Fujiwara Nobuyuki 藤原信行

… Alternative Names

Researcher Number	30805875
Other IDs
Affiliation (Current)	2021: 岡山理科大学, 獣医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2021: 岡山理科大学, 獣医学部, 助教 2018 – 2020: 山口大学, 大学院医学系研究科, 学術研究員 2016: 山口大学, 連合獣医学研究科, 特別研究員(DC2)
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Veterinary medical science / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator PP6 / がん幹細胞 / cancer stem cell / autophagy / オートファジー / がん肝細胞 / Protein phosphatase / 肝細胞がん / Beclin 1 / 大腸がん … More Except Principal Investigator … More

大腸がん幹細胞で発現上昇するPP6の制御を介した抗がん戦略の構築Principal Investigator
- Principal Investigator
  
  藤原信行
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University of Science
Novel immunotherapy for pancreatic cancer by the multi-HLA binding peptides derived from cancer stemness molecules.
- Principal Investigator
  
  Hazama Shoichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Development of Therapies against Hepatocellular Carcinoma Stem Cells via Regulation of Autophagy ActivityPrincipal Investigator
- Principal Investigator
  
  Nobuyuki Fujiwara
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University of Science
  Yamaguchi University
がん抑制因子Ｂｅｃｌｉｎ　１の新規リン酸化サイトの役割の解明Research Fellow
- Research Fellow
  
  藤原信行
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Veterinary medical science
- Research Institution
  Yamaguchi University

All 2021 2020 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer.2021
- Author(s)
  Yamada Kensuke、Hazama Shoichi、Suzuki Nobuaki、Xu Ming、Nakagami Yuki、Fujiwara Nobuyuki、Tsunedomi Ryouichi、Yoshida Shin、Tomochika Shinobu、Matsukuma Satoshi、Matsui Hiroto、Tokumitsu Yukio、Kanekiyo Shinsuke、Shindo Yoshitaro、Watanabe Yusaku、Iida Michihisa、Takeda Shigeru、Ioka Tatsuya、Ueno Tomio、et al.
- Journal Title
  
  Oncol Lett
  
  Volume: 21 Pages: 1-1
- DOI
  10.3892/ol.2020.12271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-20K17619, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K16364
[Journal Article] Cathepsin B is highly expressed in pancreatic cancer stem like cells and is associated with patients' surgical outcomes2021
- Author(s)
  Fujimoto Takuya、Tsunedomi Ryouichi、Matsukuma Satoshi、Yoshimura Kiyoshi、Oga Atsunori、Fujiwara Nobuyuki、Fujiwara Yasuhiro、Matsui Hiroto、Shindo Yoshitaro、Tokumitsu Yukio、Suzuki Nobuaki、Kobayashi Shogo、Hazama Shoichi、Eguchi Hidetoshi、Nagano Hiroaki
- Journal Title
  
  Oncol Lett
  
  Volume: 21 Pages: 1-1
- DOI
  10.3892/ol.2020.12291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-20K17655, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K16364
[Journal Article] Pancreatic Cancer Stem-Like Cells With High Calreticulin Expression Associated With Immune Surveillance.2021
- Author(s)
  Fujiwara Yasuhiro、Tsunedomi Ryouichi、Yoshimura Kiyoshi、Matsukuma Satoshi、Fujiwara Nobuyuki、Nishiyama Mitsuo、Kanekiyo Shinsuke、Matsui Hiroto、Shindo Yoshitaro、Tokumitsu Yukio、Yoshida Shin、Iida Michihisa、Suzuki Nobuaki、Takeda Shigeru、Ioka Tatsuya、Hazama Shoichi、Nagano Hiroaki
- Journal Title
  
  Pancreas
  
  Volume: 50 Pages: 10-10
- DOI
  10.1097/mpa.0000000000001772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07320, KAKENHI-PROJECT-19K09218, KAKENHI-PROJECT-20K08956, KAKENHI-PROJECT-20K17619, KAKENHI-PROJECT-20K17655, KAKENHI-PROJECT-18K08618, KAKENHI-PROJECT-18K16364
[Journal Article] Protein phosphatase 6 dissociates the Beclin 1/Vps34 complex and inhibits autophagy2021
- Author(s)
  Fujiwara Nobuyuki、Shibutani Shusaku、Ohama Takashi、Sato Koichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 552 Pages: 191-195
- DOI
  10.1016/j.bbrc.2021.02.136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06018, KAKENHI-PROJECT-18K16364
[Journal Article] Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 62020
- Author(s)
  Nobuyuki Fujiwara, Shusaku Shibutani, Yusuke Sakai, Toshio Watanabe, Issei Kitabayashi, Hiroko Oshima, Masanobu Oshima, Hisashi Hoshida, Rinji Akada, Tatsuya Usui, Takashi Ohama*, Koichi Sato.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Pages: 4371-4380
- DOI
  10.1111/cas.14662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-20H03151, KAKENHI-PROJECT-18K06018, KAKENHI-PROJECT-18K16364
[Journal Article] Regulation of Beclin 1 Phosphorylation and Autophagy by PP2A and DAPK32016
- Author(s)
  Nobuyuki Fujiwara, Tatsuya Usui, Takashi Ohama, Koichi Sato
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: inpress
- DOI
  10.1074/jbc.m115.704908
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J07366
[Presentation] Protein phosphatase 6は大腸がん細胞の幹細胞性を制御する2020
- Author(s)
  藤原信行、恒富亮一、硲彰一、友近忍、鈴木伸明、大浜剛、佐藤晃一、永野浩昭
- Organizer
  第163回日本獣医学会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] Protein phosphatase 6は大腸癌細胞の幹細胞性を制御する2019
- Author(s)
  藤原信行、恒富亮一、硲彰一、友近忍、鈴木伸明、大浜剛、佐藤晃一、永野浩昭
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] Protein phosphatase 6は大腸癌細胞の幹細胞性を制御する2019
- Author(s)
  藤原信行、恒富亮一、硲彰一、友近忍、鈴木伸明、大浜剛、佐藤晃一、永野浩昭
- Organizer
  第9回日本プロテインホスファターゼ研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] Protein phosphatase 6 controls tumor malignancy of colon cancer through regulation of cancer stemness.2019
- Author(s)
  Nobuyuki Fujiwara, Ryouichi Tsunedomi, Shoichi Hazama, Nobuaki Suzuki, Takashi Ohama, Shigefumi Yoshino, Hiroaki Nagano
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] Protein phosphatase 6 controls tumor progression of colon cancer.2018
- Author(s)
  藤原信行、恒富亮一、硲彰一、友近忍、鈴木伸明、武田茂、大浜剛、佐藤晃一、吉野茂文、上野富雄、永野浩昭
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] がん幹細胞様細胞と臨床サンプルとの統合解析により同定されたがん幹細胞関連遺伝子2018
- Author(s)
  恒富亮一, 西山光郎, 藤原信行, 松隈聰, 兼清信介, 友近忍, 徳光幸生, 飯田通久, 鈴木伸明, 武田茂, 山本滋, 吉野茂文, 上野富雄, 硲彰一, 永野浩昭
- Organizer
  第26回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] 膵癌幹細胞に高発現した分子calreticulinの臨床的意義2018
- Author(s)
  松隈聰, 吉村清, 藤原康弘, 井上萌子, 布施雅規, 小賀厚徳, 恒富亮一, 徳光幸生, 徳久善弘, 坂本和彦, 兼清信介, 友近忍, 飯田通久, 鈴木伸明, 武田茂, 吉野茂文, 硲彰一, 江口英利, 上野富雄, 永野浩昭
- Organizer
  第26回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18K08618
[Presentation] RAB3B was identified as a gene involved in characteristics of induced cancer stem-like sphere cells2018
- Author(s)
  Ryouichi Tsunedomi, Kiyoshi Yoshimura, Satoshi Matsukuma, Nobuyuki Fujiwara, Shinsuke Kanekiyo, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Shigefumi Yoshino, Shoichi Hazama, Tomio Ueno, Hiroaki Nagano
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] オートファジーによるtype 2A protein phosphataseの制御機構の解明2018
- Author(s)
  藤原　信行、渋谷　周作、坂井祐介、島　礼、渡邊利雄、大島　浩子、大島　正伸、齋藤　達哉、審良　静男、永野　浩昭、臼井　達哉、大浜　剛、佐藤　晃一
- Organizer
  第41回日本分子生物学会総会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] がん幹細胞様細胞と臨床サンプルとの統合解析により同定されたがん幹細胞関連遺伝子2018
- Author(s)
  恒富亮一、西山光郎、藤原信行、松隈聰、兼清信介、友近忍、徳光幸生、飯田通久、鈴木伸明、武田茂、山本滋、吉野茂文、上野富雄、硲彰一、永野浩昭
- Organizer
  第26回日本消化器関連学会週間 (JDDW2018)
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] Protein phosphatase 6は大腸癌の悪性化に関与する2018
- Author(s)
  藤原信行、硲彰一、友近忍、鈴木伸明、武田茂、吉野茂文、大浜剛、佐藤晃一、上野富雄、永野浩昭
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] Elucidation of control mechanism of type 2A protein phosphatase by autophagy2018
- Author(s)
  Nobuyuki Fujiwara, Shusaku T. Shibutani, Yusuke Sakai, Hiroshi Shima, Toshio Watanabe, Hiroko Ohshima, Masanobu Ohshima, Tathuya Saito, Shizuo Akira, Hiroaki Nagano, Tathuya Usui, Takashi Ohama, Koichi Sato
- Organizer
  第13回プロテインホスファターゼ国際カンファレンス Workshop on Frontiers in Phosphatase Research and Drug Discovery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16364
[Presentation] Regulation of Beclin 1 Phosphorylation and Autophagy by PP2A and DAPK32016
- Author(s)
  Nobuyuki Fujiwara, Tatsuya Usui, Koichi Sato, Takashi Ohama
- Organizer
  The 12th International Conference on Protein Phosphatase
- Place of Presentation
  近畿大学（大阪府東大阪市）
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J07366
[Presentation] PP2AとDAPK3はBeclin 1のリン酸化を調節し、オートファジーを制御する2016
- Author(s)
  藤原信行、臼井達哉、大浜剛、佐藤晃一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15J07366
[Presentation] PP2AとDAPK3はBeclin 1のリン酸化を調節し、オートファジーを制御する2016
- Author(s)
  藤原信行、臼井達哉、大浜剛、佐藤晃一
- Organizer
  平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯（長野県茅野市）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-15J07366
[Presentation] 胃癌におけるProtein Phosphatase 6 の役割の解明2016
- Author(s)
  藤原　信行、渋谷　周作、齋藤　達哉、審良　静男、臼井　達哉、大浜　剛、佐藤　晃一
- Organizer
  第159回日本獣医学会
- Place of Presentation
  日本大学　生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15J07366
[Presentation] PP2AとDAPK3はBeclin 1-ATG14L複合体とオートファジーを調節する2015
- Author(s)
  藤原信行、臼井達也、大浜剛、佐藤晃一
- Organizer
  第68回日本薬理学会西南部会
- Place of Presentation
  山口県下関市海峡メッセ下関
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-15J07366
[Presentation] Regulation of Beclin 1 association with Atg14L and autophagy by PP2A and DAPK32015
- Author(s)
  Nobuyuki Fujiwara, Tatsuya Usui, Koichi Sato, Takashi Ohama
- Organizer
  Europhosphatase 2015
- Place of Presentation
  Turku (Finland)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J07366
[Presentation] Regulation of Beclin 1 association with Atg14L and autophagy by PP2A and DAPK32015
- Author(s)
  Nobuyuki Fujiwara, Tatsuya Usui, Koichi Sato, Takashi Ohama
- Organizer
  The 3rd Sapporo summer seminar for one health
- Place of Presentation
  北海道札幌市北海道大学
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J07366

1. Hazama Shoichi (50253159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 永野浩昭 (10294050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 鈴木伸明 (50526910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 恒富亮一 (10420514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. 松井洋人 (60780781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 竹之内寛子 (20749808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OSHIMA Hiroko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. OHAMA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. YOSHIMURA Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 渡辺利雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渋谷周作

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 松隈聰

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Fujiwara Nobuyuki 藤原 信行

Nobuyuki Fujiwara 藤原 信行

藤原 信行 フジワラ ノブユキ

Research Projects

Research Products

Co-Researchers

大腸がん幹細胞で発現上昇するPP6の制御を介した抗がん戦略の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel immunotherapy for pancreatic cancer by the multi-HLA binding peptides derived from cancer stemness molecules.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Therapies against Hepatocellular Carcinoma Stem Cells via Regulation of Autophagy ActivityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん抑制因子Ｂｅｃｌｉｎ １の新規リン酸化サイトの役割の解明Research Fellow

Research Fellow

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cathepsin B is highly expressed in pancreatic cancer stem like cells and is associated with patients' surgical outcomes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pancreatic Cancer Stem-Like Cells With High Calreticulin Expression Associated With Immune Surveillance.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein phosphatase 6 dissociates the Beclin 1/Vps34 complex and inhibits autophagy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 62020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of Beclin 1 Phosphorylation and Autophagy by PP2A and DAPK32016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Protein phosphatase 6は大腸がん細胞の幹細胞性を制御する2020

Author(s)

Organizer

Data Source

[Presentation] Protein phosphatase 6は大腸癌細胞の幹細胞性を制御する2019

Author(s)

Organizer

Data Source

[Presentation] Protein phosphatase 6は大腸癌細胞の幹細胞性を制御する2019

Author(s)

Organizer

Data Source

[Presentation] Protein phosphatase 6 controls tumor malignancy of colon cancer through regulation of cancer stemness.2019

Author(s)

Organizer

Data Source

[Presentation] Protein phosphatase 6 controls tumor progression of colon cancer.2018

Author(s)

Organizer

Data Source

Fujiwara Nobuyuki 藤原信行

Nobuyuki Fujiwara 藤原信行

藤原信行フジワラノブユキ

がん抑制因子Ｂｅｃｌｉｎ　１の新規リン酸化サイトの役割の解明Research Fellow