INOUE Yui 井上維

Researcher Number	30750442
Affiliation (based on the past Project Information) *help	2016 – 2019: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), がん薬物療法研究部, 共同研究員
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Dermatology
Keywords	Principal Investigator Kras / プロテインホスファターゼ / メラノサイト / ケラチノサイト / 触媒サブユニット / PP6 / 皮膚腫瘍 / メラノーマ / Braf / 皮膚腫瘍学

Ppp6c functions as a tumor suppressor in skin carcinogenesis.Principal Investigator
- Principal Investigator
  
  Inoue Yui
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Ppp6c deletion promotes mutated RAS-initiated tumor formation in keratinocytes.Principal Investigator
- Principal Investigator
  
  INOUE Yui
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center

All 2018 2017 2016

All Journal Article Presentation

[Journal Article] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-ras G12D -driven tumor promotion2018
- Author(s)
  Kurosawa Koreyuki、Inoue Yui、Kakugawa Yoichiro、Yamashita Yoji、Kanazawa Kosuke、Kishimoto Kazuhiro、Nomura Miyuki、Momoi Yuki、Sato Ikuro、Chiba Natsuko、Suzuki Mai、Ogoh Honami、Yamada Hidekazu、Miura Koh、Watanabe Toshio、Tanuma Nobuhiro、Tachi Masahiro、Shima Hiroshi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 7 Pages: 2178-2187
- DOI
  10.1111/cas.13638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K10660, KAKENHI-PROJECT-18K16043, KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K16358, KAKENHI-PROJECT-17K16876, KAKENHI-PROJECT-18K09243, KAKENHI-PROJECT-16K07187, KAKENHI-PROJECT-17K19620
[Journal Article] PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.2018
- Author(s)
  M Morita, T Sato, M Nomura, Y Sakamoto, Y Inoue, R Tanaka, S Ito, K Kurosawa, K Yamaguchi, Y Sugiura, H Takizaki, Y Yamashita, R Katakura, I Sato, Y Okada, H Watanabe, G Kondoh, et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 12 Issue: 3 Pages: 355-367
- DOI
  10.1016/j.ccell.2018.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K09597, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K16876, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19745, KAKENHI-PROJECT-17K07187, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K19606, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-16K07187, KAKENHI-PROJECT-17K07231
[Journal Article] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-rasG12D-driven tumor promotion.2018
- Author(s)
  Kurosawa K, Inoue Y, Kakugawa Y, Yamashita Y, Kanazawa K, Kishimoto K, Nomura M, Momoi Y, Sato I, Chiba N, Suzuki M, Ogoh H, Yamada H, Miura K, Watanabe T, Tanuma N, Tachi M, and Shima H
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19745
[Journal Article] Ex vivo model of non-small cell lung cancer using mouse lung epithelial cells.2017
- Author(s)
  Sato T, Morita M, Tanaka R, Inoue Y, Nomura M, Sakamoto Y, Miura K, Ito S, Sato I, Tanaka N, Abe J, Takahashi S, Kawai M, Sato M, Hippo Y, Shima H, Okada Y, Tanuma N
- Journal Title
  
  Oncol Lett.
  
  Volume: 14(6) Pages: 6863-6868
- DOI
  10.3892/ol.2017.7098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K10660, KAKENHI-PROJECT-17K10796, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-17K16876, KAKENHI-PROJECT-16K19745
[Presentation] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-rasG12D-driven tumor promotion.2018
- Author(s)
  Kosuke Kanazawa, Kazuhiro Kishimoto, Yui Inoue, Koh Miura, Nobuhiro Tanuma, and Hiroshi Shima
- Organizer
  Mechanisms & Models of Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16043
[Presentation] プロテインホスファターゼPP6の機能不全は、ケラチノサイトにおいて、変異型K-rasで誘導される腫瘍化を著しく亢進させる2018
- Author(s)
  岸本和大、金澤孝祐、井上維、田沼延公、島礼
- Organizer
  生化学会東北支部会
- Data Source
  KAKENHI-PROJECT-18K16043
[Presentation] Pyruvate kinase Mの両isoformを欠損するマウスの解析2016
- Author(s)
  田中遼太、小河穂波、井上維、山下洋二、三浦康、河合賢郎、佐藤郁郎、渡邊利雄、島礼、田沼延公
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  宮城県・仙台市
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K19745
[Presentation] Functional analysis of the pyruvate kinase M(Pkm) isoforms by transformation experiments of mouse lungs epithelia cells2016
- Author(s)
  佐藤卓、坂本良美、野村美有樹、井上維、盛田麻美、田中遼太、渡邊利雄、佐藤郁郎、島礼、岡田克典、田沼延公
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19745
[Presentation] 遺伝子改変肺上皮細胞を用いた形質転換実験による、代謝酵素Pkmの機能解析2016
- Author(s)
  佐藤卓、坂本良美、野村美有樹、井上維、盛田麻美、田中遼太、渡邊利雄、佐藤郁郎、島礼、岡田克典、田沼延公
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  宮城県・仙台市
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K19745
[Presentation] 発がんプロモーターオカダ酸の標的、PP6の皮膚がん抑制遺伝子としての意義2016
- Author(s)
  島礼、黒沢是之、小河穂波、桃井勇貴、井上維、田沼延公、渡邊利雄
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  宮城県・仙台市
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K19745

1. KAWAI Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 佐藤郁郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 島礼

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 渡辺利雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INOUE Yui 井上 維

Research Projects

Research Products

Co-Researchers

Ppp6c functions as a tumor suppressor in skin carcinogenesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ppp6c deletion promotes mutated RAS-initiated tumor formation in keratinocytes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-ras G12D -driven tumor promotion2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-rasG12D-driven tumor promotion.2018

Author(s)

Journal Title

Data Source

[Journal Article] Ex vivo model of non-small cell lung cancer using mouse lung epithelial cells.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-rasG12D-driven tumor promotion.2018

Author(s)

Organizer

Data Source

[Presentation] プロテインホスファターゼPP6の機能不全は、ケラチノサイトにおいて、変異型K-rasで誘導される腫瘍化を著しく亢進させる2018

Author(s)

Organizer

Data Source

[Presentation] Pyruvate kinase Mの両isoformを欠損するマウスの解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Functional analysis of the pyruvate kinase M(Pkm) isoforms by transformation experiments of mouse lungs epithelia cells2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 遺伝子改変肺上皮細胞を用いた形質転換実験による、代謝酵素Pkmの機能解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 発がんプロモーターオカダ酸の標的、PP6の皮膚がん抑制遺伝子としての意義2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

INOUE Yui 井上維