Umemura Atsushi 楳村敦詩

Researcher Number	30759585
Affiliation *help	2016 – 2018 : 京都府立医科大学, 医学（系）研究科（研究院）, 助教 2015 – 2016 : 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Tumor biology
Keywords	Principal Investigator p62 / 肝細胞癌 / 癌 / シグナル伝達 / mTOR / 医療・福祉 / 肝癌 / NRF2

The role of p62 in the HCC initiation and progressionPrincipal Investigator
- Principal Investigator
  
  Umemura Atsushi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2017 2016 2015

All Journal Article Presentation

[Journal Article] p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.2017
- Author(s)
  Gen Y, Yasui K, Kitaichi T, Iwai N, Terasaki K, Dohi O, Hashimoto H, Fukui H, Inada Y, Fukui A, Jo M, Moriguchi M, Nishikawa T, Umemura A, Yamaguchi K, Konishi H, Naito Y, Itoh Y.
- Journal Title
  
  Cancer Lett.
  
  Volume : 398 Pages : 52-61
- DOI
  10.1016/j.canlet.2017.04.002
- Peer Reviewed / Int'l Joint Research / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09017, KAKENHI-PROJECT-16K10512, KAKENHI-PROJECT-15H06547
[Journal Article] Hepatic nucleotide binding oligomerization domain-like receptors pyrin domain-containing 3 inflammasomes are associated with the histologic severity of non-alcoholic fatty liver disease.2017
- Author(s)
  Mitsuyoshi H, Yasui K, Hara T, Taketani H, Ishiba H, Okajima A, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Minami M, Itoh Y.
- Journal Title
  
  Hapatology Research
  
  Volume : -
- DOI
  10.1111/hepr.12883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06547, KAKENHI-PROJECT-26461016, KAKENHI-PROJECT-15K09017
[Journal Article] Development of hepatocellular carcinoma in Japanese patients with biopsy-proven non-alcoholic fatty liver disease: Association between PNPLA3 genotype and hepatocarcinogenesis/fibrosis progression.2016
- Author(s)
  Seko Y, Sumida Y, Tanaka S, Mori K, Taketani H, Ishiba H, Hara T, Okajima A, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Kanemasa K, Yasui K, Imai S, Shimada K, Itoh Y.
- Journal Title
  
  Hepatol Res
  
  Volume : -
- DOI
  10.1111/hepr.12840
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06547, KAKENHI-PROJECT-15K09017
[Journal Article] Current status and future prospects of chemotherapy for advanced hepatocellular carcinoma.2016
- Author(s)
  Moriguchi M, Umemura A, Itoh Y.
- Journal Title
  
  Clin J Gastroenterol
  
  Volume : 9 Pages : 184-190
- DOI
  10.1007/s12328-016-0670-7
- Data Source
  KAKENHI-PROJECT-15H06547
[Journal Article] 肝細胞癌とオートファジー2016
- Author(s)
  楳村敦詩、山口寛二、Michael Karin、伊藤義人
- Journal Title
  
  肝胆膵
  
  Volume : 73 Pages : 201-206
- Data Source
  KAKENHI-PROJECT-15H06547
[Journal Article] NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.2016
- Author(s)
  Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR,McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M.
- Journal Title
  
  Cell
  
  Volume : 164(5) Pages : 896-910
- DOI
  10.1016/j.cell.2015.12.057
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06547
[Journal Article] Genome-wide DNA methylation analysis in hepatocellular carcinoma.2016
- Author(s)
  Yamada N, Yasui K, Dohi O, Gen Y, Tomie A, Kitaichi T, Iwai N, Mitsuyoshi H, Sumida Y, Moriguchi M, Yamaguchi K, Nishikawa T, Umemura A, Naito Y, Tanaka S, Arii S, Itoh Y.
- Journal Title
  
  Oncology Reports
  
  Volume : 35 Pages : 2228-2236
- DOI
  10.3892/or.2016.4619
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09017, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H06547
[Presentation] The Effect of mTORC1 Inhibition on NAFLD and subsequent HCC Development2016
- Author(s)
  Atsushi Umemura, Yoshito Itoh, Michael Karin.
- Organizer
  The international congress 2016, European Association for the Study of the Liver (EASL)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2016-04-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06547
[Presentation] 肝発癌・進展における，mTORC1およびp62-Nrf2シグナルの役割2016
- Author(s)
  楳村敦詩、山口寛二、伊藤義人
- Organizer
  第52回日本肝臓学会総会（幕張）
- Place of Presentation
  幕張
- Year and Date
  2016-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06547
[Presentation] 肝癌および慢性肝疾患の病態におけるmTORC1阻害の影響2015
- Author(s)
  楳村敦詩、山口寛二、伊藤義人
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15H06547
[Presentation] p62, a Key Regulator for Initiation and Development of HCC2015
- Author(s)
  Atsushi Umemura, Yoshito Itoh, Maria T. Diaz-Meco, Jorge Moscat, and Michael Karin
- Organizer
  AASLD Liver meeting 2015
- Place of Presentation
  Moscone Center in San Francisco
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06547

1. Minami Masahito

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
2. 安居幸一郎

# of Collaborated Projects : 0results

# of Collaborated Products : 4results
3. 小西英幸

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
4. 森正樹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
5. 田中真二

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

Umemura Atsushi 楳村 敦詩

Research Projects

Research Products

Co-Researchers

The role of p62 in the HCC initiation and progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatic nucleotide binding oligomerization domain-like receptors pyrin domain-containing 3 inflammasomes are associated with the histologic severity of non-alcoholic fatty liver disease.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of hepatocellular carcinoma in Japanese patients with biopsy-proven non-alcoholic fatty liver disease: Association between PNPLA3 genotype and hepatocarcinogenesis/fibrosis progression.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current status and future prospects of chemotherapy for advanced hepatocellular carcinoma.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肝細胞癌とオートファジー2016

Author(s)

Journal Title

Data Source

[Journal Article] NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genome-wide DNA methylation analysis in hepatocellular carcinoma.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] The Effect of mTORC1 Inhibition on NAFLD and subsequent HCC Development2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 肝発癌・進展における，mTORC1およびp62-Nrf2シグナルの役割2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 肝癌および慢性肝疾患の病態におけるmTORC1阻害の影響2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] p62, a Key Regulator for Initiation and Development of HCC2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Umemura Atsushi 楳村敦詩