Ohshima Jun 大嶋淳

Researcher Number	30755450
Other IDs
Affiliation (Current)	2025: 大阪大学, 歯学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 大阪大学, 歯学部附属病院, 講師 2018 – 2019: 大阪大学, 歯学研究科, 助教 2016: 大阪大学, 歯学研究科, 助教 2015: 大阪大学, 歯学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Conservative dentistry Except Principal Investigator Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 歯学 / 微生物学 / 口腔細菌学 / 免疫学 / インターフェロン / 口腔感染症 / 上皮間葉転換 / 感染症 / 細菌 / 微生物 … More Except Principal Investigator … More 免疫学 / 口腔細菌学 / 微生物学 / 歯学 / 大腸癌 Less

網羅的遺伝子解析による口腔細菌の異所性定着機構の解明
- Principal Investigator
  
  林美加子
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Comprehensive analysis of host signaling infected by periodontopathogenic bacteria.Principal Investigator
- Principal Investigator
  
  大嶋淳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Establishment of genetic analysis method for Fusobacterium nucleatum
- Principal Investigator
  
  Hayashi Mikako
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Elucidation of mechanisms of host immunosuppression by periodontal pathogenic bacteriaPrincipal Investigator
- Principal Investigator
  
  Ohshima Jun
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Mechanism of induction of epithelial-mesenchymal transition by periodontal pathogenic bacteriaPrincipal Investigator
- Principal Investigator
  
  Ohshima Jun
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Role of IFN-gamma in elimination of intracellularly invaded oral bacteria and disease progression.Principal Investigator
- Principal Investigator
  
  Ohshima Jun
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2015

All Journal Article Presentation

[Journal Article] Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial2023
- Author(s)
  Yahata Yoshio、Handa Keisuke、Ohkura Naoto、Okamoto Motoki、Ohshima Jun、Itoh Shusaku、Kawashima Nobuyuki、Tanaka Toshinori、Sato Nobuya、Noiri Yuichiro、Hayashi Mikako、Okiji Takashi、Saito Masahiro
- Journal Title
  
  Regenerative Therapy
  
  Volume: 24 Pages: 377-384
- DOI
  10.1016/j.reth.2023.08.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10147, KAKENHI-PROJECT-22K09980, KAKENHI-PROJECT-21K09944, KAKENHI-PROJECT-21K19587, KAKENHI-PROJECT-21H03116
[Journal Article] Novel Functional Peptide for Next-Generation Vital Pulp Therapy2022
- Author(s)
  Watanabe M.、Okamoto M.、Komichi S.、Huang H.、Matsumoto S.、Moriyama K.、Ohshima J.、Abe S.、Morita M.、Ali M.、Takebe K.、Kozaki I.、Fujimoto A.、Kanie K.、Kato R.、Uto K.、Ebara M.、Yamawaki-Ogata A.、Narita Y.、Takahashi Y.、Hayashi M.
- Journal Title
  
  Journal of Dental Research
  
  Volume: 102 Issue: 3 Pages: 322-330
- DOI
  10.1177/00220345221135766
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09980, KAKENHI-PROJECT-20H00552, KAKENHI-PROJECT-20K05227, KAKENHI-PROJECT-21K09915, KAKENHI-PROJECT-21K19598, KAKENHI-PROJECT-21K16967, KAKENHI-PROJECT-23K24526
[Journal Article] Streptococcus gordoniiprograms epithelial cells to resist ZEB2 induction byPorphyromonas gingivalis2019
- Author(s)
  Ohshima Jun、Wang Qian、Fitzsimonds Zackary R.、Miller Daniel P.、Sztukowska Maryta N.、Jung Young-Jung、Hayashi Mikako、Whiteley Marvin、Lamont Richard J.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 17 Pages: 8544-8553
- DOI
  10.1073/pnas.1900101116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17066
[Journal Article] Porphyromonas gingivalis Tyrosine Phosphatase Php1 Promotes Community Development and Pathogenicity2019
- Author(s)
  Jung Young-Jung、Miller Daniel P.、Perpich John D.、Fitzsimonds Zackary R.、Shen Daonan、Ohshima Jun、Lamont Richard J.
- Journal Title
  
  mBio
  
  Volume: 10 Issue: 5
- DOI
  10.1128/mbio.02004-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17066
[Journal Article] RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.2015
- Author(s)
  Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 112 Issue: 33
- DOI
  10.1073/pnas.1510031112
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26117713, KAKENHI-PROJECT-15H04745, KAKENHI-PROJECT-15H06382
[Journal Article] mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells.2015
- Author(s)
  Ito D, Nojima S*, Nishide M, Okuno T, Takamatsu H, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Hosokawa T, Toyofuku T, Ohshima J, Kamimura D, Yamamoto M, Murakami M, Morii E, Rakugi H, Isaka Y, Kumanogoh A*. (* correspondence)
- Journal Title
  
  J Immunol.
  
  Volume: 195 Issue: 3 Pages: 934-943
- DOI
  10.4049/jimmunol.1403038
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08423, KAKENHI-PROJECT-26461293, KAKENHI-PROJECT-15H06382, KAKENHI-PROJECT-25860357
[Journal Article] p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.2015
- Author(s)
  Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, Yamamoto M
- Journal Title
  
  Cell Rep
  
  Volume: 13 Issue: 2 Pages: 223-233
- DOI
  10.1016/j.celrep.2015.09.005
- NAID
  120007001422
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14951, KAKENHI-PROJECT-15K15122, KAKENHI-PUBLICLY-15H01377, KAKENHI-PUBLICLY-15H01380, KAKENHI-PUBLICLY-26111514, KAKENHI-PROJECT-15H06382, KAKENHI-PROJECT-26713005
[Presentation] Immune response in the interaction between periodontopathic bacteria and host cells.2023
- Author(s)
  大嶋　淳
- Organizer
  第71回国際歯科研究学会日本部会(JADR)総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K09980
[Presentation] Porphyromonas gingivalisによる免疫抑制メカニズムの解明2023
- Author(s)
  阿部翔大郎, 大嶋淳, 森田真吉, 田中伸武, 林美加子
- Organizer
  第135回大阪大学歯学会例会
- Data Source
  KAKENHI-PROJECT-22K09980
[Presentation] Fusobacterium nucleatumが宿主免疫細胞の非標準的インフラマソームに与える影響2023
- Author(s)
  森田真吉、大嶋淳、阿部翔大郎、田中伸武、林　美加子
- Organizer
  第159回日本歯科保存学会秋季学術大会
- Data Source
  KAKENHI-PROJECT-22K09980
[Presentation] Porphyromonas gingivalisはインターフェロンシグナルを抑制する2021
- Author(s)
  阿部翔大郎、大嶋淳、森田真吉、林美加子
- Organizer
  第155回日本歯科保存学会 2021年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-20K18507
[Presentation] Porphyromonas gingivalisはβ-カテニンシグナルを介して歯肉上皮細胞に上皮間葉転換を誘導する2021
- Author(s)
  大嶋　淳
- Organizer
  第94回日本細菌学会総会　細菌学若手コロッセウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K18507
[Presentation] Porphyromonas gingivalis induces mesenchymal-like transition through beta-catenin signaling.2020
- Author(s)
  Jun Ohshima
- Organizer
  Joint Research Symposium of Osaka University and Newcastle University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18507
[Presentation] Streptococcus gordonii antagonizes Porphyromonas gingivalis-mediated signaling in epithelial cells.2019
- Author(s)
  Fitzsimonds ZR, Ohshima J, Wang Q, Sztukowska MN, Miller DP, Lamont RJ.
- Organizer
  97th International Association for Dental Research General Session.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17066
[Presentation] Porphyromonas gingivalis induces mesenchymal-like transition through beta-catenin signaling.2019
- Author(s)
  Ohshima J, Hayashi M, Lamont RJ.
- Organizer
  97th International Association for Dental Research General Session.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17066
[Presentation] Porphyromonas gingivalis はβ-カテニンシグナルを介して歯肉上皮細胞に上皮間葉転換を誘導する2018
- Author(s)
  大嶋淳、林美加子
- Organizer
  第148回日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-18K17066
[Presentation] p62 plays a specific role in IFN-g-induced presentation of a Toxoplasma vacuolar antigen.2015
- Author(s)
  Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, and Yamamoto M.
- Organizer
  Forum Cheju17
- Place of Presentation
  Taniguchi Memorial Hall, Research Institute for Microbial Diseases, Osaka University（大阪府吹田市）
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06382
[Presentation] RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.2015
- Author(s)
  Sasai M, Ohshima J, Ma JS, Lee Y, Takeda K, Yamamoto M.
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15H06382
[Presentation] p62 plays a specific role in IFN-g-induced presentation of a Toxoplasma vacuolar antigen.2015
- Author(s)
  Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, and Yamamoto M.
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15H06382
[Presentation] Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.2015
- Author(s)
  Ma JS, Sasai M, Ohshima J, Lee Y, Bando H, Takeda K, and Yamamoto M.
- Organizer
  Forum Cheju17
- Place of Presentation
  Taniguchi Memorial Hall, Research Institute for Microbial Diseases, Osaka University（大阪府吹田市）
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06382

1. Hayashi Mikako (40271027)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 山口幹代 (30523089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SAITOH Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 大倉直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 大島勇人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 山本雅裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 熊郷淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 野島聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohshima Jun 大嶋 淳

Research Projects

Research Products

Co-Researchers

網羅的遺伝子解析による口腔細菌の異所性定着機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of host signaling infected by periodontopathogenic bacteria.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of genetic analysis method for Fusobacterium nucleatum

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanisms of host immunosuppression by periodontal pathogenic bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of induction of epithelial-mesenchymal transition by periodontal pathogenic bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of IFN-gamma in elimination of intracellularly invaded oral bacteria and disease progression.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel Functional Peptide for Next-Generation Vital Pulp Therapy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Streptococcus gordoniiprograms epithelial cells to resist ZEB2 induction byPorphyromonas gingivalis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Porphyromonas gingivalis Tyrosine Phosphatase Php1 Promotes Community Development and Pathogenicity2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Immune response in the interaction between periodontopathic bacteria and host cells.2023

Author(s)

Organizer

Data Source

Ohshima Jun 大嶋淳

[Presentation] Porphyromonas gingivalis はβ-カテニンシグナルを介して歯肉上皮細胞に上皮間葉転換を誘導する2018