Kubota Akatsuki 久保田暁

Researcher Number	30771589
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 講師 2022 – 2023: 東京大学, 医学部附属病院, 講師 2018 – 2021: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 52020:Neurology-related / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator 炎症 / コレステロール代謝 / 特発性炎症性筋疾患 / 連鎖解析 / 遺伝子 / 封入体筋炎 Except Principal Investigator 筋炎 / サルコペニア / 凍結標本 / 頭頚部外科手術 … More / 嚥下筋 / 筋病理 / 分子病理 / 臨床病理像 / 特異抗体陰性 / 膠原病関連自己抗体 / 免疫介在性壊死性ミオパチー / 免疫組織化学 / 臨床像 / 全身性強皮症 / 筋炎特異抗体 / 炎症性筋疾患 / 重症筋無力症 / irAE / RNA-シークエンス解析 / PD-L1 / PD-1 / 免疫チェックポイント / 多発筋炎 / 封入体筋炎 / 発現解析 / マクロファージ / 免疫チェックポイント分子 Less

Association between cholesterol metabolism and inflammation in idiopathic inflammatory myopathiesPrincipal Investigator
- Principal Investigator
  
  久保田暁
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  The University of Tokyo
ヒト嚥下筋の組織学的検討―多施設共同研究によるサルコペニアの嚥下障害の病態解明
- Principal Investigator
  
  巨島文子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Aichi Medical University
筋炎特異抗体“陰性”筋炎の臨床・分子病理像解析と合併背景免疫の病態への関与の検討
- Principal Investigator
  
  清水潤
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tokyo University of Technology
Role of immune checkpoint molecules and macrophages in inflammatory myopathies
- Principal Investigator
  
  SHIMIZU Jun
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tokyo University of Technology
Molecular genetic analysis of familial inclusion body myositisPrincipal Investigator
- Principal Investigator
  
  Kubota Akatsuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Alanine transaminase is predominantly increased in the active phase of anti-HMGCR myopathy2022
- Author(s)
  Akatsuki Kubota, Jun Shimizu, Atsushi Unuma, Meiko Maeda, Yuichiro Shirota, Masato Kadoya, Naohiro Uchio, Yoshio Sakiyama, Noritoshi Arai, Yasushi Shiio, Yoshikazu Uesaka, Hideji Hashida, Nobue K Iwata, Jun Goto, Ran Nakashima, Tsuneyo Mimori, Tatsushi Toda
- Journal Title
  
  Neuromuscular Disorders
  
  Volume: 32(1) Issue: 1 Pages: 25-32
- DOI
  10.1016/j.nmd.2021.10.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15440, KAKENHI-PROJECT-18K07542, KAKENHI-PROJECT-20H00526
[Journal Article] DMD exon 2 duplication due to a complex genomic rearrangement is associated with a somatic mosaicism2022
- Author(s)
  Akatsuki Kubota, Hiroyuki Ishiura, Kristine Joyce Linay Porto, Masaki Tanaka, Jun Mitsui, Atsushi Unuma, Hisataka Maki, Issei Komuro, Shoji Tsuji, Jun Shimizu, Tatsushi Toda
- Journal Title
  
  Neuromuscular Disorders
  
  Volume: 32(3) Issue: 3 Pages: 263-269
- DOI
  10.1016/j.nmd.2021.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15440, KAKENHI-PROJECT-20H03588, KAKENHI-PROJECT-20H00526
[Journal Article] Pembrolizumab on pre-existing inclusion body myositis: a case report2020
- Author(s)
  Uchio Naohiro、Unuma Atsushi、Kakumoto Toshiyuki、Osaki Masao、Zenke Yoshitaka、Sakuta Kenichi、Kubota Akatsuki、Uesaka Yoshikazu、Toda Tatsushi、Shimizu Jun
- Journal Title
  
  BMC Rheumatology
  
  Volume: 4 Issue: 1 Pages: 48-48
- DOI
  10.1186/s41927-020-00144-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07956, KAKENHI-PROJECT-20H00526
[Presentation] 合併抗体存在時に特異的筋病理像が影響を受けるか？2023
- Author(s)
  北村明日香，清水潤，前田明子。久保田暁，戸田達史
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07506
[Presentation] 全身性強皮症の筋病理所見の特徴と出現自己抗体2023
- Author(s)
  北村明日香，清水潤，久保田暁，前田明子，住田隼一，伏田奈津美，松下貴史，浅野善英，戸田達史
- Organizer
  第64回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-22K07506
[Presentation] 全身性強皮症における筋障害の臨床的位置付けに関する観察検討2023
- Author(s)
  北村明日香，清水潤，久保田暁，小巻奨吾，前田明子，住田隼一，伏田奈津美，松下貴史，浅野善英，戸田達史
- Organizer
  第9回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07506
[Presentation] HMGCRミオパチーではALTが優位に上昇する2022
- Author(s)
  久保田暁、清水潤、鵜沼敦、前田明子、代田悠一郎、角谷真人、中嶋蘭、三森経世、戸田達史
- Organizer
  第63回日本神経学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15440
[Presentation] 筋炎における筋内鞘血管MxA(myxovirus resistance protein A)の染色性の意義に関する検討2022
- Author(s)
  北村明日香，清水潤，前田明子。久保田暁，戸田達史
- Organizer
  第34回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07506
[Presentation] Application of droplet digital PCR for detection of somatic mosaicism in dystrophinopathy.2021
- Author(s)
  Akatsuki Kubota, Hiroyuki Ishiura, Kristine Joyce Linay Porto, Masaki Tanaka, Atsushi Unuma, Shoji Tsuji, Jun Shimizu, Tatsushi Toda
- Organizer
  第62回日本神経学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15440
[Presentation] Clinical description of familial inclusion body myositis and molecular genetic analysis.2019
- Author(s)
  Akatsuki Kubota, Hiroyuki Ishiura, Jun Mitsui, Jun Shimizu, Shoji Tsuji, Tatsushi Toda
- Organizer
  3rd Global Conference on Myositis 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15440

1. SHIMIZU Jun (40260492)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. 石浦浩之 (40632849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 巨島文子 (70972785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 藤本保志 (40344337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 杉山庸一郎 (50629566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 國枝顕二郎 (50701885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 平野愛 (60596097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 森健一 (80823666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 椋代茂之 (00821860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 前田明子 (20646799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kubota Akatsuki 久保田 暁

Research Projects

Research Products

Co-Researchers

Association between cholesterol metabolism and inflammation in idiopathic inflammatory myopathiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト嚥下筋の組織学的検討―多施設共同研究によるサルコペニアの嚥下障害の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

筋炎特異抗体“陰性”筋炎の臨床・分子病理像解析と合併背景免疫の病態への関与の検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of immune checkpoint molecules and macrophages in inflammatory myopathies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular genetic analysis of familial inclusion body myositisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Alanine transaminase is predominantly increased in the active phase of anti-HMGCR myopathy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DMD exon 2 duplication due to a complex genomic rearrangement is associated with a somatic mosaicism2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pembrolizumab on pre-existing inclusion body myositis: a case report2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 合併抗体存在時に特異的筋病理像が影響を受けるか？2023

Author(s)

Organizer

Data Source

[Presentation] 全身性強皮症の筋病理所見の特徴と出現自己抗体2023

Author(s)

Organizer

Data Source

[Presentation] 全身性強皮症における筋障害の臨床的位置付けに関する観察検討2023

Author(s)

Organizer

Data Source

[Presentation] HMGCRミオパチーではALTが優位に上昇する2022

Author(s)

Organizer

Data Source

[Presentation] 筋炎における筋内鞘血管MxA(myxovirus resistance protein A)の染色性の意義に関する検討2022

Author(s)

Organizer

Data Source

[Presentation] Application of droplet digital PCR for detection of somatic mosaicism in dystrophinopathy.2021

Author(s)

Organizer

Data Source

[Presentation] Clinical description of familial inclusion body myositis and molecular genetic analysis.2019

Author(s)

Organizer

Data Source

Kubota Akatsuki 久保田暁