Toyoshima Syota 豊島翔太

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Toyoshima Shota 豊島翔太

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Researcher Number	30807954
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 助教 2025: 日本大学, 医学部, 客員研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 日本医科大学, 医学部, 助教 2019 – 2020: 日本大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator microRNA / 細胞外小胞 / マスト細胞 / 非アルコール性脂肪性肝疾患 / 肝臓マクロファージ / microRNA-155 / マクロファージ / 非アルコール性脂肪肝炎 / エクソソーム / 2型サイトカイン … More / PRMT5 / IL-5 / タンパク質メチル化 / サイトカイン産生 / ヒトマスト細胞 / アレルギー炎症 / 2型自然リンパ球 Less

NASHにおけるマスト細胞由来細胞外小胞による肝臓マクロファージの機能制御Principal Investigator
- Principal Investigator
  
  豊島翔太
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nippon Medical School
Analysis for the mechanism by which IL-5 production is reinforced by miRNA in exosome from mast cellsPrincipal Investigator
- Principal Investigator
  
  Toyoshima Shota
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
  Nihon University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] マスト細胞が遊離する細胞外小胞中miR155による肝線維化機序の解明2023
- Author(s)
  豊島翔太
- Journal Title
  
  日本医科大学医学会雑誌
  
  Volume: 19
- Data Source
  KAKENHI-PROJECT-22K16056
[Journal Article] Neuro-allergology: Mast cell-nerve cross-talk2022
- Author(s)
  Toyoshima S, Okayama Y
- Journal Title
  
  Allergol. Int.
  
  Volume: 71 Issue: 3 Pages: 288-293
- DOI
  10.1016/j.alit.2022.04.002
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08811, KAKENHI-PROJECT-19K17687
[Journal Article] Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis2021
- Author(s)
  Mishima S, Kashiwakura J, Toyoshima S, Sasaki-Sakamoto T, Sano Y, Nakanishi K, Matsumoto K, Okayama Y
- Journal Title
  
  Sci Rep
  
  Volume: In press Issue: 1
- DOI
  10.1038/s41598-021-84963-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08811, KAKENHI-PROJECT-19K17687
[Journal Article] miR103a-3p in extracellular vesicles from FcεRI-aggregated human mast cells enhances IL-5 production by group 2 innate lymphoid cells2021
- Author(s)
  Toyoshima S, Sakamoto-Sasaki T, Kurosawa Y, Hayama K, Matsuda A, Watanabe Y, Terui T, Gon Y, Matsumoto K, Okayama Y
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: In press Issue: 5 Pages: 1878-1891
- DOI
  10.1016/j.jaci.2021.01.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08811, KAKENHI-PROJECT-19K17687, KAKENHI-PROJECT-19K09980
[Presentation] Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR199a-3p/Cyclooxygenase 2 axis2021
- Author(s)
  Shota Toyoshima, Shintaro Mishima, Jun-ichi Kashiwakura, Tomomi Sasaki-Sakamoto, Yutaka Sano1, Kazuyoshi Nakanishi, Kenji Matsumoto, Yoshimichi Okayama
- Organizer
  第70回日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-19K17687
[Presentation] miR103a-3p in extracellular vesicles from FcεRI-aggregated 1 human mast cells enhances IL-5 production by group 2 innate lymphoid cells2021
- Author(s)
  Shota Toyoshima, Tomomi Sakamoto-Sasaki, Yusuke Kurosawa, Koremasa Hayama, Akira Matsuda, Yasuo Watanabe, Tadashi Terui, Yasuhiro Gon, Kenji Matsumoto, Yoshimichi Okayama
- Organizer
  第70回日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-19K17687
[Presentation] miR103a-3p in extracellular vesicles derived from human mast cells following aggregation of FcεRI enhances IL-5 production from IL-33-stimulated type2 innate lymphoid cells via PRMT52020
- Author(s)
  Shota Toyoshima, Tomomi Sakamoto-Sasaki, Yusuke Kurosawa, Koremasa Hayama, Akira Matsuda, Y Watanabe, Tadashi Terui, Yasuhiro Gon, Kenji Matsumoto, Yoshimichi Okayama
- Organizer
  JSA/WAO Joint Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17687
[Presentation] miR103a-3p in extracellular vesicles derived from human mast cells following aggregation of FceRI enhances IL-5 production from IL-33-stimulated type2 innate lymphoid cells (ILC2) via silencing protein arginine methyltransferase.2019
- Author(s)
  Toyoshima S, Sakamoto-Sasaki T, Matsumoto K, Okayama Y
- Organizer
  WAC (World Allergy Congress) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17687
[Presentation] miRNA103a-3p in extracellur vesicles derived from anti-IgE Ab activated human mast cells enhances IL-5 production in ILC2 in the presence of IL-33.2019
- Author(s)
  Shota Toyoshima, Tomomi Sasaki-Sakamoto, Yusuke Kurosawa, Yasuhiro Gon, Chisei Ra, Kenji Matsumoto, Yoshimichi Okayama.
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K17687
[Presentation] 抗IgE抗体によって活性化したマスト細胞が遊離する細胞外小胞中のmiR103a-3pは, 2型自然リンパ球からのIL-5産生を増強させる.2019
- Author(s)
  豊島翔太, 坂本朋美, 黒澤雄介, 權寧博, 羅智靖, 松本健治, 岡山吉道
- Organizer
  2019年アレルギー・好酸球研究会
- Data Source
  KAKENHI-PROJECT-19K17687
[Presentation] Exosomal miRNA derived from anti-IgE activated human mast cells enhances IL-5 production in ILC2 in the presence of IL-33.2019
- Author(s)
  Shota Toyoshima, Tomomi Sasaki-Sakamoto, Yasuhiro Gon, Chisei Ra, Kenji Matsumoto, Yoshimichi Okayama
- Organizer
  第68回日本アレルギー学会
- Data Source
  KAKENHI-PROJECT-19K17687

1. OKAYAMA Yoshimichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Toyoshima Syota 豊島 翔太

Toyoshima Shota 豊島 翔太

Research Projects

Research Products

Co-Researchers

NASHにおけるマスト細胞由来細胞外小胞による肝臓マクロファージの機能制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis for the mechanism by which IL-5 production is reinforced by miRNA in exosome from mast cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] マスト細胞が遊離する細胞外小胞中miR155による肝線維化機序の解明2023

Author(s)

Journal Title

Data Source

[Journal Article] Neuro-allergology: Mast cell-nerve cross-talk2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] miR103a-3p in extracellular vesicles from FcεRI-aggregated human mast cells enhances IL-5 production by group 2 innate lymphoid cells2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR199a-3p/Cyclooxygenase 2 axis2021

Author(s)

Organizer

Data Source

[Presentation] miR103a-3p in extracellular vesicles from FcεRI-aggregated 1 human mast cells enhances IL-5 production by group 2 innate lymphoid cells2021

Author(s)

Organizer

Data Source

[Presentation] miR103a-3p in extracellular vesicles derived from human mast cells following aggregation of FcεRI enhances IL-5 production from IL-33-stimulated type2 innate lymphoid cells via PRMT52020

Author(s)

Organizer

Data Source

[Presentation] miR103a-3p in extracellular vesicles derived from human mast cells following aggregation of FceRI enhances IL-5 production from IL-33-stimulated type2 innate lymphoid cells (ILC2) via silencing protein arginine methyltransferase.2019

Author(s)

Organizer

Data Source

[Presentation] miRNA103a-3p in extracellur vesicles derived from anti-IgE Ab activated human mast cells enhances IL-5 production in ILC2 in the presence of IL-33.2019

Author(s)

Organizer

Data Source

[Presentation] 抗IgE抗体によって活性化したマスト細胞が遊離する細胞外小胞中のmiR103a-3pは, 2型自然リンパ球からのIL-5産生を増強させる.2019

Author(s)

Organizer

Data Source

[Presentation] Exosomal miRNA derived from anti-IgE activated human mast cells enhances IL-5 production in ILC2 in the presence of IL-33.2019

Author(s)

Organizer

Data Source

Toyoshima Syota 豊島翔太

Toyoshima Shota 豊島翔太