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Yamagishi Ryota  山岸 良多

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yamagishi ryota  山岸 良多

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Researcher Number 30793145
Affiliation (Current) 2025: 大阪公立大学, 大学院医学研究科, 講師
Affiliation (based on the past Project Information) *help 2023: 大阪公立大学, 大学院医学研究科, 講師
2022: 大阪公立大学, 大学院医学研究科, 助教
2017 – 2021: 大阪市立大学, 大学院医学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Tumor therapeutics
Keywords
Principal Investigator
GSDMD / 細胞老化 / SASP / 肥満誘導性肝がん / mRNA代謝 / ガスダーミン / 肝星細胞 / mRNA代謝制御 / mRNA安定性 / 合成致死 / 悪性中皮腫
  • Research Projects

    (3 results)
  • Research Products

    (29 results)
  •  パイロトーシス実行因子GSDMDを標的としたCAF化肝星細胞排除法の開発Principal Investigator

    • Principal Investigator
      山岸 良多
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Osaka Metropolitan University
  •  Search for new therapeutic targets for obesity-induced liver cancer focusing on mRNA degradation regulationPrincipal Investigator

    • Principal Investigator
      Yamagishi Ryota
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Osaka Metropolitan University
      Osaka City University
  •  Screening of synthetic lethal gene to causative gene of mesotheliomaScreening of synthetic lethal gene to causative gene of mesotheliomaPrincipal Investigator

    • Principal Investigator
      yamagishi ryota
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Osaka City University

All 2024 2023 2022 2021 2020 Other

All Presentation Patent Other

  • [Patent] 固形がんの予防及び/又は治療薬2022

    • Inventor(s)
      大谷直子、山岸良多
    • Industrial Property Rights Holder
      大谷直子、山岸良多
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] Identification of tumor-promoting secreted factors in the progression of steatosis-associated HCC2024

    • Author(s)
      Atsuki Uno, Yoshiki Nonaka, Kanae Echizen, Ryota Yamagishi, Takahiro Kodama, Naoko Ohatani
    • Organizer
      APASL 2024 Kyota (The 33rd Annual Meeting of the Asian Pacific Association)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06655
  • [Presentation] Hepatic Carcinogenesis and Immune Response Involving Gut microbial metabolites2023

    • Author(s)
      Ryota Yamagishi, Fumitaka Kamachi, Yi Cheng, Norifumi Kawada, Eiji Hara, Naoko Ohtani
    • Organizer
      第82回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06655
  • [Presentation] がん微小環境における細胞老化とSASPの役割:ガスダーミンDを介するSASP因子の放出が肥満関連肝がんを促進させる2023

    • Author(s)
      山岸良多、蒲池史卓、神谷知憲、高杉征樹、程イ、野中允幾、河田則文、中江進、原英二、大谷直子
    • Organizer
      日本生理学会第100回記念大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] IL-33 による NASH 関連肝がん促進機構の解明2023

    • Author(s)
      山岸良多,大谷直子
    • Organizer
      第27回日本がん分子治療標的学会
    • Data Source
      KAKENHI-PROJECT-23K06655
  • [Presentation] 肥満誘導性肝臓がん微小環境におけるがん促進的経路に着目した機能的インタラクトーム解析2023

    • Author(s)
      宇野敦葵,野中允幾,越前佳奈恵,山岸良多,程イ,大谷直子
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K06655
  • [Presentation] 規則的な運動はオンコメタボライトKynurenineを減少させることで肥満誘導性肝がんの進展を抑制する2023

    • Author(s)
      ヴ トゥンフェン,山岸 良多,大谷 直子
    • Organizer
      第27回日本がん分子治療標的学会
    • Data Source
      KAKENHI-PROJECT-23K06655
  • [Presentation] 肥満誘導性肝がん微小環境におけるがん進展過程を考慮したネットワーク2023

    • Author(s)
      野中允幾, 宇野敦葵,越前佳奈恵, 山岸良多, 大谷直子
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K06655
  • [Presentation] 運動による代謝変化を介したNASH関連肝がん抑制機構2023

    • Author(s)
      山岸良多,大谷直子
    • Organizer
      第45回日本臨床栄養学会総会・第44回日本臨床栄養協会総会 第21回大連合大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06655
  • [Presentation] IL-33によるNASH関連肝がん促進機構、山岸良多、武藤芳美、河田則文、大谷直子、第59回日本肝臓学会総会2022

    • Author(s)
      山岸良多、武藤芳美、河田則文、大谷直子
    • Organizer
      第59回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] 肥満誘導性肝がん微小環境における腫瘍促進ネットワークの複合解析2022

    • Author(s)
      野中允幾、 山岸良多、 程イ、 小玉尚宏、 大谷直子
    • Organizer
      NGS EXPO 2022
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] 肥満誘導性肝がん微小環境における腫瘍促進ネットワークの複合バイオインフォマティクス解析2022

    • Author(s)
      野中允幾、 山岸良多、 程イ、 大谷直子
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] IL-33 released from senescent hepatic stellate cell promotes obesity-associated hepatocellular carcinoma2022

    • Author(s)
      Ryota Yamagishi, Fumitaka Kamachi, Yi Cheng, Norifumi Kawada, Eiji Hara, Naoko Ohtani
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] Regular exercise suppresses obesity associated liver cancer through activating Pgc-1α-Kynurenine degrading pathway2022

    • Author(s)
      Vu Thuong Huyen, Ryota Yamagishi, Naoko Ohtani
    • Organizer
      APASL Oncology 2022 Single Topic conference in Takamatsu
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] IL-33 released from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma2022

    • Author(s)
      Ryota Yamagishi, Fumitaka Kamachi, Tomonori Kamiya, Yi Cheng, Yoshiki Nonaka, Norifumi Kawada, Susumu Nakae, Eiji Hara, Naoko Ohtani
    • Organizer
      APASL Oncology 2022 Single Topic conference in Takamatsu
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] Regular exercise suppresses obesity associated liver cancer through activating Pgc-1α-Kynurenine degrading pathway2022

    • Author(s)
      Vu Thuong Huyen, Ryota Yamagishi, Naoko Ohtani
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] Combined Bioinformatics on the Tumor Promoting Inter-cellular Network in Obesity-associated Liver Tumor Microenvironment2022

    • Author(s)
      Yoshiki Nonaka, Ryota Yamagishi, Yi Cheng, Naoko Ohtani
    • Organizer
      APASL Oncology 2022 Single Topic conference in Takamatsu
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] Gut-liver Axis-mediated Mechanism of NASH-associated Hepatocellular Carcinoma Progression2021

    • Author(s)
      Ryota Yamagishi, Fumitaka Kamachi, Tomonori Kamiya, Yoshiki Nonaka, Yoshimi Muto-Yukawa, Norifumi Kawada, Susumu Nakae, Eiji Hara, Naoko Ohtani
    • Organizer
      APASL Single Topic Conference 2021 Osaka
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] Gut-liver axis-mediated mechanism of NASH-associated hepatocellular carcinoma progression2021

    • Author(s)
      Ryota Yamagishi, Fumitaka Kamachi, Tomonori Kamiya, Yoshiki Nonaka, Yoshimi Muto-Yukawa, Norifumi Kawada, Susumu Nakae, Eiji Hara, Naoko Ohtani
    • Organizer
      6th International Cell Senescence Association (ICSA) Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] シングルセル解析を利用した肥満誘導性肝がん微小環境における肝星細胞の系譜・性質解明2021

    • Author(s)
      野中 允幾、山岸 良多、大谷 直子
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] A Novel Isolation Method of Hepatic Stellate Cells from Tumor Tissue of Obesity-associated Hepatocellular Carcinoma2021

    • Author(s)
      Yi Cheng, Ryota Yamagishi, Yoshiki Nonaka, Huyen T. Vu, Yoshimi Yukawa-Muto, Misako Sato-Matsubara, Norifumi Kawada, Naoko Ohtani
    • Organizer
      APASL Single Topic Conference 2021 Osaka
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] enescence phenotype in freshly isolated hepatic stellate cells (HSCs) by non-heat-stressed method from obesity-associated steatotic hepatocellular carcinoma2021

    • Author(s)
      Yi Cheng, Ryota Yamagishi, Yoshiki Nonaka, Naoko Ohtani
    • Organizer
      6th International Cell Senescence Association (ICSA) Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] 肥満関連肝癌腫瘍組織からの肝星細胞の分離法2021

    • Author(s)
      程 イ、大谷 直子、山岸 良多、蒲池 史卓
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] LATS2変異を有した悪性中皮腫におけるSMG6発現抑制による合成致死誘導機構の検討2020

    • Author(s)
      鈴木 浩也, 山岸 良多, 向井 智美, 田部 陽子, 三井田 孝, 関戸 好孝, 村上 優子
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] 肥満誘導性肝がん微小環境におけるSASP制御機構2020

    • Author(s)
      山岸 良多, 蒲池 史卓, 程 イ, 原 英二, 大谷 直子
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] がんと代謝(免疫代謝を含む) 腸内細菌代謝物と肥満関連肝がん2020

    • Author(s)
      大谷 直子, 神谷 知憲, 蒲池 史卓, 山岸 良多
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-20K16309
  • [Presentation] LATS2変異を有した悪性中皮腫に対する合成致死誘導機構の検討2020

    • Author(s)
      鈴木 浩也, 山岸 良多, 向井 智美, 田部 陽子, 三井田 孝, 村上 浩士, 関戸 好孝, 村上 優子[渡並]
    • Organizer
      日本薬学会年会
    • Data Source
      KAKENHI-PROJECT-20K16309
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