Shibahara Ichiyo 柴原一陽

… Alternative Names

Ichiyo Shibahara 柴原一陽

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Researcher Number	30791016
Other IDs
Affiliation (Current)	2026: 北里大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 北里大学, 医学部, 准教授 2019 – 2023: 北里大学, 医学部, 講師 2018: 北里大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator 播種 / 膠芽腫 / 高感度DNA解析 / cell free DNA / 髄液 / マルチオミクス / プロテオミクス解析 / RNAシーケンス / エクソーム解析 / 全エクソームシーケンス … More Except Principal Investigator … More 膠芽腫 / メカノトランスダクション / グリオーマ / アクチン細胞骨格 / YAP / 脳腫瘍 / メカノセンシング / 新規治療 / ボーダーニッチ / 脳幹 / Border Niche / オリゴデンドロサイト / ニューロン / 微小環境 / がん幹細胞 Less

Development of a Highly Sensitive DNA Analysis Method for the Clinical Application of Ultra-Low–Input Cell-Free DNAPrincipal Investigator
- Principal Investigator
  
  柴原一陽
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kitasato University
Elucidation of the mechanism of tumor formation through mechanosensory defects
- Principal Investigator
  
  堤弘次
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kitasato University
稀少臨床検体に注目した膠芽腫播種病態解明のためのマルチオミックス解析Principal Investigator
- Principal Investigator
  
  柴原一陽
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kitasato University
Investigation of new treatment strategies for glioblastoma focusing on the interaction with oligodendrocytes and neurons
- Principal Investigator
  
  Hide Takuichiro
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kitasato University
Identification of genes associated with glioblastoma dissemination using whole genome sequencingPrincipal Investigator
- Principal Investigator
  
  Ichiyo Shibahara
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kitasato University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Radiological, clinical, and molecular analyses reveal distinct subtypes of butterfly glioblastomas affecting the prognosis2024
- Author(s)
  Shibahara Ichiyo、Shigeeda Ryota、Watanabe Takashi、Orihashi Yasushi、Tanihata Yoko、Fujitani Kazuko、Handa Hajime、Hyakutake Yuri、Toyoda Mariko、Inukai Madoka、Uemasu Kohei、Shinoda Mitsuhiro、Komai Hideto、Sato Sumito、Hide Takuichiro、Kumabe Toshihiro
- Journal Title
  
  Neuro-Oncology Advances
  
  Volume: 6 Issue: 1 Pages: 1-14
- DOI
  10.1093/noajnl/vdae180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09291
[Journal Article] Clinical and molecular features of patients with IDH1 wild-type primary glioblastoma presenting unexpected short-term survival after gross total resection.2024
- Author(s)
  2.Toyoda M, Shibahara I, Shigeeda R, Fujitani K, Tanihata Y, Hyakutake Y, Handa H, Komai H, Sato S, Inukai M, Hide T, Shimoda Y, Kanamori M, Endo H, Saito R, Matsuda KI, Sonoda Y, Kumabe T.
- Journal Title
  
  J Neurooncol.
  
  Volume: 169(1) Issue: 1 Pages: 39-50
- DOI
  10.1007/s11060-024-04687-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09374, KAKENHI-PROJECT-24K12270
[Journal Article] Evolving driver mutations in adult-onset SHH-medulloblastoma originated from radiological cerebellar abnormality2024
- Author(s)
  Shibahara Ichiyo、Nakashima Takuma、Toyoda Mariko、Inukai Madoka、Matsumoto Toshihide、Fujitani Kazuko、Tanihata Yoko、Hide Takuichiro、Fuse Nobuo、Suzuki Hiromichi、Kumabe Toshihiro
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 83 Issue: 9 Pages: 791-794
- DOI
  10.1093/jnen/nlae051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24449, KAKENHI-PROJECT-20K09374, KAKENHI-PROJECT-23K06472
[Journal Article] Ventricular opening and cerebrospinal fluid circulation accelerate the biodegradation process of carmustine wafers suggesting their immunomodulation potential in the human brain2022
- Author(s)
  Shibahara Ichiyo、Shibahara Yukiko、Hagiwara Hiroyuki、Watanabe Takashi、Orihashi Yasushi、Handa Hajime、Inukai Madoka、Hide Takuichiro、Yasui Yoshie、Kumabe Toshihiro
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 159 Issue: 2 Pages: 425-435
- DOI
  10.1007/s11060-022-04078-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09374, KAKENHI-PROJECT-18K16569
[Journal Article] Anatomical and neurophysiological localization of the leg motor area at the medial central sulcus2022
- Author(s)
  Sato Sumito、Shibahara Ichiyo、Inukai Madoka、Komai Hideto、Hide Takuichiro、Kumabe Toshihiro
- Journal Title
  
  Clinical Neurophysiology
  
  Volume: 143 Pages: 67-74
- DOI
  10.1016/j.clinph.2022.08.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09374
[Journal Article] Ribosomal proteins induce stem cell-like characteristics in glioma cells as an “extra-ribosomal function”2022
- Author(s)
  Takuichiro Hide, Ichiyo Shibahara, Madoka Inukai, Ryota Shigeeda, Yuki Shirakawa, Hirofumi Jono, Naoki Shinojima, Akitake Mukasa, and Toshihiro Kumabe
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09374
[Journal Article] Ribosomal proteins induce stem cell-like characteristics in glioma cells as an “extra-ribosomal function”2022
- Author(s)
  Hide Takuichiro、Shibahara Ichiyo、Inukai Madoka、Shigeeda Ryota、Shirakawa Yuki、Jono Hirofumi、Shinojima Naoki、Mukasa Akitake、Kumabe Toshihiro
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 39 Issue: 2 Pages: 51-56
- DOI
  10.1007/s10014-022-00434-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09374, KAKENHI-PROJECT-22K15400, KAKENHI-PROJECT-20H03792
[Journal Article] Role of the parietooccipital fissure and its implications in the pathophysiology of posterior medial temporal gliomas2022
- Author(s)
  Shibahara Ichiyo、Saito Ryuta、Kanamori Masayuki、Sonoda Yukihiko、Sato Sumito、Hide Takuichiro、Tominaga Teiji、Kumabe Toshihiro
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: 137 Issue: 2 Pages: 505-514
- DOI
  10.3171/2021.7.jns21990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16569
[Journal Article] Ribosomes and Ribosomal Proteins Promote Plasticity and Stemness Induction in Glioma Cells via Reprogramming2022
- Author(s)
  Hide Takuichiro、Shibahara Ichiyo、Inukai Madoka、Shigeeda Ryota、Kumabe Toshihiro
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 14 Pages: 2142-2142
- DOI
  10.3390/cells11142142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09374
[Journal Article] Long-term follow-up after BCNU wafer implantation in patients with newly diagnosed glioblastoma2021
- Author(s)
  Shibahara I, Miyasaka K, Sekiguchi A, Ishiyama H, Inukai M, Yasui Y, Watanabe T, Sato S, Hide T, Kumabe T.
- Journal Title
  
  Journal of Clinical Neuroscience.
  
  Volume: 86 Pages: 202-210
- DOI
  10.1016/j.jocn.2021.01.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09374, KAKENHI-PROJECT-18K16569
[Journal Article] Postcentral gyrus resection of opercular gliomas is a risk factor for motor deficits caused by damaging the radiologically invisible arteries supplying the descending motor pathway2021
- Author(s)
  Shibahara Ichiyo、Sato Sumito、Hide Takuichiro、Saito Ryuta、Kanamori Masayuki、Sonoda Yukihiko、Tominaga Teiji、Kumabe Toshihiro
- Journal Title
  
  Acta Neurochirurgica
  
  Volume: - Issue: 5 Pages: 1269-1278
- DOI
  10.1007/s00701-021-04737-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16569
[Journal Article] Temporal Glioblastoma Mimicking Basal Ganglia Invasion: Distinguishing Removable and Unremovable Tumors2019
- Author(s)
  Ichiyo Shibahara 1, Mitsuto Hanihara, Kazuhiro Miyasaka, Sumito Sato, Takuichiro Hide, Toshihiro Kumabe
- Journal Title
  
  World Neurosurgery
  
  Volume: 130 Pages: e213-e221
- DOI
  10.1016/j.wneu.2019.06.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16569
[Presentation] Ribosomal protein S6はextra-ribosomal functionとして膠芽腫細胞に幹細胞性を誘導する2023
- Author(s)
  秀拓一郎，柴原一陽，犬飼円，重枝諒太，隈部俊宏
- Organizer
  第23回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-20K09374
[Presentation] 外因性リボゾームは膠芽腫細胞の可塑性や幹細胞性に関与する2022
- Author(s)
  秀拓一郎，白川裕貴，城野博史，柴原一陽，犬飼円，篠島直樹，武笠晃丈，斎藤秀之，隈部俊宏
- Organizer
  第39回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-20K09374
[Presentation] 治療標的としての膠芽腫幹細胞ニッチでの細胞間コミュニケーション2021
- Author(s)
  秀拓一郎，白川裕貴，城野博史，柴原一陽，武笠晃丈，斎藤秀之，隈部俊宏
- Organizer
  第126回日本解剖学会・第98回日本生理学会大会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09374
[Presentation] リボゾームは膠芽腫細胞に幹細胞性を誘導する2021
- Author(s)
  秀拓一郎、白川裕貴、城野博史、柴原一陽、犬飼円、篠島直樹、武笠晃丈、隈部俊宏
- Organizer
  第39回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-20K09374
[Presentation] 治療標的としての膠芽腫幹細胞ニッチでの細胞間コミュニケーション2021
- Author(s)
  秀拓一郎、白川裕貴、城野博史、柴原一陽、武笠晃丈、斎藤秀之、隈部俊宏
- Organizer
  第126回日本解剖学会，第98回日本生理学会大会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09374
[Presentation] 膠芽腫幹細胞ニッチでの細胞間コミュニケーション2020
- Author(s)
  秀拓一郎，白川裕貴，城野博史，柴原一陽，犬飼円，篠島直樹，武笠晃丈，隈部俊宏
- Organizer
  第38回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09374

1. Hide Takuichiro (40421820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 隈部俊宏 (10250747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. 犬飼円 (10525695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 小寺義男 (60265733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 三浦史仁 (50447348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 堤弘次 (50569853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 関田洋一 (20431950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鈴木啓道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibahara Ichiyo 柴原 一陽

Ichiyo Shibahara 柴原 一陽

Research Projects

Research Products

Co-Researchers

Development of a Highly Sensitive DNA Analysis Method for the Clinical Application of Ultra-Low&#8211;Input Cell-Free DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of tumor formation through mechanosensory defects

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

稀少臨床検体に注目した膠芽腫播種病態解明のためのマルチオミックス解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of new treatment strategies for glioblastoma focusing on the interaction with oligodendrocytes and neurons

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of genes associated with glioblastoma dissemination using whole genome sequencingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Radiological, clinical, and molecular analyses reveal distinct subtypes of butterfly glioblastomas affecting the prognosis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and molecular features of patients with IDH1 wild-type primary glioblastoma presenting unexpected short-term survival after gross total resection.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evolving driver mutations in adult-onset SHH-medulloblastoma originated from radiological cerebellar abnormality2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ventricular opening and cerebrospinal fluid circulation accelerate the biodegradation process of carmustine wafers suggesting their immunomodulation potential in the human brain2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anatomical and neurophysiological localization of the leg motor area at the medial central sulcus2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ribosomal proteins induce stem cell-like characteristics in glioma cells as an “extra-ribosomal function”2022

Author(s)

Journal Title

Data Source

[Journal Article] Ribosomal proteins induce stem cell-like characteristics in glioma cells as an “extra-ribosomal function”2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the parietooccipital fissure and its implications in the pathophysiology of posterior medial temporal gliomas2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ribosomes and Ribosomal Proteins Promote Plasticity and Stemness Induction in Glioma Cells via Reprogramming2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term follow-up after BCNU wafer implantation in patients with newly diagnosed glioblastoma2021

Shibahara Ichiyo 柴原一陽

Ichiyo Shibahara 柴原一陽

Development of a Highly Sensitive DNA Analysis Method for the Clinical Application of Ultra-Low–Input Cell-Free DNAPrincipal Investigator