OTAKA AKIHISA 大高晋之

… Alternative Names

大高晋之オオタカアキヒサ

Otaka Akihisa 大高晋之

Less

Researcher Number	30739561
Other IDs
Affiliation (Current)	2022: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員
Affiliation (based on the past Project Information) *help	2020: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2019 – 2020: 関西大学, 先端科学技術推進機構, 特別任命助教 2019: 関西大学, 先端科学技術推進機構, 特別任用助教 2015 – 2017: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員 2015: 国立研究開発法人国立循環器病研究センター, 研究所, 流動
Review Section/Research Field	Principal Investigator Biofunction/Bioprocess / Biomedical engineering/Biomaterial science and engineering / Basic Section 90120:Biomaterials-related Except Principal Investigator General surgery / Basic Section 90120:Biomaterials-related
Keywords	Principal Investigator 細胞ローリング / ラベルフリー細胞分離 / iPS細胞 / 心筋分化 / 高分子界面 / マイクロ流路 / MPC / 糖代謝 / シアル酸 / チオール-エン反応 … More / ゲル / 糖鎖改変 / コラーゲン / ポリエチレングリコール / 再生医療 / 3Dプリンター / 糖鎖 / 細胞 / 表面修飾 / クリック反応 … More Except Principal Investigator 人工臓器学 / バイオテクノロジー / 循環器・高血圧 / 骨治療 / ポリリン酸エステル / プロドラッグ / 骨粗鬆症 / 骨転移 Less

Investigation of optimal polyphosphoester structure for bone treatment
- Principal Investigator
  
  岩崎泰彦
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kansai University
糖鎖改変細胞を用いた光造形による組織構築Principal Investigator
- Principal Investigator
  
  大高晋之
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  National Cardiovascular Center Research Institute
  Kansai University
Evaluation of the effect of cell enrichment process on iPS cell differentiationPrincipal Investigator
- Principal Investigator
  
  Otaka Akihisa
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biofunction/Bioprocess
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Cardiovascular Center Research Institute
Development of a new DCM therapeutic strategy, DNCS, to remove etiologic factors in the blood
- Principal Investigator
  
  Minatoya Kenji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
  National Cardiovascular Center Research Institute

All 2020 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] Endocytosis of poly(ethylene sodium phosphate) by macrophages and the effect of polymer length on cellular uptake2019
- Author(s)
  Akihisa Otaka, Yasuhiko Iwasaki
- Journal Title
  
  Journal of Industrial and Engineering Chemistry
  
  Volume: 75 Pages: 115-122
- DOI
  10.1016/j.jiec.2019.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03185, KAKENHI-PROJECT-19H04474
[Journal Article] 抗SSEA1抗体固定化流路界面の細胞挙動を用いた未分化細胞分離2017
- Author(s)
  大高晋之
- Journal Title
  
  バイオマテリアル学会<生体材料>
  
  Volume: 35 Pages: 28-29
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21696
[Journal Article] Label-free separation of induced pluripotent stem cells with anti-SSEA-1 antibody immobilized microfluidic channel2017
- Author(s)
  A. Otaka, K. Kitagawa, T. Nakaoki, M. Hirata, K. Fukazawa, K. Ishihara, A. Mahara, T. Yamaoka
- Journal Title
  
  Langmuir
  
  Volume: 33 Pages: 1576-1582
- DOI
  10.1021/acs.langmuir.6b04070
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21696, KAKENHI-PROJECT-16H03186
[Presentation] ポリリン酸エステルを用いた二相性骨粗鬆症治療薬の開発2020
- Author(s)
  大高晋之，高橋功次，清野謙二郎，岩﨑泰彦
- Organizer
  第69回高分子討論会
- Data Source
  KAKENHI-PROJECT-19K20701
[Presentation] Bone targeting phospholipid polymers to solubilize lipophilic anticancer drugs2020
- Author(s)
  Akihisa OTAKA, Tomoki YAMAGUCHI, Ryoya SAISHO, Toru HIRAGA, Yasuhiko IWASAKI
- Organizer
  11th WORLD BIOMATERIALS CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20701
[Presentation] 光を用いて糖鎖改変細胞を立体積層する技術の開発2020
- Author(s)
  大高晋之, 廣田泰佑, 岩﨑泰彦
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K20701
[Presentation] 骨転移治療を目指したビスホスホネート導入双性イオン型ポリマー2019
- Author(s)
  大高晋之，山口知己，税所凌弥，平賀徹，岩﨑泰彦
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-19H04474
[Presentation] The interaction of polyphosphoesters and bone cells2019
- Author(s)
  Otaka A., Imai Y., Inonue N., Nakamura M, Iwasaki Y
- Organizer
  第68回高分子年次大会
- Data Source
  KAKENHI-PROJECT-19H04474
[Presentation] リン酸エステルポリマーの骨系細胞への影響2019
- Author(s)
  大高晋之，今井雄太，井上直之，中村美穂，岩﨑泰彦
- Organizer
  第48回医用高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04474
[Presentation] Polyphosphoesters for modulation of bone cell behaviors2019
- Author(s)
  Iwasaki Y, Otaka A
- Organizer
  FAPS2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04474
[Presentation] 骨転移がん治療を目指した薬物輸送システムの構築2019
- Author(s)
  大高晋之，山口知己，平賀徹，岩﨑泰彦
- Organizer
  第30回バイオフロンティア講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19H04474
[Presentation] 転移性腫瘍を標的とする高分子薬物担体の創出2019
- Author(s)
  税所凌弥，大高晋之，平賀徹，岩﨑泰彦
- Organizer
  第48回医用高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04474
[Presentation] 機能性両親媒性ポリマーによる骨転移性腫瘍の標的化2019
- Author(s)
  税所凌弥，大高晋之，平賀徹，岩﨑泰彦
- Organizer
  第65回高分子研究発表会(神戸)
- Data Source
  KAKENHI-PROJECT-19H04474
[Presentation] 抗SSEA-１抗体を固定化したマイクロ流路による未分化iPS細胞の分離2016
- Author(s)
  大高晋之, 北川和宜, 平田みつひ, 深澤今日子, 中沖隆彦, 石原一彦, 馬原淳, 山岡哲二
- Organizer
  日本機械学会第28回バイオエンジニアリング講演会
- Place of Presentation
  東京工業大学(東京都)
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] Evaluation of iPS cell rolling phenotype on anti-SSEA-1 antibody immobilized microfluidic channel as a pluripotency marker2016
- Author(s)
  A. Otaka, A. Mahara, T. Yamaoka
- Organizer
  20th Anniversary International Symposium of the Korean Society for Biomaterials 2016
- Place of Presentation
  韓国・ソウル・Korea Institute of Science and Technology
- Year and Date
  2016-09-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] 細胞ローリングカラムを用いた未分化iPS細胞の分離2016
- Author(s)
  大高晋之, 北川和宜, 平田みつひ, 深澤今日子, 中沖隆彦, 石原一彦, 馬原淳, 山岡哲二
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] 抗体固定化マイクロ流路を用いたSSEA-1発現量による未分化iPS細胞のラベルフリー分離2016
- Author(s)
  大高晋之,平田みつひ, 馬原淳, 山岡哲二
- Organizer
  第45回医用高分子シンポジウム
- Place of Presentation
  東京・産業技術総合研究所臨海副都心センター
- Year and Date
  2016-07-25
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] 抗体固定化細胞ローリングカラムによるiPS細胞由来心筋前駆細胞のラベルフリー単離の試み2016
- Author(s)
  北川和宜, 大高晋之, 平田みつひ, 中沖隆彦, 馬原淳, 山岡哲二
- Organizer
  第62回高分子研究発表会（神戸）
- Place of Presentation
  兵庫・兵庫県民会館
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] Isolation of undifferentiated iPS cell based on cell rolling phenotype in antibody immobilized microfluidic channel2016
- Author(s)
  A. Otaka, A. Mahara, T. Yamaoka
- Organizer
  the 6th Stanford Bio-X & ADATE Symposium
- Place of Presentation
  アメリカ・カリフォルニア・Stanford University
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] Label free undifferentiated iPS cell separation using anti SSEA-1 antibody coated microfluidic channels2016
- Author(s)
  Akihisa Otaka, Kazuki Kitagawa, Mitsuhi Hirata, Kyoko Fukazawa, Takahiko Nakaoki, Kazuhiko Ishihara, Atsushi Mahara and Tetsuji Yamaoka
- Organizer
  CiRA / ISSCR International Symposium 2016
- Place of Presentation
  京都大学（京都府）
- Year and Date
  2016-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] Evaluation of iPS cell rolling phenotype on anti-SSEA-1 antibody immobilized microfluidic channel as a pluripotency marker2016
- Author(s)
  A. Otaka, A. Mahara, T. Yamaoka
- Organizer
  日本バイオマテリアル学会シンポジウム2016
- Place of Presentation
  福岡・福岡国際会議場
- Year and Date
  2016-11-21
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] 抗Flk1抗体固定化細胞ローリングカラム内のiPS細胞由来心筋前駆細胞の移動速度評価2016
- Author(s)
  北川和宜, 大高晋之, 平田みつひ, 深澤今日子, 中沖隆彦, 石原一彦, 馬原淳, 山岡哲二
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  兵庫・神戸国際会議場
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-15K21696
[Presentation] The effect of immobilized antibody density on iPS cell rolling behavior in cell rolling column2015
- Author(s)
  A. Otaka, K. Kitagawa, A. Mahara, K. Ishihara, T. Nakaoki, T. Yamaoka
- Organizer
  4th TERMIS World Congress
- Place of Presentation
  Boston,MA
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21696

1. Minatoya Kenji (20393241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 山岡哲二 (50243126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. キアラムニッソマリア (50616084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 馬原淳 (80416221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 徐ユイ (10757678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 岩崎泰彦 (90280990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

OTAKA AKIHISA 大高 晋之

大高 晋之 オオタカ アキヒサ

Otaka Akihisa 大高 晋之

Research Projects

Research Products

Co-Researchers

Investigation of optimal polyphosphoester structure for bone treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖鎖改変細胞を用いた光造形による組織構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of the effect of cell enrichment process on iPS cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new DCM therapeutic strategy, DNCS, to remove etiologic factors in the blood

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Endocytosis of poly(ethylene sodium phosphate) by macrophages and the effect of polymer length on cellular uptake2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 抗SSEA1抗体固定化流路界面の細胞挙動を用いた未分化細胞分離2017

Author(s)

Journal Title

Data Source

[Journal Article] Label-free separation of induced pluripotent stem cells with anti-SSEA-1 antibody immobilized microfluidic channel2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] ポリリン酸エステルを用いた二相性骨粗鬆症治療薬の開発2020

Author(s)

Organizer

Data Source

[Presentation] Bone targeting phospholipid polymers to solubilize lipophilic anticancer drugs2020

Author(s)

Organizer

Data Source

[Presentation] 光を用いて糖鎖改変細胞を立体積層する技術の開発2020

Author(s)

Organizer

Data Source

[Presentation] 骨転移治療を目指したビスホスホネート導入双性イオン型ポリマー2019

Author(s)

Organizer

Data Source

[Presentation] The interaction of polyphosphoesters and bone cells2019

Author(s)

Organizer

Data Source

[Presentation] リン酸エステルポリマーの骨系細胞への影響2019

Author(s)

Organizer

Data Source

[Presentation] Polyphosphoesters for modulation of bone cell behaviors2019

Author(s)

Organizer

Data Source

[Presentation] 骨転移がん治療を目指した薬物輸送システムの構築2019

Author(s)

Organizer

Data Source

[Presentation] 転移性腫瘍を標的とする高分子薬物担体の創出2019

Author(s)

Organizer

Data Source

OTAKA AKIHISA 大高晋之

大高晋之オオタカアキヒサ

Otaka Akihisa 大高晋之