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Hamamura Kengo  濱村 賢吾

Researcher Number 30756466
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9146-8554
Affiliation (Current) 2022: 第一薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2021: 第一薬科大学, 薬学部, 講師
2015 – 2020: 第一薬科大学, 薬学部, 助教
Review Section/Research Field
Principal Investigator
Applied health science / Pain science / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 59040:Nutrition science and health science-related
Keywords
Principal Investigator
エクソソーム / 神経障害性疼痛 / ホルマリン誘発性侵害刺激行動 / ホルマリン誘発侵害刺激行動 / 疼痛 / ホルマリンテスト
  • Research Projects

    (4 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (19 People)
  •  Focusing on the lipid bilayer of exosomes as a potential new therapeutic target for neuropathic pain.Principal Investigator

    • Principal Investigator
      濱村 賢吾
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Daiichi University, College of Pharmaceutical Sciences
  •  Role of exosomes in the aggravation of neuropathic painPrincipal Investigator

    • Principal Investigator
      Hamamura Kengo
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Daiichi University, College of Pharmaceutical Sciences
  •  Identification of pain aggravating factors on the surface protein of exosomes, and creation of new pain treatment strategiesPrincipal Investigator

    • Principal Investigator
      HAMAMURA Kengo
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied health science
      Pain science
    • Research Institution
      Daiichi University, College of Pharmaceutical Sciences
  •  Novel enhancement mechanisms of the nociceptive response by serum exosomes in a mouse model of neuropathic painPrincipal Investigator

    • Principal Investigator
      Hamamura Kengo
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Applied health science
    • Research Institution
      Daiichi University, College of Pharmaceutical Sciences

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Preclinical Characterization of Antinociceptive Effect of Bergamot Essential Oil and of Its Fractions for Rational Translation in Complementary Therapy2022

    • Author(s)
      Scuteri Damiana、Rombol Laura、Crudo Michele、Watanabe Chizuko、Mizoguchi Hirokazu、Sakurada Shinobu、Hamamura Kengo、Sakurada Tsukasa、Tonin Paolo、Corasaniti Maria Tiziana、Bagetta Giacinto
    • Journal Title

      Pharmaceutics

      Volume: 14 Pages: 312-312

    • DOI

      10.3390/pharmaceutics14020312

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11613
  • [Journal Article] Alteration of circadian machinery in monocytes underlies chronic kidney disease-associated cardiac inflammation and fibrosis2021

    • Author(s)
      Yoshida Yuya、Matsunaga Naoya、Nakao Takaharu、Hamamura Kengo、Kondo Hideaki、Ide Tomomi、Tsutsui Hiroyuki、Tsuruta Akito、Kurogi Masayuki、Nakaya Michio、Kurose Hitoshi、Koyanagi Satoru、Ohdo Shigehiro
    • Journal Title

      Nature Communications

      Volume: 12 Pages: 2783-2783

    • DOI

      10.1038/s41467-021-23050-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-21K11613
  • [Journal Article] Efficacy of Essential Oils in Pain: A Systematic Review and Meta-Analysis of Preclinical Evidence2021

    • Author(s)
      Scuteri Damiana、Hamamura Kengo、Sakurada Tsukasa、Watanabe Chizuko、Sakurada Shinobu、Morrone Luigi Antonio、Rombol Laura、Tonin Paolo、Bagetta Giacinto、Corasaniti Maria Tiziana
    • Journal Title

      Frontiers in Pharmacology

      Volume: 12 Pages: 640128-640128

    • DOI

      10.3389/fphar.2021.640128

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16936
  • [Journal Article] Development and Translation of NanoBEO, a Nanotechnology-Based Delivery System of Bergamot Essential Oil Deprived of Furocumarins, in the Control of Agitation in Severe Dementia2021

    • Author(s)
      Scuteri D、Cassano R、Trombino S、Russo R、Mizoguchi H、Watanabe C、Hamamura K、Katsuyama S、Komatsu T、Morrone L A、Rombol L、Adornetto A、Lagan A S、Corasaniti M T、Tonin P、Sakurada S、Sakurada T、Nicotera P、Bagetta G
    • Journal Title

      Pharmaceutics

      Volume: 13 Pages: 379-379

    • DOI

      10.3390/pharmaceutics13030379

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07381, KAKENHI-PROJECT-19K16936
  • [Journal Article] Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design2021

    • Author(s)
      Yokoo Hidetomo、Shibata Norihito、Endo Akinori、Ito Takahito、Yanase Yuta、Murakami Yuki、Fujii Kiyonaga、Hamamura Kengo、Saeki Yasushi、Naito Mikihiko、Aritake Kosuke、Demizu Yosuke
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 64 Pages: 15868-15882

    • DOI

      10.1021/acs.jmedchem.1c01206

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-18K07311, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-21K11613, KAKENHI-PROJECT-20K22711
  • [Journal Article] Exploitation of Thermal Sensitivity and Hyperalgesia in a Mouse Model of Dystonia2021

    • Author(s)
      Scuteri Damiana、Rombol Laura、Natoli Silvia、Pisani Antonio、Bonsi Paola、Hamamura Kengo、Bagetta Giacinto、Tonin Paolo、Corasaniti Maria Tiziana
    • Journal Title

      Life

      Volume: 11 Pages: 985-985

    • DOI

      10.3390/life11090985

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11613
  • [Journal Article] Analgesic Effects of PREGABALIN OD TABLETS “NIPRO” in a Mouse Model of Neuropathic Pain2020

    • Author(s)
      Hamamura Kengo、Katsuyama Soh、Komatsu Takaaki、Scuteri Damiana、Bagetta Giacinto、Aritake Kosuke、Sakurada Tsukasa
    • Journal Title

      Journal of New Remedies & Clinics

      Volume: 69 Pages: 1441-1450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K16936
  • [Journal Article] Circadian expression of Glycoprotein 2 (Gp2) gene is controlled by a molecular clock in mouse Peyer's patches2020

    • Author(s)
      Kusunose Naoki、Tsuruta Akito、Hamamura Kengo、Tsurudome Yuya、Yoshida Yuya、Akamine Takahiro、Matsunaga Naoya、Koyanagi Satoru、Ohdo Shigehiro
    • Journal Title

      Genes to Cells

      Volume: 25 Pages: 270-278

    • DOI

      10.1111/gtc.12758

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16936
  • [Journal Article] Behavioral Effects of Continuously Administered Bergamot Essential Oil on Mice With Partial Sciatic Nerve Ligation2020

    • Author(s)
      Hamamura Kengo、Katsuyama Soh、Komatsu Takaaki、Scuteri Damiana、Bagetta Giacinto、Aritake Kosuke、Sakurada Tsukasa
    • Journal Title

      Frontiers in Pharmacology

      Volume: 11 Pages: 1310-1310

    • DOI

      10.3389/fphar.2020.01310

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16936
  • [Journal Article] Role of 5-HT1A Receptor in the Anxiolytic-Relaxant Effects of Bergamot Essential Oil in Rodent2020

    • Author(s)
      Rombol Laura、Scuteri Damiana、Watanabe Chizuko、Sakurada Shinobu、Hamamura Kengo、Sakurada Tsukasa、Tonin Paolo、Corasaniti Maria Tiziana、Bagetta Giacinto、Morrone Luigi Antonio
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 2597-2597

    • DOI

      10.3390/ijms21072597

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16936
  • [Journal Article] Angiotensin-II regulates dosing time-dependent intratumoral accumulation of macromolecular drug formulations via 24-h blood pressure rhythm in tumor-bearing mice2018

    • Author(s)
      Matsunaga Takashi、Matsunaga Naoya、Kusunose Naoki、Ikeda Eriko、Okazaki Hiroyuki、Kakimoto Keisuke、Hamamura Kengo、Koyanagi Satoru、Ohdo Shigehiro
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 498 Pages: 86-91

    • DOI

      10.1016/j.bbrc.2017.11.162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16972, KAKENHI-PROJECT-17K18298
  • [Journal Article] Possible involvement of the peripheral μ-opioid system in antinociception induced by bergamot essential oil to allodynia after peripheral nerve injury.2018

    • Author(s)
      Komatsu Takaaki、Katsuyama Soh、Uezono Yasuhito、Sakurada Chikai、Tsuzuki Minoru、Hamamura Kengo、Bagetta Giacinto、Sakurada Shinobu、Sakurada Tsukasa
    • Journal Title

      Neurosci Lett

      Volume: 686 Pages: 127-132

    • DOI

      10.1016/j.neulet.2018.08.053

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07381, KAKENHI-PROJECT-18K07404, KAKENHI-PROJECT-17K18298
  • [Journal Article] The involvement of spinal release of histamine on nociceptive behaviors induced by intrathecally administered spermine2017

    • Author(s)
      Mizoguchi H, Watanabe C, Hayashi T, Iwata Y, Watanabe H, Katsuyama S, Hamamura K, Sakurada T, Ohtsu H, Yanai K, Sakurada S.
    • Journal Title

      European Journal of Pharmacology

      Volume: 800 Pages: 9-15

    • DOI

      10.1016/j.ejphar.2017.01.031

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06795, KAKENHI-PROJECT-15K08678
  • [Journal Article] Alterations of Hepatic Metabolism in Chronic Kidney Disease via D-box-binding Protein Aggravate the Renal Dysfunction.2016

    • Author(s)
      Hamamura K, Matsunaga N, Ikeda E, Kondo H, Ikeyama H, Tokushige K, Itcho K, Furuichi Y, Yoshida Y, Matsuda M, Yasuda K, Doi A, Yokota Y, Amamoto T, Aramaki H, Irino Y, Koyanagi S, Ohdo S.
    • Journal Title

      J Biol Chem

      Volume: 291 Pages: 4913-4927

    • DOI

      10.1074/jbc.m115.696930

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H06795, KAKENHI-PROJECT-25253038
  • [Journal Article] Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression.2016

    • Author(s)
      Okazaki F, Matsunaga N, Okazaki H, Azuma H, Hamamura K, Tsuruta A, Tsurudome Y, Ogino T, Hara Y, Suzuki T, Hyodo K, Ishihara H, Kikuchi H, To H, Aramaki H, Koyanagi S, Ohdo S
    • Journal Title

      J Biol Chem.

      Volume: 291 Pages: 7017-7028

    • DOI

      10.1074/jbc.m115.713412

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19167, KAKENHI-PROJECT-15H06795, KAKENHI-PROJECT-26860097, KAKENHI-PROJECT-25253038
  • [Journal Article] Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease.2016

    • Author(s)
      Matsunaga N, Ikeda E, Kakimoto K, Watanabe M, Shindo N, Tsuruta A, Ikeyama H, Hamamura K, Higashi K, Yamashita T, Kondo H, Yoshida Y, Matsuda M, Ogino T, Tokushige K, Itcho K, Furuichi Y, Nakao T, Yasuda K, Doi A, Amamoto T, Aramaki H, Tsuda M, Inoue K, Ojida A, Koyanagi S, Ohdo S
    • Journal Title

      EBioMedicine

      Volume: 13 Pages: 262-273

    • DOI

      10.1016/j.ebiom.2016.10.008

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-16H02636, KAKENHI-PROJECT-15H06795
  • [Journal Article] Mitomycin C modulates the circadian oscillation of clock gene period 2 expression through attenuating the glucocorticoid signaling in mouse fibroblasts.2015

    • Author(s)
      Kusunose N, Matsunaga N, Kimoto K, Akamine T, Hamamura K, Koyanagi S, Ohdo S, Kubota T.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 467 Pages: 157-163

    • DOI

      10.1016/j.bbrc.2015.09.086

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H06795, KAKENHI-PROJECT-26861456
  • [Presentation] Formalin-induced nociceptive response is enhanced by serum exosomes isolated from partial sciatic nerve ligation (PSL) mice.2019

    • Author(s)
      Hamamura K, Katsuyama S, Komatsu T, Sakurada T, Aritake K.
    • Organizer
      Society for Neuroscience (SfN) Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16936
  • [Presentation] Novel enhancement mechanisms of the nociceptive response by serum exosomes in a mouse model of neuropathic pain2018

    • Author(s)
      Hamamura Kengo、Katsuyama Soh、Toyofuku Yohei、Watanabe Shunpei、Nishimura Yuri、Sueishi Nanami、Tanaka Taisei、Komatsu Takaaki、Sakurada Tsukasa、Aritake Kosuke
    • Organizer
      WCP2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18298
  • [Presentation] Novel enhancement mechanisms of the nociceptive response by serum exosomes in a mouse model of neuropathic pain2017

    • Author(s)
      Kengo Hamamura、Soh Katsuyama、Yohei Toyofuku、Shunpei Watanabe、Yuri Nishimura、Nanami Sueishi、Taisei Tanaka、Takaaki Komatsu、Tsukasa Sakurada、Kosuke Aritake
    • Organizer
      The 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Data Source
      KAKENHI-PROJECT-17K18298
  • [Presentation] Serum exosomes in a mouse model of neuropathic pain enhance the formalin-induced nociceptive response2016

    • Author(s)
      Kengo Hamamura, Naoki Kusunose, Soh Katsuyama, Takaaki Komatsu, Tsukasa Sakurada
    • Organizer
      16th World Congress on Pain
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2016-09-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06795
  • 1.  MIZOGUCHI Hirokazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  WATANABE Chizuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  NAKAYA Michio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  MATSUNAGA Naoya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 5.  SAEKI Yasushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  櫻田 忍
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  楠瀬 直喜
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  小柳 悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 9.  大戸 茂弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 10.  岡崎 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  岡崎 史泰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  出水 庸介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  柴田 識人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  内藤 幹彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  伊藤 拓水
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  遠藤 彬則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  上園 保仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  井上 和秀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  津田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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