Mashimo Masato 間下雅士

Researcher Number	30738886
Affiliation *help	2015 – 2018 : 同志社女子大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 48030:Pharmacology-related Except Principal Investigator Pharmacology in pharmacy
Keywords	Principal Investigator DNA damage / ADP-リボシル化 / cell death / apoptosis / PARP1 / caspase / 細胞膜修復 / Parthanatos / parthanatos / ADP-ribose … More Except Principal Investigator … More

細胞膜修復に関わるADP-リボシル化修飾酵素の探索およびその細胞内機序の解明Principal InvestigatorOngoing
- Principal Investigator
  
  間下雅士
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Doshisha Women's College of Liberal Arts
内因性nAChR活性化蛋白質SLURP-1のT細胞分化に及ぼす作用の薬学的研究Ongoing
- Principal Investigator
  
  川島紘一郎
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kitasato University
ムスカリン受容体を介するリンパ球コリン作動系のT細胞分化における生理的役割の解明Ongoing
- Principal Investigator
  
  藤井健志
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Regulatory mechanism of intracellular localization of PAR in neuronal cell deathPrincipal Investigator
- Principal Investigator
  
  Mashimo Masato
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts

All 2017 2016 2015

All Journal Article Presentation

[Journal Article] Acetylcholine released from T cells regulates intracellular Ca2+, IL-2 secretion and T cell proliferation through nicotinic acetylcholine receptor2017
- Author(s)
  Mashimo M, Iwasaki Y, Inoue S, Saito S, Kawashima K, Fujii T.
- Journal Title
  
  Life Sciences
  
  Volume : 172 Pages : 13-18
- DOI
  10.1016/j.lfs.2016.12.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18871, KAKENHI-PROJECT-15K07979
[Journal Article] Physiological functions of the cholinergic system in immune cells2017
- Author(s)
  Takeshi Fujii、Masato Mashimo、Yasuhiro Moriwaki、Hidemi Misaswa、Shiro Ono、Kazuhide Horiguchi、Koichiro Kawashima
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume : 印刷中
- DOI
  10.1016/j.jphs.2017.05.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07979
[Journal Article] Functional Role of ADP-Ribosyl-Acceptor Hydrolase 3 in poly(ADP-Ribose) Polymerase-1 Response to Oxidative Stress.2016
- Author(s)
  Mashimo M, Moss J.
- Journal Title
  
  Curr Protein Pept Sci.
  
  Volume : 17 Pages : 633-640
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18871
[Journal Article] CRAC channels are required for [Ca2+]i oscillations and c-fos gene expression after muscarinic acetylcholine receptor activation in leukemic T cells2016
- Author(s)
  Mashimo M, Yurie Y, Kawashima K, Fujii T.
- Journal Title
  
  Life Sciences
  
  Volume : 161 Pages : 45-50
- DOI
  10.1016/j.lfs.2016.07.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18871, KAKENHI-PROJECT-15K07979
[Journal Article] Functional Role of ADP-Ribosyl-Acceptor Hydrolase 3 in poly(ADPRibose) Polymerase-1 Response to Oxidative Stress2016
- Author(s)
  Mashimo Masato, Joel Moss
- Journal Title
  
  Current Protein and Peptide Science
  
  Volume : in press
- DOI
  10.2174/1389203717666160419144603
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18871
[Presentation] PARP1 の細胞質への局在変化は、 PARP1 依存的な細胞死 parthanatos を惹起する2016
- Author(s)
  大西真由、宇野愛莉奈、藤井健志、間下雅士
- Organizer
  第 66 回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪薬科大学
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-15K18871
[Presentation] PARP1 の断片化は PAR の細胞質への移行を促進し , parthanatos を引き起こす2016
- Author(s)
  谷道あかり、大西真由、宇野愛莉奈、藤井健志、間下雅士
- Organizer
  第 130 回日本薬理学会近畿部会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15K18871
[Presentation] Role for α7 nicotinic acetylcholine receptors in naïve T cell differentiation into regulatory T cell2016
- Author(s)
  Koichiro Kawashima、Masato Mashimo、Takeshi Fujii、Yasuhiro Moriwaki、Hidemi Misawa、 Shiro Ono
- Organizer
  Neuroscience 2016
- Place of Presentation
  サンディエゴコンベンションセンター（米国、カリフォルニア州）
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07979
[Presentation] 制御性 T 細胞分化におけるα 7 ニコチン性アセチルコリン受容体の役割2016
- Author(s)
  井上笙子、斉藤聖子、間下雅士、竹島詩織、奥山洋美、小野史郎、川島紘一郎、藤井健志
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館，広島市
- Data Source
  KAKENHI-PROJECT-15K07969
[Presentation] Role for α7 nicotinic acetylcholine receptors in naive T cell differentiation into regulatory T cells.2016
- Author(s)
  Kawashima K, Mashimo M, Fujii T, Moriwaki M, Misawa H, Ono S
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-15K07969
[Presentation] α7 ニコチン受容体シグナルは抗原提示細胞機能の抑制を介してヘルパー T 細胞の分化誘導を阻害する2016
- Author(s)
  井上笙子、斉藤聖子、間下雅士、竹島詩織、奥山洋美、小野史郎、川島紘一郎、藤井健志
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館，広島市
- Data Source
  KAKENHI-PROJECT-15K07969
[Presentation] T リンパ球における海馬由来コリン作動性神経刺激ペプチドの作用2016
- Author(s)
  齋藤有華、間下雅士、川島紘一郎、藤井健志
- Organizer
  第 66 回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪薬科大学（大阪府、高槻市）
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-15K07979
[Presentation] α7 ニコチン受容体シグナルは抗原提示細胞の抗原プロセシング過程を阻害して制御性T 細胞分化を抑制する2016
- Author(s)
  小森眞紗代、間下雅士、松井悠理子、井上笙子、斎藤聖子、小野史郎、川島紘一郎、奥山洋美、藤井健志
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都大学（京都府、京都市）
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15K07979
[Presentation] Tリンパ球モデル細胞MOLT3におけるアセチルコリンのオートクラインおよびパラクライン作用による細胞増殖およびIL-2の産生への影響。2015
- Author(s)
  岩崎有可里、間下雅士、井上笙子、斎藤聖子、川島紘一郎、藤井健志
- Organizer
  第65回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪大谷大学，富田林市，大阪府
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K07969
[Presentation] ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress2015
- Author(s)
  間下雅士、加藤治郎、Joel Moss
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場 (岐阜県、岐阜市)
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K18871
[Presentation] 細胞死を惹起する poly(ADP-ribose) の核外への移行の時空間的解析2015
- Author(s)
  大西真由、宇野愛莉奈、藤井健志、間下雅士
- Organizer
  第 65 回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪大谷大学 (大阪府、富田林市)
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K18871
[Presentation] ADP-ribosyl-acceptor hydrolase 3 は、酸化ストレスによるpoly(ADP-ribose) polymerase 1依存的な細胞死 parthanatos を抑制する2015
- Author(s)
  間下雅士、加藤治郎、Joel Moss
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド (兵庫県、神戸市)
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K18871
[Presentation] Tリンパ球モデル細胞MOLT-3細胞におけるアセチルコリンのオートクラインおよびパラクライン作用による細胞増殖およびIL-2の産生への影響2015
- Author(s)
  岩崎　有可里、間下　雅士、井上　笙子、斎藤　聖子、川島　紘一郎、藤井　健志
- Organizer
  第65回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪大谷大学（大阪府、富田林市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K07979

1. 藤井健志 (80255380)

# of Collaborated Projects : 2results

# of Collaborated Products : 11results
2. 川島紘一郎 (70095008)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
3. 堀口和秀 (20377451)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

Mashimo Masato 間下 雅士

Research Projects

Research Products

Co-Researchers

細胞膜修復に関わるADP-リボシル化修飾酵素の探索およびその細胞内機序の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

内因性nAChR活性化蛋白質SLURP-1のT細胞分化に及ぼす作用の薬学的研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ムスカリン受容体を介するリンパ球コリン作動系のT細胞分化における生理的役割の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory mechanism of intracellular localization of PAR in neuronal cell deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acetylcholine released from T cells regulates intracellular Ca2+, IL-2 secretion and T cell proliferation through nicotinic acetylcholine receptor2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physiological functions of the cholinergic system in immune cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional Role of ADP-Ribosyl-Acceptor Hydrolase 3 in poly(ADP-Ribose) Polymerase-1 Response to Oxidative Stress.2016

Author(s)

Journal Title

Data Source

[Journal Article] CRAC channels are required for [Ca2+]i oscillations and c-fos gene expression after muscarinic acetylcholine receptor activation in leukemic T cells2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional Role of ADP-Ribosyl-Acceptor Hydrolase 3 in poly(ADPRibose) Polymerase-1 Response to Oxidative Stress2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] PARP1 の細胞質への局在変化は、 PARP1 依存的な細胞死 parthanatos を惹起する2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PARP1 の断片化は PAR の細胞質への移行を促進し , parthanatos を引き起こ す2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Role for α7 nicotinic acetylcholine receptors in na&iuml;ve T cell differentiation into regulatory T cell2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 制御性 T 細胞分化におけるα 7 ニコチン性アセチルコリン受容体の役割2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Role for α7 nicotinic acetylcholine receptors in naive T cell differentiation into regulatory T cells.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Mashimo Masato 間下雅士

[Presentation] PARP1 の断片化は PAR の細胞質への移行を促進し , parthanatos を引き起こす2016

[Presentation] Role for α7 nicotinic acetylcholine receptors in naïve T cell differentiation into regulatory T cell2016

[Presentation] α7 ニコチン受容体シグナルは抗原提示細胞機能の抑制を介してヘルパー T 細胞の分化誘導を阻害する2016

[Presentation] α7 ニコチン受容体シグナルは抗原提示細胞の抗原プロセシング過程を阻害して制御性T 細胞分化を抑制する2016