Taniguchi Atsuhiko 谷口敦彦

Researcher Number	30790125
Other IDs
Affiliation (Current)	2025: 東京薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京薬科大学, 薬学部, 准教授 2017 – 2018: 東京薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Biomolecular chemistry Except Principal Investigator Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords	Principal Investigator 光酸素化 / マイオスタチン / ペプチド / タンパク質不活化 / Sタンパク質 / 3CLプロテアーゼ / ウイルス / 創薬化学 / タンパク質間相互作用 / 生体分子の化学修飾 / 触媒 … More Except Principal Investigator … More ケミカルバイオロジー / 創薬 / ペプチドー薬物架橋体 / 抗ウイルス剤 / プロテアーゼ阻害剤 / ジストログリカン / 有機合成化学 / 糖鎖 / 抗体医療 / 筋ジストロフィー Less

ラミニン結合性機能糖鎖を応用した筋ジストロフィーに対する創薬研究
- Principal Investigator
  
  遠藤玉夫
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of innovative drug discovery based on SARS-CoV-2 3CL protease inhibitor YH-53
- Principal Investigator
  
  林良雄
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
選択的光酸素化を基盤とした汎用的タンパク質不活化法~新規抗ウイルス戦略への展開~Principal Investigator
- Principal Investigator
  
  谷口敦彦
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Inhibition of protein interaction with selective photooxygenationPrincipal Investigator
- Principal Investigator
  
  Taniguchi Atsuhiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Control of TGF-beta related protein based on selective photooxygenationPrincipal Investigator
- Principal Investigator
  
  Taniguchi Atsuhiko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Establishment of One-Pot Disulfide-Driven Cyclic Peptide Synthesis with a 3-Nitro-2-pyridinesulfenate2023
- Author(s)
  Shida, H., Taguchi, A., Konno, S., Takayama, K., Taniguchi, A., Hayashi, Y.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 71 Issue: 6 Pages: 435-440
- DOI
  10.1248/cpb.c23-00087
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2023-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27305
[Journal Article] Development of Myostatin Inhibitory d-Peptides to Enhance the Potency, Increasing Skeletal Muscle Mass in Mice2022
- Author(s)
  Takayama Kentaro、Hitachi Keisuke、Okamoto Hideyuki、Saitoh Mariko、Odagiri Miki、Ohfusa Rina、Shimada Takahiro、Taguchi Akihiro、Taniguchi Atsuhiko、Tsuchida Kunihiro、Hayashi Yoshio
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 13 Issue: 3 Pages: 492-498
- DOI
  10.1021/acsmedchemlett.1c00705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-20K07315
[Journal Article] Strategic structure-activity relationship study on a follistatin-derived myostatin inhibitory peptide2021
- Author(s)
  Saitoh Mariko、Takayama Kentaro、Roppongi Yoshimi、Shimada Takahiro、Taguchi Akihiro、Taniguchi Atsuhiko、Hayashi Yoshio
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 46 Pages: 128163-128163
- DOI
  10.1016/j.bmcl.2021.128163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001
[Journal Article] Synthesis and biological evaluation of a monocyclic Fc-binding antibody-recruiting molecule for cancer immunotherapy2021
- Author(s)
  Sasaki Koichi、Muguruma Kyohei、Osawa Rento、Fukuda Akane、Taniguchi Atsuhiko、Kishimura Akihiro、Hayashi Yoshio、Mori Takeshi、Katayama Yoshiki
- Journal Title
  
  RSC Medicinal Chemistry
  
  Volume: 12 Issue: 3 Pages: 406-409
- DOI
  10.1039/d0md00337a
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-21K19055
[Journal Article] Proposal for the binding mode of the 23-mer inhibitory peptide to myostatin2021
- Author(s)
  Asari Tomo、Ikeyama Hiroaki、Taguchi Akihiro、Taniguchi Atsuhiko、Hayashi Yoshio、Takayama Kentaro
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 40 Pages: 116181-116181
- DOI
  10.1016/j.bmc.2021.116181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03356
[Journal Article] Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation2021
- Author(s)
  Okamoto Hideyuki、Taniguchi Atsuhiko、Usami Shoya、Katsuyama Masahiro、Konno Sho、Taguchi Akihiro、Takayama Kentaro、Hayashi Yoshio
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 19 Issue: 1 Pages: 199-207
- DOI
  10.1039/d0ob02042g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03356
[Journal Article] Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application2021
- Author(s)
  Kobayakawa Takuya、Azuma Chika、Watanabe Yuki、Sawamura Shunsuke、Taniguchi Atsuhiko、Hayashi Yoshio、Tsuji Kohei、Tamamura Hirokazu
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 7 Pages: 5091-5101
- DOI
  10.1021/acs.joc.0c03019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K16312, KAKENHI-PROJECT-20H03362
[Journal Article] “On‐Resin” Disulfide Peptide Synthesis with Methyl 3‐Nitro‐2‐pyridinesulfenate2021
- Author(s)
  Kobayashi Kiyotaka、Taguchi Akihiro、Cui Yan、Shida Hayate、Muguruma Kyohei、Takayama Kentaro、Taniguchi Atsuhiko、Hayashi Yoshio
- Journal Title
  
  European Journal of Organic Chemistry
  
  Volume: 2021 Issue: 6 Pages: 956-963
- DOI
  10.1002/ejoc.202001517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K16324, KAKENHI-PROJECT-19H03356
[Journal Article] Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in the brains of Alzheimer’s disease model mice2021
- Author(s)
  Ozawa S, Hori Y, Shimizu Y, Taniguchi A, Suzuki T, Wang W, Chiu YW, Koike R, Yokoshima S, Fukuyama T, Takatori S, Sohma Y, Kanai M, Tomita T
- Journal Title
  
  Brain
  
  Volume: - Issue: 6 Pages: 1884-1897
- DOI
  10.1093/brain/awab058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06653, KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K07080, KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-20H00489
[Journal Article] Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis2021
- Author(s)
  Uchiyama Chihiro、Fukuda Akane、Mukaiyama Minagi、Nakazawa Yoshiki、Kuramochi Yuka、Muguruma Kyohei、Arimoto Mitsue、Ninomiya Akihiro、Kako Koichiro、Katsuyama Yohei、Konno Sho、Taguchi Akihiro、Takayama Kentaro、Taniguchi Atsuhiko、Nagumo Yoko、Usui Takeo、Hayashi Yoshio
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 60 Issue: 16 Pages: 8792-8797
- DOI
  10.1002/anie.202015193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H02893, KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-17K01942
[Journal Article] Design and synthesis of peptidic partial agonists of human neuromedin U receptor 1 with enhanced serum stability2020
- Author(s)
  Takayama Kentaro、Mori Kenji、Asari Tomo、Sohma Yuko、Nomura Erina、Sasaki Yu、Taguchi Akihiro、Taniguchi Atsuhiko、Miyazato Mikiya、Minamino Naoto、Kangawa Kenji、Hayashi Yoshio
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 18 Pages: 127436-127436
- DOI
  10.1016/j.bmcl.2020.127436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-18K08497
[Journal Article] Discovery of a follistatin-derived myostatin inhibitory peptide2020
- Author(s)
  Saitoh Mariko、Takayama Kentaro、Hitachi Keisuke、Taguchi Akihiro、Taniguchi Atsuhiko、Tsuchida Kunihiro、Hayashi Yoshio
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 3 Pages: 126892-126892
- DOI
  10.1016/j.bmcl.2019.126892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-17K08646, KAKENHI-PROJECT-17K15484
[Journal Article] Disulfide-driven cyclic peptide synthesis of human endothelin-2 with a solid-supported Npys-Cl2020
- Author(s)
  Akihiro Taguchi, Kiyotaka Kobayashi, Yan Cui, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Journal Title
  
  J. Org. Chem.
  
  Volume: 85 Issue: 3 Pages: 1495-1503
- DOI
  10.1021/acs.joc.9b02362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-19K07001
[Journal Article] A chemically stable peptide agonist to neuromedin U receptor type 22020
- Author(s)
  Takayama Kentaro、Mori Kenji、Tanaka Akiko、Sasaki Yu、Sohma Yuko、Taguchi Akihiro、Taniguchi Atsuhiko、Sakane Toshiyasu、Yamamoto Akira、Miyazato Mikiya、Minamino Naoto、Kangawa Kenji、Hayashi Yoshio
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 10 Pages: 115454-115454
- DOI
  10.1016/j.bmc.2020.115454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-18K08497
[Journal Article] Use of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate in the construction of disulfide-linked hybrid molecules2020
- Author(s)
  Cui Yan、Taguchi Akihiro、Kobayashi Kiyotaka、Shida Hayate、Takayama Kentaro、Taniguchi Atsuhiko、Hayashi Yoshio
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 18 Issue: 36 Pages: 7094-7097
- DOI
  10.1039/d0ob01370f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K16324, KAKENHI-PROJECT-19H03356
[Journal Article] Enzymatic stability of myostatin inhibitory 16-mer peptides2020
- Author(s)
  Takayama, Kentaro; Odagiri, Miki; Taguchi, Akihiro; Taniguchi, Atsuhiko; Hayashi, Yoshio
- Journal Title
  
  Chemical & Pharmaceutical Bulletin
  
  Volume: 6 Pages: 512-515
- NAID
  130007850052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001
[Journal Article] Photo-oxygenation inhibits tau amyloid formation2019
- Author(s)
  Suzuki T*, Hori Y*, Sawazaki T, Shimizu Y, Nemoto Y, Taniguchi A, Ozawa S, Sohma Y, Kanai M, Tomita T
- Journal Title
  
  Chem. Commun.
  
  Volume: 55(44) Issue: 44 Pages: 6165-6168
- DOI
  10.1039/c9cc01728c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06653, KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K22484, KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-19J14873, KAKENHI-PROJECT-19J23179, KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-17H01522, KAKENHI-PROJECT-16H06216
[Journal Article] Design and synthesis of potent myostatin inhibitory cyclic peptides2019
- Author(s)
  Rentier Cedric、Takayama Kentaro、Saitoh Mariko、Nakamura Akari、Ikeyama Hiroaki、Taguchi Akihiro、Taniguchi Atsuhiko、Hayashi Yoshio
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 7 Pages: 1437-1443
- DOI
  10.1016/j.bmc.2019.02.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04658, KAKENHI-PROJECT-19K07001
[Journal Article] Inactivation of myostatin by photo-oxygenation using catalyst-functionalized peptides2019
- Author(s)
  Okamoto Hideyuki、Taniguchi Atsuhiko、Usami Shoya、Taguchi Akihiro、Takayama Kentaro、Hayashi Yoshio
- Journal Title
  
  Chemical Communications
  
  Volume: 55 Issue: 62 Pages: 9108-9111
- DOI
  10.1039/c9cc04368c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001
[Journal Article] Photophysical properties and application in live cell imaging of B,B-fluoro-perfluoroalkyl BODIPYs2019
- Author(s)
  Taniguchi Atsuhiko、Sawazaki Taka、Shimizu Yusuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  MedChemComm
  
  Volume: 印刷中 Issue: 7 Pages: 1121-1125
- DOI
  10.1039/c9md00011a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13260, KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-16H06216, KAKENHI-PROJECT-17H01522
[Journal Article] Chain-Shortened Myostatin Inhibitory Peptides Improve Grip Strength in Mice2019
- Author(s)
  Takayama Kentaro、Asari Tomo、Saitoh Mariko、Nirasawa Kei、Sasaki Eri、Roppongi Yoshimi、Nakamura Akari、Saga Yusuke、Shimada Takahiro、Ikeyama Hiroaki、Taguchi Akihiro、Taniguchi Atsuhiko、Negishi Yoichi、Hayashi Yoshio
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 10 Issue: 6 Pages: 985-990
- DOI
  10.1021/acsmedchemlett.9b00174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001
[Journal Article] An Efficient Method for the Conjugation of Hydrophilic and Hydrophobic Components by Solid-Phase-Assisted Disulfide Ligation2018
- Author(s)
  Muguruma Kyohei、Shirasaka Takuya、Akiyama Daichi、Fukumoto Kentarou、Taguchi Akihiro、Takayama Kentaro、Taniguchi Atsuhiko、Hayashi Yoshio
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 8 Pages: 2170-2173
- DOI
  10.1002/anie.201712324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13260, KAKENHI-PROJECT-15J09551
[Journal Article] 4‐Fluorophenyl 3‐nitro‐2‐pyridinesulfenate as a practical protecting agent for amino acids2018
- Author(s)
  Yan Cui, Cedric Rentier, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Journal Title
  
  Journal of Peptide Science
  
  Volume: 24 Issue: 3
- DOI
  10.1002/psc.3070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18914, KAKENHI-PROJECT-17K13260
[Journal Article] Near-Infrared Photoactivatable Oxygenation Catalysts of Amyloid Peptide2018
- Author(s)
  Ni Jizhi、Taniguchi Atsuhiko、Ozawa Shuta、Hori Yukiko、Kuninobu Yoichiro、Saito Takashi、Saido Takaomi C.、Tomita Taisuke、Sohma Youhei、Kanai Motomu
- Journal Title
  
  Chem
  
  Volume: 4 Issue: 4 Pages: 807-820
- DOI
  10.1016/j.chempr.2018.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19479, KAKENHI-PROJECT-17K19480, KAKENHI-PROJECT-17K13260, KAKENHI-PLANNED-17H06442, KAKENHI-PROJECT-15H02492, KAKENHI-PROJECT-16H06216, KAKENHI-PROJECT-17H01522
[Journal Article] Amyloid-selective Photooxygenation toward Treatment for Amyloid Diseases2018
- Author(s)
  Taniguchi Atsuhiko
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 1 Pages: 47-53
- DOI
  10.1248/yakushi.17-00186-2
- NAID
  130006300834
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-01-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13260
[Journal Article] Development of Potent Myostatin Inhibitory Peptides through Hydrophobic Residue-Directed Structural Modification2017
- Author(s)
  Takayama Kentaro、Rentier Cedric、Asari Tomo、Nakamura Akari、Saga Yusuke、Shimada Takahiro、Nirasawa Kei、Sasaki Eri、Muguruma Kyohei、Taguchi Akihiro、Taniguchi Atsuhiko、Negishi Yoichi、Hayashi Yoshio
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 8 Issue: 7 Pages: 751-756
- DOI
  10.1021/acsmedchemlett.7b00168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13260, KAKENHI-PROJECT-15H04658, KAKENHI-PROJECT-16F16413
[Patent] シアニン化合物およびその用途2023
- Inventor(s)
  林良雄、谷口敦彦、岡本英之
- Industrial Property Rights Holder
  林良雄、谷口敦彦、岡本英之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-186693
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K06509
[Patent] Curcumin-boron complex and pharmaceutical containing same2017
- Inventor(s)
  Kanai, Soma, Ni, Taniguchi
- Industrial Property Rights Holder
  Kanai, Soma, Ni, Taniguchi
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] 新規オン/オフスイッチ型光酸素化触媒を基盤としたマイオスタチン選択的不活化2024
- Author(s)
  池川馨、岡本英之、村野周子アンバー、山本丈、今野翔、田口晃弘、谷口敦彦、林良雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06509
[Presentation] DASPIを基盤とした新規オン/オフスイッチ型光酸素化触媒の開発2024
- Author(s)
  岡本英之、池川馨、村野周子アンバー、山本丈、今野翔、田口晃弘、谷口敦彦、林良雄
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06509
[Presentation] 酵素耐性型D-ペプチドコンジュゲートを用いた光酸素化によるマイオスタチン阻害2023
- Author(s)
  岡本英之、村野周子アンバー、池川馨、勝山雅大、今野翔、田口晃弘、高山健太郎、谷口敦彦、林良雄
- Organizer
  第40回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-22K06509
[Presentation] 生体内安定性の向上を指向したd-ペプチドと光酸素化触媒からなるマイオスタチン阻害架橋体の開発2023
- Author(s)
  岡本英之、村野周子アンバー、池川馨、勝山雅大、今野翔、田口晃弘、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本ケミカルバイオロジー学会第17年会
- Data Source
  KAKENHI-PROJECT-22K06509
[Presentation] Development of Biocompatible D-Peptide Conjugates for Photooxygenation of Myostatin2023
- Author(s)
  Shuko Amber Murano, Hideyuki Okamoto, Kaoru Ikekawa, Masahiro Katsuyama, Sho Konno, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  The 60th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-22K06509
[Presentation] Inhibition of myostatin by a biocompatible conjugate composed of photooxygenation catalyst and D-peptide2023
- Author(s)
  Kaoru Ikekawa, Hideyuki Okamoto, Shuko Amber Murano, Masahiro Katsuyama, Sho Konno, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  14th AFMC International Medical Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06509
[Presentation] マイオスタチンを光酸素化によって不可逆的に阻害するペプチド-触媒架橋体の開発2023
- Author(s)
  岡本英之、村野周子アンバー、池川馨、勝山雅大、今野翔、田口晃弘、高山健太郎、谷口敦彦、林良雄
- Organizer
  第21回次世代を担う有機化学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06509
[Presentation] マイオスタチンを選択的に光酸素化する短鎖化ペプチドー触媒架橋体の開発2021
- Author(s)
  村野周子アンバー、岡本英之、勝山雅大、今野翔、田口晃弘、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] Efficient Inhibition of Myostatin Activity by Functionalized Peptides with Photooxygenation Catalyst2021
- Author(s)
  H. Okamoto, A. Taniguchi, S. Usami, M. Katsuyama, S. Konno, A. Taguchi, K. Takayama, and Y. Hayashi
- Organizer
  第58回　ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] 標的選択的光酸素化を用いたマイオスタチンの効率的阻害2021
- Author(s)
  谷口敦彦、岡本英之、宇佐美翔哉、勝山雅大、今野翔、田口晃弘、高山健太郎、林良雄
- Organizer
  日本ケミカルバイオロジー学会　第15回年会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] 光酸素化能を付与した機能化ペプチドによるマイオスタチンの活性阻害2021
- Author(s)
  岡本英之、谷口敦彦、宇佐美翔哉、勝山雅大、今野翔、田口晃弘、高山健太郎、林良雄
- Organizer
  創薬懇話会2021
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] Development of peptide-photooxygenation catalyst conjugates that efficiently oxygenate myostatin2021
- Author(s)
  H. Okamoto, A. Taniguchi, S. Usami, M. Katsuyama, S. Konno, A. Taguchi, K. Takayama, and Y. Hayashi
- Organizer
  13th AFMC International Medicinal Chemistry Symposium (AIMECS2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] 光酸素化を利用してマイオスタチンを阻害する機能化ペプチドの開発2021
- Author(s)
  岡本英之、谷口敦彦、宇佐美翔哉、勝山雅大、今野翔、田口晃弘、高山健太郎、林良雄
- Organizer
  日本薬学会141年会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] DESIGN AND SYNTHESIS OF PARTIAL AGONISTS OF HUMAN NEUROMEDIN U RECEPTOR TYPE 1 WITH ENHANCED SERUM STABILITY2020
- Author(s)
  Kentaro Takayama, Kenji Mori, Yuko Sohma, Erina Nomura, Yu Sasaki, Akihiro Taguchi, Atsuhiko Taniguchi, Mikiya Miyazato, Naoto Minamino, Kenji Kangawa, Yoshio Hayashi
- Organizer
  第57回日本ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] MA026の構造訂正とTJ開口活性の作用機構解析2020
- Author(s)
  南雲陽子、向山海凪、内山千尋、福田茜、有本光江、山﨑洋平、加香孝一郎、勝山陽平、谷口敦彦、林良雄、臼井健郎
- Organizer
  第62回天然物有機化合物討論会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] マイクログリアによる光酸素化Aβ代謝促進機構の解明2020
- Author(s)
  小澤柊太、谷口敦彦、清水裕介、王文博、高鳥翔、相馬洋平、金井求、堀由起子、富田泰輔
- Organizer
  第39回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] マイオスタチンを阻害するペプチド-光酸素化触媒コンジュゲートの開発2020
- Author(s)
  岡本英之、谷口敦彦、宇佐美翔哉、勝山雅大、田口晃弘、高山健太郎、林良雄
- Organizer
  第64回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] 標的タンパク質を光酸素化するテイラーメイド機能化ペプチド2020
- Author(s)
  谷口敦彦
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] 筋萎縮治療を指向したマイオスタチン阻害ペプチド封入リポソームに関する基礎的検討2020
- Author(s)
  小田亜倫、濱野展人、谷口敦彦、高山健太郎、林良雄、根岸洋一
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] 光酸素化触媒による機能化ペプチドを用いたマイオスタチン阻害2019
- Author(s)
  宇佐美翔哉、岡本英之、谷口敦彦、田口晃弘、高山健太郎、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] ペプチド-光酸素化触媒コンジュゲートを用いたマイオスタチンの活性阻害2019
- Author(s)
  岡本英之, 谷口敦彦, 宇佐美翔哉, 田口晃弘, 高山健太郎, 林良雄
- Organizer
  日本薬学会第 139 年会
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] Inactivation of myostatin by photooxygenation using catalyst-peptide conjugate2019
- Author(s)
  A. Taniguchi, H. Okamoto, S. Usami, A. Taguchi, K. Takayama, and Y. Hayashi
- Organizer
  12th Asian Federation for Medicinal Chemistry (AFMC) International Medicinal Chemistry Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] Inhibition of myostatin activity by peptide-photooxygenation catalyst conjugate2019
- Author(s)
  H. Okamoto, A. Taniguchi, S. Usami, A. Taguchi, K. Takayama, and Y. Hayashi
- Organizer
  26th American Peptide Symposium and 11th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] ペプチド-光酸素化触媒コンジュゲートを用いたマイオスタチンの不活化2019
- Author(s)
  谷口敦彦、岡本英之、宇佐美翔哉、田口晃弘、高山健太郎、林良雄
- Organizer
  日本ケミカルバイオロジー学会　第14回年会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] Selective photooxygenation of myostatin using peptide-catalyst conjugate2019
- Author(s)
  A. Taniguchi, H. Okamoto, S. Usami, A. Taguchi, K. Takayama, and Y. Hayashi
- Organizer
  11th Joint Meeting of Medicinal Chemistry 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] Inactivation of Myostatin Using Peptide Functionalized by Photooxygenation Catalyst2019
- Author(s)
  A. Taniguchi, H. Okamoto, S. Usami, A. Taguchi, K. Takayama, and Y. Hayashi
- Organizer
  第56回　ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] Inactivation of myostatin using photooxygenation catalyst-peptide conjugate2019
- Author(s)
  A. Taniguchi, H. Okamoto, S. Usami, A. Taguchi, K. Takayama, and Y. Hayashi
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07001
[Presentation] 網羅的構造活性相関研究によるマウス由来マイオスタチン阻害ペプチドの高活性化2018
- Author(s)
  高山健太郎，淺利知，齋藤まりこ，六本木佳美，中村明里，嶋田嵩大，池山弘晃，田口晃弘，谷口敦彦，根岸洋一，林良雄
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] Structural requirements for the effective myostatin inhibition of myostatin prodomain-derived peptide derivatives2018
- Author(s)
  K. Takayama, T. Asari, M. Saitoh, Y. Roppongi, A. Nakamura, A. Taguchi, A. Taniguchi, Y. Hayashi
- Organizer
  256th American Chemical Society National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] マイオスタチン阻害を目指したペプチド-光酸素化触媒コンジュゲートの開発2018
- Author(s)
  岡本英之，谷口敦彦，宇佐美翔哉，田口晃弘，高山健太郎，林良雄
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] ジスルフィド先導型環状ペプチド合成法による生理活性ペプチドの効率的合成2018
- Author(s)
  飯田　啓斗，田口　晃弘，崔　岩，福元　早穂子，小林　清孝，倉石　彩恵香，高山　健太郎，谷口　敦彦，林　良雄
- Organizer
  日本薬学会第 138 年会
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] Structural requirements of mouse myostatin prodomain-derived small peptide for effective myostatin inhibition2018
- Author(s)
  K. Takayama, T. Asari, M. Saitoh, Y. Roppongi, A. Nakamura, A. T. Shimada, Taguchi, A. Taniguchi, Y. Negishi, Y. Hayashi
- Organizer
  8th Peptide Engineering Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] 小型化マイオスタチン阻害ペプチドの発見と高活性誘導体の創製2018
- Author(s)
  六本木佳美、高山健太郎、齊藤まりこ、中村明里、嶋田嵩大、田口晃弘、谷口敦彦、根岸洋一、林良雄
- Organizer
  創薬懇話会2017 in 志賀島
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] Structural derivatization for the effective myostatin inhibition of myostatin prodomain-derived peptide derivatives2018
- Author(s)
  K. Takayama, T. Asari, M. Saitoh, Y. Roppongi, A. Nakamura, A. Taguchi, A. Taniguchi, Y. Negishi, Y. Hayashi
- Organizer
  11th Japanese-French Workshop “New insights in personalized medicine for neuromuscular diseases: From Basic to Applied Myology”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] Development of Peptide-Catalyst Conjugate for Photooxygenation of Myostatin2018
- Author(s)
  H. Okamoto, A. Taniguchi, S. Usami, A. Taniguchi, K. Takayama, Y. Hayashi
- Organizer
  10th International Peptide Symposium / 55th Japanese Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] 小型化マイオスタチン阻害ペプチドの発見と高活性化2018
- Author(s)
  齊藤　まりこ、高山　健太郎、C. Rentier、中村　明里、嶋田　嵩大、六本木　佳美、田口　晃弘、谷口　敦彦、根岸　洋一、林良雄
- Organizer
  日本薬学会第 138 年会
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] マイオスタチン阻害ペプチドの小型化と構造活性相関研究2018
- Author(s)
  高山健太郎、淺利知、齋藤まりこ、六本木佳美、中村明里、佐賀裕介、嶋田嵩大、池山弘晃、田口晃弘、谷口敦彦、根岸洋一、林良雄
- Organizer
  日本筋学会第4回学術集会
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] 固相ジスルフィド架橋試薬を用いたペプチド－薬物架橋体の合成2017
- Author(s)
  六車　共平、白坂　拓也、秋山　大地、田口　晃弘、高山　健太郎、谷口　敦彦、林　良雄
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] 環状ジスルフィドペプチドの効率的合成を指向した新規ジスルフィド架橋試薬の創製2017
- Author(s)
  小林　清孝、田口　晃弘、小谷　明、六車　共平、小林　美咲、崔　岩、福元　謙太郎、高山　健太郎、谷口　敦彦、袴田　秀樹、林　良雄
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] マイオスタチン阻害ペプチドの活性強化を目指した網羅的構造活性相関研究2017
- Author(s)
  高山　健太郎、池山　弘晃、C. Rentier、中村　明里、佐賀　裕介、嶋田　嵩大、齋藤　まりこ、田口　晃弘、谷口　敦彦、根岸　洋一、林　良雄
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] マイオスタチン阻害ペプチドの活性強化を指向した構造活性相関研究2017
- Author(s)
  六本木　佳美、高山　健太郎、C. Rentier、中村　明里、佐賀　裕介、嶋田　嵩大、齋藤　まりこ、田口　晃弘、谷口　敦彦、根岸　洋一、林　良雄
- Organizer
  日本ケミカルバイオロジー学会第１２回年会
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] マイオスタチン阻害ペプチドの活性強化を目指した構造活性相関研究2017
- Author(s)
  高山　健太郎、C. Rentier、淺利　知、中村　明里、佐賀　裕介、嶋田　嵩大、齋藤　まりこ、六本木　佳美、田口　晃弘、谷口　敦彦、根岸　洋一、林　良雄
- Organizer
  日本筋学会第3回学術集会
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] Development of a disulfide bond-forming agent toward efficient multi-disulfide peptide synthesis2017
- Author(s)
  K. Kobayashi, A. Taguchi, A. Kotani, K. Muguruma, M. Kobayashi, Y. Cui, K. Fukumoto, K. Takayama, H. Hakamata, A. Taniguchi, Y. Hayashi
- Organizer
  3rd Annual Peptides and Proteins Symposium Singapore (P2S2-2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13260
[Presentation] Development of a new method on Npys-based disulfide bond formation for the preparation of bioactive cyclic disulfide peptides2017
- Author(s)
  A. Taguchi, K. Kobayashi, A. Kotani, K. Muguruma, M. Kobayashi, K. Fukumoto, K. Takayama, A. Taniguchi, H. Hakamata, Y. Hayashi
- Organizer
  12th Annual Peptide Therapeutics Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13260

1. 林良雄 (10322562)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
2. 遠藤玉夫 (30168827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 田村純一 (30221401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小林千浩 (90324780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 神谷亘 (60551421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 今野翔 (70882190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAYAMA Kentaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
8. 堀由起子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 田口晃弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 金井求

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Taniguchi Atsuhiko 谷口 敦彦

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ラミニン結合性機能糖鎖を応用した筋ジストロフィーに対する創薬研究

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Development of innovative drug discovery based on SARS-CoV-2 3CL protease inhibitor YH-53

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選択的光酸素化を基盤とした汎用的タンパク質不活化法~新規抗ウイルス戦略への展開~Principal Investigator

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Inhibition of protein interaction with selective photooxygenationPrincipal Investigator

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Control of TGF-beta related protein based on selective photooxygenationPrincipal Investigator

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[Journal Article] Establishment of One-Pot Disulfide-Driven Cyclic Peptide Synthesis with a 3-Nitro-2-pyridinesulfenate2023

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[Journal Article] Development of Myostatin Inhibitory d-Peptides to Enhance the Potency, Increasing Skeletal Muscle Mass in Mice2022

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[Journal Article] Strategic structure-activity relationship study on a follistatin-derived myostatin inhibitory peptide2021

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[Journal Article] Synthesis and biological evaluation of a monocyclic Fc-binding antibody-recruiting molecule for cancer immunotherapy2021

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[Journal Article] Proposal for the binding mode of the 23-mer inhibitory peptide to myostatin2021

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[Journal Article] Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation2021

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[Journal Article] Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application2021

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[Journal Article] “On‐Resin” Disulfide Peptide Synthesis with Methyl 3‐Nitro‐2‐pyridinesulfenate2021

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[Journal Article] Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in the brains of Alzheimer’s disease model mice2021

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Taniguchi Atsuhiko 谷口敦彦