ISOZUMI Noriyoshi 五十棲規嘉

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五十棲規嘉イソズミノリヨシ

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Researcher Number	30804512
Other IDs
Affiliation (Current)	2026: 奈良県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2024: 奈良県立医科大学, 医学部, 助教 2020 – 2022: 北陸先端科学技術大学院大学, ナノマテリアルテクノロジーセンター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Basic Section 39040:Plant protection science-related
Keywords	Principal Investigator 相分離 / 構造生物学 / アミロイド線維 / 核磁気共鳴 / 相分離制御因子 / 凝集阻害 / 低複雑性ドメイン / 亜鉛フィンガードメイン Except Principal Investigator 相互作用 / 構造 … More / 機能 / 天然変性タンパク質 / NMR / 液液相分離 / タンパク質 / 相分離 / エフェクター Less

神経変性疾患の治療法開発に向けた亜鉛フィンガードメインの新たな機能の解明Principal Investigator
- Principal Investigator
  
  五十棲規嘉
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Nara Medical University
Functional mechanism of an unstructured protein DN3, one of the effectors of a plant pathogen
- Principal Investigator
  
  OHKI Shinya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 39040:Plant protection science-related
- Research Institution
  Japan Advanced Institute of Science and Technology

All 2025 2024 2021

All Journal Article Presentation

[Journal Article] Graphene Quantum Dots Attenuate TDP-43 Proteinopathy in Amyotrophic Lateral Sclerosis2025
- Author(s)
  Park NY、Heo Y、Yang JW、Yoo JM、Jang HJ、Jo JH、Park SJ、Lin Y、Choi J、Jeon H、Cha SJ、Bae G、Kim D、Kim J、Zeno W、Park JB、Isozumi N、Saio T、Kim SH、Lee H、Hong BH、Nahm M、Lee YH、Hong YB
- Journal Title
  
  ACS Nano
  
  Volume: 19 Issue: 9 Pages: 8692-8710
- DOI
  10.1021/acsnano.4c15283
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K09764
[Journal Article] Unique binding sites of uricosuric agent dotinurad for selective inhibition of renal uric acid reabsorptive transporter URAT12024
- Author(s)
  Fujita K, Isozumi N, Zhu Q, Matsubayashi M, Taniguchi T, Arakawa H, Shirasaka Y, Mori E, Tamai I.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics.
  
  Volume: 390 Issue: 1 Pages: 1-9
- DOI
  10.1124/jpet.124.002096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02641, KAKENHI-PROJECT-23K18181, KAKENHI-PROJECT-24K09764
[Journal Article] Conserved loop of a phase modifier endows protein condensates with fluidity2024
- Author(s)
  Kawamukai Honoka、et al
- Journal Title
  
  bioRxiv
  
  Volume: 601791 Pages: 601791-601791
- DOI
  10.1101/2024.07.03.601791
- Open Access
- Data Source
  KAKENHI-PROJECT-24K01994, KAKENHI-PROJECT-24K09764, KAKENHI-PROJECT-23K18033
[Journal Article] Structure and antimicrobial activity of NCR169, a nodule-specific cysteine-rich peptide of Medicago truncatula2021
- Author(s)
  N. Isozumi, Y. Masubuchi, T. Imamura, M.Mori, H. Koga, S. Ohki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 9923-9923
- DOI
  10.1038/s41598-021-89485-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06049
[Presentation] 亜鉛フィンガードメインは低複雑性ドメインポリマーと結合する2024
- Author(s)
  五十棲規嘉、井口直彦、杉江和馬、森英一朗
- Organizer
  第97回日本生化学会
- Data Source
  KAKENHI-PROJECT-24K09764
[Presentation] Zinc finger domains bind low-complexity domain polymers2024
- Author(s)
  Noriyoshi Isozumi
- Organizer
  The 8th LLPS Symposium/ The Biophysical Society of Japan Joint Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K09764
[Presentation] 根粒特異的ペプチドNCR169の立体構造と新規機能2021
- Author(s)
  五十棲規嘉、大木進野
- Organizer
  日本生化学会北陸支部第38回大会
- Data Source
  KAKENHI-PROJECT-20K06049
[Presentation] Colletotrichum Orbiculare由来のエフェクターCoDN3はCa2+依存的にカルモジュリンと結合する天然変性タンパク質である2021
- Author(s)
  大木進野、五十棲規嘉、高野義孝
- Organizer
  第20回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20K06049

1. OHKI Shinya (70250420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 玉井郁巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 荒川大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISOZUMI Noriyoshi 五十棲 規嘉

五十棲 規嘉 イソズミ ノリヨシ

Research Projects

Research Products

Co-Researchers

神経変性疾患の治療法開発に向けた亜鉛フィンガードメインの新たな機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional mechanism of an unstructured protein DN3, one of the effectors of a plant pathogen

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Graphene Quantum Dots Attenuate TDP-43 Proteinopathy in Amyotrophic Lateral Sclerosis2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unique binding sites of uricosuric agent dotinurad for selective inhibition of renal uric acid reabsorptive transporter URAT12024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conserved loop of a phase modifier endows protein condensates with fluidity2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure and antimicrobial activity of NCR169, a nodule-specific cysteine-rich peptide of Medicago truncatula2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 亜鉛フィンガードメインは低複雑性ドメインポリマーと結合する2024

Author(s)

Organizer

Data Source

[Presentation] Zinc finger domains bind low-complexity domain polymers2024

Author(s)

Organizer

Data Source

[Presentation] 根粒特異的ペプチドNCR169の立体構造と新規機能2021

Author(s)

Organizer

Data Source

[Presentation] Colletotrichum Orbiculare由来のエフェクターCoDN3はCa2+依存的にカルモジュリンと結合する天然変性タンパク質である2021

Author(s)

Organizer

Data Source

ISOZUMI Noriyoshi 五十棲規嘉

五十棲規嘉イソズミノリヨシ