8. ITO Hidemi

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9. 平本正樹

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10. 廣田佳久

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11. 鎌尾まや

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# of Collaborated Products: 1 results
12. 石本憲司

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# of Collaborated Products: 1 results
13. 土井健史

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14. Aird William

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15. 宮澤啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 中川公恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Funahashi Nobuaki 舟橋 伸昭

舟橋 伸昭 フナハシ ノブアキ

Research Projects

Research Products

Co-Researchers

妊娠期ビタミンD摂取量と児の将来の生活習慣病の発症リスクとの関連性の検討Principal Investigator

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The molecular mechanism of epigenomic regulation by maternal nutritional status in placenta.Principal Investigator

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The investigation of relationship between maternal undernutrition and epigenetic changesPrincipal Investigator

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[Journal Article] PRC2 Components Maintain DNA Hypermethylation of the Upstream Promoter and Regulate Robo4 Expression in Endothelial Cells2020

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[Journal Article] Effects of maternal and fetal choline concentrations on the fetal growth and placental DNA methylation of 12 target genes related to fetal growth, adipogenesis, and energy metabolism2020

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[Journal Article] Genome-wide profiling of histone H3K27 acetylation featured fatty acid signalling in pancreatic beta cells in diet-induced obesity in mice2018

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[Journal Article] A type 2 diabetes-associated SNP in KCNQ1(rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression. Int J Mol Med.2018

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[Journal Article] Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: Comparison with hepatitis virus-related carcinogenesis.2017

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[Journal Article] Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1.2015

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NAID

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[Journal Article] Expression of the Robo4 receptor in endothelial cells is regulated by two AP-1 protein complexes.2015

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[Journal Article] Demethylation of the MafB promoter in a compromised β-cell model.2015

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[Journal Article] YY1 positively regulates human UBIAD1 expression.2015

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[Presentation] 内臓脂肪組織有意に発現する転写因子Gata5による酸化ストレス防御機構2020

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[Presentation] ヒトNASH肝で高発現するAKR1B15の発現制御機序および機能解析2018

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Funahashi Nobuaki 舟橋伸昭

舟橋伸昭フナハシノブアキ

[Journal Article] A type 2 diabetes-associated SNP in KCNQ1(rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a,　potentially affecting CDKN1C expression. Int J Mol Med.2018