Saito Takeo 齋藤竹生

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saito takeo 齋藤竹生

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Researcher Number	30767611
Affiliation (Current)	2025: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 藤田医科大学, 医学部, 講師 2018 – 2019: 藤田医科大学, 医学部, 講師 2016 – 2017: 藤田保健衛生大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science Except Principal Investigator Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator ファーマコゲノミクス / 薬物血中濃度 / ゲノム / 抗うつ薬 / 抗精神病薬 / 精神科 / バイオマーカー / 顆粒球減少症 / 無顆粒球症 / クロザピン … More / 薬理ゲノム学 / 双極性障害 / 精神薬理遺伝学 / 精神神経科学 / 薬理遺伝学 / ラモトリギン … More Except Principal Investigator 統合失調症 / 双極症 Less

Development of a diagnostic and symptom classification method for mental disorders using polygenic scores
- Principal Investigator
  
  池田匡志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nagoya University
抗うつ薬の遺伝子多型情報を基盤とする用量個別化設定を目指した薬理ゲノム学研究Principal Investigator
- Principal Investigator
  
  齋藤竹生
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Fujita Health University
Pharmacogenomic study for optimizing dosage of antipsychotic drugs based on individual genetic polymorphismPrincipal Investigator
- Principal Investigator
  
  Saito Takeo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Fujita Health University
Investigation of the pathogenic mechanisms of clozapine-induced agranulocytosisPrincipal Investigator
- Principal Investigator
  
  Takeo Saito
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Fujita Health University
Pharmacogenomic study of lamotriginePrincipal Investigator
- Principal Investigator
  
  saito takeo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Fujita Health University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice2023
- Author(s)
  Yamamoto Hirona、Lee-Okada Hyeon-Cheol、Ikeda Masashi、Nakamura Takumi、Saito Takeo、Takata Atsushi、Yokomizo Takehiko、Iwata Nakao、Kato Tadafumi、Kasahara Takaoki
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 28 Issue: 7 Pages: 2848-2856
- DOI
  10.1038/s41380-023-01988-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-21K07490, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-23K24264, KAKENHI-PLANNED-20H05777
[Journal Article] Differential genetic correlations across major psychiatric disorders between Eastern and Western countries2023
- Author(s)
  Saito Takeo、Ikeda Masashi、Terao Chikashi、Ashizawa Takuma、Miyata Masami、Tanaka Satoshi、Kanazawa Tetsufumi、Kato Tadafumi、Kishi Taro、Iwata Nakao
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 77 Issue: 2 Pages: 118-119
- DOI
  10.1111/pcn.13498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07490, KAKENHI-PROJECT-21H02854
[Journal Article] Pharmacogenomic-guided clozapine administration based on HLA-DQB1, HLA-B and SLCO1B3-SLCO1B7 variants: an effectiveness and cost-effectiveness analysis2022
- Author(s)
  Ninomiya Kohei、Saito Takeo、Ikeda Masashi、Iwata Nakao、Girardin Fran?ois R.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13
- DOI
  10.3389/fphar.2022.1016669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07490
[Journal Article] Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multi‐population datasets2022
- Author(s)
  Aoki Rei、Saito Takeo、Ninomiya Kohei、Shimasaki Ayu、Ashizawa Takuma、Ito Kenta、Ikeda Masashi、Iwata Nakao
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: - Issue: 8 Pages: 361-366
- DOI
  10.1111/pcn.13372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07490, KAKENHI-PROJECT-21H02854
[Journal Article] Proportion of subjects with psychotic features in bipolar disorder correlated with treatment response by antipsychotics for acute mania2022
- Author(s)
  Ikeda Masashi、Saito Takeo、Kanazawa Tetsufumi、Kishi Taro、Iwata Nakao
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 76 Issue: 11 Pages: 596-598
- DOI
  10.1111/pcn.13460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07490, KAKENHI-PROJECT-21H02854
[Journal Article] Cost effectiveness of pharmacogenetic-guided clozapine administration based on risk of HLA variants in Japan and the UK2021
- Author(s)
  Ninomiya Kohei、Saito Takeo、Okochi Tomo、Taniguchi Satoru、Shimasaki Ayu、Aoki Rei、Hata Takeo、Mushiroda Taisei、Kanazawa Tetsufumi、Ikeda Masashi、Iwata Nakao
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11 Issue: 1 Pages: 362-362
- DOI
  10.1038/s41398-021-01487-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07490, KAKENHI-PROJECT-21H02854
[Journal Article] Human leukocyte antigen DRB1*04:05 and clozapine-induced agranulocytosis/granulocytopenia2020
- Author(s)
  Saito Takeo、Ikeda Masashi、Mushiroda Taisei、Iwata Nakao、Clozapine Pharmacogenomics Consortium of Japan (CPC-J)
- Journal Title
  
  Australian & New Zealand Journal of Psychiatry
  
  Volume: 54(5) Issue: 5 Pages: 545-546
- DOI
  10.1177/0004867419900296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04251, KAKENHI-PROJECT-18K15497, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18KT0022
[Journal Article] Global DNA hypomethylation and its correlation to the betaine level in peripheral blood of patients with schizophrenia2020
- Author(s)
  Murata Y, Ikegame T, Koike S, Saito T, Ikeda M, Sasaki T, Iwata N, Kasai K, Bundo M, Iwamoto K
- Journal Title
  
  Progress in Neuropsychopharmacology & Biological Psychiatry
  
  Volume: 99 Pages: 109855-109855
- DOI
  10.1016/j.pnpbp.2019.109855
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15520, KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-18H05430, KAKENHI-PROJECT-18H02753, KAKENHI-PROJECT-20KK0193, KAKENHI-PROJECT-18K15497, KAKENHI-PLANNED-16H06399
[Journal Article] Polygenic risk scores in schizophrenia with clinically significant copy number variants2019
- Author(s)
  Taniguchi Satoru、Ninomiya Kohei、Kushima Itaru、Saito Takeo、Shimasaki Ayu、Sakusabe Takaya、Momozawa Yukihide、Kubo Michiaki、Kamatani Yoichiro、Ozaki Norio、Ikeda Masashi、Iwata Nakao
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 74 Issue: 1 Pages: 35-39
- DOI
  10.1111/pcn.12926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04251, KAKENHI-PROJECT-18K15497
[Journal Article] Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect2018
- Author(s)
  Ikeda M,Takahashi A,Kamatani Y,Momozawa Y,Saito T,Kondo K,Shimasaki A,Kawase K,Sakusabe T,Iwayama Y,Toyota T,Wakuda T,Kikuchi M,Kanahara N,Yamamori H,Yasuda Y,Watanabe Y,Hoya S,Aleksic B,Kushima I,Arai H,Takaki M,Hattori K,Kunugi H,Okahisa Y,Ohnuma T,Ozaki N,Someya T,Hashimoto R,Yoshikawa T,Kubo M,Iwata N
- Journal Title
  
  Schizophrenia Bulletin
  
  Volume: 印刷中 Issue: 4 Pages: 824-834
- DOI
  10.1093/schbul/sby140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15497, KAKENHI-PROJECT-16H05378, KAKENHI-PROJECT-17H04251, KAKENHI-PROJECT-15K09806, KAKENHI-PROJECT-16K10186, KAKENHI-PROJECT-16K10188, KAKENHI-PROJECT-26293261, KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-18K07601, KAKENHI-PROJECT-19K08019, KAKENHI-PROJECT-19K08067, KAKENHI-PROJECT-19K08070, KAKENHI-PROJECT-19H05467
[Journal Article] Re-evaluating classical body type theories: genetic correlation between psychiatric disorders and body mass index2018
- Author(s)
  Ikeda Masashi、Tanaka Satoshi、Saito Takeo、Ozaki Norio、Kamatani Yoichiro、Iwata Nakao
- Journal Title
  
  Psychological Medicine
  
  Volume: in press Issue: 10 Pages: 1-4
- DOI
  10.1017/s0033291718000685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05378, KAKENHI-PROJECT-17H04251, KAKENHI-PROJECT-16K19785
[Journal Article] Transethnic Replication Study to Assess the Association Between Clozapine-Induced Agranulocytosis/Granulocytopenia and Genes at 12p12.2 in a Japanese Population2017
- Author(s)
  Saito T, Ikeda M, Hashimoto R, Iwata N; Members of the Clozapine Pharmacogenomics Consortium of Japan
- Journal Title
  
  Biol Psychiatry
  
  Volume: in press Issue: 1 Pages: e9-e10
- DOI
  10.1016/j.biopsych.2016.12.009
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05378, KAKENHI-PROJECT-16K19785, KAKENHI-PROJECT-16K10188, KAKENHI-PROJECT-26293266, KAKENHI-PROJECT-16H05375
[Presentation] Differential genetic correlations across major psychiatric disorders between Eastern and Western countries2023
- Author(s)
  齋藤竹生
- Organizer
  Congress of Psychiatric Genetics 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07490
[Presentation] 向精神薬の薬理ゲノム学2023
- Author(s)
  齋藤竹生
- Organizer
  第33回日本臨床精神神経薬理学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07490
[Presentation] 精神疾患のゲノム研究の現在と展望2023
- Author(s)
  齋藤竹生
- Organizer
  第45回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-21K07490
[Presentation] クロザピン治療における薬理ゲノム学研究の応用と治療抵抗性統合失調症の遺伝子研究2023
- Author(s)
  齋藤竹生
- Organizer
  第119回日本精神神経学会学術総会,
- Data Source
  KAKENHI-PROJECT-21K07490
[Presentation] 向精神薬の薬理ゲノム学2021
- Author(s)
  齋藤竹生
- Organizer
  第43回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-21K07490
[Presentation] 精神科遺伝学がもたらした地平薬理遺伝学による臨床現場への応用を見据えて2019
- Author(s)
  齋藤竹生
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15497
[Presentation] 生物学的精神医学のフロンティア精神疾患の薬理ゲノム学2019
- Author(s)
  齋藤竹生
- Organizer
  第115回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15497
[Presentation] 向精神薬の薬理ゲノム学研究（第7回若手研究者育成プログラム）2018
- Author(s)
  齋藤竹生
- Organizer
  第40回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15497
[Presentation] 精神疾患の薬理遺伝・ゲノム学（シンポジウム23）2017
- Author(s)
  齋藤竹生
- Organizer
  第39回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K19785
[Presentation] 精神科臨床医として医学研究に取り組む意義(精神医学研究推進のための人材育成シンポジウム21)2017
- Author(s)
  齋藤竹生
- Organizer
  第113回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19785
[Presentation] 向精神薬の薬理ゲノム学研究（若手研究者育成プログラム最優秀奨励賞選考発表会）2017
- Author(s)
  齋藤竹生
- Organizer
  第39回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16K19785
[Presentation] 向精神薬の薬理ゲノム学的研究：クロザピンの薬理ゲノム学的研究2016
- Author(s)
  齋藤竹生
- Organizer
  日本生物学的精神医学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-16K19785

1. Ikeda Masashi (60424933)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. MURATA Yui

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 岩田仲生

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 高田篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saito Takeo 齋藤 竹生

saito takeo 齋藤 竹生

Research Projects

Research Products

Co-Researchers

Development of a diagnostic and symptom classification method for mental disorders using polygenic scores

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

抗うつ薬の遺伝子多型情報を基盤とする用量個別化設定を目指した薬理ゲノム学研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pharmacogenomic study for optimizing dosage of antipsychotic drugs based on individual genetic polymorphismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the pathogenic mechanisms of clozapine-induced agranulocytosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pharmacogenomic study of lamotriginePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential genetic correlations across major psychiatric disorders between Eastern and Western countries2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacogenomic-guided clozapine administration based on HLA-DQB1, HLA-B and SLCO1B3-SLCO1B7 variants: an effectiveness and cost-effectiveness analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multi‐population datasets2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proportion of subjects with psychotic features in bipolar disorder correlated with treatment response by antipsychotics for acute mania2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cost effectiveness of pharmacogenetic-guided clozapine administration based on risk of HLA variants in Japan and the UK2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human leukocyte antigen DRB1*04:05 and clozapine-induced agranulocytosis/granulocytopenia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global DNA hypomethylation and its correlation to the betaine level in peripheral blood of patients with schizophrenia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polygenic risk scores in schizophrenia with clinically significant copy number variants2019

Author(s)

Journal Title

DOI

Data Source

Saito Takeo 齋藤竹生

saito takeo 齋藤竹生

[Presentation] 精神科遺伝学がもたらした地平薬理遺伝学による臨床現場への応用を見据えて2019

[Presentation] 生物学的精神医学のフロンティア精神疾患の薬理ゲノム学2019