Chaki Tomohiro 茶木友浩

Researcher Number	30758701
Other IDs	https://orcid.org/0000-0001-8898-3977
Affiliation (Current)	2025: 札幌医科大学, 医学部, 訪問研究員
Affiliation (based on the past Project Information) *help	2025: 札幌医科大学, 医学部, 訪問研究員 2020 – 2025: 札幌医科大学, 医学部, 助教 2017 – 2019: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Emergency medicine Except Principal Investigator Basic Section 55050:Anesthesiology-related / Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator 脳腸相関 / 腸内細菌叢 / 幼若脳麻酔薬神経毒性 / シンバイオティックス / プロバイオティックス / 幼若脳 / 麻酔薬神経毒生 / 学習能力障害 / 短鎖脂肪酸 / ミクログリア … More / アポトーシス / 神経炎症 / 糞便細菌叢移植 / 酪酸 / 麻酔薬神経毒性 / エピジェネティックス / BDNF / 学習障害 / 酸化ストレス / 骨格筋障害 / 脂質過酸化反応 / 脂肪製剤 / プロポフォール注入症候群 / プロポフォール … More Except Principal Investigator 腸内細菌叢 / 麻酔薬 / 薬物胎盤移行性 / 宮入菌 / 短鎖脂肪酸 / 腸脳相関 / 外傷性脳損傷 / 麻酔管理戦略 / 周術期関連薬 / LM11A-31 / 低親和性神経成長因子受容体 / 術後認知機能障害 / 小児麻酔 / 脳腸軸 / AIDN / 麻酔誘発性発達神経毒性 / 胎盤移行性 / トランスポーター / レミマゾラム / 血液胎盤関門モデル Less

トランスポーターの機能修飾を介して麻酔薬の胎盤移行性を制御する母体管理戦略の探究
- Principal Investigator
  
  佐藤慧
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
宮入菌による外傷性脳損傷モデルマウスの中枢神経障害抑制の検証
- Principal Investigator
  
  齋藤光汰
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Sapporo Medical University
Preventive effect of tributyrin on remimazolam-induced learning impairment
- Principal Investigator
  
  平畑知輝
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
The effect of synbiotics on developmental anesthetic neurotoxicityPrincipal Investigator
- Principal Investigator
  
  茶木友浩
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
低親和性神経成長因子受容体選択的リガンド：LM11A-31による術後認知機能障害予防戦略
- Principal Investigator
  
  山蔭道明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
トランスポーター機能の修飾を介した麻酔薬の胎盤移行性制御の探究
- Principal Investigator
  
  佐藤慧
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
The influence of microbiota to neurotoxicity of general anesthesia for developing brainPrincipal Investigator
- Principal Investigator
  
  Chaki Tomohiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Sapporo Medical University
The mechanism of propofol infusion syndrome - the potency of dexmedetomidine as a treatment or prevention of propofol infusion syndromePrincipal Investigator
- Principal Investigator
  
  Chaki Tomohiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Sapporo Medical University

All 2024 2023 2022 2019 2018 2017

All Journal Article Presentation

[Journal Article] Fecal microbiota transplantation improves spatial learning disability caused by developmental anesthetic neurotoxicity in neonatal rats2024
- Author(s)
  Chaki Tomohiro、Horiguchi Yuri、Tachibana Shunsuke、Sato Satoshi、Hirahata Tomoki、Nishihara Noriaki、Kii Natsumi、Yoshikawa Yusuke、Hayamizu Kengo、Yamakage Michiaki
- Journal Title
  
  ResearchSquare
  
  Volume: -
- DOI
  10.21203/rs.3.rs-3910445/v1
- Data Source
  KAKENHI-PROJECT-20K17786
[Journal Article] Lipid emulsion, but not propofol, induces skeletal muscle damage and lipid peroxidation.2019
- Author(s)
  Chaki T, Hirata N, Yoshikawa Y, Tachibana S, Tokinaga Y, Yamakage M
- Journal Title
  
  Journal of anesthesia
  
  Volume: 33 Issue: 6 Pages: 628-635
- DOI
  10.1007/s00540-019-02676-8
- NAID
  40022092542
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17059
[Presentation] Establishment of an in vitro human blood-placental barrier model and verification of remimazolam permeability2023
- Author(s)
  Satoshi Sato, Tomohiro Chaki, Tomoki Hirahata, Tsuyoshi Aoyama, Takaki Toda, Michiaki Yamakage
- Organizer
  Euroanaesthesia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09075
[Presentation] Establishment of an in vitro human blood-placental barrier model and verification of remimazolam permeability2023
- Author(s)
  Satoshi Sato, Tomohiro Chaki, Tomoki Hirahata, Tsuyoshi Aoyama, Takaki Toda, Michiaki Yamakage
- Organizer
  Euroanaesthesia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09075
[Presentation] In vitroヒト血液胎盤関門モデルの作成とレミマゾラム移行性の検証2023
- Author(s)
  佐藤　慧，茶木友浩，平畑知輝，青山　剛，戸田貴大，山蔭道明
- Organizer
  日本麻酔科学会第70回学術集会
- Data Source
  KAKENHI-PROJECT-22K09075
[Presentation] in vitroヒト血液胎盤関門モデルの作成とレミマゾラム移行性の検証2023
- Author(s)
  佐藤　慧，茶木友浩，平畑知輝，青山　剛，戸田貴大，山蔭道明
- Organizer
  日本麻酔科学会第70回学術集会
- Data Source
  KAKENHI-PROJECT-22K09075
[Presentation] 新規ベンゾジアゼピン系薬レミマゾラム及びその代謝物の血漿中濃度同時測定法2022
- Author(s)
  村岡　愛，市川凌史，青山　剛，佐藤　慧，茶木友浩，立花俊祐，山蔭道明，戸田貴大
- Organizer
  第142回日本薬学会年次会
- Data Source
  KAKENHI-PROJECT-22K09075
[Presentation] ヒト血漿中のレミマゾラムと代謝物（CNS7054）を同時定量可能とする液体クロマトグラフ-タンデム質量分析法の確立2022
- Author(s)
  佐藤　慧，村岡　愛，市川凌史，茶木友浩，戸田貴大，山蔭道明
- Organizer
  日本麻酔科学会第69回学術集会
- Data Source
  KAKENHI-PROJECT-22K09075
[Presentation] Lipid, A Solvent of Propofol, Induces Muscle Wasting via Oxidative Stress2018
- Author(s)
  茶木　友浩
- Organizer
  アメリカ麻酔学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17059
[Presentation] プロポフォールの溶媒である脂肪製剤は酸化ストレスを介して横紋筋障害を引き起こす2017
- Author(s)
  茶木友浩
- Organizer
  日本麻酔科学会北海道・東北支部第7回学術集会
- Data Source
  KAKENHI-PROJECT-17K17059

1. 佐藤慧 (90884346)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. 平畑知輝 (00966301)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. 齋藤光汰 (60999902)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 山蔭道明 (70285005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Chaki Tomohiro 茶木 友浩

Research Projects

Research Products

Co-Researchers

トランスポーターの機能修飾を介して麻酔薬の胎盤移行性を制御する母体管理戦略の探究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

宮入菌による外傷性脳損傷モデルマウスの中枢神経障害抑制の検証

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preventive effect of tributyrin on remimazolam-induced learning impairment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of synbiotics on developmental anesthetic neurotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

低親和性神経成長因子受容体選択的リガンド：LM11A-31による術後認知機能障害予防戦略

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

トランスポーター機能の修飾を介した麻酔薬の胎盤移行性制御の探究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The influence of microbiota to neurotoxicity of general anesthesia for developing brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of propofol infusion syndrome - the potency of dexmedetomidine as a treatment or prevention of propofol infusion syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Fecal microbiota transplantation improves spatial learning disability caused by developmental anesthetic neurotoxicity in neonatal rats2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipid emulsion, but not propofol, induces skeletal muscle damage and lipid peroxidation.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Establishment of an in vitro human blood-placental barrier model and verification of remimazolam permeability2023

Author(s)

Organizer

Data Source

[Presentation] Establishment of an in vitro human blood-placental barrier model and verification of remimazolam permeability2023

Author(s)

Organizer

Data Source

[Presentation] In vitroヒト血液胎盤関門モデルの作成とレミマゾラム移行性の検証2023

Author(s)

Organizer

Data Source

[Presentation] in vitroヒト血液胎盤関門モデルの作成とレミマゾラム移行性の検証2023

Author(s)

Organizer

Data Source

[Presentation] 新規ベンゾジアゼピン系薬レミマゾラム及びその代謝物の血漿中濃度同時測定法2022

Chaki Tomohiro 茶木友浩