ARAI JUN 荒井潤

… Alternative Names

Jun Arai 荒井潤

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Researcher Number	30766176
Other IDs
Affiliation (Current)	2022: 昭和大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020: 昭和大学, 医学部, 講師 2019: 昭和大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator MICA / NK細胞 / 肝細胞癌 / 癌免疫 / ロイコトリエン拮抗薬 / レチノイド / ADAM9 / レゴラフェニブ / 癌免疫療法 Except Principal Investigator 肝細胞癌 … More / MICA / 大規模化合物ライブラリ / シェダーゼ阻害薬 / 肝癌 / 自然免疫 / 腫瘍 / NK細胞 Less

肝癌感受性遺伝子MICAのシェダーゼ阻害を基盤とした新規治療薬の探索
- Principal Investigator
  
  太和田暁之
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Chiba University
Development of anticancer therapy targeting ADAM9 and NK cells in HCCPrincipal Investigator
- Principal Investigator
  
  Jun Arai
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Showa University

All 2021 2020 2019

All Journal Article Presentation

[Journal Article] Leukotriene receptor antagonists enhance HCC treatment efficacy by inhibiting ADAMs and suppressing MICA shedding2021
- Author(s)
  Arai J, Goto K, Otoyama Y, Nakajima Y, Sugiura I, Kajiwara A, Tojo M, Ichikawa Y, Uozumi S, Shimozuma Y, Uchikoshi M, Sakaki M, Nozawa H, Nakagawa R, Muroyama R, Kato N, Yoshida H.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 70 Pages: 203-213
- DOI
  10.1007/s00262-020-02660-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03633, KAKENHI-PROJECT-18K07996, KAKENHI-PROJECT-19K16723
[Journal Article] Decreased expression of interferon‐stimulated genes in B cells of patients with chronic hepatitis C during interferon‐free therapy potentially suggests the eradication of hepatitis C virus in the B cells: A cohort study2020
- Author(s)
  Arai Jun、Ito Takayoshi、Shimozuma Yuu、Uchikoshi Manabu、Nakajima Yoko、Sakaki Masashi、Uozumi Shojiro、Kajiwara Atsushi、Sugiura Ikuya、Otoyama Yumi、Nozawa Hisako、Kurihara Toshikazu、Eguchi Junichi、Nomura Norihiro、Sakuma Dai、Sato Masashi、Deguchi Yoshio、Yoshida Hitoshi
- Journal Title
  
  Health Science Reports
  
  Volume: 3 Pages: 1-10
- DOI
  10.1002/hsr2.176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16723
[Journal Article] Laparoscopic Treatment of a Hepatoduodenal Ligament Schwannoma With Infrared Indocyanine Green Fluorescence2020
- Author(s)
  Tomioka K, Aoki T, Koizumi T, Elewa A, Kusano T, Matsuda K, Nogaki K, Tashiro Y, Wada Y, Hakozaki T, Shibata H, Hirai T, Yamazaki T, Saito K, Enami Y, Sugiura I, Nakajima Y, Arai J, Kajiwara A, Uozumi S, Shimozuma YU, Uchikoshi M, Sakaki M, Yoshida H, Miura S, Murakami M
- Journal Title
  
  In Vivo
  
  Volume: 34 Pages: 2037-2041
- DOI
  10.21873/invivo.12004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08658, KAKENHI-PROJECT-19K12848, KAKENHI-PROJECT-19K16723
[Journal Article] Three cases of histologically proven hepatic epithelioid hemangioendothelioma evaluated using a second-generation microbubble contrast medium in ultrasonography: case reports2019
- Author(s)
  Jun Arai, Yuu Shimozuma, Yumi Otoyama, Ikuya Sugiura, Yoko Nakajima, et al
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 19 Pages: 187-194
- DOI
  10.1186/s12876-019-1113-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16723
[Presentation] レチノイン酸による肝発癌感受性分子MICAの制御効果2020
- Author(s)
  音山裕美,荒井潤,杉浦育也,中島陽子,梶原敦,市川雪,魚住祥二郎,下間祐,打越学,坂木理,後藤覚,中川良,室山良介,加藤直也,吉田仁
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K16723
[Presentation] 肝発癌感受性分子MICAの切断阻害を目的としたADAM9酵素活性抑制薬の探索2020
- Author(s)
  音山裕美,荒井潤,吉田仁
- Organizer
  第43回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-19K16723
[Presentation] レゴラフェニブ治療が大腸癌に与えるNK細胞活性化シグナルへの影響2020
- Author(s)
  荒井潤,後藤覚,音山裕美,杉浦育也,中島陽子,梶原敦,市川雪,魚住祥二郎,下間祐,打越学,坂木理,中川良,室山良介,加藤直也,吉田仁
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K16723
[Presentation] ADAM9酵素活性阻害によるMICA-NK axisを標的とした肝癌治療戦略2020
- Author(s)
  荒井潤,後藤覚,音山裕美,杉浦育也,中島陽子,梶原敦,市川雪,魚住祥二郎,下間祐,打越学,坂木理,中川良,室山良介,加藤直也,吉田仁
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K16723

1. 太和田暁之 (10596159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 室山良介 (50549459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. MURAKAMI Masahiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 加藤直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 青木武士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 田代良彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 榎並延太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ARAI JUN 荒井 潤

Jun Arai 荒井 潤

Research Projects

Research Products

Co-Researchers

肝癌感受性遺伝子MICAのシェダーゼ阻害を基盤とした新規治療薬の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of anticancer therapy targeting ADAM9 and NK cells in HCCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Leukotriene receptor antagonists enhance HCC treatment efficacy by inhibiting ADAMs and suppressing MICA shedding2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased expression of interferon‐stimulated genes in B cells of patients with chronic hepatitis C during interferon‐free therapy potentially suggests the eradication of hepatitis C virus in the B cells: A cohort study2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Laparoscopic Treatment of a Hepatoduodenal Ligament Schwannoma With Infrared Indocyanine Green Fluorescence2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three cases of histologically proven hepatic epithelioid hemangioendothelioma evaluated using a second-generation microbubble contrast medium in ultrasonography: case reports2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] レチノイン酸による肝発癌感受性分子MICAの制御効果2020

Author(s)

Organizer

Data Source

[Presentation] 肝発癌感受性分子MICAの切断阻害を目的としたADAM9酵素活性抑制薬の探索2020

Author(s)

Organizer

Data Source

[Presentation] レゴラフェニブ治療が大腸癌に与えるNK細胞活性化シグナルへの影響2020

Author(s)

Organizer

Data Source

[Presentation] ADAM9酵素活性阻害によるMICA-NK axisを標的とした肝癌治療戦略2020

Author(s)

Organizer

Data Source

ARAI JUN 荒井潤

Jun Arai 荒井潤