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Uekusa Yoshinori  植草 義徳

Researcher Number 30753024
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-1654-5403
Affiliation (Current) 2022: 慶應義塾大学, 薬学部(芝共立), 助教
2022: 国立医薬品食品衛生研究所, 食品部, 協力研究員
Affiliation (based on the past Project Information) *help 2018 – 2021: 慶應義塾大学, 薬学部(芝共立), 助教
Review Section/Research Field
Principal Investigator
Basic Section 47050:Environmental and natural pharmaceutical resources-related
Except Principal Investigator
Basic Section 38050:Food sciences-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Medium-sized Section 37:Biomolecular chemistry and related fields
Keywords
Principal Investigator
フラボノイド類 / フラボン類 / フラボノール類 / リン脂質膜親和性 / NMR / 分子間相互作用 / リン脂質膜 / 構造活性相関 / フラボノイド / フラボン … More / フラボノール / IAM / 相互作用 / 細胞透過性 / 生物活性 / 生物活性強度 / 核磁気共鳴 … More
Except Principal Investigator
紅茶 / 紅茶ポリフェノール / テアフラビン類 / リン脂質膜 / NMR / 原子間力顕微鏡 / リポソーム / ポリフェノール / AFM / NOE / カカオポリフェノール / 柿ポリフェノール / 脂質膜 / リン脂質 / 分子間相互作用 / 胆汁酸ミセル / 脂質膜二重層 / テアフラビン / リン脂質二重層 / フラボノイド / 抗炎症作用 / 一酸化窒素(NO)産生抑制 / プロスタグランジン(PG)産生抑制 / オウゴン / NO産生抑制 / PG産生 / ポリメトキシフラボン / リン脂質膜親和性 / 混合物 / 一酸化窒素 / PGE2 / シアノバクテリア / 天然有機化合物 / ペプチド / 単離・構造決定 / 全合成 Less
  • Research Projects

    (4 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (7 People)
  •  Development of a platform for drug discovery by isolation and synthesis of novel natural products derived from unculturable marine cyanobacteria

    • Principal Investigator
      吉田 将人
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 37:Biomolecular chemistry and related fields
    • Research Institution
      University of Tsukuba
  •  Analysis of the interaction between flavones and phospholipid membranes in the early stage of biological activity expressionPrincipal Investigator

    • Principal Investigator
      Uekusa Yoshinori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Keio University
  •  Molecular interaction of theaflavins with phospholipids

    • Principal Investigator
      NAKAYAMA Tsutomu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Tokyo University of Agriculture
  •  Mechanistic study of anti-inflammatory activity of flavonoid mixtures and its application

    • Principal Investigator
      Kiuchi Fumiyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Keio University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Oxidation of methylophiopogonanone A on the surface of TLC plate2022

    • Author(s)
      Kiuchi, F., Uekusa, Y., Narukawa, Y.
    • Journal Title

      Journal of Natural Medicines

      Volume: 76 Pages: 504-508

    • DOI

      10.1007/s11418-022-01604-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Journal Article] Anti-trypanosome screening of Salvadoran flora2022

    • Author(s)
      Castillo, U. G., Komatsu, A., Martinez, M. L., Menjivar, J., Nunez, M. J., Uekusa, Y., Narukawa, Y., Kiuchi, F., Nakajima-Shimada, J.
    • Journal Title

      Journal of Natural Medicines

      Volume: 76 Pages: 259-267

    • DOI

      10.1007/s11418-021-01562-6

    • NAID

      40022799597

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Journal Article] Synthesis of Methylophiopogonanone A2020

    • Author(s)
      Katagiri R, Uekusa Y, Narukawa Y, Kiuchi F
    • Journal Title

      Heterocycles

      Volume: 100 Pages: 803-808

    • DOI

      10.3987/com-20-14231

    • NAID

      40022257929

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06721, KAKENHI-PROJECT-18K06734
  • [Presentation] Baicalinとberberine類縁体の間で生じる化合物間相互作用の解析2022

    • Author(s)
      谷岡ちはる,植草義徳,遠周直人,木内文之,菊地晴久
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] 分子ネットワーク解析を活用した海洋性シアノバクテリア由来新規化合物の効率的探索2022

    • Author(s)
      小川慧人,植草義徳,木内文之,William H. Gerwick,菊地晴久
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] 分子ネットワークを用いたシアノバクテリア由来の新規化合物の単離2021

    • Author(s)
      小川慧人,植草義徳,木内文之,William H. Gerwick,菊地晴久
    • Organizer
      第65回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] 栄養源バクテリアの変化による細胞性粘菌由来新規二次代謝産物の探索2021

    • Author(s)
      室谷拓冶,佐々木瞳,江口裕美,植草義徳,菊地晴久
    • Organizer
      日本細胞性粘菌学会第11回例会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] Development of peptide alkaloid-type compound library based on brefeldin A by molecular skeleton recombination strategy2021

    • Author(s)
      Sato, Y., Nishimura, T., Shiga, K., Sugawara, A., Uekusa, Y., Kikuchi, H.
    • Organizer
      13th AFMC International Medicinal Chemistry Symposium (AIMECS 2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] NMRを用いたテアフラビン類によるリポソーム凝集作用の解明2021

    • Author(s)
      陳瀟逸,植草義徳,中山勉,木内文之,菊地晴久
    • Organizer
      第17回日本カテキン学会年次学術大会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] NMRを用いたテアフラビン類とリン脂質膜との相互作用解析(第2報)2021

    • Author(s)
      陳 瀟逸、植草 義徳、中山 勉、木内 文之
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-18K05525
  • [Presentation] テアフラビン類とリン脂質膜との分子間相互作用解析2021

    • Author(s)
      陳瀟逸,植草義徳,中山勉,木内文之,菊地晴久
    • Organizer
      日本生薬学会第67回年会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] NMRを用いたテアフラビン類とリン脂質膜との相互作用解析(第2報)2020

    • Author(s)
      陳瀟逸,植草義徳,中山勉,木内文之
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] Caco-2細胞を用いたフラボン類の細胞透過性とリン脂質膜親和性及び抗炎症作用の連関2020

    • Author(s)
      遠周直人,植草義徳,木内文之
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] NMRを用いたテアフラビン類とリン脂質膜との相互作用解析2020

    • Author(s)
      陳 瀟逸,植草 義徳,中山 勉,木内 文之
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-18K05525
  • [Presentation] NMRを用いたテアフラビン類とリン脂質膜との相互作用解析2020

    • Author(s)
      陳瀟逸,植草義徳,中山勉,木内文之.
    • Organizer
      日本薬学会第140回年会
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] Structural analysis of the complex of baicalin and berberine in aqueous solution2019

    • Author(s)
      Yoshinori Uekusa, Riina Tsutsumi, Kenjiro Nakamoto, and Fumiyuki Kiuchi
    • Organizer
      American Society of Pharmacognosy 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06734
  • [Presentation] Structural analysis of the complex of baicalin and berberine in aqueous solution2019

    • Author(s)
      Uekusa, Y., Tsutsumi, R., Nakamoto, K., and Kiuchi, F.
    • Organizer
      American Society of Pharmacognosy 2019 Annual Meeting (ASP2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] テアフラビン類の抗炎症作用とリン脂質膜に対する親和性の評価2019

    • Author(s)
      植草 義徳,陳 瀟逸,鰐口 あおい,倉田 幸一,中山 勉,木内 文之
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K05525
  • [Presentation] Solubility-enhancement of berberine-baicalin complex by crocins”, American Society of Pharmacognosy 2019 Annual Meeting (ASP2019),2019

    • Author(s)
      Okoshi, K., Uekusa, Y., Narukawa, Y., and Kiuchi, F.
    • Organizer
      American Society of Pharmacognosy 2019 Annual Meeting (ASP2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07138
  • [Presentation] メタボローム解析を用いたチンピの品質評価に関する研究2018

    • Author(s)
      八汐 祥恵,鰐口 あおい,二見 萌,植草 義徳,河野徳昭,渕野 裕之,川原 信夫,木内 文之
    • Organizer
      日本生薬学会第65回年会
    • Data Source
      KAKENHI-PROJECT-18K06734
  • 1.  Kiuchi Fumiyuki (60161402)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 2.  NAKAYAMA Tsutomu (50150199)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  奈良井 朝子 (00339475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  飯嶋 益巳 (40390728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  吉田 将人 (80511906)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  岩崎 有紘 (00754897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  成川 佑次
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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