Ueno Koji 上野耕司

… Alternative Names

UENO Koji 上野耕司

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Researcher Number	30736070
Other IDs
Affiliation (Current)	2022: 山口大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2016 – 2022: 山口大学, 医学部附属病院, 助教 2015: 山口大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Cardiovascular surgery / Basic Section 55030:Cardiovascular surgery-related Except Principal Investigator Basic Section 55030:Cardiovascular surgery-related / Cardiovascular surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55040:Respiratory surgery-related
Keywords	Principal Investigator microRNA / 細胞外microRNA / エクソソーム / 血管新生 / 虚血プレコンディショニング Except Principal Investigator 細胞シート / 再生医療 / 難治性皮膚潰瘍 / 血管新生 / 細胞移植 … More / エクソソーム / 難治性潰瘍 / 低酸素刺激 / 中型動物モデル / 他家細胞シート / 細胞混合シート移植 / 細胞シート移植治療 / 移植・再生医療 / 血管再生療法 / 脊髄虚血再灌流障害 / 幹細胞エクソソーム / 抗癌剤抵抗性 / RNA修飾 / 非小細胞肺癌 / RNA修飾酵素 / 細胞シート凍結 / 細胞保存 / エクソソーム治療 Less

虚血組織に血管新生を誘導する経静脈投与が可能なエクソソーム血管再生療法の開発
- Principal Investigator
  
  濱野公一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
再生医療における他家積層線維芽細胞シートの新たな緩慢凍結保存法の開発
- Principal Investigator
  
  白澤文吾
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
血管再生療法を可能にする臨床応用可能な大量培養液からのエクソソーム単離法の開発Principal Investigator
- Principal Investigator
  
  上野耕司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
静脈性難治性皮膚潰瘍に対する自家細胞シート移植の成績と患者の細胞増殖能との関係
- Principal Investigator
  
  末廣晃太郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
次世代積層心筋幹細胞シート凍結保存法の開発
- Principal Investigator
  
  桂春作
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
機能増強させた細胞由来のエクソソームを用いたcell-free血管再生療法の開発
- Principal Investigator
  
  濱野公一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
血管新生能を有するmicroRNAを改変した人工核酸による血管新生療法の開発Principal Investigator
- Principal Investigator
  
  上野耕司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
Development of exosomes accumulating in ischemic tissues for angiogenesis
- Principal Investigator
  
  HAMANO Kimikazu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
Development of methods to reduce spinal cord ischemia-reperfusion disorder by exosomes
- Principal Investigator
  
  MORIKAGE Noriyasu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
Elucidation of the role of RNA-modifying enzymes in anticancer drug-resistant non-small cell lung cancer
- Principal Investigator
  
  Tanaka Toshiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Yamaguchi University
Development of cryopreservation method for allogeneic cell sheet
- Principal Investigator
  
  SHIRASAWA Bungo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Yamaguchi University
Development of regenerative therapy for refractory cutaneous ulcers using multi-layered cell sheets
- Principal Investigator
  
  TAKAHASHI Masaya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Yamaguchi University
Development of angiogenesis therapy by microRNA expressed in mice with angiogenic abilityPrincipal Investigator
- Principal Investigator
  
  UENO Koji
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Yamaguchi University
Development of regenerative medicine for refractory skin ulcers using fibroblasts
- Principal Investigator
  
  SUZUKI Ryo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Yamaguchi University
Analysis of extracellular microRNA having protective effects against ischemia-perfusion injury of organs after ischemic preconditioningPrincipal Investigator
- Principal Investigator
  
  UENO Koji
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Yamaguchi University
Development of transplantation therapy using hypoxically preconditioned cell sheets for lower limb ischemic ulcers
- Principal Investigator
  
  HAMANO Kimikazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Yamaguchi University

All 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] Dclk1 Inhibition Cancels 5-FU-induced Cell-cycle Arrest and Decreases Cell Survival in Colorectal Cancer2018
- Author(s)
  Suehiro Y, Takemoto Y, Nishimoto A, Ueno K, Shirasawa B, Tanaka T, Kugimiya N, Suga A, Harada E, Hamano K
- Journal Title
  
  Anticancer Res
  
  Volume: 38 Pages: 6225-6230
- DOI
  10.21873/anticanres.12977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08735
[Journal Article] Autologous fibroblasts, peripheral blood mononuclear cells, and fibrin glue accelerate healing of refractory cutaneous ulcers in diabetic mice2018
- Author(s)
  Mizoguchi T, Ueno K, Yanagihara M, Samura M, Kurazumi H, Suzuki R, Morikage N, Hamano K
- Journal Title
  
  Am J Transl Res
  
  Volume: 10(9) Pages: 2920-2928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10661
[Journal Article] Treatment of Cutaneous Ulcers with Multilayered Mixed Sheets of Autologous Fibroblasts and Peripheral Blood Mononuclear Cells2018
- Author(s)
  Mizoguchi T, Ueno K, Takeuchi Y, Samura M, Suzuki R, Murata T, Hosoyama T, Morikage N, Hamano K
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 47(1) Pages: 201-211
- DOI
  10.1159/000489767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08760, KAKENHI-PROJECT-16K10661
[Journal Article] Autologous fibroblasts, peripheral blood mononuclear cells, and fibrin glue accelerate healing of refractory cutaneous ulcers in diabetic mice2018
- Author(s)
  Mizoguchi T, Ueno K, Yanagihara M, Samura M, Kurazumi H, Suzuki R, Morikage N, Hamano K
- Journal Title
  
  Am J Transl Res
  
  Volume: 10(9) Pages: 2920-2928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08760
[Journal Article] Ulcer healing effect of autologous mixed sheets consisting of fibroblasts and peripheral blood mononuclear cells in rabbit ischemic hind limb.2017
- Author(s)
  Takeuchi Y, Ueno K, Mizoguchi T, Samura M, Harada T, Oga A, Murata T, Hosoyama T, Morikage N, Hamano K
- Journal Title
  
  Am J Transl Res
  
  Volume: 15 Pages: 2340-2351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04939
[Journal Article] Increased plasma VEGF levels following ischemic preconditioning are associated with downregulation of miRNA-762 and miR-3072-5p2016
- Author(s)
  Ueno K, Takeuchi Y, Samura M, Tanaka Y, Nakamura T, Nishimoto A, Murata T, Hosoyama T, Hamano K
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 28538-28538
- DOI
  10.1038/srep36758
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04939, KAKENHI-PROJECT-26462110, KAKENHI-PROJECT-15K19921
[Patent] 末梢血単核球又は末梢血単核球より分泌される因子を伴う線維芽細胞を含む細胞シート2015
- Inventor(s)
  濱野公一、上野耕司、細山　徹
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-10-28
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] 難治性皮膚潰瘍に対する線維芽細胞シートのCollagen IIIを活性化させる因子の基礎的検討2017
- Author(s)
  上野耕司、竹内由利子、溝口高弘、佐村誠、細山徹、濱野公一
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  宮城県仙台市　仙台国際センター
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] 難治性皮膚潰瘍に対する積層化細胞シートの基礎的検討2017
- Author(s)
  溝口高弘、上野耕司、竹内由利子、佐村誠、西本新、細山徹、森景則保、美甘章仁、濱野公一
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  宮城県仙台市　仙台国際センター
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] 末梢血単核球と線維芽細胞からなる細胞混合シートを用いた難治性皮膚潰瘍治療の臨床応用に向けて2017
- Author(s)
  竹内由利子、上野耕司、溝口高弘、西本新、細山徹、森景則保、濱野公一
- Organizer
  第47回日本心臓血管外科学会総会
- Place of Presentation
  東京　グランドニッコウー東京台場
- Year and Date
  2017-02-27
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] マウス難治性皮膚潰瘍モデルにおける細胞混合シートの効果2017
- Author(s)
  竹内由利子、上野耕司、溝口髙弘、細山徹、濱野公一
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  宮城県仙台市　仙台国際センター
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] アロ細胞混合シートを用いた難治性皮膚潰瘍治療の検討と移植された細胞シートの残存有無の検証2016
- Author(s)
  上野耕司、竹内由利子、佐村　誠、田中裕也、中村玉美、西本　新、細山　徹、濱野公一
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪府大阪市　大阪国際会議場
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] 虚血プレコンディショニング後のVEGFの増加はmiRNA-762とmiR-3072-5pの発現低下と関連する2016
- Author(s)
  上野耕司、佐村誠、中村玉美、田中裕也、竹内由利子、河村大智、髙橋雅弥、細山徹、森景則保、濱野公一
- Organizer
  第8会日本RNAi研究会/第3回日本細胞外小胞学会
- Place of Presentation
  グランドプリンスホテル広島（広島県広島市）
- Year and Date
  2016-08-31
- Data Source
  KAKENHI-PROJECT-15K19921
[Presentation] 磁石埋込全層欠損による難治性皮膚潰瘍モデルの開発2016
- Author(s)
  竹内由利子、田中裕也、中村玉美、佐村　誠、上野耕司、西本　新、細山　徹、濱野公一
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪府大阪市　大阪国際会議場
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] 末梢血単核球と線維芽細胞の細胞混合シートを用いた難治性皮膚潰瘍治療の基礎的検討2016
- Author(s)
  竹内由利子、上野耕司、田中裕也、中村玉美、佐村　誠、西本　新、細山　徹、森景則保、美甘章仁、濱野公一
- Organizer
  第46回日本心臓血管外科学会学術総会
- Place of Presentation
  愛知県名古屋市　名古屋国際会議場
- Year and Date
  2016-02-15
- Data Source
  KAKENHI-PROJECT-15H04939
[Presentation] 虚血プレコンディショニングによる細胞外microRNAの解析2015
- Author(s)
  上野耕司
- Organizer
  第7回日本RNAi研究会
- Place of Presentation
  グランドプリンスホテル広島（広島県広島市）
- Year and Date
  2015-08-26
- Data Source
  KAKENHI-PROJECT-15K19921

1. HAMANO Kimikazu (60263787)

# of Collaborated Projects: 10 results

# of Collaborated Products: 13 results
2. 溝口高弘 (90844796)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. MORIKAGE Noriyasu (50335741)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. SUZUKI Ryo (10570319)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. 佐村誠 (30773402)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. SHIRASAWA Bungo (80444719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. TAKAHASHI Masaya (60634730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. Tanaka Toshiki (50457305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 細山徹 (20638803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
10. 李桃生 (50379997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 上田和弘 (90420520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 桂春作 (40457304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 末廣晃太郎 (10569312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藏澄宏之 (50645116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 石井治之 (80565820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ueno Koji 上野 耕司

UENO Koji 上野 耕司

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血管再生療法を可能にする臨床応用可能な大量培養液からのエクソソーム単離法の開発Principal Investigator

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血管新生能を有するmicroRNAを改変した人工核酸による血管新生療法の開発Principal Investigator

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Development of angiogenesis therapy by microRNA expressed in mice with angiogenic abilityPrincipal Investigator

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Analysis of extracellular microRNA having protective effects against ischemia-perfusion injury of organs after ischemic preconditioningPrincipal Investigator

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Ueno Koji 上野耕司

UENO Koji 上野耕司