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aoki takahiro  青木 孝浩

… Alternative Names

Aoki Takahiro  青木 孝浩

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Researcher Number 30791553
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9148-2871
Affiliation (Current) 2026: 千葉大学, 大学院医学研究院, 助教
Affiliation (based on the past Project Information) *help 2026: 千葉大学, 大学院医学研究院, 助教
2022 – 2023: 千葉大学, 大学院医学研究院, 助教
2020 – 2021: 国立研究開発法人理化学研究所, 生命医科学研究センター, 特別研究員
2019: 帝京大学, 医学部, 助教
2018: 千葉大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
NKT細胞 / iPS細胞 / NK受容体 / 白血病 / 免疫療法 / iPS-NKT細胞 / がん免疫 / 認識分子 / CRISPR library / 腫瘍認識分子 / CRISPRライブラリー / iNKT細胞 / CD1d
  • Research Projects

    (4 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (1 People)
  •  iPS細胞由来NKT細胞を利用した腫瘍特異的T細胞養子免疫療法の開発Principal Investigator

    • Principal Investigator
      青木 孝浩
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Chiba University
  •  Combination therapy of iPS-NKT cells and alpha-GalCer-pulsed antigen-presenting cells for leukemiaPrincipal Investigator

    • Principal Investigator
      青木 孝浩
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Chiba University
  •  Identification of molecules recognized by invariant NKT cells independently of CD1dPrincipal Investigator

    • Principal Investigator
      Aoki Takahiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Chiba University
      Institute of Physical and Chemical Research
  •  Tumor recognition mechanism of NKT cells for CD1d-negative leukemia cellsPrincipal Investigator

    • Principal Investigator
      Aoki Takahiro
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Teikyo University
      Chiba University

All 2024 2023 2022 2020 2019

All Journal Article Presentation

  • [Journal Article] Progress in Natural Killer T Cell-Based Immunotherapy for Cancer: Use of Allogeneic and Gene-Edited Cells2024

    • Author(s)
      Aoki Takahiro、Motohashi Shinichiro
    • Journal Title

      Critical Reviews in Oncogenesis

      Volume: 29 Issue: 1 Pages: 1-9

    • DOI

      10.1615/critrevoncog.2023049526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24441, KAKENHI-PROJECT-23K07827
  • [Journal Article] 臨床開発ステージに進んだ新たながん免疫療法 iPS細胞由来NKT細胞を用いた免疫療法2023

    • Author(s)
      青木孝浩、本橋新一郎
    • Journal Title

      腫瘍内科

      Volume: 31 Pages: 334-340

    • Data Source
      KAKENHI-PROJECT-23K07827
  • [Journal Article] Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy2023

    • Author(s)
      Aoki Takahiro、Motohashi Shinichiro、Koseki Haruhiko
    • Journal Title

      Inflammation and Regeneration

      Volume: 43 Issue: 1 Pages: 27-27

    • DOI

      10.1186/s41232-023-00275-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24441, KAKENHI-PROJECT-23K07827
  • [Journal Article] 他家NKT 細胞を用いた免疫細胞療法の開発2023

    • Author(s)
      青木孝浩、本橋新一郎
    • Journal Title

      癌と化学療法

      Volume: 50 Pages: 584-588

    • Data Source
      KAKENHI-PROJECT-23K07827
  • [Journal Article] iPS細胞由来NKT細胞を利用したがん免疫療法2022

    • Author(s)
      青木孝浩、本橋新一郎
    • Journal Title

      Medical Technology

      Volume: 50 Pages: 1164-1166

    • Data Source
      KAKENHI-PROJECT-20K17408
  • [Journal Article] 細胞療法の新しい戦略 幹細胞ベース iPS細胞由来NKT細胞2020

    • Author(s)
      青木孝浩、古関明彦
    • Journal Title

      実験医学

      Volume: 38 Pages: 2956-2962

    • Data Source
      KAKENHI-PROJECT-20K17408
  • [Journal Article] 再生医療の応用による免疫リプログラミング iPS細胞を用いたNKT細胞再生と治療2020

    • Author(s)
      青木孝浩、古関明彦
    • Journal Title

      医学のあゆみ

      Volume: 275 Pages: 67-72

    • Data Source
      KAKENHI-PROJECT-20K17408
  • [Presentation] Activation of iPS cell-derived NKT cells demonstrates indirect cytotoxicity by inducing stem-like T cells2024

    • Author(s)
      Takahiro Aoki
    • Organizer
      CD1-MR1 workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07827
  • [Presentation] Development of iPS cell-derived NKT cell therapy for regenerating the adjuvant effect2024

    • Author(s)
      古関明彦、青木孝浩
    • Organizer
      日本再生医療学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K07827
  • [Presentation] iPS cell-derived NKT cells retain the adjuvant activity of inducing memory phenotype T cells2024

    • Author(s)
      青木孝浩
    • Organizer
      日本免疫学会
    • Data Source
      KAKENHI-PROJECT-23K07827
  • [Presentation] iPS cell-derived NKT cells show indirect anti-tumor effect with inducing tumor-reactive T cells with memory phenotype2023

    • Author(s)
      青木孝浩
    • Organizer
      日本がん免疫学会
    • Data Source
      KAKENHI-PROJECT-23K07827
  • [Presentation] Preclinical efficacy of iPS cell-derived NKT cell therapy with alpha-galactosylceramide-loaded antigen-presenting cells2023

    • Author(s)
      青木孝浩
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-23K07827
  • [Presentation] Alpha-galactosylceramide-loaded antigen-presenting cells induce direct cytotoxicity and adjuvant effects of induced pluripotent stem cell-derived natural killer T cells2022

    • Author(s)
      Takahiro Aoki, Genta Kitahara, Momoko Okoshi, Midori Kobayashi, Munechika Yamaguchi, Hiroko Okura, Nayuta Yakushiji, Masami Kawamura, Tomonori Iyoda, Kanako Shimizu, Shin-ichiro Fujii, Shinichiro Motohashi, Haruhiko Koseki
    • Organizer
      Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-20K17408
  • [Presentation] The iPS cell-derived NKT cell therapy with aGalCer-loaded dendritic cells for solid tumors2022

    • Author(s)
      Takahiro Aoki, Genta Kitahara, Midori Kobayashi, Momoko Okoshi, Munechika Yamaguchi, Hiroko Okura, Nayuta Yakushiji, Masami Kawamura, Tomonori Iyoda, Kanako Shimizu, Shin-ichiro Fujii, Shinichiro Motohashi, Haruhiko Koseki
    • Organizer
      Japanese Society for Transplantation and Cellular Therapy
    • Data Source
      KAKENHI-PROJECT-20K17408
  • [Presentation] Invariant NKT cells target CD1d-negative leukemia cells with TCR and NK receptors.2019

    • Author(s)
      Takahiro Aoki, Mariko Takami, Tomozumi Takatani, Kiwamu Motoyoshi, Ayana Ishii, Reona Okada, Moeko Hino, Naoki Shimojo, Shinichiro Motohashi.
    • Organizer
      EMBO Workshop - CD1-MR1.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16108
  • [Presentation] Invariant NKT Cells Recognize Leukemia Cells with T-Cell and NK Receptors in a CD1d-Independent Manner.2019

    • Author(s)
      Takahiro Aoki, Mariko Takami, Tomozumi Takatani, Kiwamu Motoyoshi, Ayana Ishii, Ayaka Hara, Takahide Toyoda, Reona Okada, Moeko Hino, Ryo Koyama-Nasu, Masahiro Kiuchi, Kiyoshi Hirahara, Toshinori Nakayama, Naoki Shimojo, Shinichiro Motohashi.
    • Organizer
      The 61th ASH annual meeting and exposition.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16108
  • [Presentation] Invariant NKT cellsrecognize leukemia cells in a CD1d independent manner.2019

    • Author(s)
      Takahiro Aoki, Mariko Takami, Tomozumi Takatani, Kiwamu Motoyoshi, Ayana Ishii, Reona Okada, Moeko Hino, Naoki Shimojo, Shinichiro Motohashi.
    • Organizer
      第23回日本がん免疫学会総会.
    • Data Source
      KAKENHI-PROJECT-18K16108
  • 1.  MOTOHASHI Shinichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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